• Journal of the Korean Crystal Growth and Crystal Technology
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• v.7 no.1
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• pp.151-162
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• 1997

The suitability of pivalic acid was confirmed as a secondary temperature standard material. Triple-point cells of pivalic acid were obtained by using combined process of vacuum distillation with zone refining. A detailed description of the purification process was given. The melting curves were used as criteria for determination of purities of pivalic acid. Triple points of these cells with purity of 99.9997% were measured to be $35.956\pm 0.003^{\circ}C$ by using the melting plateau curves. Thus the triple point cells of pivalic acid appear to be able to use for the calibration of thermistor thermometers with moderate precision.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.9
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• pp.3735-3740
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• 2015

Context: Insulin-like growth factor peptides play important roles in regulating cell growth, cell differentiation, and apoptosis, and have been demonstrated to promote the development of colorectal cancer (CRC). Objective: To examine the association of insulin-related biomarkers including insulin-like growth factor-1 (IGF-1), insulin-like growth factor binding protein-3 (IGFBP-3) and C-peptide with CRC risk and assess their relevance in predictive models. Materials and Methods: The odds ratios of colorectal cancer for serum levels of IGF-1, IGFBP-3 and C-peptide were estimated using unconditional logistic regression models in 100 colorectal cancer cases and 100 control subjects. Areas under the receiving curve (AUC) and integrated discrimination improvement (IDI) statistics were used to assess the discriminatory potential of the models. Results: Serum levels of IGF-1 and IGFBP-3 were negatively associated with colorectal cancer risk (OR=0.07, 95%CI: 0.03-0.16, P for trend <.01, OR=0.06, 95%CI: 0.03-0.15, P for trend <.01 respectively) and serum C-peptide was positively associated with risk of colorectal cancer (OR=4.38, 95%CI: 2.13-9.06, P for trend <.01). Compared to the risk model, prediction for the risk of colorectal cancer had substantially improved when all selected biomarkers IGF-1, IGFBP-3 and inverse value of C-peptide were simultaneously included inthe reference model [P for AUC improvement was 0.02 and the combined IDI reached 0.166% (95 % CI; 0.114-0.219)]. Conclusions: The results provide evidence for an association of insulin-related biomarkers with colorectal cancer risk and point to consideration as candidate predictor markers.

• Journal of Korea Water Resources Association
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• v.49 no.12
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• pp.1007-1014
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• 2016

The FORGEX (Focused Rainfall Growth Extension) method was developed to estimate rainfall quantiles in the United Kingdom. This method does not need any regional grouping and can estimate rainfall quantiles with relatively long return period. The spatial dependence formula (ln $N_e$) was derived to consider the distance from growth curve of proper population to the distributed network maximum (netmax) data using the UK rainfall data. For this reason, there is an inaccurate problem in rainfall quantiles when this formula is applied in Korea. In this study, the new formula was derived in order to improve such shortcomings using rainfall data of 64 sites from the Korea Meteorological Administration (KMA). A 42-year period (1973~2014) was taken as the reference period from rainfall data, then the formula was derived using three parameters such as rainfall duration, number of site, area of network. Then the new formula was applied to the FORGEX method for regional rainfall frequency analysis. In addition, rainfall quantiles were compared with those from the UK formula. As a result, the new formula shows more accurate results than the UK formula, in which the FORGEX method by the UK formula underestimates rainfall quantiles. Finally, the new improved formula may estimate accurate rainfall quantiles for long return period.

• Proceedings of the KSR Conference
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• 2007.05a
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• pp.1807-1813
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• 2007

The study aims at analyzing an underground station refuge model using EXODUS, one of the refuge simulation programs. The model for simulation is the Daegu Subway (Joongang-ro station). The details of the accident are referred to as the simulation condition the refuge time of traveling from the $3^{rd}$ basement platform to the $1^{st}$ basement is mainly calculated, with passengers numbering 1,000 including 329 at car 1079, 320 at car 1080, and 360 who are not on board. Reference data is used to set up the position of passengers. CFAST fire simulator is also used, and a fast curve among the $t^2$ growth curves, selected as fire growth scenario. The zone is divided into a total of 24 including 18 at the $3^{rd}$ basement platform and 6 at the $2^{nd}$ basement the $1^{st}$ basement is excluded in the fire simulation, however.

• Environmental Engineering Research
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• v.22 no.4
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• pp.407-416
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• 2017

$CO_2$ emission is increasingly focused by public. Beijing and Tianjin are conceived to be a new economic point of growth in China. However, both of them are suffering serious environmental stress. In order to seek for the effect of socioeconomic factors on the $CO_2$ emission of this region, a novel methodology -symbolic regression- is adopted to investigate the relationship between $CO_2$ emission and influential factors of Beijing and Tianjin. Based on this method, $CO_2$ emission models of Beijing and Tianjin are built respectively. The models results manifested that Beijing and Tianjin own different $CO_2$ emission indicators. The RMSE of models in Beijing and Tianjin are 255.39 and 603.99, respectively. Further analysis on indicators and forecast trend shows that $CO_2$ emission of Beijing expresses an inverted-U shaped curve, whilst Tianjin owns a monotonically increasing trend. From analytical results, it could be argued that the diversity rooted in different development orientation and the mixture of different natural and industrial environment. This research further expands the investigation on $CO_2$ emission of Beijing and Tianjin region, and can be used for reference in the study of carbon emissions in similar regions. Based on the investigation, several policy suggestions are presented.

• Magazine of the Korean Society of Agricultural Engineers
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• v.32 no.1
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• pp.72-86
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• 1990

This study was carried out to get the basic information of irrigation plans for upland crops such as the optimum irrigation level and the project water requirement. Red peppers and cucumbers were cultivated in PVC pot lysimeters filled with 60cm deep clay loam soil. Four tensiometers were installed in each pot to measure the soil water pressure head. Six levels of irrigation were used. The results obtained from this study are summarized as follows: 1.The optimum irrigation level. The irrigation level of FC-PF2.7 was found to be the optimum level for both red pepper and cucumber with respect to the yield and the weight per fruit. In case of FC-PF2.7, total ET during the irrigation period were 1005.2mm for red pepper, and 429.6mm for cucumber, respectively. 2.soil moisture extraction patterns. Average soil moisture extraction patterns (SMEP)during the irrigation period were from 1st soil layer 43% : 32% : 16% : 9% for red pepper and 39% : 34% : 15% : 12% for cucumber, respectively. The extraction ratio of the upper soils showed very large values during the early stage of growth and decreased largely during the middle stage, and became larger in the last stage. 3.The project water requirement. Among the reference crop evapotranspiration(ETo) computation methods presented by FAO, the Penman method was found to be the best. The effective rainfall was computed by a modified USDA-SCS curve number equation. Availability ratios of the total rainfall during irrigation season were 59.2% for red pepper and 48.9% for cucumber, respectively. Net project water requirement of design year are 837.3mm for red pepper. and 502.Smm for cucumber, respectively.

• Journal of the Korean Society for Nondestructive Testing
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• v.27 no.1
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• pp.38-47
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• 2007

The initiation of fatigue cracks in a simulated aircraft structure with a series of rivet holes was detected by acoustic emission(AE), then the crack length was determined by surface acoustic wave(SAW) technique. With the initiation and growth of fatigue cracks, AE events increased intermittently to form a stepwise incremental curve of cumulative AE events whereas the crack length increased more or less monotonically. With the SAW technique employed, the crack sizing for 13 different cracks including some short cracks was performed. With the reference to the measurement by traveling microscope, cracks in the range of $1{\sim}8mm$ long were reliably sized by the SAW technique. Although it was impossible to size the short fatigue cracks in the range shorter than 1 mm, the SAW technique still appeared practically useful for a range of crack lengths often found in aircraft structures.

• Journal of Korean Neurosurgical Society
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• v.66 no.4
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• pp.382-392
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• 2023

Objective : The use of indocyanine green videoangiography (ICG-VA) to assess blood flow in the brain during cerebrovascular surgery has been increasing. Clinical studies on ICG-VA have predominantly focused on qualitative analysis. However, quantitative analysis numerical modelling for time profiling enables a more accurate evaluation of blood flow kinetics. In this study, we established a multiple exponential modified Gaussian (multi-EMG) model for quantitative ICG-VA to understand accurately the status of cerebral hemodynamics. Methods : We obtained clinical data of cerebral blood flow acquired the quantitative analysis ICG-VA during cerebrovascular surgery. Varied asymmetric peak functions were compared to find the most matching function form with clinical data by using a nonlinear regression algorithm. To verify the result of the nonlinear regression, the mode function was applied to various types of data. Results : The proposed multi-EMG model is well fitted to the clinical data. Because the primary parameters-growth and decay rates, and peak center and heights-of the model are characteristics of model function, they provide accurate reference values for assessing cerebral hemodynamics in various conditions. In addition, the primary parameters can be estimated on the curves with partially missed data. The accuracy of the model estimation was verified by a repeated curve fitting method using manipulation of missing data. Conclusion : The multi-EMG model can possibly serve as a universal model for cerebral hemodynamics in a comparison with other asymmetric peak functions. According to the results, the model can be helpful for clinical research assessment of cerebrovascular hemodynamics in a clinical setting.

• Korean Journal of Food Science and Technology
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• v.29 no.6
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• pp.1241-1247
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• 1997

Gel-type fermented milk was prepared from milk or mixture of milk and apple juice/grape juice. Acid production (pH change) and growth of Lactobacillus acidophilus (KCTC 2182) were studied. The effects of juice addition on sensory property of fermented milk were also studied. The pH value of samples containing mixture of milk and apple juice/grape juice (25 mL : 25 mL to 5 mL : 45 mL) was lower than that of milk sample. However, number of viable cells of L. acidophilus at 21 hr in milk and samples containing juices was similar. During lactic fermentation for 24 hr, pH of all samples dropped significantly between 6 hr and 21 hr. pH values of mixture of milk and juices were lower than that of milk sample. Growth curve showed that lag phase continued to approximately 3 hr and log phase continued to approximately 15 hr in all samples. Number of viable cells in all samples was similar Sensory evaluation showed that overall acceptability of fermented milk prepared from apple juice/grape juice and milk (15 mL : 35 mL or 5 mL : 45 mL) was better than that of reference sample. The optimum ratio of mixture of juice and milk was 15 mL : 35 mL. The score values of sensory test of fermented milk prepared from mixture of grape juice and milk were slightly higher than those of mixture of apple juice and milk.