• 한국임상수의학회지
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• 제40권2호
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• pp.130-134
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• 2023

A 12-year-old Standard Poodle presented with intermittent weakness and occasional dyspnea at the Veterinary Medicine Teaching Hospital of Kangwon National University. A grade of 4 out of 6 systolic murmur with an irregular tachycardic rhythm was auscultated on both sides of the chest. Systolic blood pressure was 140 mmHg. Panting was noticed in the hospital, but there was no crackle sound. Blood analysis revealed mild increases in liver panel levels (alanine aminotransferase 149 [reference interval, 19-70] U/L; and alkaline phosphatase, 185 [reference interval, 15-127] U/L) and severe increases in cardiac biomarker levels (n-terminal pro-brain natriuretic peptide, 4169 [reference interval, 50-900] pmol/L; and cardiac troponin I, 0.22 [reference interval, 0.03-0.12] ng/mL). On electrocardiography, irregularly irregular supraventricular tachycardic rhythm with an f-wave and no distinct p-wave was observed. Generalized cardiomegaly with an enlarged right atrium and left ventricle was confirmed on thoracic radiography. Moreover, hepatomegaly and an enlarged caudal vena cava were observed. Echocardiographic evaluation revealed a fibromuscular diaphragm in the right ventricle. Because of the obstructive lesion in the right ventricle, the right atrium and ventricle were enlarged (right atrial area index, 38.82 cm²/m² [reference interval, 4.2-10.2 cm²/m²]; right ventricle end-diastolic area index, 14.152 cm²/m² [reference interval, 4.9-10.92 cm²/m²]). Accordingly, the patient was diagnosed with double-chambered right ventricle (DCRV). Pimobendan, furosemide, enalapril, diltiazem, and S-adenosylmethionine (SAMe) were prescribed, and all symptoms were relieved. DCRV is a right-sided congenital heart defect resembling pulmonic valve stenosis. If symptoms are not severe, medical therapy can be facilitated without surgery or the balloon dilation.

• 대한산업공학회지
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• 제24권2호
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• pp.261-278
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• 1998

The paper represented the lower extremity muscle model as four rigid-body segments: trunk, shank, and foot. We transformed their tibial data into our shank data by rotating their tibial X and Y axes by 5.483 degrees, so the revised coordinate data used to translating the origin of their tibial reference frame to our shank reference frame. According to weight of subject, physiological cross-setional area(PCSA) of each lower extremity muscle was calculated by scaling those data by Brand. The objectives of this paper are to investigate the variations of the recruitment patterns of the lower extremity muscles, and to analyze the changes of the role assigned to each muscle during the seated foot operation. For exertion levels, the transition point of type F motor unit of each muscle is inferred by analyzing the electromyogram at the seated postures. Also, for predetermined seated foot operations exertion levels, the recruitment pattern and the changes of the role assigned are identified in the continuous exertion, by analyzing the electromyogram changes due to the accumulated muscle fatigue. This study can be used to design and to assess the pedals and foot-related equipments design.

• 지역사회간호학회지
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• 제28권1호
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• pp.13-22
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• 2017

Purpose: The aim of this study is to examine the reciprocal causal relationship between social activities and health with reference to the cognitive function level among community-dwelling older adults. Methods: We conducted a longitudinal data analysis using the $4^{th}$ (Time 1) and $5^{th}$ (Time 2) waves from the Korean Longitudinal Study of Ageing adopting cross-lagged panel analysis (CLPA). Results: A total of 3,473 community-dwelling older adults were included in the analysis: 2,053 in the normal cognitive function group, 912 in the mild cognitive impairment group, and 508 in the moderate to severe cognitive impairment group. The CLPA revealed that higher levels of social activities at Time 1 significantly influenced better subjective health perception at Time 2 in all three groups. In addition, better subjective health perception at Time 1 significantly influenced higher levels of social activities at time 2 only in the normal cognitive function group. Conclusion: This study demonstrates that participating in social activities has positive effects on health regardless of the cognitive function level in community-dwelling older adults. This finding suggests that there is a need to develop strategies that can be used to encourage older adults with cognitive decline to maintain participation in social activities.

• 대한전자공학회논문지SD
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• 제40권12호
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• pp.24-30
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• 2003

본 논문에서는 첨두 검출기의 구조를 개선함으로써 정착시간(settling time)을 더욱 단축시킬 수 있는 적응형 기준레벨자동 발생회로를 제안했다. 제안한 기준레벨 자동 발생회로에 대해 비슷한 정착시간을 설정하였을 때에 오차전압비율이 기존 구조에 비해 절반 이하로 줄일 수 있어 정착시간을 상당량 개선할 수 있음을 해석을 통해 밝혔다. 아울러 상용 파운드리(foundry)를 이용하여 1.25G EPON 시스템용 버스트 모드기준레벨 자동 발생회로를 설계한 결과 동적 영역(dynamic range)이 40㏈인 입력신호에 대해 6㎱ 라는 매우 짧은 시간 이내에 기준 레벨을 생성해 내는 결과를 얻을 수 있었다.

• Steel and Composite Structures
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• 제23권1호
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• pp.31-40
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• 2017

This article aims at presenting multi objective optimization of parameters that affect crashworthiness characteristics of bi-tubular structures using Taguchi method with grey relational analysis. To design the experiments, the $L_9$ orthogonal array has been used and based on that, the inner tubes have been fabricated by varying the three influence factors such as reference diameter, length difference and numbers of sides of the polygon with three levels, but all the outer cylinders have the same diameter and length 90 mm and 135 mm respectively. Then, the tailor made bi-tubular steel structures were subjected into quasi static axial compression. From the test results it is found that the crushing behaviors of bi-tubular structures with different combinations were fairly significant. The important responses (crashworthiness indicators) specific energy absorption and crush force efficiency have been evaluated from load - displacement curve. Finally optimal levels of parameters were identified using grey relational analysis, and significance of parameters was determined by analysis of variance. The optimum crashworthiness parameters are reference diameter 80 mm, length difference 0 mm and number of sides of polygon is 3, i.e., triangle within the selected nine bi-tube combinations.

• 경영과학
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• 제32권3호
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• pp.55-70
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• 2015

The main objective of this study is to investigate the moderating roles of the competitor's pricing strategy and the degree of consumer's risk-aversion on perceived risk and perceived benefit in responding to price increases and package downsizing. Based on Prospect Theory, several prior researches find that consumers perceive increased price as more loss than package downsizing and perceive package downsizing as more benefit than increased price. We extend these behavioral economics approach using the reference effect of competitor's pricing strategy. We focus on consumer heterogeneity on risk-aversion, measure the degree of consumer's risk-aversion, and divide the consumers into two groups of high levels of risk-aversion vs. low levels of risk-aversion. We find that the firm's pricing strategies of both price increases and package downsizing do not significantly influence the perceived benefit for relatively low risk-aversion consumers. We find that when the firm reduce the package size, relatively high risk-aversion consumers perceived more benefit and had higher purchase intention compared to price increases. We also find that the competitor's pricing strategies do not significantly influence the consumer's response for relatively low risk-aversion consumers. For relatively high risk-aversion consumers, they perceived more loss when the firm has different pricing strategy from the competitor's.

• 한국지하수토양환경학회지:지하수토양환경
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• 제25권4호
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• pp.87-97
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• 2020

In this study, the applicability of the geostatistical evolution strategy as an inverse analysis method of estimating hydraulic properties of small-scale basin was tested. The geostatistical evolution strategy is a type of data assimilation method that can effectively estimate aquifer hydraulic conductivity by combining a global optimization model of the evolution strategy and a local optimization model of the ensemble Kalman filtering. In the applicability test, the geometry, hydraulic boundary conditions, and the distribution of groundwater monitoring wells of Hanlim-Eup were employed. On the other hand, a synthetic hydraulic conductivity distribution was generated and used as the reference property for ease of estimation quality assessment. In the estimations, two different cases were tested where, in Case I, both groundwater levels and hydraulic conductivity measurements were assumed to be available, and only the groundwater levels were available, in Case II. In both cases, the reference and estimated hydraulic conductivity fields were found to show reasonable similarity, even though the prior information for estimation was not accurate. The ability to estimate hydraulic conductivity without accurate prior information suggests that this method can be used effectively to estimate mathematical properties in real-world cases, many of which little prior information is available for the aquifer conditions.

• 보건행정학회지
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• 제32권2호
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• pp.180-189
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• 2022

Background: Social support contributes directly and indirectly to maintaining physical, mental, and social well-being. The aim of the study was to identify the impact of social support on self-rated health among Korean industrial accident workers. Methods: This study used data from the panel study of workers' compensation insurance (PSWCI). The final subjects were 2,759 workers who responded to a 2018 to 2020 PSWCI. Social support was defined as social contact with friends, neighbors, family, and social participation activities like religious activity, social activity, and club activity. Multivariate logistic regression analysis was performed to investigate causal relationships between social support and self-rated health using a generalized estimating equation model. Results: Proportion of workers' good self-rated health steadily increased (2018: n=1,447, 63.2%; 2019: n=1,542, 66.2%; 2020: n=1,653, 67.3%). Higher levels of social contacts with friend (worse: reference; same: β=0.442) and higher levels of social activity (yes: reference; no: β=-0.173) were especially associated with good self-rated health. Conclusion: This study confirmed social support positively influenced self-rated health among the self-rated health of industrial injured workers. The results of this study suggested that recovery policies that the government served should include programs enhancing social support for improving health among industrial injured workers.

• 산업경영시스템학회지
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• 제39권2호
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• pp.54-63
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• 2016

As technology has developed and cost for data processing has reduced, big data market has grown bigger. Developed countries such as the United States have constantly invested in big data industry and achieved some remarkable results like improving advertisement effects and getting patents for customer service. Every company aims to achieve long-term survival and profit maximization, but it needs to establish a good strategy, considering current industrial conditions so that it can accomplish its goal in big data industry. However, since domestic big data industry is at its initial stage, local companies lack systematic method to establish competitive strategy. Therefore, this research aims to help local companies diagnose their big data capabilities through a reference model and big data capability assessment system. Big data reference model consists of five maturity levels such as Ad hoc, Repeatable, Defined, Managed and Optimizing and five key dimensions such as Organization, Resources, Infrastructure, People, and Analytics. Big data assessment system is planned based on the reference model's key factors. In the Organization area, there are 4 key diagnosis factors, big data leadership, big data strategy, analytical culture and data governance. In Resource area, there are 3 factors, data management, data integrity and data security/privacy. In Infrastructure area, there are 2 factors, big data platform and data management technology. In People area, there are 3 factors, training, big data skills and business-IT alignment. In Analytics area, there are 2 factors, data analysis and data visualization. These reference model and assessment system would be a useful guideline for local companies.

• 한국동물생명공학회지
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• 제34권4호
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• pp.280-291
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• 2019

Potential utility of 14 candidate housekeeping genes as normalization reference for RT-qPCR analysis with developmental samples (fertilized eggs to late veliger larvae) in Pacific abalone Haliotis discus hannai was evaluated using four different statistical algorithms (geNorm, NormFinder, BestKeeper and comparative ΔCT method). Different algorithms identified different genes as the best candidates, and geometric mean-based final ranking from the most to the least stable expression was as follow: RPL5, RPL4, RPS18, RPL8, RPL7, UBE2, RPL7A, GAPDH, RPL36, PPIB, EF1A, ACTB and B-TU. The findings were further validated via relative quantification of metallothionein (MT) transcripts using the stable and unstable reference genes, and expression levels of MT were greatly influenced according to the choice of reference genes. In overall, our data suggest that RPL5 and RPS18, either singly or in combination, are appropriate for normalizing gene expression in developmental samples of this abalone species, whereas ACTB, B-TU and EF1A are less stable and not recommended. In addition, our findings propose that standard deviations in geometric ranking as well as geometric mean itself should also be taken into account for the final selection of reference gene(s). This study could be a useful basis to facilitate the generation of accurate and reliable RT-qPCR data with developmental samples in this abalone species.