• Journal of Korean Society on Water Environment
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• v.22 no.2
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• pp.209-214
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• 2006

The purpose of this study is to improve the stream water quality by the experimental hybrid constructed wetland system. It consisted of the water layer, sand bed planted reeds, irises and roses, gravel bed, yellow-soil media bed and a flow shifter (FS) which can reverse top and bottom flow in the middle of the wetland. The organic compounds and nitrogen removal efficiencies varied with the seasons, namely temperature change. In summer, the mean efficiencies of COD and TN in the outflow from this wetland system were 63.4 and 48.0% and shown the highest, respectively, whereas, the suspended solids and phosphorus removal efficiencies seemed to be less affected by temperature. As a result of inspecting the decreasing trend of pollutants, nitrification-denitrification in the wetland was the major removal mechanism for nitrogen, the nitrogen reduction was especially enhanced by the application of a FS in the wetland, and phosphorus reduction was mainly occurred as a consequence of adsorption of the yellow-soil media.

• Journal of The Korean Society of Agricultural Engineers
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• v.54 no.3
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• pp.103-111
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• 2012

Works for dam heightening plan have dual purposes: flood disaster prevention by securing additional storage volume and river ecosystem conservation by supplying stream maintenance flow. Now, the dam heightening project is in progress and there are 93 dam heightened reservoir. After the dam heightening project, 2.2 hundred million ton of flood control volume in reservoirs will be secured. Thus it is necessary to evaluate the effects of the dam heightening project on watershed hydrology and stream hydraulics, and resulting flood damages. This study was aimed to assess the impact of outflow from the dam heightened reservoir group on the Whangryong river design flood. The HEC-HMS (Hydrologic Engineering Center-Hydrologic Modeling System) model was used for estimating flood discharge, while HEC-5 (Hydrologic Engineering Center-5) was used for reservoir routing. This study analysed flood reduction effect on 100yr and 200yr return periods about the before and after heightening of agricultural dams. Based on the results of this study, the reduction of flood peak discharge at downstream of the reservoir group was estimated to be about 41% and 53% for 100yr and 200yr frequencies, respectively.

• Proceedings of the Korea Water Resources Association Conference
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• 2021.06a
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• pp.126-126
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• 2021

Stormwater reduction plays an important role in the safety and resilience to flooding in urban areas. Due to rapid climate change, the world is experiencing abnormal climate phenomena, and sudden floods and concentrated torrential rains are frequently occurring in urban basins and the amount of outflow due to stormwater increases. In addition, the damage caused by urban flooding and inundation due to extreme rainfall exceeding the events that occurred in the past increases. To solve this problem, water supply, drainage, and water supply for sustainable urban development, the water management paradigm is shifting from sewage maintenance to water circulation and water-sensitive cities. So, in this study, The purpose of this study is to examine measures to increase the resilience of urban ecosystem systems for urban excellence reduction by analyzing the effects of green infra structures and LID techniques and evaluating changes in resilience. In this study, for simulating and analysis of runoff for various stormwater patterns and LID applications, Storm Water Management Model (SWMM) was used.

• Journal of Industrial Technology
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• v.29 no.A
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• pp.111-122
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• 2009

In this study, flood stage was computed by HEC-RAS, 1-D numerical analysis model and FESWMS-2DH, 2-D numerical model. Flood stages computed by two different models were compared for straight line, dot axle watercourse, dead-zone watercourse, section sudden-changing watercourse, and curved watercourse. From the results, flow velocity and water level were similar in straight watercourse and dot-reduction watercourse. However, there was difference of flow velocity and water level in dead-zone watercourse, sudden expansion, dot-reduction, and curve-watercourse. This result might be influenced by rapid change of watercourse due to dead-zone, the angle of inflow and outflow, and the curvature. Especially in this study, numerical model was applied to Wol-Song-Cheon at Chuncheon in order to analyze the effect of flood stage by two different models. By flowing properties around the bridge and confluence of rivers, it was found that flow velocity and water level was changed. Therefore, it was concluded that a lot of uncertainties are contained in the present bank.

• Tribology and Lubricants
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• v.33 no.1
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• pp.1-8
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• 2017

Drag torque reduction in a wet clutch pack is a key aspect of the design process of the dual clutch transmission (DCT) system. In order to reduce the drag torque caused by lubricant shear resistance, recently developed wet clutch pack systems of DCT, as well as automatic transmission and other four-wheel drive (4WD) couplings, frequently utilize wavy wet clutch pads. Therefore, wavy shape of friction pad are made on the groove patterns like waffle pattern for the reduction of drag torque. Additionally, the groove patterns are designed with larger channels at several locations on the friction pad to facilitate faster outflow of lubricant. However, channel performance is a function of the waviness of the friction pad at the location of the particular channel. This is because the discharge sectional area varies according to the waviness amplitude at the location of the particular channel. The higher location of the additional channel on the friction pad results in a larger cross-sectional area, which allows for a larger flow discharge rate. This results in reduction of the drag torque caused by the shear resistance of DCTF, because of marginal volume fraction of fluid (VOF) in the space between the friction pad and separator. This study computes the VOF in the space between the friction pad and separator, the hydrodynamic pressure developed, and the shear resistance of friction torque, by using CFD software (FLUENT). In addition, the study investigates the dependence of these parameters on the location and waviness amplitude of the channel pattern on the friction pad. The paper presents design guidelines on the proper location of high waviness amplitude on wavy friction pads.

• The Korean Journal of Physiology and Pharmacology
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• v.28 no.4
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• pp.345-359
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• 2024

Deposition of extracellular matrix (ECM) in the trabecular meshwork (TM) increases aqueous humour outflow resistance leading to elevation of intraocular pressure (IOP) in primary open-angle glaucoma, which remains the only modifiable risk factor. Resveratrol has been shown to counteract the steroid-induced increase in IOP and increase the TM expression of ECM proteolytic enzymes; however, its effects on the deposition of ECM components by TM and its associated pathways, such as TGF-β-SMAD signalling remain uncertain. This study, therefore, explored the effects of trans-resveratrol on the expression of ECM components, SMAD signalling molecules, plasminogen activator inhibitor-1 and tissue plasminogen activator in dexamethasone-treated human TM cells (HTMCs). We also studied the nature of molecular interaction of trans-resveratrol with SMAD4 domains using ensemble docking. Treatment of HTMCs with 12.5 µM trans-resveratrol downregulated the dexamethasone-induced increase in collagen, fibronectin and α-smooth muscle actin at gene and protein levels through downregulation of TGF-β1, SMAD4, and upregulation of SMAD7. Downregulation of TGF-β1 signalling by trans-resveratrol could be attributed to its effect on the transcriptional activity due to high affinity for the MH2 domain of SMAD4. These effects may contribute to resveratrol's IOP-lowering properties by reducing ECM deposition and enhancing aqueous humour outflow in the TM.

• Korean Circulation Journal
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• v.52 no.8
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• pp.563-575
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• 2022

Hypertrophic cardiomyopathy (HCM) is one of the most common inheritable cardiomyopathies. Contemporary management strategies, including the advent of implantable cardioverter-defibrillators and effective anticoagulation, have substantially improved the clinical course of HCM patients; however, the disease burden of HCM is still high in Korea. Sudden cardiac death (SCD), atrial fibrillation and thromboembolic risk, dynamic left ventricular outflow tract (LVOT) obstruction, and heart failure (HF) progression remain important issues in HCM. SCD in HCM can be effectively prevented with implantable cardioverter-defibrillators. However, appropriate patient selection is important for primary prevention, and the 5-year SCD risk score and the presence of major SCD risk factors should be considered. Anticoagulation should be initiated in all HCM patients with atrial fibrillation regardless of the CHA2DS2-VASc score, and non-vitamin K antagonist oral anticoagulants are the first option. Symptomatic dynamic LVOT obstruction is first treated medically with negative inotropes, and if symptoms persist, septal reduction therapy is considered. The recently approved myosin inhibitor mavacamten is promising. HF in HCM is usually related to diastolic dysfunction, while about 5% of HCM patients show reduced left ventricular ejection fraction <50%, also referred to as "end-stage" HCM. Myocardial fibrosis plays an important role in the progression to advanced HF in patients with HCM. Patients who do not respond to guideline-directed medical therapy can be considered for heart transplantation. The development of imaging techniques, such as myocardial deformation on echocardiography and late gadolinium enhancement on cardiac magnetic resonance, can provide better risk evaluation and decision-making for management strategies in HCM.

• Journal of Korean Society on Water Environment
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• v.33 no.3
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• pp.247-255
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• 2017

This research was conducted to analyze removal efficiencies of non-point pollution source (NPS) in low impact development (LID) facilities with vegetation. In this research, removal efficiencies of NPS were calculated using rainfall monitoring data for 5 years in grassed swale (GS) and vegetative filter strip (VFS). TSS was greater than other pollutants, and it ranged 11.9 ~ 351.7 mg/L in GS and 12.8 ~ 350.7 mg/L in VFS. Outflow EMCs were reduced than inflow EMCs, overall removal efficiencies of NPS were 67 ~ 86% in GS and 63 ~ 91% in VFS. 50 % reduction efficiency of rainfall runoff was observed between inflow and outflow in each LID facility. TSS removal efficiency in GS and VFS was correlated with rainfall characteristics. The rainfall for TSS removal efficiency over 50% was determined about 31 mm, 34 mm and average rainfall intensity was 3.0 mm/hr, 3.9 mm/hr in GS and VFS. Therefore, GS and VFS were regarded effective LID facilities as removal of pollutants and rainfall runoff. Also, this research result can be used as an important data for management of NPS.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.4
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• pp.1976-1981
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• 2011

In this study, the optimal sewer layout model(Lee, J.H., 2010)[1] was applied to verify the reduction effect of urban inundation in the optimal sewer networks, which designed by this optimal model, for various artificial rainfall events in urban areas. Then the optimal model was developed by Lee, J.H. to minimize the peak outflow at outlet in sewer network. The applied rainfall events are two types. One is the rainfall event which the double peak occurs between specific time distance continuously. The other is the continuous rainfall event with specific rainfall intensity. As the result, in two applied rainfall types, the peak outflows at outlet were reduced in the optimal sewer networks which designed the optimal sewer layout model of Lee, J.H.. Therefore, the peak outflow is reduced because the inflows at each manhole are distributed in the whole sewer networks, it's not delay of inflows by this optimal model.

• Journal of Chest Surgery
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• v.32 no.1
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• pp.10-15
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• 1999

Background: Mitral valve replacement with chordal preservation in patients with mitral regurgitation has been proved to be beneficial for left ventricular function and for reduction of postoperative complication. However, in patients with mitral stenosis, the effectiveness of the technique is controversial. It is not easy to insert prosthetic valve without left ventricular outflow tract obstruction and prosthetic valve leaflet motion hinderance. Material and Method : Five patients with mitral stenosis and seven patients with mitral stenoinsufficiency underwent mitral valve replacement with preservation of mitral subvalvular apparatus. Thickened and calcified leaflets are made thin by peeling off the thickened and calcified part. Commissurotomy was done and anterior leaflet was incised 2 mm apart from the annulus and then divided into two segments. Anterolateral and posteromedial segments including strut chordae, were reattached to mitral commissural area, respectively. Result: There was no evidence of prosthetic valve dysfunction, paravalvular leakage, left ventricular outflow tract obstruction, complications and operative or late deaths. Conclusion: We conclude that mitral vlave replacement with chordal preservation was safe and effective technique for the patients with mitral stenotic disease.