• Bulletin of the Korean Chemical Society
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• 제23권12호
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• pp.1695-1696
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• 2002

• 대한화학회지
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• 제61권5호
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• pp.244-250
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• 2017

Reduction of (${\pm}$)-3-ketoproline ethyl ester (1) by $NaBH_4$ in the presence of $CaCl_2$ and $MgCl_2$ as the chelating agents gave selective products cis-3(R/S)-alcohols, while reduction by $NaBH_4$ alone or chelated with $NiCl_2$ and $AlBr_3$ gave mixtures of cis- and trans-alcohols. The reduction of (${\pm}$)-1 by various vegetables however, gave exclusively the cis-alcohol as the major and trans-alcohol as the minor. On the contrary, reduction of (${\pm}$)-1 by carrot afforded a mixture of cis- and trans-alcohols, in which the trans-alcohol exists as the major product. In addition, we found that this biocatalyst selectively converted S-enantiomer of (${\pm}$)-1 to the cis-alcohol, and R-enantiomer to a mixture of cis- and trans-alcohols with cis-alcohol as the major product. This fact prompted us to use various fresh plant tissues for stereoselective reduction of diverse types of pyrrolidinones, as its stereoselectivity towards racemic mixtures is higher compared to that using chemical reducing agents.

• 생약학회지
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• 제30권2호
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• pp.151-157
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• 1999

In order to find less toxic antiherpetic agents, the effect of natural quercetin on the plaque formation of herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) was studied in vitro in cell culture monolayers employing the technique of viral plaque reduction assay. Quercetin caused a concentration-dependent reduction in the plaque formation of herpesviruses. It also exhibited more potent antiherpetic activity on HSV-1 with effective concentration $(EC_{50})$ of $18.7\;{\mu}g/ml$ than on HSV-2 with $EC_{50}$ of $24.5\;{\mu}g/ml$. The combined antiherpetic effects of quercetin with nucleoside antiherpetic agents, acyclovir and vidarabine, were examined on the multiplication of these two strains of herpesviruses in Vero cells by the combination assay. The results of combination assay were evaluated by the combination index (CI) that was calculated by the multiple drug effect analysis. The combinations of quercetin with acyclovir on HSV-1 and HSV-2 showed more potent synergism with CI values of $0.19{\sim}0.89$ for 50%, 70%, 90% effective levels than those with vidarabine with CI values of $0.43{\sim}1.46$.

• Geomechanics and Engineering
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• 제16권4호
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• pp.375-384
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• 2018

Unconfined compressive strength (UCS) of high plasticity clayey soil mixed with 5 and 10 % of Portland cement and four chemical agents such as sodium hexametaphosphate, aluminum sulfate, sodium carbonate, and sodium silicate with 0, 5, 10, and 20% concentrations was comparatively evaluated. The individual and combined effects of the cement and chemical agents on the UCS of the soil mixture were investigated. The strength of the soil-cement mixture generally increases with increasing the cement content. However, if the chemical agent is added to the mixture, the strength of the cement-chemical agent-soil mixture tends to vary depending on the type and the amount of the chemical agent. At low concentrations of 5% of aluminum sulfate and 5% and 10% of sodium carbonate, the average UCS of the cement-chemical agent-soil mixture slightly increased compared to pure clay due to increasing the flocculation of the clay in the mixture. However, at high concentrations (20%) of all chemical agents, the UCS significantly decreased compared to the pure clay and clay-cement mixtures. In the case of high cement content, the rate of UCS reduction is the highest among all cement-chemical agent-soil mixtures, which is more than three times higher in comparison to the soil-chemical agent mixtures without cement. Therefore, in the mixture with high cement (> 10%), the reduction of the USC is very sensitive when the chemical agent is added.

• Elastomers and Composites
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• 제58권2호
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• pp.65-69
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• 2023

To reduce the weight of the engineering plastic Nylon 6 resin, two high-temperature foaming agents, p-toluenesulfonyl semicarbazide (PTSS) and 5-phenyltetrazole (5-PT) (0-10 phr), were added and foamed without other additives. We investigated the effects of the foaming agent type and content on the foam density (g/cm³) and percent weight reduction rate of the Nylon 6 foam, and 5-PT exhibited better foaming performance than PTSS. In the case of 5-PT, the weight reduction rate was above 36% when the blowing agent content was 1.5 phr or higher, indicating that 5-PT is an effective blowing agent for reducing the Nylon 6 foam weight. Additionally, we studied the effect of the nucleating agent Talc content (0-0.4 phr) on Nylon 6 foaming, and the nucleating agent Talc considerably reduced foaming.

• 한국미생물·생명공학회지
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• 제25권3호
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• pp.335-337
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• 1997

In this study, we show a convenient MTT assay for detect the susceptibility of yeast-like form of Trichosporon beigelii against antifungal agents. This assay was developed based on mitocondrial respiration by determining reduction of 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) to formazan. Cells of T beigelii are seeded into 96-well microtiter plates, and antifungal agents, amphotericin B, magainin and CA-ME hybrid peptide were added with various concentrations. After 24 hr incubation, MTT was added, then incubations were continued for 4 hr. Formazan formation was quantified photometrically after extraction of the formazan with acid sodium dodesyl sulfate (SDS). From this assay, we could obtained MICs of antifungal agents against T. beigelii. The presented method can easily be used as an effective methods to assess the antiftingal action of various agents on yeasts with minimal amounts of antifungal agents.

• 인터넷정보학회논문지
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• 제6권3호
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• pp.45-54
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• 2005

최근 무선 인터넷 서비스를 위한 다양한 기반기술이 연구되고 있으며, WAP(Wireless Application Protocol) 포럼에서는 기존의 유선인터넷 프로토콜과 무선 WAP 프로토콜간의 상호변환을 담당하는 WAP 게이트웨이를 제안하였다. 본 논문에서는 제한적인 환경을 가지는 이동무선통신망에서의 효율향상을 위한 방법의 일환으로써, WAP 게이트웨이를 위한 에이전트들을 설계하고 구현하였다. WAP 게이트웨이 에이전트들인 CSA(Client Side Agent)와 SSA(Sewer Side Agent)는 이동 WAP 단말기와 WAP 게이트웨이에 각각 위치하며, 패킷 헤더 데이터축소와 데이터 차이분석을 통한 데이터축소 방법들을 이용하여 이동무선통신 환경에서의 통신효율을 향상시킨다 구현된 에이전트들이 제대로 동작된다는 것을 입증하기 위하여 Phone.com의 인터넷폰 에뮬레이터를 사용하였다. 실험 결과, WAP 게이트웨이만을 이용한 데이터 전송량에 비하여, 본 논문에서 구현한 에이전트들을 이용하면 데이터 전송량을 $20\%$ 내지 $35\%$가량 줄일 수 있음을 알 수 있었다.

• Bulletin of the Korean Chemical Society
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• 제26권4호
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• pp.652-654
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• 2005

• International Journal of Control, Automation, and Systems
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• 제5권3호
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• pp.295-306
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• 2007

It is well known that mathematical solutions for multi-agent planning problems are very difficult to obtain due to the complexity of mutual interactions among multi-agents. Most of the past research results are thus based on the probabilistic completeness. However, the practicality and effectiveness of the solution from the probabilistic completeness is significantly reduced by heavy computational burden. In this paper, we propose a practically applicable solution technique for multi-agent planning problems, which assures a reasonable computation time and a real world application for more than 3 multi-agents, for the case of general shaped paths in agent movement. First, to reduce the computation time, an extended collision map is developed and utilized for detecting potential collisions and obtaining collision-free solutions for multi-agents. Second, a priority for multi-agents is considered for successive and interactive modifications of the agent movements with lower priority. Various solutions using speed reduction and time delay of the relevant agents are investigated and compared in terms of the computation time. A practical implementation is finally provided for three different types of agents to emphasize the effectiveness of the proposed interactive approach to multi-agent planning problems.

• 한국수소및신에너지학회논문집
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• 제22권3호
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• pp.340-348
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• 2011

Effects of various inorganic-metal oxide (Zr, Zn, Si, Al and Ca as promoters and stabilizers) additive on the reduction rate of iron oxide and the composition of forming hydrogen using the steam-iron cycle operation was investigated. The reduction rate of redox agent with additive was determined from weight change by TGA. The changes of weight loss and reduction rate according to redox agent with various additive affected the hydrogen purity and cycle stability of the process. The cyclic micro reactor showed that hydrogen purity exceeding 95% could be obtained by the water splitting with Si/Fe, Zn/Fe, Zr/Fe redox agents. The redox agents with these elements had an affect on redox cycle stability as a good stabilizer for forming hydrogen by the steam-iron process.