• Journal of Korea Entertainment Industry Association
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• v.15 no.8
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• pp.269-278
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• 2021

This study was conducted to develop a learning competency scales customized for learning programs conducted by Center for Teaching & Learning at A University. To achieve this purpose, a preliminary study was set up, which consists of three competency groups (basic competency, intensity competency, application competency) and 13 learning competency factors through a review of previous studies. In order to verify the reliability and validity of the provisional learning competency scales, an online survey was conducted on A university students in September 2020, The collected questionnaire data were organized and exploratory factor analysis and confirmatory factor analysis were conducted. As a result of exploratory factor analysis, 13 learning competency was reduced to 10 as the three competency groups were maintained. As a result of the confirmatory factor analysis, the model was found to be good, Also, as a result of analyzing the reliability of the confirmed learning competency factors, all 10 factors showed a good level of .7 or more. The learning competency scales developed through this study can be used as basic data for performance evaluation and development of new programs of CTL learning program.

• Journal of Bio-Environment Control
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• v.31 no.4
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• pp.261-269
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• 2022

This study was carried out to predict fruit surface temperature (FST) causing sunburn symptoms and assess the correlation between solar radiation and FST in satusma mandarin (Citrus unshiu Marc. 'Iwasaki'). And to reduce sunburn when ambient temperature was at 31℃, sprinkler system was repeated spraying every at 5 minutes of 30 minutes intervals and 1% calcium carbonate and 4% kaolin solution applied on citrus tree three times to investigate quality and sunburn of fruits. It showed highly significant positive correlation between FST and solar radiation (R = 0.788, p < 0.01), The FST increased up to 16℃ than ambient temperature at daytime. To estimate FST, a linear model y = 0.099 × (air temperature) + 0.018 × (solar radiation) + 20.779 (R = 0.687, p < 0.01) was derived. The canopy temperature of citrus trees was 5.1℃ lower in sprinkler system than in control. The incidence of sunburn showed at 2.1% in sprinkler system twice lower than in control and there was different significance. Fruit quality was similar between treatments. In conclusion, sunburn can be reduced by reflecting sunlight or downing of FST through sprinkler system.

• Journal of Life Science
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• v.32 no.5
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• pp.355-361
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• 2022

Melanin pigments are the main cause of skin color. They are produced in melanocytes and then transferred to keratinocytes, which eventually gives the skin surface a variety of colors. Although many skin-lightening or depigmenting agents have been developed, the demand for materials to reduce pig- mentation is still increasing. Here, we tried to find materials for skin-lightening or depigmentation using natural compounds and found that mistletoe (Viscum album var. coloratum) extracts (ME) had an inhibitory effect on tyrosinase activity. As a result, ME significantly reduced pigmentation in human primary melanocytes. In addition, a promoter reporter assay revealed that ME inhibited the transcription of microphthalmia-associated transcription factor (MITF), melanophilin (MLPH), tyrosinase-related protein-2 (TRP-2), and tyrosinase (TYR) genes in HM3KO melanoma cells. In addition, ME decreased the protein level for pigmentation-related molecules, such as TYR and TRP-1. Furthermore, it markedly inhibited the melanogenesis of zebrafish embryos, an in vivo evaluation model for pigmentation. To elucidate the action mechanism of ME, we investigated its effects on intracellular signaling. Eventually, the ME dramatically decreased the phosphorylation of the cAMP responsive element binding protein (CREB), AKT, and ERK. The data suggest that ME may inhibit the melanogenesis pathway by regulating the signaling pathway related to pigmentation. Taken together, these data propose that ME can be developed as a depigmenting or skin-lightening agent.

• Nutrition Research and Practice
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• v.16 no.5
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• pp.589-603
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• 2022

BACKGROUND/OBJECTIVES: Previous studies have reported that protein supplementation contributes to the attenuation of inflammation. Serious trauma such as burn injury usually results in the excessive release of inflammatory factors and organs dysfunction. However, a few reports continued to focus on the function of protein ingestion in regulating burn-induced inflammation and organ dysfunction. MATERIALS/METHODS: This study established the rat model of 30% total body surface area burn injury, and evaluated the function of blended protein (mixture of whey and soybean proteins). Blood routine examination, inflammatory factors, blood biochemistry, and immunohistochemical assays were employed to analyze the samples from different treatment groups. RESULTS: Our results indicated a decrease in the numbers of white blood cells, monocytes, and neutrophils in the burn injury group administered with the blended protein nutritional support (Burn+BP), as compared to the burn injury group administered normal saline supplementation (Burn+S). Expressions of the pro-inflammatory factors (tumor necrosis factor-α and interleukin-6 [IL-6]) and chemokines (macrophage chemoattractant protein-1, regulated upon activation normal T cell expressed and secreted factor, and C-C motif chemokine 11) were dramatically decreased, whereas anti-inflammatory factors (IL-4, IL-10, and IL-13) were significantly increased in the Burn+BP group. Kidney function related markers blood urea nitrogen and serum creatinine, and the liver function related markers alanine transaminase, aspartate aminotransferase, alkaline phosphatase, and lactate dehydrogenase were remarkably reduced, whereas albumin levels were elevated in the Burn+BP group as compared to levels obtained in the Burn+S group. Furthermore, inflammatory cells infiltration of the kidney and liver was also attenuated after burn injury administered with blended protein supplementation. CONCLUSIONS: In summary, nutritional support with blended proteins dramatically attenuates the burn-induced inflammatory reaction and protects organ functions. We believe this is a new insight into a potential therapeutic strategy for nutritional support of burn patients.

• The Korean Journal of Physiology and Pharmacology
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• v.26 no.5
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• pp.335-345
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• 2022

Pyroptosis is an inflammatory form of programmed cell death that is linked with invading intracellular pathogens. Cardiac pyroptosis has a significant role in coronary microembolization (CME), thus causing myocardial injury. Tanshinone IIA (Tan IIA) has powerful cardioprotective effects. Hence, this study aimed to identify the effect of Tan IIA on CME and its underlying mechanism. Forty Sprague-Dawley (SD) rats were randomly grouped into sham, CME, CME + low-dose Tan IIA, and CME + high-dose Tan IIA groups. Except for the sham group, polyethylene microspheres (42 ㎛) were injected to establish the CME model. The Tan-L and Tan-H groups received intraperitoneal Tan IIA for 7 days before CME. After CME, cardiac function, myocardial histopathology, and serum myocardial injury markers were assessed. The expression of pyroptosis-associated molecules and TLR4/MyD88/NF-κB/NLRP3 cascade was evaluated by qRT-PCR, Western blotting, ELISA, and IHC. Relative to the sham group, CME group's cardiac functions were significantly reduced, with a high level of serum myocardial injury markers, and microinfarct area. Also, the levels of caspase-1 p20, GSDMD-N, IL-18, IL-1β, TLR4, MyD88, p-NF-κB p65, NLRP3, and ASC expression were increased. Relative to the CME group, the Tan-H and Tan-L groups had considerably improved cardiac functions, with a considerably low level of serum myocardial injury markers and microinfarct area. Tan IIA can reduce the levels of pyroptosis-associated mRNA and protein, which may be caused by inhibiting TLR4/MyD88/NF-κB/NLRP3 cascade. In conclusion, Tanshinone IIA can suppress cardiomyocyte pyroptosis probably through modulating the TLR4/MyD88/NF-κB/NLRP3 cascade, lowering cardiac dysfunction, and myocardial damage.

• The Journal of the Korea institute of electronic communication sciences
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• v.17 no.4
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• pp.649-662
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• 2022

As information security(IS) is recognized as an organization's core value, organizations are making efforts to adopt strict IS policies and technologies. However, strict IS policies can cause negative behavior for employees of organizations who need to apply IS to their work. This study confirms that IS can express the role stress of employees, and suggests a way to mitigate the IS role stress. Specifically, we confirm that organization justice and individual social identity can reduce IS role stress, which reduces IS voice behavior. In the study, we surveyed workers of organizations that applied IS policies to their work and obtained 318 samples. Also, we tested the hypothesis by applying the structural equation model. As a result, IS organization justice increased IS voice behavior through social identity and partially reduced IS voice behavior by mitigating IS role stress. In addition, social identity moderated the relationship between IS role stress and IS voice behavior. This study suggests strategies for achieving internal IS goals by suggesting conditions for mitigating IS role stress from an organizational and individual perspective.

• Geophysics and Geophysical Exploration
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• v.25 no.3
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• pp.129-139
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• 2022

Analog-based streamers for ultra-high-resolution seismic surveys are capable of additional noise ingress in water, but the specifications cannot be expanded through interconnections. Foreign-produced digital streamers have been introduced and used primarily at domestic research institutes; however, the cost is high and smooth maintenance is challenging. This study investigates the localization of ultra-high-resolution digital streamers capable of high-resolution imaging of a geological structure. A digital streamer capable of 24-bit, 10 kHz digital sampling of up to 64 channel data was developed through research and development. Various quantitative specifications of the system were designed and developed close to the benchmark model, Geometrics' GeoEel streamer, and the number of modules that make up the system was drastically reduced, reducing development costs and making it easier to use. The field applicability of the developed streamer system was evaluated in an in situ experiment conducted in the waters around the Port of Yeong-il Bay in Pohang in April 2022.

• Journal of Korean Medicine Rehabilitation
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• v.32 no.4
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• pp.1-8
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• 2022

Objectives This study is to investigate the effects and mechanisms of Gastrodia elata extract (GEE) on the high-fat diet-induced obesity model. Methods C57BL/6 mice were randomly assigned into 5 groups (n=10). Control group was fed normal diet (ND). Obesity group was fed 60% high fat diet (HFD). The other three groups were fed HFD with 100, 200, 500 mg/kg GEE. After five weeks, body weight, liver and epididymal fat weight, triglyceride concentration in liver and serum, sterol regulatory element-binding protein-1 (SREBP-1), acetyl-CoA carboxylase (ACC), fatty acid synthase, peroxisome proliferator-activated receptor 𝛾 (PPAR-𝛾), CCAAT/enhancer binding protein 𝛼 (C/EBP-𝛼) expression level, insulin concentration in serum were measured. Results The GEE (100, 200, and 500 mg/kg)-treated animals exhibited substantial decreases in body mass, liver weight and epididymal white adipose tissue collate to the HFD-fed group. GEE treatment also reduced hepatic and serum triglyceride level. Furthermore, GEE treatment significantly inhibited adipogenesis in the GEE group by reducing the protein expression of SREBP-1, ACC and the messenger RNA expression of PPAR𝛾, C/EBP-𝛼, which are adipocyte differentiation-related genes. Conclusions These research outcomes recommend that GEE is possibly valuable for the prevention of HFD-induced obesity via modification of various pathways related with adipogenesis and adipocyte differentiation.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.35 no.3
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• pp.273-281
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• 1990

Two rice varieties, Samkangbyeo and Sangpungbyeo, were transplanted on 1/2000a pots at 6 different dates beginning on May 11 with 10 day interval in 1987 and at 4 different dates beginning on May 21 with 10 day interval in a paddy field at the Chungbuk Provincial Rural Development Administration. Dry matter distributions to stem and leaf sheath, leaves and ear at different growth stages were analyzed to provide basic informations neccessary for the development of dynamic growth model. Dry matter production was reduced as transplanting was delayed and the degree of reduction was greater at the transplanting later than June 1. Dry matter distribution to stem and leaf sheath was increased up to 60-70 days after transplanting with the maximum ratio between 60-70%, which were decreased to 37-43% in pots and 27-33% in field at the end of ripening stage. On the other hand, dry matter distribution to leaf blade was decreased from 40-50% at transplanting to 11-17% at harvesting. Ear dry matter distribution increased rapidly after heading and the distribution ratio was 42-49% in pots and 52-62% in field. Although regression equations to predict dry matter distribution to different parts of rice plant were satisfactory for individual experiment, the application to different experiment was not appropriate.

• Journal of the Society of Disaster Information
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• v.19 no.1
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• pp.161-172
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• 2023

Safety education delivered to construction workers in a lecture manner has limitations in concentration and immersion, so delivery power and interest are low. In order to improve unstable behavior through education and prevent safety accidents, it is necessary to change the paradigm to hands-on education. Purpose: Experiential safety education aims to contribute to preventing accidents for construction workers by quickly recognizing risks, improving emergency response skills, and verifying the effectiveness of pre- and post-learning. Method: Based on a survey of workers who experienced the same work environment as the actual construction site, an opinion survey on the pre- and post-safety experience education and a variable measurement tool were planned, and a research hypothesis was established. Results: The Bayesian theory and MC simulation analysis were used to analyze the structural equation model, and the change in construction worker behavior was confirmed through the intended safety (A), non-experiential education in the sub-area of anxiety (B), average, standard deviation, and minimum and maximum values. Conclusion: The effect of education and industrial accidents are reduced only when construction workers are motivated to participate.