• International Journal of Computer Science & Network Security
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• v.22 no.6
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• pp.374-381
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• 2022

The article identifies and theoretically substantiates the trends of national resilience in the context of establishing the security of the country and its civilizational subjectivity. The strategy of development of the pedagogical university in the conditions of European integration into the European educational and scientific space based on certain characterological features of the personality of the volunteer in the context of allocation of personal resilience is developed. The analysis of both external and internal challenges and threats to the civilization of the country needs to be understood in the context of economic, socio-political, legal, military-political, spiritual-cultural, educational-scientific and network-information resilience. The concepts of "national resilience" and "national security" are quite close - at first glance, even identical. However, a deeper understanding clarifies the differences: national security is a state of protection of the country identity and its very existence, the realization of its national interests. In turn, resilience is a fairly effective strategy and a fundamental guarantee of national security. At the same time, it is extremely important to understand that both national security as a state and national resilience as a strategy are only means of achieving and developing a strong and humanistic civilizational subjectivity of the country. After all, such subjectivity opens for citizens the opportunity for development, dignified self-realization and a proper life. The restructuring of the volunteer's motivational sphere is due to the dominance of such leading motives, which are focused mainly on maintaining and restoring health, which leads to distorted meaningful life goals: isolation, alienation, passivity, inertia, reduced activity, limited communication, etc. The characteristics of relatively stable human behavior include several primary and secondary properties. The primary (relevant) properties include patience, trust, hope, faith, confidence, determination, perseverance, and love; the secondary - punctuality, neatness, obedience, honesty, loyalty, justice, diligence, thrift, accuracy, conscientiousness, obligation, etc. The restructuring of the volunteer's motivational sphere is due to the dominance of such leading motives, which are focused mainly on maintaining and restoring health, which leads to distorted meaningful life goals: isolation, alienation, passivity, inertia, reduced activity, limited communication, etc. The characteristics of relatively stable human behavior include several primary and secondary properties. The primary (relevant) properties include patience, trust, hope, faith, confidence, determination, perseverance, and love; the secondary - punctuality, neatness, obedience, honesty, loyalty, justice, diligence, thrift, accuracy, conscientiousness, obligation, etc. The use of information and communication technologies in volunteering will contribute to the formation of resilience traits in the structure of personality formation. Directly to the personal traits of resilience should be included methodological competencies, which include methodological knowledge, skills and abilities (ability to define ultimate and intermediate goals, plan, conduct and analyze knowledge, establish and implement interdisciplinary links with disciplines of medical-psychological-pedagogical cycles, etc.). All these competencies form the professional resilience of the volunteer.

• International Journal of Oncology
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• v.56 no.1
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• pp.368-378
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• 2020

Meridianin C is a marine natural product with anticancer activity. Several meridianin C derivatives (compounds 7a-j) were recently synthesized, and their inhibitory effects on pro-viral integration site for Moloney murine leukemia virus (PIM) kinases, as well as their antiproliferative effects on human leukemia cells, were reported. However, the anti-leukemic effects and mechanisms of action of meridianin C and its derivatives remain largely unknown. The aim of the present study was to investigate the effects of meridianin C and its derivatives on MV4-11 human acute myeloid leukemia cell growth. The parent compound meridianin C did not markedly affect the viability and survival of MV4-11 cells. By contrast, MV4-11 cell viability and survival were reduced by meridianin C derivatives, with compound 7a achieving the most prominent reduction. Compound 7a notably inhibited the expression and activity of PIM kinases, as evidenced by reduced B-cell lymphoma-2 (Bcl-2)-associated death promoter phosphorylation at Ser112. However, meridianin C also suppressed PIM kinase expression and activity, and the pan-PIM kinase inhibitor AZD1208 only slightly suppressed the survival of MV4-11 cells. Thus, the anti-survival effect of compound 7a on MV4-11 cells was unrelated to PIM kinase inhibition. Moreover, compound 7a induced apoptosis, caspase-9 and -3 activation and poly(ADP-ribose) polymerase (PARP) cleavage, but did not affect death receptor (DR)-4 or DR-5 expression in MV4-11 cells. Compound 7a also induced the generation of cleaved Bcl-2, and the downregulation of myeloid cell leukemia (Mcl)-1 and X-linked inhibitor of apoptosis (XIAP) in MV4-11 cells. Furthermore, compound 7a increased eukaryotic initiation factor (eIF)-2α phosphorylation and decreased S6 phosphorylation, whereas GRP-78 expression was unaffected. Importantly, treatment with a pan-caspase inhibitor (z-VAD-fmk) significantly attenuated compound 7a-induced apoptosis, caspase-9 and -3 activation, PARP cleavage, generation of cleaved Bcl-2 and downregulation of Mcl-1 and XIAP in MV4-11 cells. Collectively, these findings demonstrated the strong anti-survival and pro-apoptotic effects of compound 7a on MV4-11 cells through regulation of caspase-9 and -3, Bcl-2, Mcl-1, XIAP, eIF-2α and S6 molecules.

• Journal of the Korean Institute of Landscape Architecture
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• v.40 no.5
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• pp.51-62
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• 2012

Geumho-dong, Seoul, a redeveloped residential area, is located in the foothills of Mt. Eungbong. The geographical undulation, the composition of a large apartment complex, and the partial implementation of the redevelopment project have caused the severe physical and social disconnections in this area. In order to recover functioning in the disconnected community, this study pays attention to the regeneration of the open spaces as an everyday place and in the form a network system among those open spaces. Various types of the open spaces are classified into points or faces, 'bases' and linear 'paths' analyze the network status. More than half of the open space have connecting-distance of 500m or more. Furthermore, many areas are not even included in the service-area of the open spaces. Analysis of the connectivity and integration value using the axial map has carried out to check weak linkages and to choose the sections where additional bases are required. In addition, to improve the quality of the bases and the paths, a field investigation is conducted and problems are diagnosed. The network planning of the open spaces in Geumho-dong is established, ensuring the quality and quantity of bases and paths. The plan includes the construction of an additional major base in the central area and six secondary bases in other parts, and comes up with ways to improve the environment of underdeveloped secondary bases. In the neighborhood parks at Mt. Daehyun areas, the major path are added, and the environment of the paths is improved in certain areas. Because of the network planning, the connecting-distances between bases are reduced significantly, the connectivity and integration value of the area are increased, and the service areas of the open spaces cover the whole area properly. Although this study has some limitations such as the needs for the legal and institutional supports and difficulties of a quantitative indexing process, its significance lies in the suggestion of a more reasonable and practical plan for the overall network system by defining complex types of open spaces simply and clearly and by examining the organic relationships quantitatively and qualitatively.

• The Korean Journal of Nuclear Medicine
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• v.37 no.5
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• pp.288-300
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• 2003

Purpose: To obtain regional blood flow and tissue-blood partition coefficient with time-activity curves from ${H_2}^{15}O$ PET, fitting of some parameters in the Kety model is conventionally accomplished by nonlinear least squares (NLS) analysis. However, NLS requires considerable compuation time then is impractical for pixel-by-pixel analysis to generate parametric images of these parameters. In this study, we investigated several fast parameter estimation methods for the parametric image generation and compared their statistical reliability and computational efficiency. Materials and Methods: These methods included linear least squres (LLS), linear weighted least squares (LWLS), linear generalized least squares (GLS), linear generalized weighted least squares (GWLS), weighted Integration (WI), and model-based clustering method (CAKS). ${H_2}^{15}O$ dynamic brain PET with Poisson noise component was simulated using numerical Zubal brain phantom. Error and bias in the estimation of rCBF and partition coefficient, and computation time in various noise environments was estimated and compared. In audition, parametric images from ${H_2}^{15}O$ dynamic brain PET data peformed on 16 healthy volunteers under various physiological conditions was compared to examine the utility of these methods for real human data. Results: These fast algorithms produced parametric images with similar image qualify and statistical reliability. When CAKS and LLS methods were used combinedly, computation time was significantly reduced and less than 30 seconds for $128{\times}128{\times}46$ images on Pentium III processor. Conclusion: Parametric images of rCBF and partition coefficient with good statistical properties can be generated with short computation time which is acceptable in clinical situation.

• Economic and Environmental Geology
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• v.48 no.6
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• pp.451-465
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• 2015

The free-air anomalies are computed using a data set from various types of gravity measurements in the Korean Peninsula area. The gravity values extracted from the Earth Gravitational Model 2008 are used in the surrounding region. The upward continuation technique suggested by Dragomir is used in the computation of the external free-air anomalies at various altitudes. The integration radius 10 times the altitude is used in order to keep the accuracy of results and computational resources. The direct geodesic formula developed by Bowring is employed in integration. At the 1-km altitude, the free-air anomalies vary from -41.315 to 189.327 mgal with the standard deviation of 22.612 mgal. At the 3-km altitude, they vary from -36.478 to 156.209 mgal with the standard deviation of 20.641 mgal. At the 1,000-km altitude, they vary from 3.170 to 5.864 mgal with the standard deviation of 0.670 mgal. The predicted free-air anomalies at 3-km altitude are compared to the published free-air anomalies reduced from the airborne gravity measurements at the same altitude. The rms difference is 3.88 mgal. Considering the reported 2.21-mgal airborne gravity cross-over accuracy, this rms difference is not serious. Possible causes in the difference appear to be external free-air anomaly simulation errors in this work and/or the gravity reduction errors of the other. The external gravity field is predicted by adding the external free-air anomaly to the normal gravity computed using the closed form formula for the gravity above and below the surface of the ellipsoid. The predicted external gravity field in this work is expected to reasonably present the real external gravity field. This work seems to be the first structured research on the external free-air anomaly in the Korean Peninsula area, and the external gravity field can be used to improve the accuracy of the inertial navigation system.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.8
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• pp.39-48
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• 2016

In this paper, we propose thermal resistance compact model of FinFET structure that has hexagon shaped source/drain. The heating effect and thermal properties were increased by reduced size of the device, and thermal resistance is an important factor to analyze the effect and the properties. The heat source and each contact that is moved heat out were set up in transistor, and domain is divided by the heat source and the four parts of contacts : source, drain, gate, substrate. Each contact thermal resistance model is subdivided as a easily interpretable structure by analyzing the temperature and heat flow of the TCAD simulation results. The domains are modeled based on an integration or conformal mapping method through the structure parameters according to its structure. First modeled by analyzing the thermal resistance to a single fin, and applying the change in the parameter of the channel increases to improve the accuracy of the thermal resistance model of the multi-fin/ finger. The proposed thermal resistance model was compared to the thermal resistance by analyzing results of the 3D Technology CAD simulations, and the proposed total thermal resistance model has an error of 3 % less in single and multi-finl. The proposed thermal resistance model can predict the thermal resistance due to the increase of the fin / finger, and the circuit characteristics can be improved by calculating the self-heating effect and thermal characterization.

• Wind and Structures
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• v.10 no.4
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• pp.367-382
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• 2007

A nonlinear numerical method was developed to assess the stability of suspension bridge catwalks under a wind load. A section model wind tunnel test was used to obtain a catwalk's aerostatic coefficients, from which the displacement-dependent wind loads were subsequently derived. The stability of a suspension bridge catwalk was analyzed on the basis of the geometric nonlinear behavior of the structure. In addition, a full model test was conducted on the catwalk, which spanned 960 m. A comparison of the displacement values between the test and the numerical simulation shows that a numerical method based on a section model test can be used to effectively and accurately evaluate the stability of a catwalk. A case study features the stability of the catwalk of the Runyang Yangtze suspension bridge, the main span of which is 1490 m. Wind can generally attack the structure from any direction. Whenever the wind comes at a yaw angle, there are six wind load components that act on the catwalk. If the yaw angle is equal to zero, the wind is normal to the catwalk (called normal wind) and the six load components are reduced to three components. Three aerostatic coefficients of the catwalk can be obtained through a section model test with traditional test equipment. However, six aerostatic coefficients of the catwalk must be acquired with the aid of special section model test equipment. A nonlinear numerical method was used study the stability of a catwalk under a yaw wind, while taking into account the six components of the displacement-dependent wind load and the geometric nonlinearity of the catwalk. The results show that when wind attacks with a slight yaw angle, the critical velocity that induces static instability of the catwalk may be lower than the critical velocity of normal wind. However, as the yaw angle of the wind becomes larger, the critical velocity increases. In the atmospheric boundary layer, the wind is turbulent and the velocity history is a random time history. The effects of turbulent wind on the stability of a catwalk are also assessed. The wind velocity fields are regarded as stationary Gaussian stochastic processes, which can be simulated by a spectral representation method. A nonlinear finite-element model set forepart and the Newmark integration method was used to calculate the wind-induced buffeting responses. The results confirm that the turbulent character of wind has little influence on the stability of the catwalk.

• Journal of the Korean Solar Energy Society
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• v.36 no.6
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• pp.25-35
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• 2016

In this study, the evaluation of the dynamic behavior and thermal performance of the "Façade integrated Natural circulation Solar Water Heating System" installed in the residential house was carried out. Experimental tests were performed during the all year around in the rural houses of $166m^2$ in size. Facade integrated solar collector of $5m^2$ were installed on the south-facing. Electrical heater of 1 kW capacity as an auxiliary heater was installed at the upper part of the heat storage tank. The analyzing results are as follows. (1) Monthly average solar fraction was 51 to 87% and yearly average value is 64%. (2) Hot water supply temperature in December which has the lowest solar altitude is 37 to $76^{\circ}C$. The highest working fluid temperature of solar collector in this period was below $84^{\circ}C$. The temperature difference of working fluid between the collector inlet and outlet has been shown to be around 9 to $26^{\circ}C$. (3) Overheating which is one of the biggest problems during summer did not appear at all, but rather had hot water supply temperature is rather low as $30{\sim}47^{\circ}C$ in summer than winter, which is supplied by a small solar load. The solar collecting temperature has been shown to maintain below $55^{\circ}C$. (5) The thermal performance of Facade integrated solar collector can be increase due to the reduction of heat loss to the back of the collector wall integration of the collector is reduced. As a conclusion, Facade integrated natural circulation type Solar Water Heating System is a well-functioning without any pumps or controllers, and it was found that the disadvantages of conventional solar water heaters, hot water or hot water system can be greatly improved.

• Journal of KIISE:Information Networking
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• v.34 no.6
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• pp.514-524
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• 2007

Recent advances in the speed of multi-rate wireless local area networks (WLANs) and the proliferation of WLAN devices have made rate adaptive, opportunistic scheduling critical for throughput optimization. As WLAN traffic evolves to be more symmetric due to the emerging new applications such as VoWLAN, collaborative download, and peer-to-peer file sharing, opportunistic scheduling at the downlink becomes insufficient for optimized utilization of the single shared wireless channel. However, opportunistic scheduling on the uplink of a WLAN is challenging because wireless channel condition is dynamic and asymmetric. Each transmitting client has to probe the access point to maintain the updated channel conditions at the access point. Moreover, the scheduling decisions must be coordinated at all clients for consistency. This paper presents JUDS, a joint uplink/downlink opportunistic scheduling for WLANs. Through synergistic integration of both the uplink and the downlink scheduling, JUDS maximizes channel diversity at significantly reduced scheduling overhead. It also enforces fair channel sharing between the downlink and uplink traffic. Through extensive QualNet simulations, we show that JUDS improves the overall throughput by up to 127% and achieves close-to-perfect fairness between uplink and downlink traffic.

• Journal of the Korea Convergence Society
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• v.9 no.7
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• pp.241-249
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• 2018

The military purpose vehicles are developed by using the platform of civil vehicles according to the commercial vehicle expansion plan and military supplied product commercialization policy. But the information related to the military purpose vehicle which adopts the same platform with the civil vehicle is forced to be exposed because its information is revealed by containing into the maintenance manual and electric circuit diagram. Especially, the information disclosure should be blocked by reviewing the application of technology protection because the military vehicle becomes combating purposed mixed equipment when the missile and radar are mounted. The mixed equipment means the one configured with more than 2 types of equipment, and it is categorized into the main and sub equipment. This study was performed to derive the problems in Korean system for vehicle part test evaluation on the mixed equipment and the defense industry technology protection system, and to derive the methods for improving through interviews with the specialists. The conflicts between the civil laws and army regulation were reduced by adding a clause that the engine reflected with the newest emission gas standard should be mounted based on the time of force integration, and the commercialized military supplies were designated as element technology of defense industry technology in consideration of its roles and functions.