• Title/Summary/Keyword: Redistribution

Search Result 779, Processing Time 0.023 seconds

Expression of c-jun by X-ray According to Cell Growth State in CaSki Cell Line (CaSki 세포주에서 성장 상태에 따른 X-선에 의한 c-jun의 발현)

  • Jang, Seong-Sun;Park, Woo-Yoon
    • Radiation Oncology Journal
    • /
    • v.17 no.3
    • /
    • pp.223-229
    • /
    • 1999
  • Purpose : The expression pattern of c-jun by ionizing radiation according to cell growth state (exponential growth vs. stationary phase) and its relationship with cell cycle redistribution were investigated. Materials and Methods : The exponential growth phase (day 4) and stationary phase (day 9) cells were determined from cell growth curve according to the elapse of days in CaSki. The cells were irradiated using 6 MV X-ray with a dose of 2 Gy at a fixed dose rate of 3 Gy/min. Northern blot analysis was peformed with total cellular RNA and cell cycle distribution was analyzed using flow cytometry according to time-course after irradiation. Results : The maximum expression of c-jun occurred 1 hour after irradiation in both exponential growth and stationary phase cells. After then c-jun expression was elevated upto 6 hours in exponential growth phase cells, but the level decreased in stationary phase cells. Movements of cells from G0-G1 to S, G2-M phase after irradiation were higher in exponential growth phase than stationary phase. Conclusion : c-jun may be involved in the regulation of cellular proliferation according to the growth states after irradiation.

  • PDF

Investigating Remotely Sensed Precipitation from Different Sources and Their Nonlinear Responses in a Physically Based Hydrologic Model (다른 원격탐사 센서로 추출한 강우자료의 이질성과 이에 의한 비선형유출반응에 미치는 영향)

  • Oh, Nam-Sun;Lee, Khil-Ha;Kim, Sang-Jun
    • Journal of Korea Water Resources Association
    • /
    • v.39 no.10 s.171
    • /
    • pp.823-832
    • /
    • 2006
  • Precipitation is the most important component to the study of water and energy cycle in hydrology. In this study we investigate rainfall retrieval uncertainty from different sources of remotely sensed precipitation field and then probable error propagation in the simulation of hydrologic variables especially, runoff on different vegetation cover. Two remotely sensed rainfall retrievals (space-borne IR-only and ground radar rainfall) are explored and compared visually and statistically. Then, an offline Community Land Model (CLM) is forced with in situ meteorological data to simulate the amount of runoff and determine their impact on model predictions. A fundamental assumption made in this study is that CLM can adequately represent the physical land surface processes. Results show there are big differences between different sources of precipitation fields in terms of the magnitude and temporal variability. The study provides some intuitions on the uncertainty of hydrologic prediction via the interaction between the land surface and near atmosphere fluxes in the modelling approach. Eventually it will contribute to the understanding of water resources redistribution to the climate change in Korean Peninsula.

Collapse Capacity Evaluation of Steel Intermediate Moment Frames Using Incremental Dynamic Analysis (비선형 증분동적해석을 통한 철골 중간모멘트 골조의 붕괴성능 평가)

  • Shin, Dong-Hyeon;Kim, Hyung-Joon
    • Journal of the Korea institute for structural maintenance and inspection
    • /
    • v.18 no.2
    • /
    • pp.9-20
    • /
    • 2014
  • Steel intermediate moment frames (IMFs) have been generally used as seismic load resisting systems (SLRSs) of a building to provide resistances against strong ground shaking. However, most of low and mid-rise steel buildings in Korea were constructed during pre-seismic code era or before the introduction of well-organized current seismic codes. It has been recognized that the seismic performance of these steel IMFs is still questionable. In order to respond to such a question, this study quantitatively investigates the seismic capacities of steel IMFs. Prototype models are built according to the number of stories, the levels of elastic seismic design base shear and the ductilities of structural components. Also, the other prototype models employing hysteretic energy dissipating devices (HEDDs) are considered. The collapse mechanism and the seismic performance of the prototype models are then described based on the results obtained from nonlinear-static and incremental-dynamic analyses. The seismic performance of the prototype models is assessed from collapse margin ratio (CMR) and collapse probability. From the assessment, the prototype model representing new steel IMFs has enough seismic capacities while, the prototype models representing existing steel IMFs provide higher collapse probabilities. From the analytic results of the prototype models retrofitted with HEDDs, the HEDDs enhance the seismic performance and collapse capacity of the existing steel IMFs. This is due to the energy dissipating capacity of the HEDDs and the redistribution of plastic hinges.

Reversely Zoned Compositional Variations and their Origins of the Andong Pluton, Andong Batholith, Korea (안동심성암체의 역누대 초성변화와 그 성인)

  • 황상구;이보현
    • Economic and Environmental Geology
    • /
    • v.35 no.1
    • /
    • pp.75-95
    • /
    • 2002
  • The Andong pluton in the Andong Batholith is composed of comagmatic plutonic rocks, in which the lithofacies comprise hornblende biotite tonalite in the central paft biotite granodiorite in the marginal paft and porphyritic biotite granite at the topside (noJthea~tern paft) of the pluton. The pluton is petrographically and petrochemically zoned, having more mafic center than margin and topside. Distribution pallern of the lithofacies represents a reverse zoning in the pluton. Modal and chemical data in the pluton show progressive and gradual compositional variations from the centrer via the margin to the topside. Quartz and K-teldspar increase toward the topside of the pluton, whereas hornblende, biotite and color index increase toward the center. The bulk composition in the pluton is also reversely zoned, with high $Si0_2$ and $K_{2}O$ in the topside facies, and high MnO, CaO, $Ti0_2$, $Fe_{2}O_{3}$t, MgO and $P_{2}O_{5}$ in the central facies. The reverse zoning is also evident in higher Cr. V, Ni, Sc and Sr of the more mafic tonalite in the interior. The reversely zoned pluton results from remobilization (resurgence) of the lower more mafic compositional zone into the upper more felsic zones of the pluton modified by thennogravitational diffusion and fractional crystallization. In the initial stages of evolution, the pluton was a petrochemical system that fonned chemical compositional zonation with mafic tonalitic magma in the lower. granodioritic one in the middle and granitic one in the upper paft of the magma chamber. Periodic influxes of more mafic magma from the ba~e resulted in mingling of liquids and redistribution of minerals, and may have triggered the remobilil.ation of the lower compositional zone into the upper more felsic zones.

An Immune-Electron Microscopic Study of the Apoptotic Cell during Mouse Knee Joint Development (생쥐 무릎관절 공간 발생에 있어 아포프토시스 세포에 관한 면역전자현미경적 연구)

  • Chae, Hee-Sun;Kim, Kyung-Yong;Lee, Won-Bok;Lim, Hyoung-Soo;Hwang, Douk-Ho;Chang, Ka-Yong
    • Applied Microscopy
    • /
    • v.28 no.1
    • /
    • pp.107-119
    • /
    • 1998
  • This study was designed to investigate the appearence and the characteristics of the apoptotic cells and the process of the joint cavity formation in mouse knee joint. Fetal mouse knee joints from 15 to 19 days of gestation were used. Paraffin-embedded serial sections, stained with H & E for light microscopic observation, Epon 812 embedded thin sections for electron microscopic observation and Lowicryl HM 20 embedded thin sections for immune-electron microscopic observation were prepared. Monoclonal antibodies to $\beta-tubulin$ and polyclonal antibodies to tissue transglutaminase were used for immune-electron microscopic study. The results obtained were as follows. 1. At 15 days of gestation, blood vessels, which have invaded in the mesenchymal cells, were present in the synovium, to form the joint cavity in the future. 2. At 16 days of gestation, the joint cleft was first appeared and several RBCs were present in the joint cleft. The invasion of blood vessels into the joint cleft was continuing, and apoptotic cells were present in the inner cell layer, adjacent to the joint cleft. Necrotic cells were also present in the outer cell layer; they were present 18 days of gestation, but apoptotic cells did not appear after 17 days of gestation. 3. In the apoptotic cells, transglutaminase were localized around vacuoles and the marginal site of the cytoplasm. 4. In the apoptotic cells, tubulin was around the endoplasmic reticulum and the marginal site of the cytoplasm. In the late stage of apoptotic cells, tubulin was localized diffusely in the cytoplasm. Tubulin was also strongly labeled around in the cytoplasm of the neighboring cell at which the apoptotic body was phagocytosed. Tubulin labeled particles were apparently increased in the seperated apoptotic bodies. On the basis of the above findings, it is proposed that during the development of the mouse knee joint, blood vessel invasion first occurs and then apoptosis and cell necrosis follow it. In the apoptotic cell, present in the synovium of the developing knee joint of the mouse. it is suggested that the redistribution of tubulin is associated with apoptotic process. And transglutaminase overexpressed in the apoptotic cell.

  • PDF

Case Study on Fracture Type of Wooden Crib Wall (목재 Crib wall의 파괴유형에 대한 사례연구)

  • Shin, Changgun;Paik, Moonyeol;Hong, Cheolhwa;Bae, Wooseok
    • Journal of the Korean GEO-environmental Society
    • /
    • v.14 no.7
    • /
    • pp.39-50
    • /
    • 2013
  • Crib wall is one of the segmental grid retaining walls using headers and stretchers to establish the framework of the wall. In this method, grids formed by the intersection of headers and stretchers are generally filled with the gravel to maintain the weight of the wall. Therefore, the construction can be carried out with higher speed and much economically when compared with the concrete retaining wall. Furthermore, it has high drain capacity, and environmentally friendly aspects also have been pointed out because the possibility of the planting at the front of the wall. However, in the wooden crib wall method, the relative movement between the individual headers and stretchers was generally recognized, and stress redistribution in the gravel filling was also observed when subjected to the external loading and self-weight of filling. In this study, it was analyzed fracture types and causes of wooden crib wall through detailed investigation and analysis of a large crib wall construction site. As a results, it occurred the damage in the members of 5.7% in a total of 2,315 locations and the damage of header occurred in the members of a header 80.2%. The 65.7% of the damaged header are concentrated in the lower part of crib wall. Therefore, it was analyzed the differences of fracture types and causes of wooden crib wall depending on the installation position and the kinds of members. It is considered basically the members of various forms of distortion and the grain affecting.

Biogeochemistry of Metal and Nonmetal Elements in the Surface Sediment of the Gamak Bay (가막간 표층퇴적물 중의 금속 및 비금속 원소의 생지화확적 분포특성)

  • Kim, Pyoung-Joong;Shon, Sang-Gyu;Park, Soung-Yun;Kim, Sang-Soo;Jang, Su-Jeong;Jeon, Sang-Baek;Ju, Jae-Sik
    • Journal of the Korean Society of Marine Environment & Safety
    • /
    • v.18 no.2
    • /
    • pp.67-83
    • /
    • 2012
  • In order to evaluate die geochemical characteristics of sediment in a semi-enclosed bay used as shellfish and fish farming area, the concentrations of metallic(V, Cr, Mn, Fe, Co. Ni, Cu, Zn, Ag, Cd, Hg, Ph, As) and non-metallic(P, Se) elements and uranium were measured in the surface sediment samples collected from 19 stations of Gamak Bay in April 2010. Metal contamination status in the sediments were also evaluated using the sediment quality guidelines(SQGs) proposed by the National Oceanic and Atmospheric Administration(NOAA) and the enrichment factor(EF). The concentrations of elements in sediment were mainly controlled by quartz-dilution effect(V, Cr, Fe, Co and Ni), the dilution effect of organic matter(Cd and U), and metal redistribution by the decomposition of organic matter(Mn, Ag, As, and Se). The concentrations of metals, except As and Ni, in sediments from all sampling stations were lower than ERL values of NOAA. Conclusively, the surface sediment of Gamak Bay was slightly polluted with Ni, Ag, Cd, and Cd but was not polluted with other elements on the basis of EF results. Our results suggest that the surface sediment in Gamak Bay is not polluted by metallic elements.

Evaluation on Rear Fracture Reduction and Crack Properties of Cement Composites with High-Velocity Projectile Impact by Fiber Types (섬유 종류에 따른 시멘트복합체의 고속 비상체 충격에 대한 배면파괴저감 및 균열특성 평가)

  • Han, Sang-Hyu;Kim, Gyu-Yong;Kim, Hong-Seop;Kim, Jung-Hyun;Nam, Jeong-Soo
    • Journal of the Korea Concrete Institute
    • /
    • v.27 no.2
    • /
    • pp.157-167
    • /
    • 2015
  • Cement composites subjected to high-velocity projectile shows local failure and it can be suppressed by improvement of flexural toughness with reinforcement of fiber. Therefore, researches on impact resistance performance of cement composites are in progress and a number of types of fiber reinforcement are being developed. Since bonding properties of fiber with matrix, specific surface area and numbers of fiber are different by fiber reinforcement type, mechanical properties of fiber reinforced cement composites and improvement of impact resistance performance need to be considered. In this study, improvement of flexural toughness and failure reduction effect by impact of high-velocity projectile have been evaluated according to fiber type by mixing steel fiber, polyamide, nylon and polyethylene which are have different shape and mechanical properties. As results, flexural toughness was improved by redistribution of stress and crack prevention with bridge effect of reinforced fibers, and scabbing by high-velocity impact was suppressed. Since it is possible to decrease scabbing limit thickness from impact energy, thickness can be thinner when it is applied to protection. Scabbing of steel fiber reinforced cement composites was occurred and it was observed that desquamation of partial fragment was suppressed by adhesion between fiber and matrix. Scabbing by high-velocity impact of synthetic fiber reinforced cement composites was decreased by microcrack, impact wave neutralization and energy dispersion with a large number of fibers.

A Practical Attack on In-Vehicle Network Using Repacked Android Applications (커넥티드 카 환경에서 안드로이드 앱 리패키징을 이용한 자동차 강제 제어 공격)

  • Lee, Jung Ho;Woo, Samuel;Lee, Se Young;Lee, Dong Hoon
    • Journal of the Korea Institute of Information Security & Cryptology
    • /
    • v.26 no.3
    • /
    • pp.679-691
    • /
    • 2016
  • As vehicle started to contain many different communication devices, collecting external information became possible in IoT environment. In such environment, remotely controling vehicle is possible when vehicle information is obtained by looking in to vehicle network through smart device. However, android based smart device applications are vulnerable to malicious modulation and redistribution. Modulated android application can lead to vehicle information disclosure that could bring about vehicle control accident which becomes threat to drivers. furthermore, since vehicles today does not contain security methods to protect it, they are very vulnerable to security threats which can cause serious damage to users and properties. In this paper, many different vehicle management android applications that are sold in Google Play has been analyzed. With this information, possible threats that could happen in vehicle management applications are being analysed to prove the risks. the experiment is done on actual vehicle to prove the risks. Also, access control method to protect the vehicle against malicious actions that could happen through external network in IoT environment is suggested in the paper.

Multi-Cultural Space and Glocal Ethics : From Cultural Space of Transnational Capitalism to Space of Recognition Struggle (다문화공간과 지구-지방적 윤리 : 초국적 자본주의의 문화공간에서 인정투쟁의 공간으로)

  • Choi, Byung-Doo
    • Journal of the Korean association of regional geographers
    • /
    • v.15 no.5
    • /
    • pp.635-654
    • /
    • 2009
  • Recently, concepts of multicultural society and/or multiculturalism have been not only widely discussed across several disciplines, but also actively promoted in government's policy, as the in-flow of foreign immigrants has increased rapidly. This paper suggests the term 'multicultural space' instead of multicultural society in a sense that both international migration of immigrants and their accommodation to a certain locality presuppose a spatial dimension. This paper also points out that the term multiculturalsim should be used very carefully, because this term includes a normative character implied in a sense of recognition of ethnic and cultural diversity and difference on the one hand, and an ideological one reflected on strategic policies of capital and the state on the other. On the basis of recognition of these problems, this paper tries to reformulate spatially the concept of muticultural society which has been supposed to be constructed due to rapidly increasing foreign immigrants, emphasizing some usefulness of multi-scalar approach. It then analyzes economic and political contexts of transnational migration, providing a criticism of multiculturalism as an ideological logic of capital and the state in transnational captialism. Finally it put a stress upon importance of struggle for spaces of recognition as a new glocal ethics in the age of post-globalization.

  • PDF