• 방송공학회논문지
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• 제15권6호
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• pp.731-741
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• 2010

본 논문에서는 30 MHz ~ 3000 MHz 대역에서 1 kW ERP에 대해 점-대-지역 전파특성 예측에 이용되는 ITU-R 권고 P.1546 전파 모델을 이용하여 DTV 수신기의 전계강도 예측을 위한 방법을 제안한다. DTV 수신기의 유도된 전계강도 수식과 권고에서 기술된 절차를 이용하여 수치계산을 통한 결과를 제시한다. 또한 산출된 결과의 적절성 검증을 위해 Okumura-Hata 모델과 비교하였으며, 수신 전계강도가 약 6.9 ~ 11.5 % 범위 내에 오차가 있음을 확인할 수 있었다. 제시된 방법은 DTV 수신지역의 전계강도 예측을 통한 송신된 신호의 품질 분석은 물론, 양호한 전파환경 구축을 위한 적절한 국소 선정을 제공한다. 또한 동일 대역의 주파수 공유를 위한 보호비 또는 이격 거리 분석에도 직접 활용이 가능하다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권6호
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• pp.2369-2373
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• 2015

Objective: To analyze efficacy of neoadjuvant chemotherapy for advanced ovarian cancer. Materials and Methods: A total of 107 patients with advanced ovarian cancer undergoing cytoreductive surgery were divided into a neoadjuvant chemotherapy group (n=61) and a primary debulking group (n=46) and retrospectively analyzed. Platinum-based adjuvant chemotherapy was applied to both groups after cytoreductive surgery ande overall and progression-free survival times were calculated. Results: No significant difference was observed in duration of hospitalization ($20.8{\pm}6.1$ vs. $20.2{\pm}5.4$ days, p>0.05). The operation time of neoadjuvant chemotherapy group was shorter than the initial surgery group ($3.1{\pm}0.7$ vs. $3.4{\pm}0.8$ h, p<0.05). There were no significant differences in median overall survival time between neoadjuvant chemotherapy group and surgery group (42 vs. 55 months, p>0.05). Similarly, there was no difference in median progression-free survival between neoadjuvant chemotherapy group and surgery group (16 vs. 17 months, p>0.05). The surgical residual tumor size demonstrated no significant difference between initial surgery and neoadjuvant chemotherapy groups (p>0.05). Multivariate analysis showed that more than 3 cycles of regimen with neoadjuvant chemotherapy was associated with more resistance to chemotherapy compared with patients without receiving neoadjuvant chemotherapy (OR: 5.962, 95%CI: 1.184-30.030, p<0.05). Conclusions:Neoadjuvant chemotherapy can shorten the operation time. However, it does not improve survival rates of advanced ovarian cancer patients.

• 상하수도학회지
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• 제23권5호
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• pp.655-667
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• 2009

An experimental study is performed on reducing the pollutants supplied by storm water through enhancing efficiency of SS from the detention storage tank where CSOs are kept temporarily before discharge to the receiving water system. SS removal efficiency is investigated in accordance with various conditions of the detention pond-such as its length, the existence of training wall, and the use of gravel filling. The removal efficiency is strongly affected by the detention pond's length until the critical falling distance of the suspended solids is reached. For cases where the tank has a length longer than this critical condition, the removal rate shows less sensitivity. To enhance the SS removal efficiency of tanks of shorter than the critical length, we studied alternative types of tank in which inside training walls are installed. The results showed improvement of 14 to 37% in removal efficiency in 2hours detention(2 training walls). The important factor in achieving a high SS removal rate is ensuring the critical length of the detention pond, but for the cases where the basin length cannot be guaranteed, baffles or a gravel filling scheme may be introduced to attain considerable efficiency. The results of studying and comparing different storage tank conditions show that, in terms of elimination efficiency, a storage tank with gravel filling and training walls > a storage tank with gravel filling > a storage tank with training walls > an empty tank. The experimental results should contribute to development of related further research, by empirically verifying the already assumed importance of critical falling distance, training walls, and gravel filling schemes.

• Asian Pacific Journal of Cancer Prevention
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• 제16권2호
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• pp.775-781
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• 2015

Background: RB1 (retinoblastoma 1) was reportedly one of the major determinative factors for sensitivity to taxanes in previous studies. In this study, we investigated the influence of RB1 single nucleotide polymorphisms (SNPs) on the efficacy of platinum-taxane regimens in advanced NSCLC patients. Materials and Methods: 234 cases of patients with advanced NSCLC who were treated with first-line platinum-taxane agents were enrolled in this study. Genomic DNA was extracted from patients' peripheral blood samples using a QIAamp DNA Maxi Kit, and genotyped by iSelect HD Bead-Chip. Results: Regression analyses were conducted through the univariate and multivariate Cox proportional hazards model in the 234 patients. The results showed that of the eight RB1 tagSNPs, only rs4151510 was a positive predictive factor for the advanced NSCLC patients treated with platinum taxanes regimen. The patients with G/G genotype of RB rs4151510 had longer overall survival (OS) than the non-G/G genotype (p=0.018). The histology was also correlated with OS in the whole advanced NSCLC patients. Three tagSNPs of RB1, rs4151510, rs4151465, rs9568036 were significantly associated with OS in the advanced NSCLC patients with squamous cell histology using Kaplan-Meier overall survival analysis stratified by histology. Conclusions: RB1 genomic variants were correlated with the efficacy of platinum-taxanes regimen. RB rs4151510 is an independent factor of the prognosis of NSCLC patients receiving platinum-taxane chemotherapy.

• Asian Pacific Journal of Cancer Prevention
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• 제16권18호
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• pp.8265-8270
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• 2016

Purpose: A cost-utility analysis was performed to assess the cost-utility of neoadjuvant chemotherapy regimens containing doxorubicin and cyclophosphamide (AC) versus paclitaxel and gemcitabine (PG) for locally advanced breast cancer patients in Iran. Materials and Methods: This cross-sectional study in Namazi hospital in Shiraz, in the south of Iran covered 64 breast cancer patients. According to the random numbers, the patients were divided into two groups, 32 receiving AC and 32 PG. Costs were identified and measured from a community perspective. These items included medical and non-medical direct and indirect costs. In this study, a data collection form was used. To assess the utility of the two regimens, the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core30 (EORTC QLQ-C30) was applied. Using a decision tree, we calculated the expected costs and quality adjusted life years (QALYs) for both methods; also, the incremental cost-effectiveness ratio was assessed. Results: The results of the decision tree showed that in the AC arm, the expected cost was 39,170 US$ and the expected QALY was 3.39 and in the PG arm, the expected cost was 43,336 dollars and the expected QALY was 2.64. Sensitivity analysis showed the cost effectiveness of the AC and ICER=-5535 US$. Conclusions: Overall, the results showed that AC to be superior to PG in treatment of patients with breast cancer, being less costly and more effective.

• 디지털융복합연구
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• 제11권4호
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• pp.229-234
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• 2013

본 연구의 목적은 감성조명용 조명기기의 조도 및 색온도 표현능력을 극대화할 수 있는 최적의 광원조합을 효율적으로 제어할 수 있는 제어장치를 개발하는데 있다. 실내조명으로 사용할 수 있는 다양한 색온도에 대하여 사람이 편안함을 느끼는 조도영역을 찾아내고 이를 조합함으로서 감성조명을 실현할 수 있다. 이를 위하여 감성조명용 조명기기는 2000K와 8000K의 서로 다른 색온도를 가지는 형광램프로 구성하였으며 각각의 형광램프의 수량을 변화시키며 조명기기의 조도 및 색온도 표현능력을 광학 시뮬레이션을 통하여 평가하였다. 사용자가 원하는 조명환경을 휴식, 대화, 모임, 손님접대, 예술 등의 5가지로 구분하여 적외선 리모콘으로 수신단에 전송하면 수신단에서 PC0~PC4 병렬포트를 통해서 사용자가 선택한 모드에 맞는 DC전압을 출력한다. DC전압이 EEFL 인버터에 입력되고 입력된 DC전압 레벨에 따라 EEFL의 dimming 값이 변하면서 사용자가 원하는 조명환경(조도 및 색온도)를 만들고 인체감지센서를 사용하여 사람이 없을 경우에는 EEFL을 자동으로 꺼지도록 함으로써 소비전력을 절약할 수 있도록 개발하였다.

• Journal of Preventive Medicine and Public Health
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• 제7권2호
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• pp.377-381
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• 1974

Determination of lead in urine is important in industrial hygiene and toxicology. Dithizone method has been principally used for the determination of lead in urine, which gives accurate results in skilful hands but is usually complex and time-consuming. Atomic absorption spectrophotometry is a new simple method and several procedures have been described. However, the influences of pH and the presence of chelating agents during treatment of lead poisoning are not clear. The purpose of this study was to find out the effect of pH and chelating agents on the determination of lead using Shimadzu atomic absorption/flame spectrophotometer, model AA-610. The results obtained were as follows: 1. The atomic absorption spectrophotometry(AAS) could be applied without prior acid digestion to specimens in the absence of chelating agents. The absorbance at $2,170\;{\AA}$, though more sensitive, was more noisy electronically. Therefore, we selected the wavelength of $2,833\;{\AA}$ plus scale expansion. 2. The optimal pH was in the range from 2 to 3. 3. The sensitivity was $0.075{\mu}g/ml/%$ and detection limit was about $0.2{\mu}g/ml$. 4. In the presence of EDTA, lead could not be completely determined without prior acid digestion. 5. On specimens from patients receiving penicillamine therapy, a comparison was made between the values obtained with dithizone method and AAS method with prior acid digestion. The results of comparison showed a very good agreement.

• Journal of Forest and Environmental Science
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• 제34권4호
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• pp.338-351
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• 2018

This study was conducted in a long-term experimental forest in the central hardwoods region of southwestern Michigan to retrospectively examine the role of past forest management practices and climate on red oak (Quercus rubra L.) productivity. Initially, in 1971, plots within the experimental forest were treated separately with a clearcut and shelterwood regeneration harvest in an attempt to increase red oak regeneration. From 1987-1989, a new study was initiated within a portion of the clearcut and shelterwood plots to evaluate the effectiveness of additional oak crop tree release using mechanical and chemical applications. Cumulative diameter and mortality rates of 719 red oaks were monitored across the four silvicultural treatments: Clearcut-A (clearcut without additional release treatment), Clearcut-B (clearcut with additional release treatment), Shelterwood-A (shelterwood without additional release), and Shelterwood-B (shelterwood with additional release) plus an untreated control. Increment cores were obtained from red oak trees and neighboring competitor species. Tree-ring analyses (dendrochronology) were applied to examine the effect of these silvicultural treatments and climatic factors (temperature and precipitation) on red oak productivity. The results indicated that crop tree release following a clearcut or shelterwood harvest reduced mortality rates and thus increased survival of red oak. Red oak in control plots or plots only receiving the initial regeneration harvesting treatment and no additional competition release were negatively affected by climatic stress, which included summer moisture stress. In contrast, red oak in plots that received the competition release treatment from shade tolerant tree species not only had higher tree level productivity (i.e., tree basal area) and lower mortality rates, but were also relatively more resilient to climatic stress by showing limited or no associations between climate and growth.

• 한국물환경학회지
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• 제22권6호
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• pp.1068-1074
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• 2006

For receiving water quality protection a control systems of urban drainage for CSOs reduction is needed. Examples in combined sewer systems include downstream storage facilities that detain runoff during periods of high flow and allow the detained water to be conveyed by an interceptor sewer to a centralized treatment plant during periods of low flow. The design of such facilities as storm-water detention storage is highly dependant on the temporal variability of storage capacity available as well as the infiltration capacity of soil and recovery of depression storage. For the continuous long-term analysis of urban drainage system this study used analytical probabilistic model based on derived probability distribution theory. As an alternative to the modeling of urban drainage system for planning or screening level analysis of runoff control alternatives, this model has evolved that offers much ease and flexibility in terms of computation while considering long-term meteorology. This study presented rainfall and runoff characteristics of the subject area using analytical probabilistic model. Runoff characteristics manifested the unique characteristics of the subject area with the infiltration capacity of soil and recovery of depression storage and was examined appropriately by sensitivity analysis. This study presented the average annual CSOs, number of CSOs and event mean CSOs for the decision of storage volume.

• Asian Pacific Journal of Cancer Prevention
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• 제14권8호
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• pp.4847-4851
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• 2013

Objectives: To evaluate accuracy of FDG-PET CT in prediction of persistent disease in head and neck cancer cases and to determine prognostic value of metabolic tumor response. Materials and Methods: Between 2009 and 2011, 46 patients with squamous cell carcinoma of head and neck receiving PET-CT were treated with definitive radiotherapy, with or without chemotherapy. There were 29 nasopharyngeal, 11 hypopharyngeal, 3 oropharyngeal and 3 laryngeal cancer patients, with a median age of 50.5 years (range 16-84), 32 males and 14 females. All patients were evaluated with PET-CT median 3-5 months (2.4-9.4) after completion of radiotherapy. Results: After a median 20 months of follow up, complete metabolic response was observed in 63% of patients. Suspicious residual uptake was present in 10.9% and residual metabolic uptake in 26.0% of patients. The overall sensitivity, specificity, positive predictive value and negative predictive value of FDG-PET-CT for detection of residual disease was 91% and 81%, 64% and 96% respectively. Two year LRC was 95% in complete responders while it was 34% in non-complete responders. Conclusions: FDG PET CT is a valuable tool for assessment of treatment response, especially in patients at high risk of local recurrence, and also as an indicator of prognosis. Definitely more precise criteria are required for assessment of response, there being no clear cut uptake value indicating residual disease. Futhermore, repair processes of normal tissue may consume glucose which appear as increased uptake in control FDG PET CT.