• Title/Summary/Keyword: Real time imaging

검색결과 537건 처리시간 0.032초

Multimodal Imaging of Sarcopenia using Optical Coherence Tomography and Ultrasound in Rat Model

  • Jeon, Byeong Hwan;Chae, Yu-Gyeong;Hwang, Sang Seok;Kim, Dong Kyu;Oak, Chulho;Park, Eun-Kee;Ahn, Yeh-Chan
    • Journal of the Optical Society of Korea
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    • 제18권1호
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    • pp.55-59
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    • 2014
  • Sarcopenia, or reduced muscle mass and volume, is due to various factors such as senile change, neuronal degeneration, drug, malignancy, and sepsis. Sarcopenia with the aging process has been evidenced by the decline in muscle mass by 0.5 to 1% per year with 3-5% reduction in muscle strength for 10 years between the ages of 40 and 50, and a 1-2% of decline of mass every year in people aged 60-70. Therefore, early diagnosis and understanding the mechanism of sarcopenia are crucial in the prevention of muscle loss. However, it is still difficult to image changes of muscle microstructure due to a lack of techniques. In this study, we developed an animal model using denervated rats to induce a rapid atrophy in the tibialis anterior (TA) and imaged its structural changes using optical coherence tomography (OCT) along with histologic and ultrasound analyses. Ultrasound showed changes of overall muscle size. Histology revealed that the atrophic TA muscle displayed an increased size variability of muscle fiber and inflammatory changes. Three dimensional OCT imaged the changes of perimysial grid and muscle fiber structure in real time without sacrifice. These observed advantages of multimodal imaging using OCT and ultrasound would provide clinical benefits in the diagnosis of sarcopenia.

Preliminary Orbit Determination For A Small Satellite Mission Using GPS Receiver Data

  • Nagarajan, Narayanaswamy;Bavkir, Burhan;John, Ong Chuan Fu
    • 한국항해항만학회:학술대회논문집
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    • 한국항해항만학회 2006년도 International Symposium on GPS/GNSS Vol.1
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    • pp.141-144
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    • 2006
  • The deviations in the injection orbital parameters, resulting from launcher dispersions, need to be estimated and used for autonomous satellite operations. For the proposed small satellite mission of the university there will be two GPS receivers onboard the satellite to provide the instantaneous orbital state to the onboard data handling system. In order to meet the power requirements, the satellite will be sun-tracking whenever there is no imaging operation. For imaging activities, the satellite will be maneuvered to nadir-pointing mode. Due to such different modes of orientation the geometry for the GPS receivers will not be favorable at all times and there will be instances of poor geometry resulting in no output from the GPS receivers. Onboard the satellite, the orbital information should be continuously available for autonomous switching on/off of various subsystems. The paper presents the strategies to make use of small arcs of data from GPS receivers to compute the mean orbital parameters and use the updated orbital parameters to calculate the position and velocity whenever the same is not available from GPS receiver. Thus the navigation message from the GPS receiver, namely the position vector in Earth-Centered-Earth-Fixed (ECEF) frame, is used as measurements. As for estimation, two techniques - (1) batch least squares method, and (2) Kalman Filter method are used for orbit estimation (in real time). The performance of the onboard orbit estimation has been assessed based on hardware based multi-channel GPS Signal simulator. The results indicate good converge even with short arcs of data as the GPS navigation data are generally very accurate and the data rate is also fast (typically 1Hz).

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스마트폰과 임베디드 촬영 모듈을 활용한 구강 환자 관리 시스템 구현 (Implementation of oral patient management system using smartphone and embedded imaging module)

  • 이현섭;윤주상;김진덕
    • 한국정보통신학회논문지
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    • 제22권4호
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    • pp.581-586
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    • 2018
  • 중증 질환 환자의 대부분은 치료 적기를 놓쳐 병을 키우게 된 경우가 많다. 높은 자각 증상이 나타나거나 강력한 통증이 없는 경우 병원 방문을 심각하게 고려하지 않는다. 치은염의 경우 잇몸에서 출혈을 일으키며 치아 붕괴를 일으키는 질환이지만 초기의 증상이 경미하다. 이 시점에서의 병원 치료는 매우 높은 효과를 가진다. 그러나 치료시기를 놓칠 경우 잇몸과 구강의 건강에 심각한 문제를 일으켜 음식을 섭취 할 수없는 상황까지 병증이 진행된다. 본 논문에서는 환자의 치주 이미지를 스마트 폰으로 촬영하여 실시간으로 치의료 기관에 구축된 환자 관리 시스템으로 정보를 전송한다. 전송된 정보를 담당 의사가 판단하며 이에 대한 치료 적기 정보를 환자에게 제공한다.

The Effect Analysis of Compression Method on KOMPSAT Image Chain

  • Yong, Sang-Soon;Ra, Sung-Woong
    • 대한원격탐사학회지
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    • 제23권5호
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    • pp.431-437
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    • 2007
  • Multi-Spectral Camera(MSC) on the KOMPSAT-2 satellite was developed and launched as a main payload to provide 1m of GSD(Ground Sampling Distance) for one(1) channel panchromatic imaging and 4m of GSD for four(4) channel multi-spectral imaging at 685km altitude covering l5km of swath width. Since the compression on MSC image chain was required to overcome the mismatch between input data rate and output date rate JPEG-like method was selected and analyzed to check the influence on the performance. In normal operation the MSC data is being acquired and transmitted with lossy compression ratio to cover whole image channel and full swath width in real-time. In the other hand the MSC performance have carefully been handled to avoid or minimize any degradation so that it was analyzed and restored in KGS(KOMPSAT Ground Station) during LEOP(Launch and Early Operation Phase). While KOMPSAT-2 had been developed, new compression method based upon wavelet for space application was introduced and available for next satellite. The study on improvement of image chain including new compression method is asked for next KOMPSAT which requires better GSD and larger swath width In this paper, satellite image chain which consists of on-board image chain and on-ground image chain including general MSC description is briefly described. The performance influences on the image chain between two on-board compression methods which are or will be used for KOMPSAT are analyzed. The differences on performance between two methods are compared and the better solution for the performance improvement of image chain on KOMPSAT is suggested.

Gadobutrol-dendrimer effects on metastatic and apoptotic gene expression

  • Kebriaezadeh, Abbas;Ashrafi, Sepehr;Rasouli, Rahimeh;Ebrahimi, Seyed Esmaeil Sadat;Hamedani, Morteza Pirali;Assadi, Artin;Saffari, Mostafa;Ardestani, Mehdi Shafiee
    • Advances in nano research
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    • 제4권2호
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    • pp.145-156
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    • 2016
  • Dendrimers are one of the most appropriate nanocaries for imaging moieties in imaging applications.The purpose of this study was the evalution of cytotoxicity and inducing apoptosis of dendrimers. This study was conducted in order to investigate the metastasis suppression effect of dendrimer in human breast MCF-7 cell line and finding the nanoparticle protein corona in biological enviromental. Dendrimer cytotoxicity effect was assessed by MTT assay. The mRNA experession level of KAI1 as a metastasis suppressor gene, Bax as Pro- apoptotic gene, Bcl-2 as an anti-apoptotic gene and GAPDH as a housekepping gene were determined by real-time PCR assays.concentration-dependent nanoparticle cytotoxicity effect was proofed at range of 1-2 mg/mL in 24 hours, significant upregulation of mRNA expression of Bax, was observed whereas expression of anti-apoptotic Bcl-2 was down-regulated, also expression of metastasis suppressor gene KAI1 was up-regulated. So far a few studies confirmed apoptosis enhancement effect of dendrimers in MCF-7 cell line via bax/bcl-2 pathways. dendrimer nanoparticles was able to act as metastase inhibitor via upregulation of KAI1 gene.

요통 환자와 정상인에 적용한 골반저근 수축과 복부 드로우-인이 외측 복부 근육 수축 두께에 미치는 영향 (The Influence of an Abdominal Draw-In Maneuver and Pelvic Floor Muscle Contraction on Lateral Abdominal Muscle Contraction Thickness in Subject with and without Low Back Pain)

  • 윤혜진;김지선;양진모;기경일
    • PNF and Movement
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    • 제13권1호
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    • pp.25-30
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    • 2015
  • Purpose: The aim of this study was to examine the effects of abdominal muscle contraction thickness using real-time ultrasound imaging while applying an abdominal draw-in maneuver (ADIM) and pelvic floor muscle contraction (PFC) to low back pain patients and healthy subjects. Methods: The subjects were 21 young adults; a group of 10 low back pain patients and a control group of 11 healthy subjects. Measurements were made with the subjects on a pillow in a supine position, with the knee joints flexed at 60 degrees. While the two groups conducted ADIM and PFC, their transverse abdominal muscle (TrA), internal abdominal oblique muscle (IO), and external abdominal oblique muscle (EO) thicknesses were measured using an ultrasound imaging system. Result: The TrA muscle contraction thickness ratio during PFC and ADIM was significantly lower in the low back pain group than in the healthy group (p<0.05). The EO muscle contraction thickness ratio during ADIM was also significantly lower in the low back pain group than in the healthy group. The healthy group's muscle contraction thickness ratio was significantly lower during PFC than during ADIM in the TrA, IO, and EO (p<0.05). The low back pain group's muscle contraction thickness ratio was lower during PFC than during ADIM in the TrA, IO, and EO, but the difference was not statistically significant. Conclusion: The results of this study indicate that oral direction during ADIM induced an appropriate contraction of the TrA. Therefore, the procedure reported here may be applied during rehabilitation for appropriate contraction of the TrA.

Bridge Inspection and condition assessment using Unmanned Aerial Vehicles (UAVs): Major challenges and solutions from a practical perspective

  • Jung, Hyung-Jo;Lee, Jin-Hwan;Yoon, Sungsik;Kim, In-Ho
    • Smart Structures and Systems
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    • 제24권5호
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    • pp.669-681
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    • 2019
  • Bridge collapses may deliver a huge impact on our society in a very negative way. Out of many reasons why bridges collapse, poor maintenance is becoming a main contributing factor to many recent collapses. Furthermore, the aging of bridges is able to make the situation much worse. In order to prevent this unwanted event, it is indispensable to conduct continuous bridge monitoring and timely maintenance. Visual inspection is the most widely used method, but it is heavily dependent on the experience of the inspectors. It is also time-consuming, labor-intensive, costly, disruptive, and even unsafe for the inspectors. In order to address its limitations, in recent years increasing interests have been paid to the use of unmanned aerial vehicles (UAVs), which is expected to make the inspection process safer, faster and more cost-effective. In addition, it can cover the area where it is too hard to reach by inspectors. However, this strategy is still in a primitive stage because there are many things to be addressed for real implementation. In this paper, a typical procedure of bridge inspection using UAVs consisting of three phases (i.e., pre-inspection, inspection, and post-inspection phases) and the detailed tasks by phase are described. Also, three major challenges, which are related to a UAV's flight, image data acquisition, and damage identification, respectively, are identified from a practical perspective (e.g., localization of a UAV under the bridge, high-quality image capture, etc.) and their possible solutions are discussed by examining recently developed or currently developing techniques such as the graph-based localization algorithm, and the image quality assessment and enhancement strategy. In particular, deep learning based algorithms such as R-CNN and Mask R-CNN for classifying, localizing and quantifying several damage types (e.g., cracks, corrosion, spalling, efflorescence, etc.) in an automatic manner are discussed. This strategy is based on a huge amount of image data obtained from unmanned inspection equipment consisting of the UAV and imaging devices (vision and IR cameras).

드론을 활용한 교면포장 품질관리 방안에 관한 연구 (A Study on the Quality Control Plan for Bridge Pavement using drones)

  • 송미화;길흥배
    • 한국융합학회논문지
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    • 제13권5호
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    • pp.1-8
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    • 2022
  • 국내에서는 4차 산업혁명의 핵심기술인 드론 등을 이용하여 사회기반시설(SOC)를 디지털화하는 한국판뉴딜 정책을 추진 중에 있고, 국외에서도 열화상카메라 등 융복합센서를 드론에 탑재하여 다양한 산업 분야에서 활용하는 사례가 증가하고 있다. 본 연구에서는 고속도로 교면포장 공사에서 포장 품질을 개선하기 위하여 드론에 열화상 카메라를 탑재하여 포장 작업 구간에 대한 온도 측정 및 검증을 수행하였다. 기존의 방식인 레이저 온도계를 활용한다면 포장 온도를 부분적으로만 측정이 가능하지만, 제안된 방식을 활용하면 포장 작업 구간 전체에 대한 실시간 온도 모니터링 뿐 아니라 온도 분포 확인을 통한 균일성 검증이 가능한 것을 확인하였다. 제안된 방식을 현장에 적용한다면 도로 개방 시기(포장 표면온도≦40℃)에 대한 오판의 가능성을 낮춰줌에 따라 고속도로 포장 품질관리 제고 및 신속한 교통 개방 시기 결정이 가능할 것으로 기대된다.

HWAW 기법의 비수평 출상구조지반 적용에 대한 고찰 (A Study on Application of HWAW Method to the Non-horizontally Layered Soil Structure)

  • 방은석;박헌준;박형춘;김동수
    • 한국지반공학회논문집
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    • 제25권4호
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    • pp.5-17
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    • 2009
  • HWAW 기법은 시간-주파수 해석을 통해 신호/잡음비가 최대가 되는 부분을 이용하여 실험 분산곡선을 획득하고 full wavefield를 고려하는 정모델링 기법을 통해 역산을 수행한다. 따라서 다른 표면파 기법에 비해 짧은 측선 설정이 가능하며 2차원 전단파 속도 분포를 도출하기에 유리하다. 수평층 가정이 성립되지 않는 지반에서의 HWAW 기법 적용성을 평가하기 위해서 수치해석 검증 연구를 수행하였다. HWAW 기법을 통해 각 거 리별로 획득한 실험 분산곡선들은 전반적으로 full wavefield를 고려한 이론 분산곡선과 유사한 형태를 보이는 것을 확인할 수 있었다. 경사면 반사파에 의한 분산곡선의 왜곡현상은 적절한 감지기 간격 조절을 통해 줄여줄 수 있음을 확인할 수 있었다. 도출된 실험 분산곡선은 가진 원으로부터 감지기까지의 영역보다는 감지기 사이 영역에 주되게 영향을 받는 것으로 나타났다. 이로써 HWAW 기법으로 합리적인 전단파 속도 분포의 도출이 가능한 것으로 판단되었으며 고찰한 결과를 바탕으로 실제 현장에서 지반 영상화를 시도하였다.

양식넙치 멜라닌 농축 호르몬의 특성 (Characterization of Melanin-concentrating Hormone from Olive Flounder (Paralichthys olivaceus))

  • 정인영;전정민;송영환
    • 생명과학회지
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    • 제28권3호
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    • pp.284-292
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    • 2018
  • 멜라닌 농축 호르몬(melanin-concentrating hormone, MCH)은 17개의 아미노산으로 구성된 환형의 시상하부 펩티드로 색소 침착의 조절인자로서 연어에서 처음 분리되었다. 포유동물의 MCH는 19개의 아미노산으로 구성되어 있으며 섭식 및 에너지 항상성을 조절하는데 관여한다. 본 연구에서는 양식넙치의 다양한 조직에서 MCH 유전자의 발현 분포, 멜라닌 함유 세포의 집적, 포유동물 MCH 수용체와 양식넙치 MCH의 상호작용을 조사하였다. Real-time qPCR을 이용하여 뇌, 정소, 난소에서 MCH 유전자의 발현이 나타나는 것을 확인하였고, 수정 후 발달 단계에서도 MCH 유전자의 발현을 확인할 수 있었다. 합성된 연어 sMCH, 포유류 hMCH, 양식넙치 fMCH, dN-fMCH, dC-fMCH를 양식 넙치의 표피에 처리했을 때 다양한 농도에 따라 멜라닌 함유 세포의 집적이 다양하게 나타났다. 연어 sMCH, 포유류 hMCH에 비해 양식넙치 fMCH의 멜라닌 함유세포의 집적도가 36~99.85%로 비역가를 나타났으나 양식넙치 dN-fMCH, dC-fMCH를 처리한 경우 양식넙치 fMCH에 비해 높은 농도에서 집적이 나타나고 짧은 시간에 분산되었다. 또한, 인간 MCH 수용체와 쥐 MCH 수용체가 발현된 포유동물의 세포주에 양식넙치 fMCH를 처리하여 각 수용체와 결합하는 것을 확인하였다. 이러한 결과는 어류에서 발현되는 MCH가 포유동물의 MCH와 유사한 구조를 가지고 있어 MCH 수용체에 대한 새로운 리간드로서 제공될 수 있으며, 향후 어류의 MCH 수용체에 확대 적용할 수 있을 것이다.