• Journal of Distribution Science
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• v.12 no.2
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• pp.17-25
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• 2014

Purpose - This study used empirical methods to investigate the consciousness structure of vendors in the S marketing area, which is a commercial revitalization district in the country, and examined its effect on their business activities. Based on the results derived through the performance of an actual proof analysis, this study aims to facilitate the promotion of changes in the consciousness structures of traditional market vendors, with a view to allowing them to adapt to the current economic realities in the country. Further, this study aims to provide suggestions that would improve the efficiency of the commercial revitalization program of the government. Research design, data, and methodology - This study examined all the stores in the S marketing area using a questionnaire survey conducted over three weeks beginning on July 4, 2012, and involved the performance of a data analysis on 1,859 samples. The questionnaire consisted of two parts. The first part addressed the market revitalization and the second part addressed the store management strategies. Questionnaire responses were calibrated based on a Likert scale. Statistical analysis was conducted using PASW version 18.0. Results - The results of the analysis of the consciousness structure of merchants in the S marketing area have led to the discovery that they have a medium level of satisfaction with market revitalization. There was a difference in the perceptions of the concept of store management between merchants and customers. Merchants have poor strategies for store management, which do not go much beyond an imitation of the practices of large domestic discount stores. Conclusions - The appearance of big discount stores and the accompanying changes in people's consumption patterns have led to a decline in local market areas. The government has sought new ways to secure autogenic power for local markets. To create regional economies, the government enacted a revised "Law for creating traditional markets and shopping streets" in 2010 and introduced a commercial district revitalization program. This program, which originally supported only the S marketing area, has subsequently expanded into neighboring shopping districts so that the whole of the regional market can be revitalized. However, since the revitalization of the traditional market and the government support required for it were mostly limited to facilities, the result has not proved to be effective. Although there are several reasons why the government investment was characterized by poor efficiency, traditional market vendors' consciousness structure, which did not adapt well to the vagaries of time and its consequent changes, was a major cause. Only when vendors have a true merchant spirit can they have a real service focus that will enable them to clearly understand the distribution organization. This will have the effect of bring about complete customer satisfaction and will ensure the survival and development of traditional markets.

• Journal of Korean Society for Atmospheric Environment
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• v.34 no.5
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• pp.727-734
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• 2018

In this study, real-time absorption coefficients of carbonaceous species in $PM_{2.5}$ was observed using a dual-spot 7-wavelength Aethalometer between November 1, 2016 and December 31, 2017 at an urban site of Gwangju. In addition, 24-hr integrated $PM_{2.5}$ samples were simultaneously collected at the same site and analyzed for organic carbon and elemental carbon (OC and EC) using the thermal-optical transmittance protocol. A main objective of this study was to estimate mass absorption cross section (MAC) values of black carbon (BC) particles at the study site using the linear regression between aethalometer-based absorption coefficient and filter-based EC concentration. BC particles observed at 880 nm is mainly emitted from combustion of fossil fuels, and their concentration is typically reported as equivalent BC concentration (eBC). eBC concentration calculated using MAC value of $7.77m^2/g$ at wavelength of 880 nm, which was proposed by a manufacturer, ranged from 0.3 to $7.4{\mu}g/m^3$ with an average value of $1.9{\pm}1.2{\mu}g/m^3$, accounting for 7.3% (1.5~20.9%) of $PM_{2.5}$. The relationship between aerosol absorption coefficients at 880 nm and EC concentrations provided BC MAC value of $15.2m^2/g$, ranging from 11.4 to $16.2m^2/g$. The eBC concentrations calculated using the estimated MAC of $15.2m^2/g$ were significantly lower than those reported originally from aethalometer, and ranged from 0.2 to $3.8{\mu}g/m^3$, with an average of $1.0{\pm}0.6{\mu}g/m^3$, accounting for 3.7% of $PM_{2.5}$ (0.8~10.7%). Result from this study suggests that if the MAC value recommended by the manufacturer is applied to calculate the equivalent BC concentration and radiative forcing due to BC absorption, they would result in significant errors, implying investigation of an unique MAC value of BC particles at a study site.

• Resources Recycling
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• v.27 no.1
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• pp.31-37
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• 2018

To enhance the recycling rate of used metal resources, it is strongly desired to develop a metal sorting system that can automatically identify metal type from mixed metal scraps and sort them separately. Laser-induced breakdown spectroscopy(LIBS) is a technique that enables real time classification of different metals based on multi-elemental and in-air analysis. In this work, we report the results of LIBS elemental analysis of field scrap samples acquired from a recycling company. By applying multivariate analysis, it was found that the LIBS signals of five different metals could be perfectly classified if surface contamination was removed. The classification accuracy degraded for LIBS signals including contaminant emission, which however could be overcome by performing the multivariate analysis using properly selected emission lines of higher correlation only. The significant improvement in classification accuracy and process speed by the selection of proper emission lines demonstrated the feasibility of LIBS technique as an industrial tool for metal scrap sorting.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.10
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• pp.4281-4287
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• 2014

Background: Methylation of tumor suppressor genes has been investigated in all kinds of cancer. Tumor specific epigenetic alterations can be used as a molecular markers of malignancy, which can lead to better diagnosis, prognosis and therapy. Therefore, the aim of this study was to evaluate the association between gene hypermethylation and expression of fragile histidine triad (FHIT), glutathione S-transferase P1 (GSTP1) and p16 genes and various clinicopathologic characteristics in primary non-small cell lung carcinomas (NSCLC). Materials and Methods: The study included 28 primary non-small cell lung carcinomas, where an additional 28 tissue samples taken from apparently normal safety margin surrounding the tumors served as controls. Methylation-specific polymerase chain reaction (MSP) was performed to analyze the methylation status of FHIT, GSTP1 and p16 while their mRNA expression levels were measured using a real-time PCR assay with SYBR Green I. Results: The methylation frequencies of the genes tested in NSCLC specimens were 53.6% for FHIT, 25% for GSTP1, and 0% for p16, and the risk of FHIT hypermethylation increased among patients with NSCLC by 2.88, while the risk of GSTP1 hypermethylation increased by 2.33. Hypermethylation of FHIT gene showed a highly significant correlation with pathologic stage (p<0.01) and a significant correlation with smoking habit and FHIT mRNA expression level (p<0.05). In contrast, no correlation was observed between the methylation of GSTP1 or p16 and smoking habit or any other parameter investigated (p>0.05). Conclusions: Results of the present study suggest that methylation of FHIT is a useful biomarker of biologically aggressive disease in patients with NSCLC. FHIT methylation may play a role in lung cancer later metastatic stages while GSTP1 methylation may rather play a role in the early pathogenesis.

• Journal of the Korean Society of Food Science and Nutrition
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• v.45 no.1
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• pp.27-34
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• 2016

Garlic has drawn attention as a food material for its anti-oxidative and anti-inflammatory properties as well as for prevention and treatment of cancer. In order to increase efficiency, various aging methods for garlic have been attempted. In particular, thermally processed garlic is known to have higher biological activities due to its various chemical changes during heat treatment. Therefore, in this study, we investigated the anti-oxidative effects of garlic extracts aged at low temperature ($60{\sim}70^{\circ}C$). In the results, 2,2-diphenyl-1-picrylhydrazyl and 2,2-azino-bis (3-ethylbenzo-thiazoline-6-sulfonate) radical scavenging activities and ferric reducing ability of low temperature-aged garlic (LTAG) were similar to those of raw garlic. LTAG also showed decreased lipopolysaccharide (LPS)-induced production of reactive oxygen species, although there were not significant differences among samples. In addition, xanthine oxidase activity was inhibited by LTAG; the 15 days and $60^{\circ}C$ extract showed outstanding inhibition compared with the others. To understand the molecular mechanisms behind the anti-oxidative activity of LTAG, we performed quantitative real-time PCR analysis. The 30 days and $70^{\circ}C$ extract upregulated mRNA expression of antioxidant enzymes such as Cu/Zn-superoxide dismutase (SOD), Mn-SOD, glutathione peroxidase, and catalase in LPS-stimulated RAW 264.7 cells. This result indicates that LTAG can be a functional food as a nature antioxidant and antioxidant substance.

• Journal of the Korean earth science society
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• v.26 no.1
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• pp.41-57
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• 2005

The purpose of the study is to develop a educational data in order for students to perform geologic field survey effectively by themselves. A area around the Duta Mountain is selected. which is located at the southeastern part of Eumsung sedimentary basin because various rock types and geologic structures are well shown in this area and also it is convenient to reach there. Thirteen stops for observation are chosen m a route f3r exercising field geologic investigation. Data for field research are given and described in detail from each stop for observation. To do this, students make their own route map using general or digital geographic map and aerial photo is added to know relationship between large-scale structure and different rock types regionally. Moreover, it is designed to minimize conflict factors that may be experienced from the real field survey by showing outcrop photographs and polarizing photomicrographs of rut samples related to each stop and geologic structures. The attitude of students is investigated with the data of field geologic survey for students of an Earth Science class in the College of Education in Chungbuk National University. The results indicate that the educational data for geologic field survey brought positive changes that greatly help students perform field survey in definitive side, especially formation of absolute concepts on earth science.

• The Korean Society of Law and Medicine
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• v.10 no.2
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• pp.455-492
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• 2009

(Background) Recent biotechnological breakthroughs are shedding new lights on various ethical and legal issues about human biological material. Since Rudolph Virchow, a German pathologist, had founded the medical discipline of cellular pathology, issues centering around human biological materials began to draw attention. The issues involving human biological materials were revisited with more attention along with series concerns when the human genome map was finally completed. Recently, with researches on human genes and bioengineering reaping enormous commercial values in the form of material patent, such changes require a society to reassess the present and future status of human tissue within the legal system. This in turn gave rise to a heated debate over how to protect the rights of material donors: property rule vs. no property rule. (Debate and Cases) Property rule recognizes the donors' property rights on human biological materials. Thus, donors can claim real action if there were any bleach of informed consent or a donation contract. Donors can also claim damages to the responsible party when there is an infringement of property rights. Some even uphold the concept of material patents overtaking. From the viewpoint of no property rule, human biological materials are objects separated from donors. Thus, a recipient or a third party will be held liable if there were any infringement of donor's human rights. Human biological materials should not be commercially traded and a patent based on a human biological materials research does not belong to the donor of the tissues used during the course of research. In the US, two courts, Moore v. Regents of the University of California, and Greenberg v. Miami Children's Hospital Research Institute, Inc., have already decided that research participants retain no ownership of the biological specimens they contribute to medical research. Significantly, both Moore and Greenberg cases found that the researcher had parted with all ownership rights in the tissue samples when they donated them to the institutions, even though there was no provision in the informed consent forms stating either that the participants donated their tissue or waived their rights to ownership of the tissue. These rulings were led to huge controversy over property rights on human tissues. This research supports no property rule on the ground that it can protect the human dignity and prevent humans from objectification and commercialization. Human biological materials are already parted from human bodies and should be treated differently from the engineering and researches of those materials. Donors do not retain any ownership. (Suggestions) No property rule requires a legal breakthrough in the US in terms of donors' rights protection due to the absence of punitive damages provisions. The Donor rights issue on human biological material can be addressed through prospective legislation or tax policies, price control over patent products, and wider coverage of medical insurance. (Conclusions) Amid growing awareness over commercial values of human biological materials, no property rule should be adopted in order to protect human dignity but not without revamping legal provisions. The donors' rights issue in material patents requires prospective legislation based on current uncertainties. Also should be sought are solutions in the social context and all these discussions should be based on sound medical ethics of both medical staffs and researchers.

• Parasites, Hosts and Diseases
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• v.54 no.4
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• pp.519-525
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• 2016

To investigate the potential role of transforming growth factor (TGF)-${\beta}1$ in liver fibrosis during Echinococcus granulosus infection, 96 BALB/c mice were randomly divided into 2 groups, experimental group infected by intraperitoneal injection with a metacestode suspension and control group given sterile physiological saline. The liver and blood samples were collected at days 2, 8, 30, 90, 180, and 270 post infection (PI), and the expression of TGF-${\beta}1$ mRNA and protein was determined by real-time quantitative RT-PCR and ELISA, respectively. We also evaluated the pathological changes in the liver during the infection using hematoxylin and eosin (H-E) and Masson staining of the liver sections. Pathological analysis of H-E stained infected liver sections revealed liver cell edema, bile duct proliferation, and structural damages of the liver as evidenced by not clearly visible lobular architecture of the infected liver, degeneration of liver cell vacuoles, and infiltration of lymphocytes at late stages of infection. The liver tissue sections from control mice remained normal. Masson staining showed worsening of liver fibrosis at the end stages of the infection. The levels of TGF-${\beta}1$ did not show significant changes at the early stages of infection, but there were significant increases in the levels of TGF-${\beta}1$ at the middle and late stages of infection (P<0.05). RT-PCR results showed that, when compared with the control group, TGF-${\beta}1$ mRNA was low and comparable with that in control mice at the early stages of infection, and that it was significantly increased at day 30 PI and remained at high levels until day 270 PI (P<0.05). The results of this study suggested that increased expression of TGF-${\beta}1$ during E. granulosus infection may play a significant role in liver fibrosis associated with E. granulosus infection.

• The Journal of Society for e-Business Studies
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• v.14 no.4
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• pp.229-253
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• 2009

The effect of knowledge sharing and its importance have been reported in the information systems literature. However, little has been learned about the impact of knowledgeexchange web sites. This study explores relationships between individual characteristics such as personal innovativeness in the domain of information technology (PIIT), computer selfefficacy (CSE), and computer anxiety (CA), user involvement (UI), and knowledge sharing in a knowledge.exchange website. In order to examine our research model, we adopted a survey research design based on the Structural Equation Modeling method. By analyzing 241 samples collected, we conclude that UI and CA are valuable to discuss in terms of their theoretical and practical implications. This study not only extends the research on personal innovativeness and knowledge sharing, but also suggests a need for focused research efforts to investigate real practices on knowledge sharing. This study initiates this kind of efforts to make a relevant tie between design of knowledge sharing applications and the success case in the commercial field to encourage users to share their knowledge.

• School Mathematics
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• v.12 no.3
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• pp.273-299
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• 2010

The purpose of the study is designing and implementing 'Sampling Distributions Simulation' to help students to understand concepts of sampling distributions. This computer simulation is developed to help students understand sampling distributions more easily. 'Sampling Distributions Simulation' consists of 4 sessions. 'The first session - Confidence level and confidence intervals - includes checking if the intended confidence level is actually achieved by the real relative frequency for the obtained sample confidence intervals containing population mean. This will give the students clearer idea about confidence level and confidence intervals in addition to the role of sampling distribution of the sample means among those. 'The second session - Sampling Distributions - helps understand sampling distribution of the sample means, through the simulation method to make comparison between the histogram of sampling distributions and that of the population. The third session - The Central Limit Theorem - includes calculating the means of the samples taken from a population which follows a uniform distribution or follows a Bernoulli distribution and then making the histograms of those means. This will provides comprehension of the central limit theorem, which mentions about the sampling distribution of the sample means when the sample size is very large. The forth session - the normal approximation to the binomial distribution - helps understand the normal approximation to the binomial distribution as an alternative version of central limit theorem. With the practical usage of the shareware 'Sampling Distributions Simulation', we expect students to have a new vision on the sampling distribution and to get more emphasis on it. With the sound understandings on the sampling distributions, more accurate and profound statistical inferences are expected. And the role of the sampling distribution in the inferences should be more deeply appreciated.