• IMMUNE NETWORK
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• 제11권4호
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• pp.203-209
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• 2011

Background: T cell immunoglobulin mucin containing molecule (TIM)-3 is expressed in differentiated Th1 cells and is involved in the suppression of the cytokine production by these cells. However, the regulation of the expression of other T cell genes by TIM-3 is unclear. Herein, we attempted to identify differentially expressed genes in cells abundantly expressing TIM-3 compared to cells with low expression of TIM-3. Methods: TIM-3 overexpressing cell clones were established by transfection of Jurkat T cells with TIM-3 expression vector. For screening of differentially expressed genes, gene fishing technology based on reverse transcription-polymerase chain reaction (RT-PCR) using an annealing control primer system was used. The selected candidate genes were validated by semi quantitative and real-time RT-PCR. Results: The transcription of TIMP-1, IFITM1, PAR3 and CCL1 was different between TIM-3 overexpressing cells and control cells. However, only CCL1 transcription was significantly different in cells transiently transfected with TIM3 expression vector compared with control cells. CCL1 transcription was increased in primary human $CD4^+$ T cells abundantly expressing TIM-3 but not in cells with low expression of TIM-3. Conclusion: CCL1 was identified as a differentially transcribed gene in TIM-3-expressing $CD4^+$ T cells.

• IMMUNE NETWORK
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• 제12권5호
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• pp.207-212
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• 2012

T cell immunoglobulin mucin domain (TIM)-3 is an immunomodulatory molecule and upregulated in T cells by several cytokines. TIM-3 also influences mast cell function but its transcriptional regulation in mast cells has not been clarified. Therefore, we examined the transcript level and the promoter activity of TIM-3 in mast cells. The TIM-3 transcript level was assessed by real-time RT-PCR and promoter activity by luciferase reporter assay. TIM-3 mRNA levels were increased in HMC-1, a human mast cell line by TGF-${\beta}1$ stimulation but not by stimulation with interferon (IFN)-${\alpha}$, IFN-${\lambda}$, TNF-${\alpha}$, or IL-10. TIM-3 promoter -349~+144 bp region relative to the transcription start site was crucial for the basal and TGF-${\beta}1$-induced TIM-3 promoter activities in HMC-1 cells. TIM-3 promoter activity was increased by over-expression of Smad2 and Smad4, downstream molecules of TGF-${\beta}1$ signaling. Our results localize TIM-3 promoter activity to the region spanning -349 to ＋144 bp in resting and TGF-${\beta}1$ stimulated mast cells.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제12권6호
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• pp.2922-2945
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• 2018

Achieving efficient authentication is a crucial issue for stream data commonly seen in content delivery, peer-to-peer, and multicast/broadcast networks. Stream authentication mechanisms need to be operated efficiently at both sender-side and receiver-side at the same time because of the properties of stream data such as real-time and delay-sensitivity. Until now, many stream authentication mechanisms have been proposed, but they are not efficient enough to be used in stream applications where the efficiency for sender and receiver sides are required simultaneously since most of them could achieve one of either sender-side and receiver-side efficiency. In this paper, we propose an efficient stream authentication mechanism, so called TIM, by integrating Trapdoor Hash Function and Merkle Hash Tree. Our construction can support efficient streaming data processing at both sender-side and receiver-side at the same time differently from previously proposed other schemes. Through theoretical and experimental analysis, we show that TIM can provide enhanced performance at both sender and receiver sides compared with existing mechanisms. Furthermore, TIM provides an important feature for streaming authentication, the resilience against transmission loss, since each data block can be verified with authentication information contained in itself.

• 대한음성학회지:말소리
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• 제51호
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• pp.85-98
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• 2004

It is almost impossible to generate the sound field effect in real time with the time-domain linear convolution because of its large multiplication operation requirement. To solve this, three methods are introduced to reduce the number of multiplication operations in this paper. Firstly, the time-domain linear convolution is replaced with the frequency-domain circular convolution. In other words, the linear convolution result can be derived from that of the circular convolution. This technique reduces the number of multiplication operations remarkably, Secondly, a subframe concept is introduced, i.e., one original frame is divided into several subframes. Then the FFT is executed for each subframe and, as a result, the number of multiplication operations can be reduced. Finally, the QFT is used in stead of the FFT. By combining all the above three methods into our final the SFE generation algorithm, the number of computations are reduced sufficiently and the real-time SFE generation becomes possible with a general PC.

• 한국융합학회논문지
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• 제3권1호
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• pp.1-5
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• 2012

본 논문에서는 안드로이드 기반의 스마트 단말기를 이용하여 실시간 영상전송시스템을 구현하였다. 스마트 단말기에 내장된 카메라를 통해 획득한 영상 이미지를 프레임 단위로 서버를 통해 원격지의 안드로이드 단말로 전송하도록 하였으며, 실제 3G 이동통신망을 통해 전송한 결과 초당 16프레임까지의 영상을 끊김 없이 전송함을 확인하였다. 이를 활용할 경우 별도의 고가 카메라를 구비하지 않고도 스마트 단말기의 내장 카메라만으로 실시간 방송이나 영상 채팅 등에 적용할 수 있을 것으로 기대한다.

• 한국위성정보통신학회논문지
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• 제10권4호
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• pp.83-86
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• 2015

본 논문에서는 수처리 시설용 광대역 통합망 연계 실시간 계측관리 시스템 UI 개발을 제안한다. 수처리시설용 광대역 통합망을 통해 서버로 수신된 센서 및 영상 데이터를 Web과 연동하기 위한 프로그램을 개발하며, 이와 별도로 독립적으로 운영이 가능한 UI를 개발한다. 전송된 센서 및 영상데이터를 원격 모니터링 하기 위한 웹 서버를 구축하며 센서 데이터, 영상 데이터를 Web기반의 UI를 통해 감시 및 제어가 가능하도록 개발하였다. 제안하는 수처리 시설용 광대역 통합망 연계형 실시간 계측관리 시스템을 통하여 센서를 통한 측정시간, 농도, 수심 계면 등의 현재 상태를 파악할 수 있으며 영상 모니터링을 통하여 실시간으로 수처리 시설의 정상적인 동작여부와 보안 및 화재 등의 인명피해 여부를 확인 할 수 있다. 뿐만 아니라 실시간 계측 관리 시스템을 실시간으로 모니터링 할 수 있는 UI 개발로 인해 실시간으로 정보를 한눈에 볼 수 있다.

• 제어로봇시스템학회논문지
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• 제11권11호
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• pp.913-919
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• 2005

An advanced method of Relaxed Static Stability (RSS) is utilized for improving the aerodynamic performance of modem version supersonic jet fighter aircraft. The flight control system utilizes RSS criteria in both longitudinal and lateral-directional axes to achieve performance enhancements and improve stability. Standard CLDA (Control Law Design and Analysis) process is provided that reduce the development period of the flight control system. In addition, if this process is employed in developing flight control laws, it reduces the trial and error development and verification of control laws. This paper details the design process of developing a flight control law for the RSS aircraft, utilizing military specifications, linear and nonlinea, analysis using XMATH and ATLAS(Aircraft, Tim Linear and Simulation), handling quality tests using the HQS (Handling Quality Simulator), and real flight test results to verify aircraft dynamic flight responses.

• Communications for Statistical Applications and Methods
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• 제25권4호
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• pp.431-442
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• 2018

This paper highlights the computational explosion issues in the autoregressive moving average approach of frequency estimation of sinusoidal data with a large sample size. A new algorithm is proposed to circumvent the computational explosion difficulty in the conditional least-square estimation method. Notice that sinusoidal pattern can be generated by a non-invertible non-stationary autoregressive moving average (ARMA) model. The computational explosion is shown to be closely related to the non-invertibility of the equivalent ARMA model. Simulation studies illustrate the computational explosion phenomenon and show that the proposed algorithm can efficiently overcome computational explosion difficulty. Real data example of sunspot number is provided to illustrate the application of the proposed algorithm to the time series data exhibiting sinusoidal pattern.

• ETRI Journal
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• 제38권5호
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• pp.911-921
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• 2016

This paper presents the description, practical implementation, and stability analysis of a recently proposed, energy-efficient, medium access control protocol for wireless sensor networks, ALOHA-Q, which employs a reinforcement-learning framework as an intelligent transmission strategy. The channel performance is evaluated through a simulation and experiments conducted using a real-world test-bed. The stability of the system against possible changes in the environment and changing channel conditions is studied with a discussion on the resilience level of the system. A Markov model is derived to represent the system behavior and estimate the time in which the system loses its operation. A novel scheme is also proposed to protect the lifetime of the system when the environment and channel conditions do not sufficiently maintain the system operation.

• 한국인터넷방송통신학회논문지
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• 제10권1호
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• pp.91-96
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• 2010

동심원 모자이크는 공통의 공간적인 기준을 사용하여 비디오 분할의 프레임들을 정렬시키거나 합쳐서 형성된다. 과거의 3차원 웨이브렛 변환 코딩의 연구와 비교하여 유연한 부분적 부호화와 비트 스트림의 임의 검색을 가능하게 하여주는 중요한 구성을 고려하여 압축된 동심 모자이크의 just-in-tim(JIT) 표현 알고리즘을 제안하였다. 이 동심 모자이크의 JIT 표현이 실시간 표현을 수행하기 위해서는 많은 계산량이 요구된다. 압축된 형태로 데이터가 유지되어 특정 장면을 표현하기 위해 사용되는 내용만이 복호 되어야 한다. 그래서 제안된 알고리즘은 웨이브렛을 리프팅 계산식의 구조를 사용하여 동심 모자이크의 실시간 표현을 가능하게 해준다.