• Title/Summary/Keyword: Read Rate

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A Comparative Analysis of the Illumina Truseq Synthetic Long-read Haplotyping Sequencing Platform versus the 10X Genomics Chromium Genome Sequencing Platform for Haplotype Phasing and the Identification of Single-nucleotide variants (SNVs) in Hanwoo (Korean Native Cattle) (일루미나에서 제작된 TSLRH (Truseq Synthetic Long-Read Haplotyping)와 10X Genomics에서 제작된 The Chromium Genome 시퀀싱 플랫폼을 이용하여 생산된 한우(한국 재래 소)의 반수체형 페이징 및 단일염기서열변이 비교 분석)

  • Park, Woncheoul;Srikanth, Krishnamoorthy;Park, Jong-Eun;Shin, Donghyun;Ko, Haesu;Lim, Dajeong;Cho, In-Cheol
    • Journal of Life Science
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    • v.29 no.1
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    • pp.1-8
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    • 2019
  • In Hanwoo cattle (Korean native cattle), there is a scarcity of comparative analysis papers using highdepth sequencing and haplotype phasing, particularly a comparative analysis of the Truseq Synthetic Long-Read Haplotyping sequencing platform serviced by Illumina (TSLRH) versus the Chromium Genome Sequencing platform serviced by 10X Genomics (10XG). DNA was extracted from the sperm of a Hanwoo breeding bull (ID: TN1505D2184/27214) provided by Hanwoo research canter and used for the generation of sequence data from both the sequencing platforms. We then identified SNVs using an appropriate analysis pipeline tailored for each platform. The TSLRH and 10XG platforms generated a total of 355,208,304 and 1,632,772,004 reads, respectively, corresponding to a Q30 (%) of 89.04% and 88.60%, respectively, of which 351,992,768(99.09%) and 1,526,641,824(93.50%) were successfully mapped. For the TSLRH and 10XG platforms, the mean depth of the sequencing was 13.04X and 74.3X, the longest phase block was 1,982,706 bp and 1,480,081 bp, the N50 phase block was 57,637 bp and 114,394 bp, the total number of SNVs identified was 4,534,989 and 8,496,813, and the total phased rate was 72.29% and 87.67%, respectively. Moreover, for each chromosome, we identified unique and common SNVs using both sequencing platforms. The number of SNVs was directly proportional to the length of the chromosome. Based on our results, we recommend the use of the 10XG platform for haplotype phasing and SNV identification, as it generated a longer N50 phase block, in addition to a higher mean depth, total number of reads, total number of SNVs, and phase rate, than the TSLRH platform.

A Read-In Integrated Circuit for IR Scene Projectors Adopting a Sub-Frame Control Technique for Minimizing the Temperature Loss (온도 손실의 최소화를 위해 Sub-Frame 제어 기법을 적용한 적외선 영상 투사기용 신호입력회로)

  • Shin, Uisub;Cho, Min Ji;Kang, Woo Jin;Jo, Young Min;Lee, Hee Chul
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.8
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    • pp.113-118
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    • 2016
  • In this paper, a read-in integrated circuit (RIIC) for IR scene projectors (IRSPs) adopting a sub-frame control technique is proposed, which minimizes the reduction of the apparent temperature of the IR images projected from IRSPs operating at a frame rate of 30 Hz. The proposed sub-frame control technique significantly reduces the amount of scene data loss on capacitors, which is caused by leakage currents flowing through MOSFET switches during holding periods, by dividing a unit frame into 8 sub-frames and refreshing the same scene data for each sub-frame. A current-drive RIIC was designed for the higher apparent temperature of IR radiated from the emitter, and it receives the scene data as a form of analog voltages from an external DAC. A prototype chip with a $64{\times}32$ RIIC array was fabricated using Magnachip/SKhynix $0.35{\mu}m$ 2-poly 4-metal CMOS process, and the measured maximum output data current is $230.3{\mu}A$. This amount of current ensures the projection of IR images whose maximum apparent temperature is $366.2^{\circ}C$ in the mid-wavelength IR (MWIR) when applied to a prototype emitter having a resistance of $15k{\Omega}$.

Block Replacement Scheme based on Reuse Interval for Hybrid SSD System (Hybrid SSD 시스템을 위한 재사용 간격 기반 블록 교체 기법)

  • Yoo, Sanghyun;Kim, Kyung Tae;Youn, Hee Yong
    • Journal of Internet Computing and Services
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    • v.16 no.5
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    • pp.19-27
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    • 2015
  • Due to the advantages of fast read/write operation and low power consumption, SSD(Solid State Drive) is now widely adopted as storage device of smart phone, laptop computer, server, etc. However, the shortcomings of SSD such as limited number of write operations and asymmetric read/write operation lead to the problem of shortened life span of SSD. Therefore, the block replacement policy of SSD used as cache for HDD is very important. The existing solutions for improving the lifespan of SSD including the LARC scheme typically employ the LRU algorithm to manage the SSD blocks, which may increase the miss rate in SSD due to the replacement of frequently used block instead of rarely used block. In this paper we propose a novel block replacement scheme which considers the block reuse interval to effectively handle various data read/write patterns. The proposed scheme replaces the block in SSD based on the recency decided by reuse interval and age along with hit ratio. Computer simulation using workload trace files reveals that the proposed scheme consistently improves the performance and lifespan of SSD by increasing the hit ratio and decreasing the number of write operations compared to the existing schemes including LARC.

Epigraph Reading by Photographic Reading Techniques - Focused on Pyeongwangtapbi Monument of Seonggak Daesa - (사진 탁본 기법을 이용한 금석문 판독 - 무위사 선각대사편광탑비를 중심으로 -)

  • Jang, Seon Phil;Hahn, Sang June
    • Korean Journal of Heritage: History & Science
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    • v.44 no.2
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    • pp.58-75
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    • 2011
  • This study aimed to demonstrate that photographic reading can be used to decipher epigraphs more effectively and accurately than conventional rubbing of epigraphy. When using the rubbing technique, the reading rate varies for the each epigraph depending on the time, person, and rubbing method. Thus, we compared the results of conventional rubbing to photographic reading focusing on unread and misread letters. According to the results, some letters were different from those in the reference books, and some letters that could have been readable via photographic reading were misread or read as different letters. In its undamaged state, the Pyeongwangtapbi Monument of Seonggak Daesa is supposed to contain a total of 2,049 letters, and 1,763 of them have been deciphered. This study corrected a total of 308 letters that had not been deciphered or deciphered inconsistently in existing literatures. However, it should be noted that the epigraphs of the Pyeongwangtapbi Monument of Seonggak Daesa read using the rubbing technique were made at least 30-100 years ago, and the photographic reading was performed in 2010. Thus, the overall condition is not perfectly identical. If we read and compare in the same condition, we may obtain even more reliable results. Therefore, based on this study of photographic reading, further studies regarding the correction of the contents of epigraphy should be performed.

Variations of Air Temperature, Relative Humidity and Pressure in a Low Pressure Chamber for Plant Growth (식물생장용 저압챔버 내의 기온, 상대습도 및 압력의 변화)

  • Park, Jong-Hyun;Kim, Yong-Hyeon
    • Journal of Bio-Environment Control
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    • v.18 no.3
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    • pp.200-207
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    • 2009
  • This study was conducted to analyze the variations of air temperature, relative humidity and pressure in a low pressure chamber for plant growth. The low pressure chamber was composed of an acrylic cylinder, a stainless plate, a mass flow controller, an elastomer pressure controller, a read-out-box, a vacuum pump, and sensors of air temperature, relative humidity, and pressure. The pressure leakage in the low pressure chamber was greatly affected by the material and connection method of tubes. The leakage rate in the low pressure chamber with the welding of the stainless tubes and a plate decreased by $0.21kPa{\cdot}h^{-1}$, whereas the leakage in the low pressure chamber with teflon tube and rubber O-ring was given by $1.03kPa{\cdot}h^{-1}$. Pressure in the low pressure chamber was sensitively fluctuated by the air temperature inside the chamber. An elastomer pressure controller was installed to keep the pressure in the low pressure chamber at a setting value. However, inside relative humidity at dark period increased to saturation level.. Two levels (25 and 50kPa) of pressure and two levels (500 and 1,000sccm) of mass flow rate were provided to investigate the effect of low pressure and mass flow rate on relative humidity inside the chamber. It was concluded that low setting value of pressure and high mass flow rate of mixed gas were the effective methods to control the pressure and to suppress the excessive rise of relative humidity inside the chamber.

A Study on the Technology Measuring Partial Discharge for Long Term Aging Experiments of Insulation Materials (장시간 절연체 열화실험을 위한 부분방전측정기술 연구)

  • Seon, Jong-Ho;Kim, Gwang-Hwa;Park, Jeong-Hu;Jo, Jeong-Su
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.49 no.12
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    • pp.665-672
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    • 2000
  • This paper described the measurement technology to analyze the partial discharge characteristics for long term aging of insulations. This system was consisted of high voltage generation and measurement part, PD detection part, digital conversion and signal processing part. We used the VXI system for digital conversion and signal processing part. In the digital conversion part, we studied the error of partial discharge magnitude and memory capacity for reading digital signal with the sampling rate. In the signal processing part, we showed the program algorithm to count pulses and read peak values of partial discharge. The allowable minimum sampling rate of digizer was decided to 250kS/s through analyzing test. We confirmed that this system was very useful in the study of $\phi-q-n$ characteristics of long term PD experiments with specimens being consisted of internal void defects and CIGRE II electrodes.

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Satellite Link Simulator Development in 100 MHz Bandwidth to Simulate Satellite Communication Environment in the Geostationary Orbit (정지궤도 위성통신 환경모의를 위한 100 MHz 대역폭의 위성링크 시뮬레이터 개발)

  • Lee, Sung-Jae;Kim, Yong-Sun;Han, Tae-Kyun
    • Journal of the Korea Institute of Military Science and Technology
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    • v.14 no.5
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    • pp.842-849
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    • 2011
  • The transponder simulator designed to simulate the transponder of military satellite communication systems in the geostationary orbit is required to have time delay function, because of 250 ms delay time, when a radio wave transmits the distance of 36,000 km in free space. But, it is very difficult to develop 250 ms time delay device in the transponder simulator of 100 MHz bandwidth, due to unstable operation of FPGA, loss of memory data for the high speed rate signal processing. Up to date, bandwidth of the time delay device is limited to 45 MHz bandwidth. To solve this problem, we propose the new time delay techniques up to 100 MHz bandwidth without data loss. Proposed techniques are the low speed down scaling and high speed up scaling methods to read and write the external memory, and the matrix structure design of FPGA memory to treat data as high speed rate. We developed the satellite link simulator in 100 MHz bandwidth using the proposed new time delay techniques, implemented to the transponder simulator and verified the function of 265 ms time delay device in 100 MHz bandwidth.

Determination of Optimal Combination of Optical Filter for Recognizing Financial Account Using Statistical Analysis (통계적 분석에 의한 금융통장 인식용 광학필터 최적 조합 선정에 관한 연구)

  • Yu, Hyeung Keun;Lee, Kang Won
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.27 no.5
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    • pp.328-341
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    • 2014
  • The object of this paper is to develop optimal optical filter, which can be used to identify the financial account and read the information. The five factors which affect the performance of the optical filter are identified as optical glass type, existence of Fe, Photo pic coating type, and coating form. In this study we seek to determine the optimal combination for the best design of the optical filter. For each combination, the performances of optical filter are investigated using the proper experimental equipments and methods. White-state voltage, black-state voltage, and black-state error rate are used for the performance measures. Through the statistical analysis of the performance data collected, we have determined the optimal design of the optical filter.

Numerical Analysis of Heat Transfer in Packed Bed of $Ca(OH)_2/CaO$ for Chemical Heat Pump ($Ca(OH)_2/CaO$계 화학 열펌프에 있어서 고체 반응층의 전열해석)

  • Kim, Jong-Shik
    • Solar Energy
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    • v.17 no.1
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    • pp.67-77
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    • 1997
  • To develop chemical heat pump of higher energy density and efficiency heat-release characteristics accompanied by exothermic hydration reaction in packed bed, $Ca(OH)_2/CaO$ reactor, are examined in a lab-scale unit. We have studied the enhancement effect of inserted fins in cylindical packed bed reactor. The results obtained by numerical analysis about profiles of temperature, completion time of reaction and exothermic heat amount released from the reactor read the insertion of fins in reactor can reduce the reaction completion time by half and the rate of thermochemical reaction depends on the temperature and concentration, and it is also governed by the boundary conditions and the rate of heat transfer in the particle packed bed.

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ERRATUM: 'LONG-TERM X-RAY VARIABILITIES OF SEYFERT GALAXY MCG-2-58-22: GRADUAL DECREAES AND FLARES' (JKAS, 35, 1, [2002])

  • CHOI CHUL-SUNG;DOTANI TADAYASU;CHANG HEON- YOUNG;YI INSU
    • Journal of The Korean Astronomical Society
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    • v.36 no.2
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    • pp.73-73
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    • 2003
  • Proof correction to the equation in the third paragraph of the DISCUSSION AND CONCLUSION has not been carried faithfully to the published version of the paper. The corrected equation should read ${\approx}10^{-3}\;M_8^4/^3(N_{\ast}/10^6\;pc^{-3})({\sigma}/300 km\;s^{-l})^{-l}(r/r_t)\;yr^{-1}$, where Ms is the mass of the SMBH in units of $10^8\;M_{\bigodot}$, $\sigma$ is the virial velocity of the stars, $r_t$ is the tidal radius of the SMBH. This estimates the frequency that a star would pass within a sphere with the radius r from the SMBH, rather than the frequency of the tidal disruption event. Therefore, it increases with the mass of the SMBH. However, the loss cone effect should also be taken into account, which reduces the actual event rate. Here, we adopted a factor of one hundred to consider the deficiency from the isotrophic rate. The authors sincerely regret this error.