• Title/Summary/Keyword: Rates of application

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Application of Human Papillomavirus in Screening for Cervical Cancer and Precancerous Lesions

  • Wang, Jin-Liang;Yang, Yi-Zhuo;Dong, Wei-Wei;Sun, Jing;Tao, Hai-Tao;Li, Rui-Xin;Hu, Yi
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.5
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    • pp.2979-2982
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    • 2013
  • Cervical cancer is a commonly-encountered malignant tumor in women. Cervical screening is particularly important due to early symptoms being deficient in specificity. The main purpose of the study is to assess the application value of cervical thinprep cytologic test (TCT) and human papillomavirus (HPV) detection in screening for cervical cancer and precancerous lesions. In the study, cervical TCT and HPV detection were simultaneously performed on 12,500 patients selected in a gynecological clinic. Three hundred patients with positive results demonstrated by cervical TCT and/or HPV detection underwent cervical tissue biopsy under colposcopy, and pathological results were considered as the gold standard. The results revealed that 200 out of 12,500 patients were abnormal by TCT, in which 30 cases pertained to equivocal atypical squamous cells (ASCUS), 80 cases to low squamous intraepithelial lesion (LSIL), 70 cases to high squamous intraepithelial lesion (HSIL) and 20 cases to squamous cell carcinoma (SCC). With increasing pathological grade of cervical biopsy, however, TCT positive rates did not rise. Two hundred and eighty out of 12,500 patients were detected as positive for HPV infection, in which 50 cases were chronic cervicitis and squamous metaplasia, 70 cases cervical intraepithelial neoplasia (CIN) I, 60 cases CIN II, 70 cases CIN III and 30 cases invasive cervical carcinoma. Two hundred and thirty patients with high-risk HPV infection were detected. With increase in pathological grade, the positive rate of high-risk HPV also rose. The detection rates of HPV detection to CIN III and invasive cervical carcinoma as well as the total detection rate of lesions were significantly higher than that of TCT. Hence, HPV detection is a better method for screening of cervical cancer at present.

Influence of pre-planting application of dolomite at various rates in coir-dust containing root media on the growth of red-leaf lettuce

  • Kim, Chang Hyeon;Choi, Jong Myung
    • Korean Journal of Agricultural Science
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    • v.43 no.2
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    • pp.176-185
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    • 2016
  • This research was conducted to evaluate various levels of dolomitic lime incorporated as pre-planting fertilizers on the growth of red-leaf lettuce. To achieve this, three root media were formulated by mixing coir dust with expanded rice hull (CD+ERH, 8:2, v/v), carbonized rice hull (CD+CRH, 6:4, v/v), and ground pine bark (CD+GRPB, 6:4, v/v). During formulation, equal amounts of essential nutrients, except dolomitic lime, were incorporated into all root media and the levels of dolomitic lime were varied from 0 to $7.5g\;L^{-1}$ at 1.5 g increments. Seedlings of red-leaf lettuces at the 3rd leaf stage were transplanted into each medium treatment. Crop growths were measured 5 weeks after transplant and soil solutions were collected every week and analyzed for pH, EC, and nutrient concentrations. The treatments showing the heaviest fresh and dry weights in CD+ERH, CD+CRH, and CD+GRPB were 4.5 g, 4.5 g, and $7.5g\;L^{-1}$ of dolomite, respectively. The pHs of three root media yielding the highest crop growths were in the ranges of 6.4 to 7.1. These ECs in CD+CRH medium were around $1.0dS\;m^{-1}$ higher than those of CD+ERH and CD+GRPB when application rates of dolomitic lime were equal. $K^+$ concentrations were higher than $Ca^{+2}$ and $Mg^{+2}$ concentrations until week 2 in three root media. But $Ca^{+2}$ and $Mg^{+2}$ concentrations were higher than $K^+$ concentrations after week 3 in all root media. The concentrations of $PO_4{^{-3}}$ in all root media got abruptly lower until week 2. These results indicate that appropriate levels of dolomitic lime, as pre-planting nutrient charge fertilizers in CD+ERH and CD+GRPB media, are 4.5 and $7.5g\;L^{-1}$, respectively.

Two Stage Deep Learning Based Stacked Ensemble Model for Web Application Security

  • Sevri, Mehmet;Karacan, Hacer
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.16 no.2
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    • pp.632-657
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    • 2022
  • Detecting web attacks is a major challenge, and it is observed that the use of simple models leads to low sensitivity or high false positive problems. In this study, we aim to develop a robust two-stage deep learning based stacked ensemble web application firewall. Normal and abnormal classification is carried out in the first stage of the proposed WAF model. The classification process of the types of abnormal traffics is postponed to the second stage and carried out using an integrated stacked ensemble model. By this way, clients' requests can be served without time delay, and attack types can be detected with high sensitivity. In addition to the high accuracy of the proposed model, by using the statistical similarity and diversity analyses in the study, high generalization for the ensemble model is achieved. Within the study, a comprehensive, up-to-date, and robust multi-class web anomaly dataset named GAZI-HTTP is created in accordance with the real-world situations. The performance of the proposed WAF model is compared to state-of-the-art deep learning models and previous studies using the benchmark dataset. The proposed two-stage model achieved multi-class detection rates of 97.43% and 94.77% for GAZI-HTTP and ECML-PKDD, respectively.

APPLICATION AND EVALUATION OF THE GLEAMS MODEL TO A CATTLE GRAZING PASTURE FIELD IN NORTH ALABAMA

  • Kang, M. S.;P. prem, P.-Prem;Yoo, K. H.;Im, Sang-Jun
    • Water Engineering Research
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    • v.5 no.2
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    • pp.55-68
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    • 2004
  • The GLEAMS (Groundwater Loading Effects of Agricultural Management System, version 3.0) water quality model was used to predict hydrology and water quality and to evaluate the effects of soil types from a cattle-grazed pasture field of Bermuda-Rye grass rotation with poultry litter application as a fertilizer in North Alabama. The model was applied and evaluated by using four years (1999-2002) of field-measured data to compare the simulated results for the 2.71- ha Summerford watershed. $R^2$ values between observed and simulated runoff, sediment yields, TN, and TP were 0.91, 0.86, 0.95, and 0.69, respectively. EI (Efficiency Index) of these parameters were 0.86, 0.67, 0.70, and 0.48, respectively. The statistical parameters indicated that GLEAMS provided a reasonable estimation of the runoff, sediment yield, and nutrient losses at the studied watershed. The soil infiltration rates were compared with the rainfall events. Only high intensity rainfall events generated runoff from the watershed. The measured and predicted infiltration rates were higher during dry soil conditions than wet soil conditions. The ratio of runoff to precipitation was ranging from 2.2% to 8.8% with average of 4.3%. This shows that the project site had high infiltration and evapotranspiration which generated the low runoff. The ratio of runoff to precipitation according to soil types by the GLEAMS model appeared that Sa (Sequatchie fine sandy loam) soil type was higher and Wc (Waynesboro fine sandy loam, severely eroded rolling phase) soil type relatively lower than the weighted average of the soil types in the watershed. The model under-predicted runoff, sediment yields, TN, and TP in Wb (Waynesboro fine sandy loam, eroded undulating phase) and Wc soil types. General tendency of the predicted data was similar for all soil types. The model predicted the highest runoff in Sa soil type by 105% of the weighted average and the lowest runoff in Wc soil type by 87% of the weighted average

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The Effect of Auricular Reflexology Therapy in Musculoskeletal Disease (근골격계(筋骨格系) 질환(疾患)에 있어서 이혈요법(耳穴療法)의 효과(效果))

  • Yeo, Yeongman;Chong, Myongsoo
    • Journal of Korean Medical Ki-Gong Academy
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    • v.11 no.1
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    • pp.221-235
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    • 2009
  • This study is made for the survey of the effectiveness of the auricular reflexology, now accepted as a part of alternative medicine, applied to the patients of musculoskeltal disease patients, and data about its cognition and the success rate of the therapy. 106 patient was employed in this study who works in various part in a company in Jun-ju in Junrabukdo. From them, data such as, musculoskeletal symptoms by questionnaire examination, and data from ear inspections and interviews were collected and used for the basal data. Auricular reflexology therapies were applied to them at the areas that reflect the musculoskeletal system, for five times, each time with intervals of three or four days. The data about the effectiveness were collected by questionnaire examination, including descriptive answers. The results are as follows; cognition to the auricular reflexology was 62.3%, and acceptance rate of this method was 81.1%. From this results, I think that this therapy can be easily acceptable. The success rates of this therapy were 32.1% after 1 time application, and 84.9% after 5 times applications. This result shows that auricular reflexology therapy has therapeutic effect in musculoskeletal diseases, and the success rates increase according to the application times. Between sex, its success rate were 80% in male patients, and 88.5% in female patients, so this therapy is rather more effective in female patients. According to the body weight, the success rate were 85.8% in normal weight patients, and 71.5% in over- weight patients, so this therapy is more effective in normal weight patients. Comparisons according to other factors, such as age, marriage state etc. shows no definite differences. Conclusively, I think that auricular reflex therapy is easy and useful preventative and treatment method in our usual life. With more investigation, we can apply this method to other musculoskeletal diseases and to the diseases of other systems in the body, I hope so.

Clinical Differences and Outcomes of Continuous Renal Replacement Therapy between Critically Ill Neonates and Children (신생아와 소아의 지속적 신대체요법(CRRT) 적용 특성 및 결과)

  • Choi, Aeng Ja;Choi, Su Jung;Choi, Hee Jung;You, Mi Young
    • Journal of Korean Critical Care Nursing
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    • v.9 no.1
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    • pp.40-50
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    • 2016
  • Purpose: Continuous renal replacement therapy (CRRT) has become the preferred dialysis method to support critically ill children and neonates with acute kidney injury. Using CRRT on neonates has increased, but reports about experience are limited. The aim of this study is to describe the clinical application, outcomes, and complications of CRRT in children and neonates. Methods: A retrospective review was performed in 135 children and 36 neonates who underwent CRRT at a tertiary hospital from 2008 to 2015. Results: At the initiation of CRRT, the median age of children was 72 months and the corrected age of neonates was 37.1 weeks. Median body weight of neonates was 3.2 kg. In neonates, initial degree of fluid overload [FO%], blood flow rate [BFR] and ultrafiltration rate [UFR] rate during CRRT were higher than in children. Median real time of CRRT was 90.5 and 53.5 hours in children and neonates, respectively. Downtime of CRRT was 0.7 and 1.3 hours/day. Median mortality rates (44.4% vs.47.2%) and complication rates were similar between the groups. Conclusion: CRRT can be used for a wide range of critically ill children and neonates. Different application methods of CRRT can contribute to increased survival of neonates.

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No frequency change of prehospital treatments by emergency medical services providers for traumatic cardiac arrest patients before and after the COVID-19 pandemic in Korea: an observational study

  • Ju Heon Lee;Hyung Il Kim
    • Journal of Trauma and Injury
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    • v.36 no.3
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    • pp.172-179
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    • 2023
  • Purpose: Out-of-hospital traumatic cardiac arrest (TCA) often has a poor prognosis despite rescue efforts. Although the incidence and mortality of out-of-hospital cardiac arrest have increased, bystander cardiopulmonary resuscitation (CPR) has decreased in some countries during the COVID-19 pandemic. In the prehospital setting, immediate treatment of cardiac arrest is required without knowing the patient's COVID-19 status. Because COVID-19 is usually transmitted through the respiratory tract, airway management can put medical personnel at risk for infection. This study explored whether on-scene treatments involving CPR for TCA patients changed during the COVID-19 pandemic in Korea. Methods: This retrospective study used data from emergency medical services (EMS) run sheets in Gangwon Province from January 2019 to December 2021. Patients whose initial problem was cardiac arrest and who received CPR were included. Data in 2019 were classified as pre-COVID-19 and all subsequent data (from 2020 and 2021) as post-COVID-19. Age, sex, possible cause of cardiac arrest, and treatments including airway maneuvers, oropharyngeal airway (OPA) or i-gel insertion, endotracheal intubation (ETI), bag-valve mask (BVM) ventilation, intravenous (IV) line establishment, neck collar application, and wound dressing with hemostasis were investigated. Results: During the study period, 2,007 patients received CPR, of whom 596 patients had TCA and 367 had disease-origin cardiac arrest (DCA). Among the patients with TCA, 192 (32.2%) were pre-COVID-19 and 404 (67.8%) were post-COVID-19. In the TCA group, prehospital treatments did not decrease. The average frequencies were 59.7% for airway maneuvers, 47.5% for OPA, 57.4% for BVM, and 51.3% for neck collar application. The rates of ETI, i-gel insertion, and IV-line establishment increased. The treatment rate for TCA was significantly higher than that for DCA. Conclusions: Prehospital treatments by EMS workers for patients with TCA did not decrease during the COVID-19 pandemic. Instead, the rates of ETI, i-gel insertion, and IV-line establishment increased.

Application of the Load Duration Curve (LDC) to Evaluate the Rate of Achievement of Target Water Quality in the Youngsan · Tamjin River Watersheds (부하지속곡선(LDC)을 이용한 영산강 · 탐진강수계 오염총량관리 목표수질 평가방법 적용 방안)

  • Cheong, Eunjeong;Kim, Hongtae;Kim, Yongseok;Shin, Dongseok
    • Journal of Korean Society on Water Environment
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    • v.32 no.4
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    • pp.349-356
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    • 2016
  • Total Maximum Daily Loads (TMDLs) System has been used to improve water quality in the Youngsan·Tamjin river basin since 2004. The Basic Policy of TMDLs sets up the standard flow based on the average dry condition or mid-range flow during the last 10 years. However, Target Water Quality (TWQ) assessment on TMDLs has been used to evaluate water quality through eight-day intervals over 36 times a year. The results for allocation evaluation and target water quality evaluation were different from each other in the same unit watershed during the first period. In order to improve the evaluation method, researchers applied Load Duration Curve (LDC) to evaluate water quality in nine unit watersheds of the Youngsan·Tamjin river basin. The results showed that achievement rates of TWQ assessment with the current method and LDC were 67~100% and 78~100%, respectively. Approximately 11% of the achievement rates with use of LDC were higher than those with use of the current method. In conclusion, it is necessary to review the application of the LDC method in all Four Major River Watersheds.

A Survey for the Recognition and Adoption Rates Concerning the Application of Preceptorship into the Pharmacy Education Settings (프리셉터 제도의 도입과 활용에 관한 인식 및 수용도에 대한 조사연구)

  • Bang, Joon-Seok;Jang, Jung-Joon;Kim, Su-Jin;Sohn, Uy-Dong;Sim, Sang-Soo;Cheong, Ji-Hoon;Choi, Byung-Chul
    • Korean Journal of Clinical Pharmacy
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    • v.18 no.1
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    • pp.50-59
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    • 2008
  • Objective: The aim for this article was to evaluate and to clarify the current opinions of the registered pharmacists concerning their recognition and adoption rates about introducing the preceptorship into the clinical pharmacy internship and clerkship. Methods: A 25-question-questionnaire was developed and pilot tested. For 40 days of survey by both on-line and on site, 90 over 240 (37.5%) registered pharmacists responded and the data were analyzed with comparison to the groups working in community and hospital pharmacies. Results: The overall answers were affirmative and the respondents were very interested in the application of the clinical preceptorship to the pharmacy educational and to their clinical settings. Moreover, the qualification level and the implementation methods were proposed in detail. Conclusion: Although ninety pharmacists showed their views differently, most of the respondents regarded the preceptorship as an adequate training system for the pharmacy students as well as junior pharmacists at the time of initiation of the new 6-year pharmacy education system in Korea.

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efficiency of Mineral Nitrogen Fertilization on Yield and Botanical Composition of Grassland I. Dry matter yield and economical mineral nitrogen of grassland (무기태 질소시비가 초지의 수량과 식생구성에 미치는 영향 I. 초지의 수량과 경제적 무기태 질소시비한계)

  • ;G. Schechtenr
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.10 no.2
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    • pp.102-109
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    • 1990
  • This experiment was carried out to study the effect of pure mineral nitrogen fertilizing on dry matter yield of grassland and the advisable mineral nitrogen amounts in long duration under practical conditions at the "Federal Institute for Agriculture in the Alps" in Austria. The application rates were 0, 30, 60,90 and 120 kg N/ha/cut, the cutting regimes 3-, 4-, 5- and 6-cuts/year. In order to explain the nitrogen-profitability were determined that 1 kg pure mineral nitrogen have to produce 8 - 16 kg DM/kg N in dependence on cutting regimes and requiring of nitrogen efficiencies. The results were as follows: 1. With only PK-fertilizaing average dry matter yields from 4.0 to 7.6 tons per ha and year were obtained. 2. Within all applied cutting regimes 60 kg min. Nlhalgrowth have proved to be the most efficient application rate witn 13 - 24 kg DM/kg N in dependent of cutting regimes. Comapred with only PK-treatment the DM yields increased by 3.9 - 4.7 t/ ha nad year. 3. By the sigmaformed process of Input-Output curve the highest marginal yield (the "most efficient" Ndressing rate) per ha and year was calculated: 152 kg N at 3-cut regimes, 204 kg N at 4-cut regimes, 220 kg N at 5-cut regimes and 240 kg N/ha/year at 6-cut regimes. 4. With required efficiencies of 16 and 12 kg DM/kg N 240 - 300 kg N per ha and year respectively would have to be applied at 3-cut regimes; with required efficiencies of 12 and 10 kg DM/kg N at 4-cut regimes the appropriate figures ranged from 320 to 420 kg N/ha and year, at 5- and 6-cut regimes and efficiencies of 10 and 8 kg DM/kg N results of 360 - 460 kg N and 380 - 500 kg N respectively were obtained. 5. At the relatively dry location Piber the highest dressing rates were needed in order to obtain the efficiencies from 8 to 16 kg DM/kg N, about 30 - 60 kg N/ha/year more than at the relatively moist location Admont.ist location Admont.

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