• Title/Summary/Keyword: Rare and incurable disease

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Domestic Clinical Research Trends of Pharmacopuncture Treatment for Nerve Entrapment Syndroeme: A Scoping Review (포착신경병증의 약침치료에 대한 국내 임상 연구 동향: 주제범위 문헌고찰)

  • Woenhyung Lee;Hyeonjun Woo;Yunhee Han;Seungkwan Choi;Jungho Jo;Byeonghyeon Jeon;Wonbae Ha;Junghan Lee
    • Journal of Korean Medicine Rehabilitation
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    • v.33 no.4
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    • pp.31-44
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    • 2023
  • Objectives The purpose of this study is to check the research trends of pharmacopuncture treatment in nerve entrapment syndrome, identify specific techniques, identify which pharmacopuncture are used, and provide directions for future research. Methods This study was conducted based on the five steps suggested by Arksey and O'Malley. We searched five domestic databases (Research Information Sharing Service, Oriental Medicine Advanced Searching Integrated System, Korean studies Information Service System, Science ON, and KMBASE) and identified studies with key search terms like "nerve entrapment" And "pharmacopuncture" until June 23, 2023. Results Twenty-nine studies were finally selected. among them, 25 papers were non-comparative studies (86.2%). The most common disease was carpal tube syndrome (n=10). All the investigated studies were treated by injecting pharmacopuncture into the pathway of the entraped nerve. The depth of pharmacopuncture injection was mentioned only in 13 studies. As for the pharmacopuncture used, sweet bee venom was 8 studies and bee venom was 6 studies, and about half of the pharmacopuncture manufactured with Bee venom as the main component accounted for. Conclusions This study is a scoping review of the pharmacopuncture treatment for nerve entrapment, which was first conducted in Korea. The treatment is mainly performed on the path way of the entraped nerve. After that, it is necessary to study the standardization of the specific technique method of pharmacopuncture and the uniformity of evaluation criteria.

A Case of Primary Pulmonary Hypertension in Pregnancy Presented as Massive Hemoptysis (임신 중 대량객혈로 발현된 원발성 폐고혈압 1예)

  • Kim, Myung Sook;Kim, Hyoung Doo;Kim, Seok Chan;Kwan, Soon Suk;Kim, Young Kyoon;Kim, Kwan Hyoung;Moon, Hwa Sik;Song, Jeong Sup;Park, Sung Hak
    • Tuberculosis and Respiratory Diseases
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    • v.57 no.1
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    • pp.66-71
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    • 2004
  • Primary pulmonary hypertension (PPH) is a rare, progressive and incurable disease, which is characterized by an increase in the pulmonary artery pressure without a demonstrable cause. The most common presenting symptom is dyspnea on exertion, with other symptoms comprising of chest pain, syncope and hemoptysis. The diagnosis is one of exclusion of any of the known causes of pulmonary hypertension. When associated with pregnancy, the maternal mortality ranges from 30 to 50%. Because pregnancy and labor are very serious problems for patients with PPH, the available evidence suggests that pregnancy when afflicted with PPH should be avoided. In account the case of a 33-year old patient, reporting with massive hemoptysis, and diagnosed with PPH during her twenty seventh week of gestation, is presented. She was treated with conservative management, including oxygen and a vasodilator, and underwent a pregnancy termination. However, due to aggravation of right heart failure, she presented with severe systemic hypotension and hypoxemia, and eventually died. This case is reported, with brief review of the literature.