• Title/Summary/Keyword: Rapid R&D

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Development of Key Performance Index(KPI) for R&D expenditure activities focusing on efficiency of patent (R&D지출의 효율성 측면에서 특허를 이용한 KPI 개발: 특허효율성지표(PEI: Patent Efficiency Index))

  • Lee, Joon-Ho;Ha, Seong-Tae;Bae, Byung-Han;Yu, Si-Mon;Kim, Dae-Sung;Han, Min-Hyun
    • Journal of Technology Innovation
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    • v.20 no.3
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    • pp.29-55
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    • 2012
  • In order to successfully adopt and implement the Balanced Scorecard(BSC), firms need to respond adequately to the rapid changes of today's business environment and consider the growing importance of non financial factors in the business activities such as intangible assets(R&D expenditure, patent, goodwill, etc.). Our primary focus throughout this paper is on developing Key Performance Index(KPI) of BSC for R&D expenditure activities. In this study, we have developed and named PEI(Patent Efficiency Index),which is the KPI for R&D expenditure by focusing on the efficiency of a patent that is the output from the R&D expenditures. Secondarily, we have attempted to address the solution for the current problems of the traditional R&D performance measurement by using our developed PEI and examine the usefulness and effectiveness of the newly developed our PEI. According to the empirical test results, we find that the PEI is positively associated with ROA and Tobin's Q, respectively and show that our developed PEI is more effective and accurate than the traditional R&D performance measurement as a business performance measurement. Furthermore, these findings proves that we can measure and evaluate how efficiently the firms perform the R&D activities and shows that the PEI can be a critical index for evaluating firm's business performance related to the R&D expenditures.

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The Factors on Somatic Embryogenesis of Soybean [Glycine max. (L.) Merrill]

  • Kim, Kyong-Ho;Kim, Hag-Sin;Oh, Young-Jin;Suh, Sug-Kee;Kim, Tae-Soo;Park, Ho-Kee;Park, Moon-Soo;Kim, Seok-Dong;Yeo, Up-Dong
    • Journal of Plant Biotechnology
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    • v.2 no.3
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    • pp.123-128
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    • 2000
  • To enhance in vitro plantlet regeneration efficiency of soybean through embryogenesis, the culture conditions such as material part and size of immature seed, 2,4-D, pH and solidifying agents for somatic embryogenesis were investigated. Somatic embryogenesis was induced from the immature embryo, immature cotyledon and embryonic axis explants of the immature seed on MS medium supplemented with 2.0 mg/L 2,4-D. The highest rate (up to 22.9%) of somatic embryogenesis was obtained from the immature cotyledon, following embryonic axis and the immature embryo. The rate varied with the developmental stages of seed. The maximum rate (25.4%) of embryogenesis was obtained from 3-4 mm length of the seed (after 25 days of flowering). The optimum concentration of 2,4-D for embryogenesis was 10 mg/L. The optimum pH was at 5.8 and solidifying agent for medium was better with 0.4% gelrite than with agar. For rapid multiplication of shoot tips from the germinating somatic embryos, they were cultured on MS medium containing 2 mg/L indole-3-butyyic acid (IBA) and 1 mg/L 6-benzyladenine (BA). After then somatic embryos with one and three cotyledons were transferred to the growth regulator free medium. The medium exhibited the higher rate (ca. 50%) of development than the multiplication medium.

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A Study on R&D Investment Decision Making Model by Using Small-Medium Enterprises Strategic Technology Roadmap (전략기술로드맵 기반의 중소기업 R&D 투자우선순위 결정모형에 관한 연구)

  • Kyung, Jong-soo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.12
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    • pp.786-794
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    • 2018
  • In recent years, in response to rapid technological change, technology planning activities are important for companies to cope with technological competition. However, Small and Medium Enterprises(SMEs) lack the resources and competence to establish their own technology roadmaps. Therefore, government-led roadmaps for SMEs have been proposed to support the R&D direction and R&D capabilities of SMEs. However, SMEs R&D policies are still not well linked with technology roadmaps and R&D programs. In other words, the size of R&D for SMEs is determined according to demand of SMEs regardless of strategic technology roadmap. In this study, we propose a investment prioritization model based on a technology road map to unify R&D investment policy. Using the decision model designed to prioritize strategic technology investments in the SME strategy roadmap, we conduct empirical analysis of strategic technologies in the advanced convergence and green manufacturing. AHP analysis was conducted after questionnaires on the importance of strategic technology and the importance of influential factors to 46 experts such as expert of research institutes and support organizations.

Evaluation of in vitro antibacterial Activity of DWP20373, a Novel Fluoroquinolone (플로오로퀴놀론계 항생제인 DWP20373의 in vitro 항균작용)

  • Kim, Ji-Yeon;Choi, Moon-Jung;Han, Seung-Hee;Kim, Byung-O;Shim, Jeom-Soon;Jung, Yeon-Eui;Lee, Jae-Wok;Yu, Young-Hyo;Park, Myung-Hwan
    • YAKHAK HOEJI
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    • v.40 no.3
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    • pp.357-368
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    • 1996
  • The in vitro antibacterial activity of a novel fluoroquinolone, DWP20373(1-Cyclopropyl-6-fluoro-8-methoxy-7-(2,7-diazabicyclo[3,3,0]oct-4-ene-7-yl)-1,4-dihydro-4 oxoquino line-3carboxylic acid) was compared with those of ciprofloxacin (CPFX), sparfloxacin (SPFX) and ofloxacin (OFLX). DWP20373 was more active than SPFX and OFLX but was less potent than CPFX against gram-negative bacteria. DWP20373 showed an excellent activity against L-MRSA and H-MRSA ($MlC_{90}=0.781{\sim}1.563{\mu}g/ml$).The activity of DWP20373 decreased moderately in the presence of 5mM $Mg^{2+}$. However, pH and serum had no effect on the activity of DWP20373. DWP20373 possessed a rapid bactericidal activity against gram-positive and gram-negative strains.

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Acute Hemodynamic Effects of CJ-10513, an Angiotensin IIReceptor Antahonest, in Dog Treated with High Friquency Ventricular Pacing (안지오텐신 ll 수용체 길항약 CJ-10513이 고민도 심실 pacing 천에서의 혈행동태에 미치는 영향)

  • Kim, Young-Hoon;Jeong, Seong-Mok;Shin, Jae-Kyu;Choi, Jae-Mook;Jeong, Seong-Hak;Bae, Hoon;Lee, Gun-Ho;Kim, Je-Hak;An, Yang-Soo
    • Biomolecules & Therapeutics
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    • v.6 no.2
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    • pp.199-203
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    • 1998
  • Acute hemodynamic effects of CJ-18513, a non-peptide angiotensin IIreceptor antagonist, were examined in mongrel dogs treated with high frequency ventricular pacing for one week. Rapid ventricular pacing reduced mean blood pressure (mBP), Lvdp/dt and cardiac output (CO), and increased the left ventricular end-diastolic pressure (LVEDP) and pulmonary capillary wedge pressure (PCWP). Continuous infusion of CJ-10513 at doses of 10 and 20$\mu$g/kg/min, respectively, for 30 minutes reduced mBP, LVEDP and myocardial oxygen consumption rate (MVO,) and shifted the cardiac function curve (CO-LVEDP ourve) to the left in this dog model. In conclusion, CJ-10513 decreased the preload and afterload and increased the cardiac function in dogs with pacing-induced heart failure.

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Development of Fast Screening Method for Crop Protection Agents in Tobacco by Stir Bar Sorptive Extraction and Thermal Desorption coupled to GC/MS

  • Min, Hye-Jeong;Lee, Jeong-Min;Shin, Han-Jae;Lee, Moon-Yong;Jang, Gi-Chul
    • Journal of the Korean Society of Tobacco Science
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    • v.36 no.1
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    • pp.26-33
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    • 2014
  • Simultaneous determination of crop protection agents(CPAs) in food are done with multi-residue methods, which are composed of sample clean-up, concentration, chromatographic separation and detection. Stir Bar Sorptive Extraction(SBSE) technique is used for sample preparation of various analytes in several fields. The aim of this study was to develop a sensitive and fast method based on SBSE followed by thermal desorption - gas chromatography - mass spectrometry(TD - GC/MS) to determine CPAs in tobacco sample. For the analysis of tobacco sample prior to the SBSE method, solvent extraction or ultrasound-assisted solvent extraction was performed. methanol was used as the extraction solvent. The extract was then diluted with water. Finally, the sample was subjected to SBSE. A method for fast screening of crop protection agents in tobacco using SBSE-TD - GC/MS has been developed. About 17 CPAs including organochlorine, organophosphorous and others were identified and quantified. This method showed good linearity and high sensitivity for most of the target CPAs. The method was applied to the determination of CPAs at ng/mL levels in tobacco sample. This method is simple, rapid and may be applied in detection of other components.

Design and Implementation of 30" Geometry PIG

  • Kim, Dong-Kyu;Cho, Sung-Ho;Park, Seoung-Soo;Yoo, Hui-Ryong;Park, Yong-Woo
    • Journal of Mechanical Science and Technology
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    • v.17 no.5
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    • pp.629-636
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    • 2003
  • This paper introduces the developed geometry PIG (Pipeline Inspection Gauge), one of several ILI (In-Line Inspection) tools, which provide a full picture of the pipeline from only single pass, and has compact size of the electronic device with not only low power consumption but also rapid response of sensors such as calipers, IMU and odometer. This tool is equipped with the several sensor systems. Caliper sensors measure the pipeline internal diameter, ovality and dent size and shape with high accuracy. The IMU (Inertial Measurement Unit) measures the precise trajectory of the PIG during its traverse of the pipeline. The IMU also provide three-dimensional coordination in space from measurement of inertial acceleration and angular rate. Three odometers mounted on the PIG body provide the distance moved along the line and instantaneous velocity during the PIG run. The datum measured by the sensor systems are stored in on-board solid state memory and magnetic tape devices. There is an electromagnetic transmitter at the back end of the tool, the transmitter enables the inspection operators to keep tracking the tool while it travels through the pipeline. An experiment was fulfilled in pull-rig facility and was adopted from Incheon LT (LNG Terminal) to Namdong GS (Governor Station) line, 13 km length.

Evaluation on R&D Progress for Manganese Nodule Development and Its Prospects (심해저 망간단괴 개발사업의 국제기술 동향 분석 및 향후 개발 전망)

  • Park, Se-Hun;Park, Seong-Wook;Kang, Gil-Mo
    • Ocean and Polar Research
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    • v.27 no.4
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    • pp.477-490
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    • 2005
  • The development of manganese nodule mining technology is very important in order to secure a long-term and stable supply of rare strategic metals. In the twenty years following the R&D activities with the international consortia in the 1970s, studies on mining technologies have been carried out by several national projects in Korea. The current metal prices such as copper, nickel, cobalt, and manganese have been drastically changed since 2002. Rapid economic growth of Asian countries, especially China, have induced the situation. And the possibility of copper shortage is looming just around the comer. Because of the imbalance between production and consumption, copper is fundamentally the most threatened metal in the future in terms of potential metal shortage. Manganese nodules contain a considerable percentage of copper as the future metal resource. Therefore, it is necessary to concentrate our effects on developing these resources. This paper introduces our evaluation of R&D progress for the development of manganese nodules. The issue and role of manganese nodules during the difficult period of a potential future metal shortage period is discussed and its prospect outlined. Also, this paper tried to emphasize the necessity of continuous R&D efforts for the commercial development of such mineral resources.