• Title/Summary/Keyword: Rank Normalization

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Quantifying Quality: Research Performance Evaluation in Korean Universities

  • Yang, Kiduk;Lee, Hyekyung
    • Journal of Information Science Theory and Practice
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    • v.6 no.3
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    • pp.45-60
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    • 2018
  • Research performance evaluation in Korean universities follows strict guidelines that specify scoring systems for publication venue categories and formulas for co-authorship credit allocation. To find out how the standards differ across universities and how they differ from bibliometric research evaluation measures, this study analyzed 25 standards from major Korean universities and rankings produced by applying standards and bibliometric measures such as publication and citation counts, normalized impact score, and h-index to the publication data of 195 tenure-track professors of library and information science departments in 35 Korean universities. The study also introduced a novel impact score normalization method to refine the methodology from prior studies. The results showed the university standards to be mostly similar to one another but quite different from citation-driven measures, which suggests the standards are not quite successful in quantifying the quality of research as originally intended.

Adaptive low-resolution palmprint image recognition based on channel attention mechanism and modified deep residual network

  • Xu, Xuebin;Meng, Kan;Xing, Xiaomin;Chen, Chen
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.16 no.3
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    • pp.757-770
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    • 2022
  • Palmprint recognition has drawn increasingly attentions in the past decade due to its uniqueness and reliability. Traditional palmprint recognition methods usually use high-resolution images as the identification basis so that they can achieve relatively high precision. However, high-resolution images mean more computation cost in the recognition process, which usually cannot be guaranteed in mobile computing. Therefore, this paper proposes an improved low-resolution palmprint image recognition method based on residual networks. The main contributions include: 1) We introduce a channel attention mechanism to refactor the extracted feature maps, which can pay more attention to the informative feature maps and suppress the useless ones. 2) The ResStage group structure proposed by us divides the original residual block into three stages, and we stabilize the signal characteristics before each stage by means of BN normalization operation to enhance the feature channel. Comparison experiments are conducted on a public dataset provided by the Hong Kong Polytechnic University. Experimental results show that the proposed method achieve a rank-1 accuracy of 98.17% when tested on low-resolution images with the size of 12dpi, which outperforms all the compared methods obviously.

PPIA, HPRT1, and YWHAZ are suitable reference genes for quantitative polymerase chain reaction assay of the hypothalamic-pituitary-gonadal axis in sows

  • Kim, Hwan-Deuk;Jo, Chan-Hee;Choe, Yong-Ho;Lee, Hyeon-Jeong;Jang, Min;Bae, Seul-Gi;Yun, Sung-Ho;Lee, Sung-Lim;Rho, Gyu-Jin;Kim, Seung-Joon;Lee, Won-Jae
    • Animal Bioscience
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    • v.35 no.12
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    • pp.1850-1859
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    • 2022
  • Objective: The quantitative reverse transcription polymerase chain reaction (qPCR) is the most accurate and reliable technique for analysis of gene expression. Endogenous reference genes (RGs) have been used to normalize qPCR data, although their expression may vary in different tissues and experimental conditions. Verification of the stability of RGs in selected samples is a prerequisite for reliable results. Therefore, we attempted to identify the most stable RGs in the hypothalamic-pituitary-gonadal (HPG) axis in sows. Methods: The cycle threshold values of nine commonly used RGs (18S, HPRT1, GAPDH, RPL4, PPIA, B2M, YWHAZ, ACTB, and SDHA) from HPG axis-related tissues in the domestic sows in the different stages of estrus cycle were analyzed using two RG-finding programs, geNorm and Normfinder, to rank the stability of the pool of RGs. In addition, the effect of the most and least stable RGs was examined by normalization of the target gene, gonadotropin-releasing hormone (GnRH), in the hypothalamus. Results: PPIA, HPRT1, and YWHAZ were the most stable RGs in the HPG axis-related tissues in sows regardless of the stages of estrus cycle. In contrast, traditional RGs, including 18S and ACTB, were found to be the least stable under these experimental conditions. In particular, in the normalization of GnRH expression in the hypothalamus against several stable RGs, PPIA, HPRT1, and YWHAZ, could generate significant (p<0.05) elevation of GnRH in the preovulatory phase compared to the luteal phase, but the traditional RGs with the least stability (18S and ACTB) did not show a significant difference between groups. Conclusion: These results indicate the importance of verifying RG stability prior to commencing research and may contribute to experimental design in the field of animal reproductive physiology as reference data.

The Implement of System on Microarry Classification Using Combination of Signigicant Gene Selection Method (정보력 있는 유전자 선택 방법 조합을 이용한 마이크로어레이 분류 시스템 구현)

  • Park, Su-Young;Jung, Chai-Yeoung
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.12 no.2
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    • pp.315-320
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    • 2008
  • Nowadays, a lot of related data obtained from these research could be given a new present meaning to accomplish the original purpose of the whole research as a human genome project. In such a thread, construction of gene expression analysis system and a basis rank analysis system is being watched newly. Recently, being identified fact that particular sub-class of tumor be related with particular chromosome, microarray started to be used in diagnosis field by doing cancer classification and predication based on gene expression information. In this thesis, we used cDNA microarrays of 3840 genes obtained from neuronal differentiation experiment of cortical stem cells on white mouse with cancer, created system that can extract informative gene list through normalization separately and proposed combination method for selecting more significant genes. And possibility of proposed system and method is verified through experiment. That result is that PC-ED combination represent 98.74% accurate and 0.04% MSE, which show that it improve classification performance than case to experiment after generating gene list using single similarity scale.

Selection and evaluation of reference genes for gene expression using quantitative real-time PCR in Mythimna separata walker (Lepidoptera: Noctuidae)

  • ZHANG, Bai-Zhong;LIU, Jun-Jie;CHEN, Xi-Ling;YUAN, Guo-Hui
    • Entomological Research
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    • v.48 no.5
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    • pp.390-399
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    • 2018
  • In order to precisely assess gene expression levels, the suitable internal reference genes must be served to quantify real-time reverse transcription polymerase chain reaction (RT-qPCR) data. For armyworm, Mythimna separata, which reference genes are suitable for assessing the level of transcriptional expression of target genes have yet to be explored. In this study, eight common reference genes, including ${\beta}$-actin (${\beta}$-ACT), 18 s ribosomal (18S), 28S ribosomal (28S), glyceraldehyde-3-phosphate (GAPDH), elongation fator-alpha ($EF1{\alpha}$), TATA box binding protein (TBP), ribosomal protein L7 (RPL7), and alpha-tubulin (${\alpha}$-TUB) that in different developmental stages, tissues and insecticide treatments of M. separata were evaluated. To further explore whether these genes were suitable to serve as endogenous controls, three software-based approaches (geNorm, BestKeeper, and NormFinder), the delta Ct method, and one web-based comprehensive tool (RefFinder) were employed to analyze and rank the tested genes. The optimal number of reference genes was determined using the geNorm program, and the suitability of particular reference genes was empirically validated according to normalized HSP70, and MsepCYP321A10 gene expression data. We found that the most suitable reference genes for the different experimental conditions. For developmental stages, 28S/RPL7 were the optimal reference genes, both $RPL7/EF1{\alpha}$ were suitable for experiments of different tissues, whereas for insecticide treatments, $28S/{\alpha}-TUB$ were suitable for normalizations of expression data. In addition, $28S/{\alpha}-TUB$ were the suitable reference genes because they have the most stable expression among different developmental stages, tissues and insecticide treatments. Our work is the first report on reference gene selection in M. separata, and might serve as a precedent for future gene expression studies.

3D Model Retrieval Using Sliced Shape Image (단면 형상 영상을 이용한 3차원 모델 검색)

  • Park, Yu-Sin;Seo, Yung-Ho;Yun, Yong-In;Kwon, Jun-Sik;Choi, Jong-Soo
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.45 no.6
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    • pp.27-37
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    • 2008
  • Applications of 3D data increase with advancement of multimedia technique and contents, and it is necessary to manage and to retrieve for 3D data efficiently. In this paper, we propose a new method using the sliced shape which extracts efficiently a feature description for shape-based retrieval of 3D models. Since the feature descriptor of 3D model should be invariant to translation, rotation and scale for its model, normalization of models requires for 3D model retrieval system. This paper uses principal component analysis(PCA) method in order to normalize all the models. The proposed algorithm finds a direction of each axis by the PCA and creates orthogonal n planes in each axis. These planes are orthogonalized with each axis, and are used to extract sliced shape image. Sliced shape image is the 2D plane created by intersecting at between 3D model and these planes. The proposed feature descriptor is a distribution of Euclidean distances from center point of sliced shape image to its outline. A performed evaluation is used for average of the normalize modified retrieval rank(ANMRR) with a standard evaluation from MPEG-7. In our experimental results, we demonstrate that the proposed method is an efficient 3D model retrieval.

The Result of Radiotherapy for Pituitary Adenoma (뇌하수체 선종의 방사선치료 결과)

  • Lee, Hyun-Joo;Yang, Kwang-Mo;Cho, Heung-Lae;Shon, Seung-Chang;Suh, Hyun-Suk
    • Radiation Oncology Journal
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    • v.15 no.4
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    • pp.297-303
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    • 1997
  • Purpose : To evaluate the prognostic factors for disease-free survival and long-term results of radiotherapy for pituitary adenoma. Methods and Materials : The study involved a retrospective review of out-come in a series of 27 patients with pituitary adenoma, between 1984 and 1995 at Paik hospital. The study included 20 patients treated with surgery and postoperative radiotherapy and 7 with radiotherapy alone. The patients were followed for 12-146 months (median : 97 months). Seventeen were men and 10 were women. The numbers of functioning and nonfunctioning pituitary adenorna were 22 and 5 respectively and those of microadenoma and macroadenoma were 4 and 23 respectively. The radiation doses of 5040-5580cGy (median : 5040cGy) were deliverd over 5-7 weeks, using 4MV LINAC. The prognostic factors were analyzed by log-rank test. Results: For radiation therapy alone, the 5YSR was 100% and progression free survival rate was 85.8%, The tumor was controlled in 6/7 (85.8%). For surgery and postoperative radiotherapy. the 5YSR, progression free survival rate and local control rate were 95%, 84.8%, and 89.5% respectively. The parameters of tumor size, hormone secretion, radiation dose. radiotherapy field size were evaluated in a uni- and multivariate analysis and all the factors were not statisticaIty significant (P>0.05). Eleven of 12 (92%) with visual field defect experienced normalization or improvement, and 5 for 7 evaluabie patients with hyperprolactinoma achived normalization in 4 and decrement in S patients. Only 2 patients developed mild degree of Panhypopituitarism. Conclusion: The radiotherapy appears to be effective in controiling clinical symptoms and signs resulting from pituitary adenoma. Local control rate with radiotherapy alone or with surgery and postoperative radiotherauy was comparable. There was a trend toward high recurrence rate in Patients with nonfunctioning or prolactin secretion tumor and larger radiation field sizes.

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