• 제목/요약/키워드: Randomized controlled study

검색결과 2,010건 처리시간 0.026초

메타분석을 통한 뇌졸중 환자의 인지기능에 대한 가상현실 중재 효과 연구 (A Study on the Effect of Virtual Reality Intervention on Cognitive Function in Individuals With Stroke Through Meta-analysis)

  • 권재성
    • 재활치료과학
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    • 제10권3호
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    • pp.7-22
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    • 2021
  • 목적 : 본 연구에서는 뇌졸중 환자의 손상된 인지기능 회복을 위한 가상현실 중재의 효과를 체계적인 문헌고찰과 메타분석을 통하여 검증하고자 하였다. 연구방법 : 체계적 문헌고찰을 위하여 최근 10년 동안의 국내·외 무작위 대조 임상시험 연구들을 대상으로 조사하였다. 검색을 위한 학술 데이터베이스로는, 영어로 작성된 연구의 검색을 위해 PubMed와 MEDLINE, CINAHL을 사용하였고, 국문으로 작성된 연구의 검색을 위해서는 DBpia와 한국학술정보, 스콜라 학지사·교보문고, 학술교육원을 사용하였다. 정보의 추출은 PICO 방식으로 시행하였다. 계량적 메타분석을 위하여, 결과변인의 하위그룹을 전반적인 인지기능, 집중력과 기억력, 실행기능으로 분류하여 결과변인을 합성하였다. 결과 : 최종 9편의 무작위 대조 임상시험이 선정되었고, 참여대상자의 총인원은 실험군이 140명, 대조군이 131명이었다. 효과크기는 랜덤효과모델로 산출하였다. 하위그룹들에 대한 가상현실 중재의 효과크기는 전반적인 인지기능이 0.422(95% CI: 0.101~0.742; p=0.010)로 중간효과크기에 가까웠고, 집중력과 기억력이 0.249(95% CI: -0.107~0.605; p=0.170)로 작은효과크기, 실행기능은 0.666(95% CI: 0.136~1.195; p=0.014)으로 중간효과크기를 나타내었다. 결론 : 가상현실 환경의 다양한 자극과 본 연구의 결과를 고려할 때, 가상현실 중재는 통합적인 인지기능에 대한 중재에 적용되어야 할 것이다. 또한 전통적인 뇌졸중 인지재활 중재와 더불어 추가적인 중재로 활용되는 것이 적절할 것이다.

소양감이 동반된 장미색 비강진 환자의 한방단독치료 보고 (Case Report of the Pityriasis Rosea Patient with Pruritus Treated by Korean Medicine Treatment alone)

  • 이경은;김정필;정선형;안준;정혜인;김경한;장인수;최유민;오용택
    • 대한한의학방제학회지
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    • 제30권1호
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    • pp.27-36
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    • 2022
  • 장미색 비강진 환자에게 방풍통성산(防風通聖散)을 투여하여 증상의 호전과 치료의 안전성을 확인할 수 있었다. 소양감이 심하여 일상에 영향을 받는 등 치료가 필요한 상황이었고, 앞선 스테로이드 치료에는 반응하지 않았지만 한약 복용 후 소양감 및 피부 증상의 뚜렷한 개선을 보였다. 기존의 연구 보고를 근거로 방풍통성산(防風通聖散)이 소염 및 해열작용을 통해 피부 질환에서 유효한 효과를 갖는 것으로 보이고, 이로써 장미색 비강진에서 치료 효과를 발휘한 것으로 사료된다.

두개천골요법의 국내외 임상 연구 동향: 스코핑 리뷰 (Trends in Domestic and International Clinical Research of Craniosacral Therapy: Scoping Review)

  • 곽민제;한윤희;금지혜;박신혁;우현준;하원배;이정한
    • 한방재활의학과학회지
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    • 제32권3호
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    • pp.13-27
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    • 2022
  • Objectives This study investigated the trends in domestic and international clinical research in craniosacral therapy, classified as a type of Chuna manual therapy, and suggested further directions in Korean medicine. Methods This scoping review was performed using the Arksey and O'Malley methodological framework and preferred reporting items as per the preferred reporting items for systematic reviews and meta-analyses extension for scoping reviews checklist. Eight electronic databases (PubMed, EMBASE, Cochrane Library, Koreanstudies Information Service System [KISS], KMBASE, Oriental Medicine Advanced Searching Integrated System [OASIS], Research Information Sharing Service [RISS], ScienceON) were searched to identify articles with the search terms "craniosacral therapy" and "cranial osteopathy" until December 2021. Results Forty-five studies were eligible as per our inclusion criteria. Most research studies (n=44) were conducted in the field of medicine and pharmacy, especially in rehabilitation medicine (n=16). As a result of the study design, randomized controlled trials (n=20) were the most common, and chronic pain (n=9) was the most frequently targeted disease, followed by headache (n=7). Thirty-two studies suggested interventions and 20 studies used Upledger's 10-step protocol. The average duration of craniosacral therapy was 41 min per session, administered 1.4 times per week. Outcome measurements were analyzed and categorized with the examination procedure for the patient. Conclusions This is the first scoping review of craniosacral therapy in Korea, and we believe that our findings could support its utility as Chuna. In the future, more studies should be conducted to establish the evidence of clinical efficacy of craniosacral therapy and develop standard techniques in Korean medicine.

Full-Endoscopic versus Minimally Invasive Lumbar Interbody Fusion for Lumbar Degenerative Diseases : A Systematic Review and Meta-Analysis

  • Son, Seong;Yoo, Byung Rhae;Lee, Sang Gu;Kim, Woo Kyung;Jung, Jong Myung
    • Journal of Korean Neurosurgical Society
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    • 제65권4호
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    • pp.539-548
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    • 2022
  • Objective : Although full-endoscopic lumbar interbody fusion (Endo-LIF) has been tried as the latest alternative technique to minimally invasive transforaminal lumbar interobody fusion (MIS-TLIF) since mid-2010, the evidence is still lacking. We compared the clinical outcome and safety of Endo-LIF to MIS-TLIF for lumbar degenerative disease. Methods : We systematically searched electronic databases, including PubMed, EMBASE, and Cochrane Library to find literature comparing Endo-LIF to MIS-TLIF. The results retrieved were last updated on December 11, 2020. The perioperative outcome included the operation time, blood loss, complication, and hospital stay. The clinical outcomes included Visual analog scale (VAS) of low back pain and leg pain and Oswestry disability index (ODI), and the radiological outcome included pseudoarthosis rate with 12-month minimum follow-up. Results : Four retrospective observational studies and one prospective observational study comprising 423 patients (183 Endo-LIF and 241 MIS-TLIF) were included, and the pooled data analysis revealed low heterogeneity between studies in our review. Baseline characteristics including age and sex were not different between the two groups. Operation time was significantly longer in Endo-LIF (mean difference [MD], 23.220 minutes; 95% confidence interval [CI], 10.669-35.771; p=0.001). However, Endo-LIF resulted in less perioperative blood loss (MD, -144.710 mL; 95% CI, 247.941-41.478; p=0.023). Although VAS back pain at final (MD, -0.120; p=0.586), leg pain within 2 weeks (MD, 0.005; p=0.293), VAS leg pain at final (MD, 0.099; p=0.099), ODI at final (MD, 0.141; p=0.093) were not different, VAS back pain within 2 weeks was more favorable in the Endo-LIF (MD, -1.538; 95% CI, -2.044 to -1.032; p<0.001). On the other hand, no statistically significant group difference in complication rate (relative risk [RR], 0.709; p=0.774), hospital stay (MD, -2.399; p=0.151), and pseudoarthrosis rate (RR, 1.284; p=0.736) were found. Conclusion : Relative to MIS-TLIF, immediate outcomes were favorable in Endo-LIF in terms of blood loss and immediate VAS back pain, although complication rate, mid-term clinical outcomes, and fusion rate were not different. However, the challenges for Endo-LIF include longer operation time which means a difficult learning curve and limited surgical indication which means patient selection bias. Larger-scale, well-designed study with long-term follow-up and randomized controlled trials are needed to confirm and update the results of this systematic review.

관절가동술과 깔창적용이 엉치엉덩관절통증환자의 통증과 골반경사각, 족저압에 미치는 효과: 무작위배정예비임상시험 (Effect of Joint Mobilization and Insole on Pain, Pelvic Angle, and Foot Pressure in Patient with Sacroiliac Joint Pain : A Randomized Controlled Pilot Trial)

  • 임재길
    • 한국엔터테인먼트산업학회논문지
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    • 제14권3호
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    • pp.383-392
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    • 2020
  • 이 연구는 엉치엉덩관절 통증환자에게 관절가동술, 깔창착용 보행훈련, 그리고 관절가동술과 깔창착용 보행훈련 중재를 실시하고 환자의 통증, 골반 각 및 족저압에 대한 효과를 비교하였다. 무작위로 24명의 대상자를 관절가동술군(n=8), 깔창착용보행훈련군(n=8) 또는 관절가동술과 깔창착용보행훈련군(n=8)으로 배정하여, 하루에 30분씩, 일주일에 2번씩 4주 동안 중재하였다. VAS를 사용하여 통증을 평가하고 골반 각도를 Palpation Meter 사용하여 측정하였고, 족저압 (전 / 후비)을 Gateview AFA-50을 사용하여 측정하였다. 모든 측정은 중전·중재 4주 후에 실시하였다. 모든 그룹은 그룹 내 전·후 비교에서 유의한 통증 감소를 보였다(p<.01). 골반 각도에서 관절가동술군은 전방 기울기에서만 통계적으로 개선되었고, 관절가동술과 깔창착용 보해훈련군은 앞쪽 및 뒷쪽기울임 모두에서 통계적으로 유의미한 개선을 보였으며(p<.01), 깔창착용 보행훈련군은 통계적으로 유의한 변화가 없었다(p>.05). 또한 관절가동술과 깔창착용 보행훈련군은 족저압에서 유의한 차이를 나타냈다(p<.01). 모든 중재는 엉치엉덩관절 통증환자의 통증개선에 효과가 있었으며, 관절가동술과함께 깔창착용 보행훈련을 한 군이 골반각도와 족저압에 가장 효과적이었다. 이 연구는 엉치엉덩관절통증이 있는 환자뿐만 아니라 만성 허리통증 및 족저압 입력 문제가 있는 환자의 부상 예방, 자세교정, 그리고 보행훈련을 위한 기초자료가 될 것으로 사료된다.

고혈압의 침치료에 대한 문헌고찰 : 국내 임상 연구를 중심으로 (Effect of Acupuncture on Patients with Hypertension : A Review of Clinical Studies in the Republic of Korea)

  • 정상연;황예채;조승연;이한결;권승원;정우상;문상관;박정미;고창남;박성욱
    • 대한중풍순환신경학회지
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    • 제23권1호
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    • pp.25-40
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    • 2022
  • ■Objectives This study aimed to collect and analyze clinical studies on the significance of acupuncture in the treatment of hypertension among Korean patients. ■Methods Among Korean patients with a blood pressure (BP) of 120 mmHg or higher and a diastolic BP of 80 mmHg or higher, those, treated with acupuncture only, were included. A literature search was conducted through 'Embase', 'Medline', 'Science and Technology Information Integration Service (NDSL)', 'Traditional Korean Knowledge Portal (OASIS)', 'PubMed', and 'Scopus'. The search keywords were (hypertension OR 'blood pressure') AND acupuncture. The papers, published before the day of the search (02. January 2022), were included in this study. ■Results Among the 12 selected papers, seven involved randomized controlled trial (RCT), four before-and-after studies, and one case series. The number of RCTs has increased yearly. The treatment methods used in the studies included needle acupuncture in eight studies, auricular acupuncture in two, pharmacopuncture in one, and si-acupuncture in one. The average numbers of patients enrolled in RCTs, before-and-after studies, and case series were 21.1, 30, and 23 respectively. Six studies were conducted on prehypertensive patients, two on stage 1 hypertension patients, and four on stage 2 hypertension patients. The involved acupoints have been reported to be ST36 in eight papers, LI11 in four papers, and PC6 in three papers. The treatment period lasted for < 1 week in eight studies and 8 weeks in four studies. Acupuncture successfully lowered blood pressure in nine out of 12 studies ■Conclusions Acupuncture is a viable alternative treatment option for prehypertensive patients, who are not taking medications. Additionally, it is also useful in further lowering the BP of patients with stage 1 and stage 2 hypertension in the short term. Large-scale and long-term studies on acupuncture for hypertension should be conducted.

발목관절 가동술과 결합한 전신진동운동이 뇌졸중 환자의 보행 기능과 균형 능력에 미치는 영향: 무작위 대조 예비연구 (Effects of the Whole-body Vibration Exercise Combined with Ankle Joint Mobilization on the Gait Function and Balancing Ability in Stroke Patients: A Preliminary Randomized, Controlled Study)

  • 손수봉;최경욱;김태우;박상영;차용준
    • 대한물리의학회지
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    • 제17권4호
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    • pp.103-111
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    • 2022
  • PURPOSE: This study was performed to investigate the effects of the whole-body vibration exercise combined with ankle joint mobilization on the gait and balancing ability in patients with hemiplegic stroke. METHODS: A total of 19 patients at a rehabilitation hospital who had suffered a hemiplegic stroke were randomly assigned to the experimental group (whole-body vibration exercise combined with ankle joint mobilization, n=10) or control group (whole-body vibration exercise, n=9). All participants underwent 30 min of comprehensive rehabilitation therapy (5 × /week for 6 weeks). Additionally, the experimental group performed the whole body vibration exercise and ankle joint mobilization (15 minutes each, 30 minutes total, 3 × / week for 6 weeks). In the control group, only the whole- body vibration exercise was performed in the same manner and not the ankle joint mobilization. The gait and balancing abilities were measured before and after the 6-week training. RESULTS: Significant improvements were observed in the 10-m walk test, timed up-and-go (TUG) test, center of pressure (COP) path length, and COP path velocity in the experimental group (p < .05). The experimental group showed a larger decrease in the COP path length and velocity than the control group (COP path length, -10.27 mm vs. -3.67 mm, p < .05; COP path velocity, -.33 cm/sec vs. -.13 cm/sec, p < .05, respectively). CONCLUSION: The whole-body vibration exercise combined with ankle joint mobilization could be effective in improving the gait and balancing ability of stroke patients and could also be more effective for improving the static balance ability than the general whole-body vibration exercise alone.

키네시오 테이프의 장력 차이가 젊은 대학생들의 발목 근력, 관절가동범위 및 균형에 미치는 영향 (Effect of tension difference of kinesio tape applied to the tibialis anterior muscle on muscle strength, joint range of motion, and balance of the ankle joint in young college students)

  • 이대훈;김초인;신기하;염유진;김지성;김성호
    • 대한물리치료과학회지
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    • 제29권2호
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    • pp.28-37
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    • 2022
  • Background: The purpose of this study was to investigate the effects of differences in the tension of Kinesio tape applied to the tibialis anterior muscle on muscle strength, joint range of motion and balance of ankle joint in young adults. Design: Randomized Controlled Trial. Methods: 41 young college students participated in this study. And the subjects were allocated randomly to two group. The experimental group had a tension difference (10%G, n=20). And there was no difference in tension in the control group (0%G, n=21). Jtech power track II, goniometer, and Biorescue were used to measure muscle strength, joint range of motion and balance. The paired t-test was performed to examine the differences within the groups before and after taping, and the independent t-test was performed to examine the differences between the groups. Result: 1) As a result of measuring muscle strength of each group, all measurements except 0%G of plantar flexion showed insignificant results. 2) Measurement of joint range of motion each group showed that neither 0%G nor 10%G was significant. 3) As a result of measuring the baladncing ability of each group there was a significant decrease in length, and average speed of the balancing capability (p<.05). 4) Comparisons between groups showed significant differences in the area among balance capability (p<.05). Conclusions: Based on these findings, the tension difference of Kinesio tape applied to the tibialis anterior muscle shows little effect on the muscle strength, range of motion, and balance of ankle joints. Given the current lack of research on the tension of kinesio tapes many studies are needed in the future to establish clear theories.

전립선비대증에 대한 열민구(熱敏灸)의 효과에 관한 체계적 문헌 고찰 (A Systematic Review of effect on Heat-sensitive Moxibustion for Benign Prostatic Hyperplasia)

  • 김민석;주홍민;김민화;박선영;윤영주;박성하
    • 대한한의학회지
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    • 제42권3호
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    • pp.153-164
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    • 2021
  • Objectives: The aim of this study is to investigate the effect of Heat-sensitive Moxibustion on Benign Prostatic Hyperplasia Methods: We searched articles from Academic Journals(CAJ) online databases, Oriental Medicine Advanced Searching Integrated System (OASIS), Searching key words were '前列腺增生', '熱敏灸' and '열민구', '전립선비대'. The search range included randomized controlled trials (RCTs). Among the articles published to 2020, 10 articles were found. After review the title, abstract and original, 3 articles were selected finally to rule out treatment combined with completely different treatments. Result: The Heat-sensitive moxibustion at acupoints in the treatment of Benign prostatic hyperplasia were significantly superior to control group after treatment in the symptoms of patients, IPSS, QOL, PVR and Qmax(P<0.05). The Heat-sensitive moxibustion can significantly reduce the incidence of temporary urinary incontinence after Transurethral resection of the prostate(TURP) and improve life quality and satisfaction of patients(P<0.05). The individualized desensitization saturated time and amount of Heat-sensitive moxibustion is superior effective to general amount and time of traditional moxibustion in the total effective rate, IPSS, Ru and Qmax(P<0.01) for Benign prostatic hyperplasia. Conclusion: Heat sensitive moxibustion directly transfer heat to the source of a disease. So it can be considered as a good treatment for Benign prostate hypertrophy. It was also shown a better effect on BPH compared to traditional moxibustion, According to the thermo principles of tumor, if the tumor cell's death temperature of 43℃ is reached, that can cause tumor degeneration. Therefore I think Heat sensitive moxibustion can be applied to various tumor disease. The results of this study could be applied to clinical treatment of BPH. However, additional large-scale clinical researches should be conducted.