• 제목/요약/키워드: Randomized controlled study

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Electroacupuncture Treatment for Primary Dysmenorrhea: A Review of Randomized Controlled Trials

  • Jeon, Myung Kyu;Park, Jae Eun;Lee, Min Cheol;Kim, Hyeon Jin;Ahn, Jae Young;Shin, Na Young;Nam, Hye Jin;Chae, Go Eun;Jo, Hye Jeong;Kim, Hyun Woo;Lee, Young Jin;Koh, Arha;Kim, Woo Young
    • Journal of Acupuncture Research
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    • 제39권3호
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    • pp.182-189
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    • 2022
  • To evaluate the effectiveness of electroacupuncture treatment for primary dysmenorrhea (PD), a literature review of a randomized controlled trials (RCTs) was performed where electroacupuncture was used as a treatment intervention in patients diagnosed with PD. Relevant clinical studies (N = 226) were retrieved from multiple databases according to the study inclusion/exclusion criteria, and interventions and outcomes were analyzed. As a result of the review, there were 6 RCTs which met the criteria. In all 4 studies that measured pain indicators (visual analog scales), electroacupuncture showed significantly positive changes. In addition, positive changes were observed in most indicators (MMDQ, PGF2a, PGE2, 6-keto PGF1, TXB2, clinical efficacy score, uterine arterial blood flow parameters, and blood viscosity). 2 studies showed that electroacupuncture had a stronger therapeutic effect than NSAIDs. No major side effects were reported. Electroacupuncture may be an effective and safe treatment for PD however, further RCTs are required.

회전근개 질환의 전침 치료에 대한 체계적 문헌고찰 및 메타분석 (Electroacupuncture for Rotator Cuff Disorder: A Systematic Review and Meta-Analysis)

  • 나복연;이상훈;우창훈;김영준
    • 한방재활의학과학회지
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    • 제34권3호
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    • pp.27-41
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    • 2024
  • Objectives This study aims to evaluate the efficacy and safety of electroacupuncture for rotator cuff disorder. Methods We searched nine online databases (PubMed, Embase, Cochrane Library, Chinese Academic Journals, Korean studies Information Service System, Rsearch Information Sharing Service, ScienceON, KMbase, Oriental Medicine Advanced Searching Integrated System) and two related journals up to April 2024 to identify randomized controlled trials that applied electroacupuncture to rotator cuff disorder. Selected studies were analyzed for risk of bias using the Cochrane risk of bias tool, and a meta-analysis was performed with RevMan version 5.4.1. Results Out of 175 studies, eleven randomized controlled trials were selected for final analysis. Most studies showed that electroacupuncture had effect on rotator cuff disorder. In the meta-analysis, electroacupuncture combined with rehabilitation treatment was significantly more effective than rehabilitation treatment alone in improving visual analog scale (p<0.00001). Almost studies did not report any side effects or adverse reactions to electroacupuncture treatment. Conclusions This systematic review suggests that electroacupuncture is an effective treatment for pain management in rotator cuff disorder. However, the lack of adverse effect reporting and a high risk of bias indicate the need for high-quality randomized controlled trials from various countries.

개선된 Randomized Pulse Position PWM기법을 이용한 3상 유도 전동기의 고조파 영향 (Improved Randomized Pulse Position PWM Scheme Based on The three-phase Indui Drive To Reduce the Harmonic Effect)

  • 하상목;한우용;이창구;김병우
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2002년도 하계학술대회 논문집 B
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    • pp.1169-1171
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    • 2002
  • In this paper, RFRPP(Random Frequency Randomized Pulse Position ) PWM for three-phase voltage-controlled inverters is proposed. The LLPWM(Lead-Lag PWM) techinquc is that three switching pulses are located randomly back and forth in each switching interval. But with the restriction of random distribution, the harmonic spectrum cannot be dispersedly and continuously distributed. This paper calculates the duty ratio of the switching pulse firstly. Second, the switching pulses are located randomly in the switching interval. Third, the fixed switching frequency of the space vector modulation is randomly varied. To verify the validity of the proposed technique, simulation study is tried using Matlab/Simulink. When a proposed techniquc is employed, the harmonic spectrum of the inverter output voltagc varies from one cycle to the next and the EMI(Electromagnetic Interference) and resonant vibration are greatly alleviated.

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가상현실기반 재활프로그램이 뇌졸중환자의 균형에 미치는 영향 : 국내연구에 대한 메타분석 (The Effect of Virtual Reality Based Rehabilitation Program on Balance of Patient with Stroke: A Meta-analysis of Studies in Korea)

  • 노정석
    • 대한물리치료과학회지
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    • 제24권1호
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    • pp.59-68
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    • 2017
  • Purpose : The aims of this study was to conduct a systematic literature review with meta-analysis to investigate the effect of virtual reality based rehabilitation program on balance of patient with stroke in Korean studies. Method : The studies for analysis were searched in electronic databases(Research Information Sharing Service; RISS, Korean Studies Information Service; KISS, DBpia, e-articles, National Assembly Library). The key words for search were 'virtual reality', 'stroke', and 'balance' and only randomized controlled trials and clinical controlled trials were included. Of 40 studies identified in the search, 20 studies met the criteria of this study and included in this meta-analysis. Result : The results were as follows: 1) The overall effect size of virtual reality based rehabilitation program was 0.557(95% critical interval; 0.340~0.774). 2) In the analysis of sub-categorical variables, effect size was as follows; the commercial game type(0.621) > virtual environment type(0.335); the dynamic balance measurement(0.750) > static balance measurement(0.226); randomized controlled trial(0.653) > clinical controlled trial(0.275); and thesis type(0.706) > article of journal type(0.339). 3) In the analysis of sub-continuous variables, as time of program(per session) increased, the balance increased(p<0.05). Conclusion : The results of this study showed that virtual reality based rehabilitation program moderately improves the balance of stroke patient. Further studies are recommended to investigate the effect of sub-variables related to virtual reality programs on motor functions of patient with stroke.

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Safety and efficacy of early corticosteroid withdrawal in liver transplant recipients: A randomized controlled trial

  • Jongman Kim;Jae-Won Joh;Kwang-Woong Lee;Dong Lak Choi;Hee-Jung Wang
    • 한국간담췌외과학회지
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    • 제28권2호
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    • pp.238-247
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    • 2024
  • Backgrounds/Aims: Prolonged use of steroids after liver transplantation (LT) significantly increases the risk of diabetes or cardiovascular disease, which can adversely affect patient outcomes. Our study evaluated the effectiveness and safety of early steroid withdrawal within the first year following LT. Methods: This study was conducted as an open-label, multicenter, randomized controlled trial. Liver transplant recipients were randomly assigned to one of the following two groups: Group 1, in which steroids were withdrawn two weeks posttransplantation, and Group 2, in which steroids were withdrawn three months posttransplantation. This study included participants aged 20 to 70 years who were scheduled to undergo a single-organ liver transplant from a living or deceased donor at one of the four participating centers. Results: Between November 2012 and August 2020, 115 patients were selected and randomized into two groups, with 60 in Group 1 and 55 in Group 2. The incidence of new-onset diabetes after transplantation (NODAT) was notably higher in Group 1 (32.4%) than in Group 2 (10.0%) in the per-protocol set. Although biopsy-proven acute rejection, graft failure, and mortality did not occur, the median tacrolimus trough level/dose/weight in Group 1 exceeded that in Group 2. No significant differences in safety parameters, such as infection and recurrence of hepatocellular carcinoma, were observed between the two groups. Conclusions: The present study did not find a significant reduction in the incidence of NODAT in the early steroid withdrawal group. Our study suggests that steroid withdrawal three months posttransplantation is a standard and safe immunosuppressive strategy for LT patients.

CAJ 검색을 통해 살펴 본 중국에서의 역류성 식도질환 침구치료 임상연구 동향에 대한 고찰 (A Review on Clinical Studies of the Acupuncture and Moxibustion Therapy for Gastroesophageal Reflux Disease in China by Searching CAJ)

  • 강세영
    • Korean Journal of Acupuncture
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    • 제32권1호
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    • pp.1-12
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    • 2015
  • Objectives : The purpose of this study was to review the acupuncture and moxibustion therapy for gastroesophageal reflux disease(GERD) in China. Methods : The literatures were searched using the database-China Academic Journals(CAJ)(~2015.1.). Clinical studies of acupuncture and moxibustion therapy for GERD such as randomized controlled trial(RCT), non-randomized controlled trial(NRCT), case series, or case report were included. Results : Thirty studies met our inclusion criteria: 24 RCTs, 4 NRCTs, 1 case series, 1 case report. Various kinds of treatment such as body acupuncture, abdominal acupuncture, acupuncture therapy with finger on back-shu point, electroacupuncture, acupoint injection, auricular acupuncture, and moxibustion were used in the clinical studies. The treatment groups take herbal medicines at the same time in 16 studies, and proton pump inhibitor(PPI) and histamine 2 receptor antagonist were used as a comparative treatment in the most of studies. Acupuncture or moxibustion treatments were done daily or 2~3 times a week for 5 days~18 weeks. All of studies reported higher effective rate in the acupuncture or moxibustion treatment group compared to the western medication control group. Conclusions : The results of this study could be used for the future practice and the clinical research about the acupuncture and moxibustion therapy for GERD.

고혈압 침치료에 관한 최근 연구 동향 고찰 - Pubmed와 국내 논문 중심으로 - (A Review of Recent Acupuncture Treatment for Hypertension - PubMed and Domestic Studies)

  • 김승연;원재호;이인
    • 대한한방내과학회지
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    • 제41권1호
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    • pp.29-43
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    • 2020
  • Objectives: The purpose of this study was to summarize current research trends and results regarding acupuncture treatment for hypertension. Methods: Articles published from 2009 to 2019 were searched on domestic databases (OASIS, NDSL, RISS) and PubMed using the keywords 'Hypertension', 'Hypertensive', 'Acupuncture', 'EA' (electroacupuncture), 'Autonomic nervous system', 'ANS', 'CVD' (cardiovascular disease), '고혈압', '침', '전침', and '자율신경계'. The studies were analyzed according to the year, type of study (domestic or foreign articles, nationality of the first author), acupuncture type for human and animal studies, BP (blood pressure) measurement, and acupuncture intervention. Results: In total, 21 articles were selected. There were 8 randomized controlled trials (RCTs), 3 non-randomized controlled trials (nRCTs), 2 before-after studies, 1 case series, and 7 animal studies. Manual acupuncture (11 articles) was most frequently used, and ST36 (足三里) was most frequently used in human studies. In 18 of 21 articles, acupuncture was reported as effective in lowering systolic blood pressure (SBP) or diastolic blood pressure (DBP) in hypertensive patients. Conclusions: Acupuncture treatment for hypertension is deemed useful. Further studies are necessary for application of acupuncture therapy in clinical practice.

The effects of treadmill training on dynamic balance and gait function in stroke patients: a pilot randomized controlled trial

  • Chung, Eun Jung;Lee, Byounghee
    • Physical Therapy Rehabilitation Science
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    • 제2권1호
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    • pp.39-43
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    • 2013
  • Objective: The objective of this study is to investigate the effect of treadmill gait trainig on dynamic balance and gait functions in stroke patients. Design: Randomized, double-blind, controlled pilot study. Methods: Four subjects following first stroke participated in this study. They were divided randomly into the treadmill gait trainig group (TM group) (n=2) and the control group (n=2). Subjects in both groups received general training five times per week. Subjects in the TM group practiced an additional treadmill gait trainig program that consisted of 60 minutes, three times per week, during a period of four weeks. Timed up and go test (dynamic balance) and the GAITRite test (gait function) were evaluated before and after the intervention. Results: In dynamic balance (timed up and go test), the TM group (-14.235 sec) showed a greater decrease than the control group (-13.585 sec). In gait functions, the TM group showed a greater increase in gait speed (12.8 cm/s vs. 10.15 cm/s), step-length (5.825 cm vs. 3.735 cm), and stride-length (5.005 cm vs. 1.55 cm) than the control group. Conclusions: The treadmill gait trainig improved dynamic balance and gait functions. Further research is needed in order to confirm the generalization of these findings and to identify which stroke patients might benefit from treadmill gait trainig.

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The effects of an additional weight aquatic exercise program on balance and lower extremity strength in persons with stroke: randomized controlled study

  • Park, Jaeho;Chung, Yijung
    • Physical Therapy Rehabilitation Science
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    • 제7권1호
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    • pp.6-12
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    • 2018
  • Objective: The purpose of this study was to investigate the effects of an additional weight aquatic exercise program on the balance and lower extremity strength on aquatic environment in persons with stroke. Design: Randomized controlled trial. Methods: All subjects were randomly divided into three groups where thirteen subjects were in the additional weight aquatic exercise group, twelve subjects in the aquatic exercise group, and fifteen subjects in the control group. Subjects received a graded aquatic exercise program for 30 minutes, with 3 sessions per week for 6 weeks, and subjects in all groups received conventional physical therapy. All subjects were assessed with the Medical Research Council (MRC), the Berg Balance scale (BBS), Timed Up and Go test (TUG), and 10-meter walk test (10MWT) pre and post intervention. Results: The MRC, BBS, TUG, and 10MWT scores significantly improved post-intervention (p<0.05), and the control group also had significantly improved in all areas post-treatment (p<0.05). In addition, it has been confirmed that the additional weight aquatic exercise group had significantly improved in MRC, BBS, and TUG scores compared with the aquatic exercise and control group (p<0.05). Conclusions: The findings of this study suggested that the additional weight aquatic exercise program improves lower extremity and balance in persons with stroke.

후방 보행훈련이 급성기 뇌졸중 환자의 균형, 균형 자신감, 낙상 효능에 미치는 영향: 무작위 대조군 예비연구 (The effect of backward walking training on balance, balance confidence and falls efficacy in patients with acute stroke: A pilot randomized controlled trial)

  • 정경만
    • 대한물리치료과학회지
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    • 제28권2호
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    • pp.1-9
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    • 2021
  • Background: The requirements for postural and motor control in backward walking training (BWT) may improve balance and walking speed in patients with acute stroke. The aim of this study was to analyze the effect of BWT on balance, balance confidence, and fall efficacy in this population. Design: Randomized controlled pilot trial. Methods: This study included 14 subjects with acute stroke (onset of illness less than one month). They were randomly allocated to a BWT (n=7) or forward walking training (n=7) group and observed five times in a week for a period of two weeks. Measurements were taken before and after the experiment using the Berg balance scale (BBS), Activities-specific balance confidence scale (ABC), and Fall efficacy scale (FES). Results: The BBS, ABC and FES scores obtained in both groups after the experiment were significantly higher than those before the experiment (p<0.05). In addition, the BBS, ABC, and FES scores in the experimental group were significantly higher than those in the control group (p<0.05). Conclusion: These findings indicate that BWT improved balance and balance confidence and decreased the risks of fall in patients with acute stroke. Further study is needed to better understand the effects of backward walking in acute stroke patients.