• 제목/요약/키워드: Randomized allocation

검색결과 55건 처리시간 0.023초

허리 불안정성이 있는 허리통증 환자에게 실시한 자가-복합 운동프로그램이 통증과 기능, 심리사회적, 균형 능력 그리고 배가로근에 미치는 효과 (Effect of Self-Complex Exercise Program on Pain, Function, Psychosocial, Balance Ability, and TrA Muscle in Patients with Lumbar Instability: A Randomized Controlled Trial)

  • 윤종혁;정대근;박삼호
    • 대한통합의학회지
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    • 제10권2호
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    • pp.73-83
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    • 2022
  • Purpose : Low back pain (LBP) is reported as a risk of experiencing musculoskeletal disorders due to muscle stiffness and hypokinetics. The lumbar spine in an unstable state causes imbalance and lumbar instability. Therefore, This study examined the effects of lumbar stabilization exercise and self-complex exercise program on pain, function, psychosocial level, static balance ability, and transverse abdominal muscle (TrA) thickness and contraction ratio in patients with lumbar instability. Methods : The design of this is a randomized controlled trial (RCT). Twenty-six LBP patients participated in this study. Screening tests were performed and assigned to the experimental group (n=13) and control group (n=13) using a random allocation program. Both groups underwent a lumbar stabilization exercise program. In addition, the experimental group implemented the self-complex exercise program. All interventions were applied three times per week for four weeks. The quadruple visual analog (QVAS), the Korean version of the Oswestry disability index (K-ODI), Korean version of fear-avoidance belief questionnaire (FABQ), static balance ability, TrA thickness, and contraction ratio were compared to evaluate the effect on intervention. Statistical significance was set at 𝛼=.05. Results : Both groups showed significant differences before and after the intervention in QVAS, K-ODI, FABQ, static balance ability, and TrA thickness in contraction (p<.05). In addition, significant differences in K-ODI and FABQ were observed between the experimental group and control group (p<.05). Conclusion : A lumbar stabilization exercise and self-complex exercise program resulted in reduced dysfunctions, psychosocial stability in patients with lumbar instability. Therefore, Lumbar stabilization exercise and self-complex exercise program for patients with lumbar instability are effective method with clinical significance in improving the function and psychosocial stability.

Effectiveness of low-level laser therapy in facilitating maxillary expansion using bone-borne hyrax expander: A randomized clinical trial

  • Abdelwassie, Sara Hassan;Kaddah, Mohammed Amgad;El-Dakroury, Amr Emad;El-Boghdady, Dalia;Abd El-Ghafour, Mohamed;Seifeldin, Nouran Fouad
    • 대한치과교정학회지
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    • 제52권6호
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    • pp.399-411
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    • 2022
  • Objective: The objective of this randomized clinical trial was to study the skeletal and dental effects of low-level laser therapy (LLLT) along with a miniscrew-assisted expander (Hyrax) after six months of retention. Methods: After sequence generation, concealed allocation, and implementation, 24 female patients were randomly divided (1:1) into two-groups: bone-borne rapid palatal expansion (BBE) without LLLT (n = 12) and BBE with LLLT (n = 12). Eligibility criteria included female patients aged 10-13 years old with bilateral posterior crossbites. Intraoral and extraoral photographs, cone-beam computed tomography images, and digital study models were obtained before expansion and six months after retention. The 7 mm Hyrax appliance was anchored to four palatal mini-screws, which were activated twice daily for 15 days, then locked and kept in place as a retainer. LLLT was performed in the laser group during expansion and retention, according to the guidelines provided. Results: The records of 24 patients were analyzed. According to the post-retention measurements, both groups showed a significant increase in nasal and maxillary widths and total facial height. In the laser group, the Sella-Nasion-Point A and Point A-Nasion-Point B angles and the interpremolar apical distance were significantly increased. Conclusions: Within the limitations of this study, the results suggest that the parameters and protocol of LLLT do not clinically affect the efficiency of BBE in prepubertal and pubertal patients.

Periotome versus piezotome as an aid for atraumatic extraction: a randomized controlled trial

  • Mohammed Abdullah, Alraqibah;Jingade Krishnojirao Dayashankara, Rao;Bader Massad, Alharbi
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제48권6호
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    • pp.356-362
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    • 2022
  • Objectives: A single-blinded randomized controlled trial was designed to compare and evaluate the effectiveness of the periotome and piezotome as aids for atraumatic extraction and its sequalae. Materials and Methods: The study sample comprised 48 teeth, equally allotted to the piezotome or periotome groups by random allocation, in participants aged 19-62 years. All samples in both groups had either complete tooth structure or intact roots without crowns and had mobility ≤grade II. Clinical parameters of operative duration, presence or absence of gingival laceration, reported operative and postoperative pain, and intake of analgesics following extraction were recorded. IBM SPSS software package version 22 was used for data entry and analysis. Results: The mean operation time was significantly (P≤0.05) longer in the piezotome group than in the periotome group. However, fewer gingival lacerations were observed with use of a piezotome than with a periotome, although no significant difference was observed. The piezotome group reported significantly (P≤0.05) higher visual analog scale (VAS) pain scores during the procedure and non-significantly higher scores thereafter until the third postoperative day. In the piezotome group, the dosage of analgesic was higher, although the periotome group had a higher percentage of participants who used analgesics postoperatively; however, these differences were not statistically significant. Conclusion: The present clinical trial favors the use of periotome over piezotome for atraumatic extraction due to shorter operating time, lower postoperative VAS pain scores, and lower dosage of analgesics despite the superior ability of the piezotome to prevent gingival laceration.

Effectiveness of laser-engineered copper-nickel titanium versus superelastic nickel-titanium aligning archwires: A randomized clinical trial

  • Omar Khairullah Ahmed;Ammar Salim Kadhum
    • 대한치과교정학회지
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    • 제54권1호
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    • pp.16-25
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    • 2024
  • Objective: To compare the effectiveness of laser-engineered copper-nickel titanium (SmartArch) and superelastic nickel-titanium (SENT) archwires in aligning teeth and inducing root resorption and pain experienced by patients. Methods: Two-arm parallel groups with a 1:1 allocation ratio were used. The participants were patients aged 11.5 years and older with 5-9 mm of mandibular anterior crowding who were indicated for non-extraction treatment. The primary outcome was alignment effectiveness, assessed using Little's irregularity index (LII) over 16 weeks with a single wire (0.016-inch) in the SmartArch group and 2 wires (0.014- and 0.018-inch) in the SENT group (8 weeks each). Secondary outcomes included root resorption evaluated by pre- and post-intervention periapical radiographs and pain levels recorded by the participants during the first week. Results: A total of 40 participants were randomly allocated into 2 groups; 33 completed the study and were analyzed (16 in the SmartArch group and 17 in the SENT group, aged 16.97 ± 4.05 years). The total LII decrease for the SmartArch and SENT groups was 5.63 mm and 5.29 mm, respectively, which was neither statistically nor clinically significant. Root resorption was not significantly different between the groups. The difference in pain levels was not statistically significant for the first 5 days following wire placement; however, there was a significant difference favoring the SENT group in the final 2 days. Conclusions: SmartArch and SENT archwires were similarly effective during the alignment phase of orthodontic treatment. Root resorption should be observed throughout the treatment with either wire. SmartArch wires demonstrated higher pain perception than SENT wires.

층화 및 층화 이표본 조건부 무관질문모형 (A Stratified and Two Sample Stratified Conditional Unrelated Question Model)

  • 이기성
    • Journal of the Korean Data Analysis Society
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    • 제20권6호
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    • pp.2883-2893
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    • 2018
  • 본 논문에서는 모집단이 층으로 구성되어 있고 얻고자 하는 속성이 민감할 때, 덜 민감한 속성 B와 강요응답으로 구성되어 있는 확률장치를 통해 "예"라고 응답한 사람들에게만 민감한 속성 A 와 무관한 속성 Y를 포함하고 있는 Greenberg et al.(1969)의 무관질문모형을 사용하도록 하여 모집단이 층화된 경우 층화추정을 위한 층화 조건부 무관질문모형을 제안하였다. 그리고 제안한 층화 조건부 무관질문모형에서 각 층에 표본을 배분할 때 비례배분과 최적배분 문제를 다루었다. 또한 층화 조건부 무관질문모형을 무관한 속성이 미지인 경우 두 개의 독립표본을 이용하는 층화 이표본 조건부 무관질문모형으로 확장하였으며, 제안한 층화 이표본 조건부 무관질문모형의 두 번째 단계에서 사용되는 h층의 표본의 크기에 대한 최적값을 도출하여 최소분산을 구하였다. 마지막으로 층화 조건부 무관질문모형이 층화 무관질문모형과 층화 Carr et al.(1982)의 모형보다 효율적이 되는 조건을 제시하여 일정한 조건하에서 제안한 모형이 기존 모형들보다 효율적임을 보였으며, 제안한 층화 조건부 무관질문모형이 ${\pi}_{h2}$ 값이 작고 ${\pi}_{hy}$ 값이 작을수록 층화 Carr et al.(1982)의 모형보다 효율적임을 수치적으로 보였다.

Effect of Pulsed Electromagnetic Field Treatment on Alleviation of Lumbar Myalgia; A Single Center, Randomized, Double-blind, Sham-controlled Pilot Trial Study

  • Park, Won-Hyung;Sun, Seung-Ho;Lee, Sun-Gu;Kang, Byoung-Kab;Lee, Jong-Soo;Hwang, Do-Guwn;Cha, Yun-Yeop
    • Journal of Magnetics
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    • 제19권2호
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    • pp.161-169
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    • 2014
  • The aim of this study is to investigate the efficacy of pulsed electromagnetic field (PEMF) on the alleviation of lumbar myalgia. This is a randomized, real-sham, double blind pilot study. 38 patients were divided into the PEMF group and the Sham group, each of which was composed of 19 patients (1 patient dropped out in the Sham group) of randomized allocation. The PEMF group was treated by using the PEMF device and the Sham group by using a sham device on the lumbar muscle and acupuncture points, three times a week for a total of two weeks. Evaluations of Visual Analogue Scale for bothersomeness (VASB), Visual Analogue Scale for pain intensity (VASP), Oswestry Disability Index (ODI), 36-Item Short Form Health Survey Instrument (SF-36), EuroQol-5Dimension (EQ-5D), Beck's Depression Inventory (BDI) and Roland-Morris Disability Questionnaire (RMDQ), etc. before and 1 week after treatment were carried out. The primary outcome measure was the VASB, measured 1 week after the end of the pulsed electromagnetic therapy. VASB scores for the PEMF group changed by $-2.06{\pm}2.12$ from the baseline, and that for the Sham group changed by $-0.52{\pm}0.82$ (p < 0.05). VASP scores for the PEMF group were reduced by $-2.10{\pm}2.12$ from the base line, and that for the Sham group was reduced by $-0.53{\pm}1.50$ (p < 0.05). PEMF group showed significant improvements in all VASB, VASP, ODI, SF-36, EQ-5D, BDI and RMDQ scores, while the Sham group showed significant improvements in all scores, except the VASP score. However, the VASB, VASP and RMDQ scores of the PEMF group were much lower than those of the Sham group. The two groups showed no significant difference in ODI, SF-36, EQ-5D and BDI. This study demonstrates the effectiveness of PEMF treatment for alleviating lumbar myalgia.

No-Touch vs. Conventional Radiofrequency Ablation Using Twin Internally Cooled Wet Electrodes for Small Hepatocellular Carcinomas: A Randomized Prospective Comparative Study

  • Yun Seok Suh;Jae Won Choi;Jeong Hee Yoon;Dong Ho Lee;Yoon Jun Kim;Jeong Hoon Lee;Su Jong Yu;Eun Ju Cho;Jung Hwan Yoon;Jeong Min Lee
    • Korean Journal of Radiology
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    • 제22권12호
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    • pp.1974-1984
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    • 2021
  • Objective: This study aimed to compare the efficacy between no-touch (NT) radiofrequency ablation (RFA) and conventional RFA using twin internally cooled wet (TICW) electrodes in the bipolar mode for the treatment of small hepatocellular carcinomas (HCC). Materials and Methods: In this single-center, two-arm, parallel-group, prospective randomized controlled study, we performed a 1:1 random allocation of eligible patients with HCCs to receive NT-RFA or conventional RFA between October 2016 and September 2018. The primary endpoint was the cumulative local tumor progression (LTP) rate after RFA. Secondary endpoints included technical conversion rates of NT-RFA, intrahepatic distance recurrence, extrahepatic metastasis, technical parameters, technical efficacy, and rates of complications. Cumulative LTP rates were analyzed using Kaplan-Meier analysis and the Cox proportional hazard regression model. Considering conversion cases from NT-RFA to conventional RFA, intention-to-treat and as-treated analyses were performed. Results: Enrolled patients were randomly assigned to the NT-RFA group (37 patients with 38 HCCs) or the conventional RFA group (36 patients with 38 HCCs). Among the NT-RFA group patients, conversion to conventional RFA occurred in four patients (10.8%, 4/37). According to intention-to-treat analysis, both 1- and 3-year cumulative LTP rates were 5.6%, in the NT-RFA group, and they were 11.8% and 21.3%, respectively, in the conventional RFA group (p = 0.073, log-rank). In the as-treated analysis, LTP rates at 1 year and 3 years were 0% and 0%, respectively, in the NT-RFA group sand 15.6% and 24.5%, respectively, in the conventional RFA group (p = 0.004, log-rank). In as-treated analysis using multivariable Cox regression analysis, RFA type was the only significant predictive factor for LTP (hazard ratio = 0.061 with conventional RFA as the reference, 95% confidence interval = 0.000-0.497; p = 0.004). There were no significant differences in the procedure characteristics between the two groups. No procedure-related deaths or major complications were observed. Conclusion: NT-RFA using TICW electrodes in bipolar mode demonstrated significantly lower cumulative LTP rates than conventional RFA for small HCCs, which warrants a larger study for further confirmation.

전신진동운동이 노인의 균형, 근력 및 낙상효능감에 미치는 영향 (The Effect of Whole-Body Vibration Exercise on Balance, Muscle Strength and Falls Efficacy in the Elderly)

  • 김영민;박진환
    • 대한물리의학회지
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    • 제12권4호
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    • pp.61-71
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    • 2017
  • PURPOSE: The purpose of the present study was to investigate the effects of whole body vibration exercise on balance, muscle strength and falls efficacy in the elderly. METHODS: In this blinded randomized allocation study, 27 elderly were assigned to a whole-body vibration exercise group (n=14), consisting of 25 min structured exercises for 2 days per week for 6 weeks and a control group (n=13) performing the same program without vibration. At baseline and after the 6-week intervention, balance was measured using the Korean version of the Berg balance scale (K-BBS), timed up and go (TUG) test and functional reach test (FRT). Muscle strength was determined using the 30-s chair stand test (CST). Fear of falling was assessed using the Korean version of falls efficacy scale (K-FES). Paired t-test and independent t-test were used for within and between group comparisons, respectively. RESULTS: After the intervention, the experimental group showed significantly higher changes in all the parameters (K-BBS score, TUG test, CST, K-FES score) (p<.05) compared with the control group. However, there was no significant change in all parameters in the control group (p>.05). CONCLUSION: The whole-body vibration exercise program may be helpful to improve balance, mobility, muscle performance and fear of falling in the elderly.

Effect of dietary ractopamine supplementation on growth performance, meat quality and fecal score in finishing pigs

  • Hoque, Md-Raihanul;Im, Yu-Mi;Kim, In Ho
    • 농업과학연구
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    • 제47권4호
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    • pp.707-715
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    • 2020
  • An experiment was designed to assess ractopamine supplementation on growth, meat quality and carcass, and fecal scores of pigs. The 96 crossbred pigs ([Yorkshire× Landrace] × Duroc) had an average body weight of 72.8 ± 2.5 kg. Randomized allocation was followed in the allotment of the pigs according to their body weight into 1 of 2 dietary treatments: 1) CON, basal diet and 2) RAC (ractopamine hydrochloride), CON + 1% ractopamine with 12 replication pens per treatment including equal numbers of barrows (2) and gilts (2) per pen. At the end of the experiment, the lean meat percentage was higher (p < 0.05) for the RAC group compared to the CON group. Dietary ractopamine supplementation did not influence (p > 0.05) the growth performance and fecal score throughout the experimental period. In regard to sensory evaluation, higher (p < 0.05) scores for color and firmness were observed in the RAC group than in the CON group. Drip loss (p < 0.05) was higher in the ractopamine fed diet group compared to the control diet group at day 1. Additionally, longissimus muscle was improved (p < 0.05) in the ractopamine treated diet group than in the control diet group. In conclusion, in the early stage, ractopamine supplementation may not influence the growth performance, but it improves the leanness in the meat of finishing pigs.

Effect of Vibration Exercise Application on the Trunk Muscle Thickness in Children with Spastic Cerebral Palsy

  • Mun, Dal-Ju;Park, Jae-Chul;Oh, Hyun-Ju
    • The Journal of Korean Physical Therapy
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    • 제34권2호
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    • pp.68-72
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    • 2022
  • Purpose: This study examined the effect of vibration exercise on the thickness of the oblique extrinsic, oblique abdominal, and biceps muscles, which are trunk muscles, targeting children with spastic cerebral palsy. Methods: The participants in this study were 20 children (8 male and 12 female) with cerebral palsy aged 5-10 years. They were classified into two groups using a randomized allocation method, and the trunk muscle thickness was measured using an ultrasound-imaging device before and six weeks after the experiment. A paired t-test was used for the within-group changes, and an independent t-test was used for the inter-group changes. The significance level was set to α=0.05. Results: There was a significant increase in the inter-group change in the experimental group and control group in the intra-group change in the external oblique muscle and internal oblique muscle. After six weeks, there was a significant increase in the experimental group compared to the control group. Conclusion: Vibration exercise had a positive effect on the trunk muscle thickness of children with cerebral palsy. Vibration exercise produced a significant difference in the changes in the trunk muscle thickness in children with cerebral palsy compared to no vibration exercise. These results may provide basic data for future research and as a training method for strengthening the trunk muscles in clinical trials.