• Title/Summary/Keyword: Radiation technique

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Understanding on MR Perfusion Imaging Using First Pass Technique in Moyamoya Diseases (Moyamoya 질환에서 1차 통과기법을 이용한 자기공명관류영상의 이해)

  • Ryu, Young-Hwan;Goo, Eun-Hoe;Jung, Jae-Eun;Dong, Kyung-Rae;Choi, Sung-Hyun;Lee, Jae-Seung
    • Korean Journal of Digital Imaging in Medicine
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    • v.12 no.1
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    • pp.27-31
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    • 2010
  • The purpose of this study was to investigated the usefulness of MR perfusion image comparing with SPECT image. A total of pediatric 30 patients(average age : 7.8) with Moyamoya disease were performed MR Perfusion with 32 channel body coil at 3T from March 01, 2010 to June 10, 2010. The MRI sequences and parameters were as followed : gradient Echo-planar imaging(EPI), TR/TE : 2000ms/50ms, FA : $90^{\circ}$, FOV : $240{\times}240$, Matrix : $128{\times}128$, Thickness : 5mm, Gap : 1.5mm. Images were obtained contrast agent administrated at a rate of 1mL/sec after scan start 10s with a total of slice 1000 images(50 phase/1 slice). It was measured with visual color image and digitize data using MRDx software(IDL version 6.2) and also, it was compared of measurement with values of normal and abnormal ratio to analyze hemodynamic change, and a comparison between perfusion MR with technique using Warm Color at SPECT examination. On MR perfusion examination, the color images from abnormal region to the red collar with rCBV(relative cerebral blood volume) and rCBF(relative cerebral blood flow) caused by increase cerebral blood flow with brain vascular occlusion in surrounding collateral circulation advancement, the blood speed relatively was depicted slowly with blue in MTT(Mean Transit Time) and TTP(Time to Peak) images. The region which was visible abnormally from MR perfusion examination visually were detected as comparison with the same SPECT examination region, would be able to confirm the identical results in MMD(Moyamoya disease)judgments. Hymo-dynamic change in MR perfusion examination produced by increase and delay cerebral blood flow. This change with digitize data and being color imaging makes enable to distinguish between normal and abnormal area. Relatively, MR perfusion examination compared with SPECT examination could bring an excellent image with spatial resolution without radiation expose.

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Study on Image Composition and the Manufacturing Techniques of Bamboo Mudguard with Gilt-bronze Openwork from Cheonmachong Ancient Tomb (천마총 출토 죽제 천마문 금동장식 장니의 화면구도와 제작기법에 관한 연구)

  • Lee, Seung Ryul;Shin, Yong Bi;Jung, Won Seob
    • Journal of Conservation Science
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    • v.32 no.2
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    • pp.141-154
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    • 2016
  • The gilt-bronze decorated bamboo mudguards with heavenly horse design excavated in 1973 at Cheonma Tomb of Shilla are the unprecedented relics in Korean history as it has its original structure. Although the bamboo mudguards were excavated in not only Cheonma Tomb, but also in Geumgwanchong and Geumryeongchong, all of them remains into pieces. In addition, there are no exact data related with its structure and manufacturing technique. The report deals with the manufacturing technique of the bamboo mudguards with heavenly horse design excavated in Cheonma Tomb through the naked eye's observation, X-Ray Fluorescence, and Transmission X-rays analysis etc. Bamboo mudguards basically have the three divided structure with central-focus structure of a radiation style. And the mudguards consists of Bratticing gilt-bronze, fabric, and bamboo plates together, as ornamental fringe of 4 plates. The surface of the gilt bronze plates was decorated with a variety of workmanship and pendant. Bamboo plates have a waved pattern by using about three hundred bamboo bark. Two types of textiles were mainly found in the textile plates, and the leather were partially found. In order to combine all plates together, gilt-bronze bottonhead, pendant decoration, and ornamental fringe were used. It would be helpful to study bamboo mudguards during 5th-6th centuries in Shilla period and basis investigations of Geumgwanchong and Geumryeongchong excavations.

Study on Analysis Technique Comparison and Evaluation of High Thermal Conductivity Concrete with Magnetite Aggregates and Steel Powder (자철광 및 철분말을 혼입한 고열전도 콘크리트의 열전도 평가 및 해석기법 비교에 대한 연구)

  • Lee, Hack-Soo;Kim, Min-Kyu;Kwon, Seung-Jun
    • Journal of the Korea Concrete Institute
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    • v.26 no.3
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    • pp.315-321
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    • 2014
  • Concrete as a construction material is widely used in nuclear vessel and plant for excellent radiation shielding. However the isolation characteristics in concrete may affect adversely in the case of fire and melt-down in nuclear vessel since temperature cooling down is very difficult from outside. This study is for development of high thermal conductive concrete, and its mechanical and thermal properties are evaluated. Magnetite aggregates with volume ratio of 42.3% (maximum) and steel powder of 1.5% are replaced with normal aggregates and thermal properties are evaluated. Thermal conductivity little increases by 30% addition of magnetite but rapidly increases afterwards. Finally thermal conductivity is magnified to 2.5 times in the case of 42.3% addition of magnetite. Steel powder has a positive effect on high thermal conduction to 106~113%. Several models for thermal conduction like ACI, DEMM, and MEM are compared with test results and they are verified to reasonably predict the thermal conductivity with increasing addition of magnetite aggregates and steel powder.

Knockdown of Archvillin by siRNA Inhibits Myofibril Assembly in Cultured Skeletal Myoblast

  • Lee, Yeong-Mi;Kim, Hyun-Suk;Choi, Jun-Hyuk;Choi, Jae-Kyoung;Joo, Young-Mi;Ahn, Seung-Ju;Min, Byung-In;Kim, Chong-Rak
    • Biomedical Science Letters
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    • v.13 no.4
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    • pp.251-261
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    • 2007
  • A myofiber of skeletal muscle is composed of myofibrils, sarcolemma (plasma membrane), and constameres, which anchor the myofibrils to the sarcolemma. Achvillin is a recently identified F-actin binding muscle protein, co-isolates with dystrophin and caveolin-3 in low-density sarcolemma of striated muscle, and colocalizes with dystrophin at costameres, the specialized adhesion sites in muscle. Archvillin also binds to nebulin and localizes at myofibrillar Z-discs, the lateral boundaries of the sarcomere in muscle. However other roles of archvillin on the dynamics of myofibrillogenesis remain to be defined. The goal of this study is, by using siRNA-mediated gene silencing technique, to investigate the effect of archvillin on the dynamics of myofibrillogenesis in cell culture of a mouse skeletal myogenic cell line (C2C12), where presumptive myoblasts withdraw from the cell cycle, fuse, undergo de novo myofibrillogenesis, and differentiate into mature myotubes. The roles of archvillin in the assembly and maintenance of myofibril and during the progression of myofibrillogenesis induced in skeletal myoblast following gene silencing in the cell culture were investigated. Fluorescence microscopy demonstrated that the distribution of archvillin was changed along the course of myofibril assembly with nebulin, vinculin and F-actin and then located at Z-lines with nebulin. Fluorescence microscopy demonstrated that knockdown of mouse archvillin expression led to an impaired assembly of new myofibrillar clusters and delayed fusion and myofibrillogenesis although the mouse archvillin siRNA did not affect those expressions of archvillin binding proteins, such as nebulin and F-actin. This result is corresponded with that of RT-PCR and western blots. When the perturbed archvillin was rescued by co-transfection with GFP or Red tagged human archvillin construct, the inhibited cell fusion and myotube formation was recovered. By using siRNA technique, archvillin was found to be involved in early stage of myofibrillogenesis. Therefore, the current data suggest the idea that archvillin plays critical roles on cell fusion and dynamic myofibril assembly.

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Inflammation Scan Using $^{99m}Tc-HMPAO$ Labelled Leukocytes ($^{99m}Tc-HMPAO$를 이용한 자가백혈구표지 및 그를 이용한 염증병소의 스캔)

  • Yang, Woo-Jin;Chung, Soo-Kyo;Shinn, Kyung-Sub;Bahk, Yong-Whee;Kim, Hoon-Kyo
    • The Korean Journal of Nuclear Medicine
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    • v.23 no.2
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    • pp.219-223
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    • 1989
  • Inflammation scan using radiolabelled leukocytes has high sensitivity and specificity. Several methods for labelling leukocytes have been evaluated using P-32 diisopropyl fluorophosphate (DFP-32), H-3 thymidine, Cr-51 chromate, Ga-67 citrate and Tc-99m-sulfur colloid. In-111-oxine has proved so far to be the most reliable agent for labelling leukocytes. In-111-oxine is, however, expensive, not easily available when needed, and its radiation dose to leukocytes is relatively high. Moreover, resolution of the resultant image is relatively poor. Tc-99m is still the agent of choice because of, as compared with the indium, its favorable physical characteristics, lower cost and availability. Now the technique for labelling the leukocytes with technetium is successfully obtained using the lipophilic HAPAO with higher efficiency for granulocytes than for other cells. With this technique it is possible to label leukocytes in plasma to improve the viability of the leukocytes. Inflammation scan using Tc-99m-HMPAO has been evaluated in several laboratories, and difference in methods for separation and labelling accounts for difference in efficiency, viability and biodistribution of the labelled leukocytes. We performed inflammation scan using leukocytes labelled with Tc-99m-HMPAO in three dogs 24 hours after inoculation of live E. Coli and A. Aureus in their right abdominal wall. We separated mixed leukocytes by simple sedimentation using 6% hetastarch (HES) and labelled the leukocytes with Tc-99m-HMPAO in 20% cell free plama diluted with phosphate buffer solution(Fig. 1). Uptake was high in the liver and spleen but is was minimal in the lungs on whole body scan. Kidneys and intestine showed minimal activity although it was high in the urinary bladder(Fig. 2). Uptake of labelled leukocytes in the inflammation site was do(mite on 2 hour-postinjection scan and abscess was clearly delineated on 24 hour-delayed scan with high target-to-nontarget ratio(Fig. 3, 4). Inflammation scan using mixed leukocytes labelled with Tc-99m-HMPAO is very sensitive and specific in early detection of inflammation.

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A Study on Four-year College Curriculum for the Education of Radiological Technology in Korea (방사선학과(放射線學科)의 4년제(年制) 대학(大學) 교육과정(敎育課程)에 대한 연구(硏究))

  • Choi, Jong-Hak;Lee, Sang-Suk;Kim, Young-Il;Kwon, Dal-Gwan;Kim, Heung-Tae;Lim, Han-Young
    • Journal of radiological science and technology
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    • v.18 no.2
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    • pp.87-102
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    • 1995
  • The education of radiologic technology began in the regular institute of higher education in Korea in 1963. Up to now from then, our education to bring up the radiologic technologists has developed greatly in quality and quantity, and now departments of radio-technology are founded in the 16 junior colleges in March, 1995. This study was done to verify the necessity and propriety to reform the education system of radiologic technology which was run as two or three year system of college curriculum for 32 years since 1963, and to search for the method to reform in the future. We got the following results from this research. 1. In the survey, on the desirable education year for radiologic technologists, 63.9 % of professors of department of radio-technology and 63.0 % of radiologic technologists chose the 4 year system, 27.9 % of professors and 34.6 % of radiologic technologists chose the 4 year system added to graduate school. 2. In the survey, on the future development of radiologic equipments and technique, 67.2 % of professors of department of radiologic technology and 86.4 % of radiologic technologists have a view of "revolutional development". Also, on the future tasks or roles of radiologic technologists 95.1% of professors and 94.9% of radiologic technologists have a view that "They will increase". 3. On the necessity of extension of education year to 4 years from 3 years, the factor is that development of medical technique and machinery and tools, advance of qualification of radiologic technologists, enlargement and specialization of the business of the radiologic technologists, ballance of education year with other medical sciences, international competitive power and cooperation of radiologic technology, and education continuation of the graduates of department of radiologic technology. 4. They suggested that in the 4 year curriculum of department of radiologic technology, clinical medicine, quality control of radiation and radiologic equipment, related subjects to the radiologic application and computer application should be enforced and clinical practice should be extended more. 5. On the device to found the 4 year college curriculum of radiologic technology, they suggested that first, 4 year curriculum should be founded through the variety of educational year, secondly, department of radiologic technology should be founded in the 4 year health sciences college, thirdly, educational continuation of the radiologic technologists should be systematized on the basis of life-long education.

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Effect of Coating Technique on the Characteristics of ZnS(Ag) Scintillation Composite for Alpha-ray Detection (알파선 측정용 ZnS(Ag) 섬광 복합체의 특성에 있어 도포방법이 미치는 영향)

  • Jung, Yeon-Hee;Park, So-Jin;Seo, Bum-Kyoung;Lee, Kune Woo;Han, Myeong-Jin
    • Applied Chemistry for Engineering
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    • v.17 no.6
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    • pp.604-608
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    • 2006
  • Polymer composites for measuring the radioactive contamination are prepared by coating ZnS(Ag) powders as a scintillator on polysulfone base layer. The composites consist of the active layer for a scintillation reaction with radioactive wastes and the transparent support layer for transmittance of light photons emitted by scintillation in the active layer. The binding of the active layer, including ZnS(Ag), on the support layer is proceeded via coating with polysulfone as a binder, without any extra adhesive. The coating was obtained by either casting via a Doctor Blade as applicator or screen printing. The prepared composites feature a monolithic structure, resulting in the complete adhesion between two layers. The composite prepared by the casting technique using an applicator holds a good detection efficiency in measuring the alpha radionuclide, but its structure becomes fragile because of warping in morphology. On the contrary, the composite prepared by the screen printing shows a good detection capacity as well as a good stability in a mechanical shape.

Artifact Reduction in Sparse-view Computed Tomography Image using Residual Learning Combined with Wavelet Transformation (Wavelet 변환과 결합한 잔차 학습을 이용한 희박뷰 전산화단층영상의 인공물 감소)

  • Lee, Seungwan
    • Journal of the Korean Society of Radiology
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    • v.16 no.3
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    • pp.295-302
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    • 2022
  • Sparse-view computed tomography (CT) imaging technique is able to reduce radiation dose, ensure the uniformity of image characteristics among projections and suppress noise. However, the reconstructed images obtained by the sparse-view CT imaging technique suffer from severe artifacts, resulting in the distortion of image quality and internal structures. In this study, we proposed a convolutional neural network (CNN) with wavelet transformation and residual learning for reducing artifacts in sparse-view CT image, and the performance of the trained model was quantitatively analyzed. The CNN consisted of wavelet transformation, convolutional and inverse wavelet transformation layers, and input and output images were configured as sparse-view CT images and residual images, respectively. For training the CNN, the loss function was calculated by using mean squared error (MSE), and the Adam function was used as an optimizer. Result images were obtained by subtracting the residual images, which were predicted by the trained model, from sparse-view CT images. The quantitative accuracy of the result images were measured in terms of peak signal-to-noise ratio (PSNR) and structural similarity (SSIM). The results showed that the trained model is able to improve the spatial resolution of the result images as well as reduce artifacts in sparse-view CT images effectively. Also, the trained model increased the PSNR and SSIM by 8.18% and 19.71% in comparison to the imaging model trained without wavelet transformation and residual learning, respectively. Therefore, the imaging model proposed in this study can restore the image quality of sparse-view CT image by reducing artifacts, improving spatial resolution and quantitative accuracy.

A Study on the Awareness of the Irradiated Food (방사선 조사식품에 대한 인식연구)

  • Jung, Bongjae;Park, Byeonggyu;Park, Jikoon;Gang, Sangsik;Noh, Sicheol
    • Journal of the Korean Society of Radiology
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    • v.8 no.6
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    • pp.347-355
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    • 2014
  • Traditionally heating method, pasteurization, irradiation fumigation method and radiation sterilization through a variety of methods to be performed. Irradiation energy requirements compared to the other sterilization methods is small and a strong permeability as a continuous process is possible. Irradiation energy requirements compared to the other sterilization methods is small and a strong permeability as a continuous process is possible. Also sterile, conflict, and control the germination inhibition effective food safety in the food chain has been highlighted as a conservation technique. Foreign countries is carried out extensive research on the safety and the use of irradiation food, gradually increasing. As a result, awareness of the food is irradiated with a low average showed 2.73 point. Therefore through a variety of media to improve the awareness of irradiated food and the active promotion seems to require an appropriate educational program.

Research on Image Quality and Effective dose by Exposure Index Variation (Exposure Index변화에 따른 Image Quality와 Effective dose에 대한 연구: a Monte Carlo Simulation Study)

  • Kim, Hyun Soo;Jeong, Jae Ho;Lee, Jong Woong
    • Journal of the Korean Society of Radiology
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    • v.7 no.1
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    • pp.63-69
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    • 2013
  • Comparing with film-screen system, flat-panel detector has extensive dynamic range. Focusing flat-panel detector, whole body human phantom PBU-50 (Kyoto, kagaku, Japan) was used to perform comparative study of the estimate of image quality and exposure dose. the exposure condition was 81kV and 20mAs, which is used for Abdomen supine exam in clinical area. As a result of the kV change of the interpreted medical image which has over 30dB of PSNR value, the value of DAP shows the difference of 19.6 times. Moreover, the result of comparing kV change with effective dose of ICRP 103 shows that stochastic effect was increased by over exposure. Therefore, it is significantly necessary that digital radiation technical chart will be used to obtain high quality image and make the standard of dose by educating radio-technologist continually.