• Title/Summary/Keyword: Radiation level

Search Result 1,820, Processing Time 0.028 seconds

Risk factors for locoregional recurrence in patients with pathologic T3N0 rectal cancer with negative resection margin treated by surgery alone

  • Baek, Jong Yun;Yu, Jeong Il;Park, Hee Chul;Choi, Doo Ho;Yoo, Gyu Sang;Cho, Won Kyung;Lee, Woo-Yong;Yun, Seong Hyeon;Cho, Yong Beom;Park, Yoon Ah;Kim, Hee Cheol
    • Radiation Oncology Journal
    • /
    • v.37 no.2
    • /
    • pp.110-116
    • /
    • 2019
  • Purpose: This study aimed to identify prognostic factors for locoregional recurrence (LRR) in pT3N0 rectal cancer patients who were treated with surgery alone and had negative resection margin including circumferential resection margin (CRM) for optimal indication of adjuvant radiotherapy. Materials and Methods: We reviewed patients with pT3N0 rectal cancer who were treated via upfront surgery and had no other adjuvant treatment from January 2003 to December 2012. In total, 122 patients who had negative resection margin including negative CRM were included in the analysis. Results: The median follow-up period after surgery was 60 months (range, 3 to 161 months). During this time, 6 patients (4.9%) experienced LRR at the anastomotic site (4 patients), and regional lymphatic area (2 patients). The estimated 5-year rates of overall survival, recurrence-free survival, and LRR-free survival were 96.7%, 84.6%, and 94.0%, respectively. Multivariate analysis showed that level of tumor ≤5 cm was a significant prognostic factor for LRR-free survival (LRRFS) (p = 0.04; hazard ratio = 7.08; 95% confidence interval, 1.06-47.30). Patients with level of tumor ≤5 cm had an estimated 5-year LRRFS of 66.8%, which was much higher than 2.3% in patients with level of tumor >5 cm. There was no significant factor for recurrence-free survival or overall survival. Conclusion: In T3N0 rectal cancer, adjuvant chemoradiotherapy should be recommended in patients with level of tumor ≤5 cm for better local control. However, in patients with pT3N0 disease, negative resection margin, and level of tumor >5 cm, adjuvant chemoradiotherapy should be carefully suggested.

Evaluation of Usefulness of Portal Image Using Electronic Portal Imaging Device (EPID) in the Patients Who Received Pelvic Radiation Therapy (골반강 내 방사선 치료 환자에서 Electronic Portal Imaging Device(EPID)를 이용한 Portal Image의 유용성에 관한 연구)

  • Kim Woo Chul;Park Won;Kim Heon Jong;Park Seong Young;Cho Young Kap;Loh John J;Suh Chang Ok;Kim Gwi Eon
    • Radiation Oncology Journal
    • /
    • v.16 no.4
    • /
    • pp.497-504
    • /
    • 1998
  • Purpose : To evaluate the usefulness of electronic portal imaging device through objective compare of the images acquired using an EPID and a conventional port film Materials and Methods : From Apr. to Oct. 1997, a total of 150 sets of images from 20 patients who received radiation therapy in the pelvis area were evaluated in the Inha University Hospital and Severance Hospital. A dual image recording technique was devised to obtain both electronic portal images and port film images simultaneously with one treatment course. We did not perform double exposure five to ten images were acquired from each patient. All images were acquired from posteroanterior (PA) view except images from two patients. A dose rate of 100-300 Mu/min and a 10-MV X-ray beam were used and 2-10 MUs were required to produce a verification image during treatment. Kodak diagnostic film with metal/film imaging cassette which was located on the top of the EPID detector was used for the port film. The source to detector distance was 140 cm. Eight anatomical landmarks (pelvic brim, sacrum, acetabulum. iliopectineal line, symphysis, ischium, obturator foramen, sacroiliac joint) were assessed. Four radiation oncologist joined to evaluate each image. The individual landmarks in the port film or in the EPID were rated - very clear (1), clear (2), visible (3), not clear (4), not visible (5). Results : Using an video camera based EPID system. there was no difference of image quality between no enhanced EPID images and port film images. However, when we provided some change with window level for the portal image, the visibility of the sacrum and obturator foramen was improved in the portal images than in the port film images. All anatomical landmarks were more visible in the portal images than in the port film when we applied the CLAHE mode enhancement. The images acquired using an matrix ion chamber type EPID were also improved image qualify after window level adjustment. Conclusion : The quality of image acquired using an electronic portal imaging device was comparable to that of the port film. When we used the enhance mode or window level adjustment. the image quality of the EPID was superior to that of the port film. EPID may replace the port film.

  • PDF

The Study of Improvement of the Void Slab Applying the Impedance Method (임피던스법을 이용한 보이드 슬라브의 개선방안에 관한 연구)

  • 오재응;김영식
    • Journal of KSNVE
    • /
    • v.11 no.2
    • /
    • pp.276-284
    • /
    • 2001
  • In apartment buildings, floor-impact sound has been regarded as the major source that causes complaints from residents. It is mainly due to the use of light-weight structures and the lack of researches in terms of floor-impact sound. The purposes of this study are analyzing the characteristics of vibration response and sound radiation of 12type void slabs in the improvements void slab by impedance method and finding the fittest improvements void slab on the 12type void slab. The main results of this study are summarized as below: (1) In the $\frac{1}{3}$ octave band level of sound radiation, $\frac{1}{3}$ octave band levels, measured from four-divided improvement void slab(No.8) and eight-divided improvement void slab(No.12), are 10~25 dB lower than that of standard void slab(No.1) in the 1250 Hz. Especially, eight-divided improvement void slab(No.12) is the best void slab in terms of radiation efficiency of sound level. (2) In the correlation relation of acceleration and sound radiation, standard void slab(No.1), four-divided improvement void slab(No.8), SK standard four-hole void slab(No.10), and eight-divided improvement void slab(No.12) are positive correlation relation.

  • PDF

A Theoretical Consideration about Effects of Radiation on the Physical Properties of PP (PP 재질의 물성에 미치는 방사선의 영향에 대한 이론적 고찰)

  • 김문수;강덕원;엄희문
    • Proceedings of the Korean Radioactive Waste Society Conference
    • /
    • 2003.11a
    • /
    • pp.517-523
    • /
    • 2003
  • The physical properties of polypropylene (PP) membranes under the radiation field were investigated. To calculate radiation flux affecting to PP, it was used MCNP4A Code. The PP membrane and deoxygenation equipment were standardized to bar structure in order to calculate the phonton flux with MCNP4A Code. The change in the properties of the PP membrane to be used in deoxygenation equipment was rarely occurred during the usage work because the radiation level of reactor coolant water was very low level and The doses of radiation workers are very low. From the results, it was found that the Physical properties of PP membranes which used for nuclear power plant reactor coolant water disposal were not rarely changed under the simulated radiation field.

  • PDF

Thermal Properties of Chloroprene Rubber with $^{60}Co\;{\gamma}$-ray Irradiation ($^{60}Co\;{\gamma}$-선 조사에 따른 클로프렌 고무의 열적 특성)

  • Kim, Ki-Yup;Lee, Chung;Ryu, Boo-Hyung
    • Journal of the Korean Society of Safety
    • /
    • v.18 no.4
    • /
    • pp.64-70
    • /
    • 2003
  • The thermal properties of chloroprene rubber (CR) with $^{60}Co\;{\gamma}$-ray irradiation has been investigated. The prepared CR was irradiated up to 1000kGy radiation dose by $^{60}Co\;{\gamma}$-ray and the radiation degradation of CR was investigated by thermogravimetric analysis and differential acanning calorimetry. Dynamic mechanical properties measurement and FT-IR observation are carried out as well. From these analyses results, the glass transition temperature($T_g$), decomposition onset temperature(DOT), oxidative induction time(OIT), the peak temperature of loss modulus and mechanical tan ${\delta}$ values were compared for the radiation degradation level of CR. The tendency between $T_g$ and peak temperature of loss modulus and mechanical tan ${\delta}$ agreed well with radiation doses. Decomposition temperature, OIT and DOT showed the same tendencies as increasing radiation doses. It was verified that these analyses are available to estimate the degradation level of CR.

CLARIFYING THE PARADIGM ON RADIATION EFFECTS & SAFETY MANAGEMENT: UNSCEAR REPORT ON ATTRIBUTION OF EFFECTS AND INFERENCE OF RISKS

  • Gonzalez, Abel J.
    • Nuclear Engineering and Technology
    • /
    • v.46 no.4
    • /
    • pp.467-474
    • /
    • 2014
  • The aim of this paper is to describe a relatively recent international agreement on the widely debated concepts of: (i) attributing effects to low dose radiation exposure situations that have occurred in the past and, (ii) inferring radiation risk to situations that are planned to occur in the future. An important global consensus has been recently achieved on these fundamental issues at the level of the highest international intergovernmental body: the General Assembly of the United Nations. The General Assembly has welcomed with appreciation a scientific report on attributing health effects to radiation exposure and inferring risks that had been prepared the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) following a formal request by the General Assembly.

Proteomic Analysis of Global Changes in Protein Expression During Exposure of Gamma Radiation in Bacillus sp. HKG 112 Isolated from Saline Soil

  • Gupta, Anil Kumar;Pathak, Rajiv;Singh, Bharat;Gautam, Hemlata;Kumar, Ram;Kumar, Raj;Arora, Rajesh;Gautam, Hemant K.
    • Journal of Microbiology and Biotechnology
    • /
    • v.21 no.6
    • /
    • pp.574-581
    • /
    • 2011
  • A Gram-positive bacterium was isolated from the saline soils of Jangpura (U.P.), India, and showed high-level of radiation-resistant property and survived upto 12.5 kGy dose of gamma radiation. The 16S rDNA sequence of this strain was examined, identified as Bacillus sp. strain HKG 112, and was submitted to the NCBI GenBank (Accession No. GQ925432). The mechanism of radiation resistance and gene level expression were examined by proteomic analysis of whole-cell extract. Two proteins, 38 kDa and 86.5 kDa excised from SDS-PAGE, which showed more significant changes after radiation exposure, were identified by MALDI-TOF as being flagellin and S-layer protein, respectively. Twenty selected 2-DE protein spots from the crude extracts of Bacillus sp. HKG 112, excised from 2- DE, were identified by liquid chromatography mass spectrometry (LC-MS) out of which 16 spots showed significant changes after radiation exposure and might be responsible for the radiation resistance property. Our results suggest that the different responses of some genes under radiation for the expression of radiation-dependent proteins could contribute to a physiological advantage and would be a significant initial step towards a fullsystem understanding of the radiation stress protection mechanisms of bacteria in different environments.

Knowledge and attitude change towards radiation protection after radiation safety management education in dental hygiene students (치위생과 학생들의 학업관련 특성에 따른 방사선안전관리 교육 후 방사선 방어에 대한 지식과 태도의 변화)

  • Kim, Sung-Ae;Lee, Ji-Young;Hwang, Se-Hyun;Cho, Mi-Suk;Park, Jung-Hyun;Jung, Nam-Yeong;Yu, Byeng-Chul
    • Journal of Korean society of Dental Hygiene
    • /
    • v.15 no.1
    • /
    • pp.101-109
    • /
    • 2015
  • Objectives: The purpose of the study is to investigate the knowledge and attitude towards radiation protection after radiation safety management education in dental hygiene students. Methods: After receiving informed consents, a self-reported questionnaire was carried out for 135 dental hygiene students in Busan on June 17 for preliminary survey and September 3 for post-education survey, 2011. The questionnaire was modified from Han and consisted of 5 questions of general characteristics, 6 questions of radiation use, 7 questions of scholastic characteristics, 15 questions of knowledge towards radiation safety management, and 15 questions of attitude towards radiation safety management. Cronbach's alpha was 0.808 in the knowledge towards radiation safety management. Attitude towards radiation safety management included 15 questions of general attitude towards radiation safety management, individual and patient, and attitude toward radiation exposure reduction measured by Likert 5 scale. Cronbach's alpha was 0.970 in the attitude towards radiation safety management. Data were analyzed using SAS version 9.2 for educational analysis, technical analysis and multivariate analysis, paired t-test, and GLM. Results: Significant differences were shown in the knowledge and attitudes towards radiation safety management; the level of knowledge was respectively $9.8{\pm}3.0$ and $12.9{\pm}1.9$ points before and after education, and the level of attitude was $4.28{\pm}0.51$ and $4.53{\pm}0.47$ before and after the education. The levels of knowledge and attitude according to general characteristics showed a significant differences in grade and academic results. Post-education survey suggested that the education is very important and necessary and can change the knowledge and attitude towards radiation safety management in the dental hygiene students. Conclusions: Through the radiation safety management education, the levels of knowledge and attitude towards radiation safety management have changed significantly, which showed that the radiation safety management education proved to be very effective. Therefore, an effective radiation safety management education program is necessary to improve the levels of knowledge and attitude towards radiation safety management in the dental hygiene students.

Radiation Exposure Evaluation Depending on Radiation Workers' Locations during Dental Radiography (치과방사선 검사 시 방사선작업종사자의 위치에 따른 방사선 노출 평가)

  • Jeong, Cheonsoo;Kim, Jiyoung
    • Journal of the Korean Society of Radiology
    • /
    • v.9 no.7
    • /
    • pp.433-438
    • /
    • 2015
  • To evaluate the radiation exposure level based on radiation workers' locations in dental radiography, the radiation dose rate in the radiographic room, lead glass, and operation system was measured. To that end, various devices were used, such as a Standard(Max-GLS, Shinhung), a panorama (PCH-2500, Vatech), a cephalometric radiography (PCH-2500), and a cone beam CT (PHT-30LFO, Vatech), as well as a PM1405 equipment as a radiation meter. Radiography conditions were set the same as the factors used in the clinical setting. As the result, the cone beam CT turned out the highest with 98 uSv and the standard showed the lowest level with 0.4 uSv/h. The panorama was measured to be higher than the Cephalo due to its different focus mode. On the lead glass surface and in the operation stand, the oral radiography device, panoramic, and Cephalo all were measured below the recording level. However, the cone beam CT was measured to have the leakage dose. Thus, radiation involved workers should be equipped with appropriate protection tools and reduce radiography time as much as possible. In addition, the structure of the radiation chamber should be also designed efficiently. Dental radiography has continued to grow in recent years, so it is necessary take appropriate protection measures for patients and radiation workers.

A Color Difference of White Polyurethane Coating Containing Antioxidant (산화방지제가 첨가된 백색 폴리우레탄 도막의 색차)

  • Lee, Phil-Woo;Yun, Young-Ki
    • Journal of the Korean Wood Science and Technology
    • /
    • v.22 no.3
    • /
    • pp.45-50
    • /
    • 1994
  • This experiment was to investigate the effects of UV radiation and chemical treatments on the color difference in antioxidant (Tris(2,4-di-t-butyl phenoxy) phosphite)-containing polyurethane coats. The results obtained were summerized as follows: 1. The color difference increased as the exposure time of UV radiation increases, but decreased as addition level of antioxidant increaes. 2. After 400 hours exposure to UV radiation, the color difference respectively showed 6.13 and 5.94 at 0.7 % and 1.0 % addition level but appeared more severe below 0.7 % addition level. Thus, antioxidant prevented discoloration effectively. 3. The color difference of films by chemical treatments increased after 8 hours. Color difference of films treated with 5 % acetic acid($CH_3COOH$), 30 % ethyl alchol ($CH_3CH_2OH$) showed 7.31 and 7.30 respectively. 1 % sodium hydroxide treatment showed 1.86 color difference after 8 hours.

  • PDF