• Title/Summary/Keyword: Radiation level

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Endonuclease G is Upregulated and Required in Testicular Germ Cell Apoptosis after Exposure to 60 Hz at 200 μT

  • Park, Sungman;Kim, Min-Woo;Kim, Ji-Hoon;Lee, Yena;Kim, Min Soo;Lee, Yong-Jun;Kim, Young-Jin;Kim, Hee-Sung;Kim, Yoon-Won
    • Journal of electromagnetic engineering and science
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    • v.15 no.3
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    • pp.142-150
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    • 2015
  • Several reports supported that continuous exposure to 60 Hz magnetic field (MF) induces testicular germ cell apoptosis in vivo. We recently evaluated duration- and dose-dependent effects of continuous exposure to a 60 Hz MF on the testes in mice. BALB/c male mice were exposed to a 60 Hz MF at $100{\mu}T$ for 24 hours a day for 2, 4, 6, or 8 weeks, and at 2, 20 or $200{\mu}T$ for 24 hours a day for 8 weeks. To induce the apoptosis of testicular germ cell in mice, the minimum dose is $20{\mu}T$ at continuous exposure to a 60 Hz MF for 8 weeks, and the minimum duration is 6 weeks at continuous exposure of $100{\mu}T$. Continuous exposure to a 60 Hz MF might affect duration- and dose-dependent biological processes including apoptotic cell death and spermatogenesis in the male reproductive system of mice. The safety guideline of the International Commission on Non-Ionizing Radiation Protection (ICNIRP) indicates that the permissible maximum magnetic flux density for general public exposure is $200{\mu}T$ at 60 Hz EMF (ICNIRP Guidelines, 2010). In the present study, we aimed to examine the expression of pro- and anti-apoptotic genes regulated by the continuous exposure to 60 Hz at $200{\mu}T$ in Sprague-Dawley rats for 20 weeks. The continuous exposure to 60 Hz at $200{\mu}T$ does not affect the body and testicular weight in rats. However, exposure to 60 Hz MF significantly affects testicular germ cell apoptosis and sperm count. Further, the apoptosis-related gene was scrutinized after exposure to 60 Hz at $200{\mu}T$ for 20 weeks. We found that the message level of endonuclease G (EndoG) was greatly increased following the exposure to 60 Hz at $200{\mu}T$ compared with sham control. These data suggested that 60 Hz magnetic field induced testicular germ cell apoptosis through mitochondrial protein Endo G.

A Study of Limitation of Service Area by UWB Transmission Jamming in Broadcasting Communication System (방송통신 시스템에서 UWB 전파가 서비스에 미치는 영향에 관한 연구)

  • Park, No-Jin
    • Journal of The Institute of Information and Telecommunication Facilities Engineering
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    • v.7 no.1
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    • pp.23-31
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    • 2007
  • In this paper, UWB system did research about effect that interference effect with neighborhood single equipment or group equipment gets in broadcasting communication service. For this, 2.6425GHz SDMB(Satellite Digital Multimedia Broadcasting) that a special of electric wave interference is near frequency-band including interference of signal by unnecessary radiation level that is radiated in UWB system, and degree of 3.4125GHz broadcasting relay net that is In-band frequency-band and interference effect that get in service analyzed comparison and, modulation of broadcasting relay net and interference measurement equipment used Impulse and OFDM methods. Impulse method was $BER\;=\;1{\times}\;10^{-4}$ that broadcasting signal receiption is possible at 1.4m point because interference effect happens from 2m point in SDMB system, and it was $BER\;=\;1{\times}\;10^{-4}$ that OFDM method receives interference effect from 0.8m point and broadcasting signal receiption is possible at 0.5m point. Also, about Gap-Filler center frequency, In case of space interval more than 0.01m, there was no interference effect. Therefore, for the electric wave of UWB system that is small output applies to system without interference effect in broadcasting communication service, confirmed that UWB system of OFDM method is less interference effect than UWB system of Impulse method.

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Effect of Irradiation on Apoptosis, Cell Cycle Arrest and Calcified Nodule Formation of Rat Calvarial Osteoblast (방사선 조사가 배양된 조골세포의 apoptosis와 세포주기의 변화 및 석회화 결절 형성에 미치는 영향에 관한 연구)

  • Lee Young-Mi;Choi Hang-Moon;Heo Min-Suk;Lee Sam-Sun;Choi Soon-Chul;Park Tae-Won
    • Imaging Science in Dentistry
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    • v.30 no.3
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    • pp.189-198
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    • 2000
  • Purpose: The study was aimed to detect the induction of apoptosis, cell cycle arrest and calcified nodule formation after irradiation on primarily cultured osteoblasts. Materials and Methods: Using rat calvarial osteoblasts, the effects of irradiation on apoptosis, cell cycle arrest, and calcified nodule formation were studied. The single irradiation of 10 and 20 Gy was done with 5.38 Gy/min dose rate using the l37Cs cell irradiator at 4th and 14th day of culture. Apoptosis induction and cell cycle arrest were assayed by the flowcytometry at 1, 2, 3, and 4 days after irradiation. The formation of calcified nodules was observed by alizarin red staining at 1, 3, 10, 14 days after irradiation at 4th day of culture, and at 1, 4, 5 days after irradiation at 14th day of culture. Results: Apoptosis was not induced by 10 or 20 Gy independent of irradiation and culture period. Irradiation did not induced G1 arrest in post-irradiated ostedblasts. After irradiation at 4th-day of culture, G2 arrest was induced but it was not statistically significant after irradiation at 14th-day of culture. In the case of irradiated cells at 4th day of culture, calcified nodules were not formed and at 14th-day of culture after irradiation, calcified nodule formation did not affected. Conclusion: Taken together, these results suggest that irradiation at the dose of 10-20 Gy would not affect apoptosis induction of osteoblasts. Cell cycle and calcified nodule formation were influenced by the level of differentiation of osteblasts.

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Search of Characteristic for Dose Distribution Presented by Multi­isocentric Stereotactic Radiosurgical Plan Using Linear Accelerator (선형 가속기를 이용한 정위적 방사선 수술시 병소내 선량분포의 특성조사)

  • 최경식;오승종;이형구;최보영;전흥재;서태석
    • Progress in Medical Physics
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    • v.14 no.4
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    • pp.225-233
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    • 2003
  • The goal of a radiation treatment plan is to deliver a homogeneous dose to a target with minimal irradiation of the adjacent normal tissues. Dose uniformity is especially important for stereotactic radiosurgery using a linear accelerator. The dose uniformity and high dose delivery of a single spherical dose distribution exceed 70%. This also results with a similar stereotactic radiosurgical plan using a Gamma Knife. The dose distribution produced in a stereotactic radiosurgical plan using a Gamma Knife and Linear accelerator is spherical, and the application of the sphere packing arrangement in a real radiosurgical plan requires much time and skill. In this study, we found a characteristic of dose distribution with transformation of beam parameters that must be considered in a radiosurgical plan for effective radiosurgery. First, we assumed a cylinder type tumor model and a cube type tumor model. Secondly, the results of the tumor models were compared and analyzed with dose profiles and DVH_(Dose Volume Histogram) representative dose distribution. We found the optimal composition of beam parameters_(i.e. collimator size, number of isocenter, gap of isocenters etc.), which allowed the tumor models to be involved in the isodose curve at a high level. In conclusion, the characteristics found in this study are helpful for improving the effectiveness and speed of a radiosurgical plan for stereotactic radiosurgery.

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Analysis of Radiology Students' Behavior in Wearing Radiation Protection Equipment - based on the Theory of Planned Behavior (계획된 행위이론을 적용한 방사선학과 대학생들의 방사선 방어용 보호장구 착용에 대한 분석)

  • Noh, Ji-Sook;Lee, Byung-Hoon;Bea, Sang-Yul;Park, Hyung-Su;Ryu, So-Yen;Park, Jong
    • The Journal of the Korea Contents Association
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    • v.11 no.9
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    • pp.443-452
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    • 2011
  • This research aims at investigating the factors that affects the wearing of the nuclear protection equipment by radiology students. We measured the factors related to the wearing of the nuclear protection equipment based on the theory of planned behavior (TPB). We collected 192 survey records from 230 radiology students in Kwang-ju and Chun-nam providence who finished the clinical training. Based on Logistic Regression analysis, we found that the wearing of the nuclear protection equipment is statistically more probable as the level of study is lower, the scale of practicing hospital is smaller, the attitude rating is lower, and the rating of perceived behavioral control is higher. We argue that the development of educational program considering factors like the perceived behavioral control is required to enhance the degree of wearing the nuclear protection equipment in the clinical training of college students.

Changes in Growths of Tomato and Grafted Watermelon Seedlings and Allometric Relationship among Growth Parameters as Affected by Shading During Summer (여름철 차광처리에 따른 토마토묘와 수박 접목묘의 생육과 생육지표간 상대적 관계)

  • Kang, Yun-Im;Kwon, Joon-Kook;Park, Kyoung-Sub;Yu, In-Ho;Lee, Si-Young;Cho, Myeong-Whan;Kang, Nam-Jun
    • Journal of Bio-Environment Control
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    • v.19 no.4
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    • pp.275-283
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    • 2010
  • This study was conducted to examine the changes in growths of tomato and watermelon seedlings and the relationship among growth parameters which are used to evaluate healthy seedling as affected by shading. Plants were grown under 0%, 25%, 50%, and 75% shadings using polyethylene films. Leaf area index (LAI) of tomato and grafted watermelon seedlings increased under 50% and 75% shading. Total dry weight decreased with increase of shading level. The growth rates of stem diameter, LAI, total weight were faster under 50% and 75% shading with increase of integral radiation than under 0% and 25% shading. Stem diameters of tomato and grafted watermelon seedlings showed no significant differences among shading regimes. Stem diameters of tomato seedlings had upward tendency with increase of total dry weight and shoot height, but there were no significant differences among shading regimes. Stem diameters of grafted watermelon seedlings had no relationship with shoot height. These results indicate that stem diameter of tomato seedlings is not appropriate for assessing seedlings quality but stem diameter of grafted watermelon seedlings with shoot height is available.

Analysis of Exposure Dose According to Chest and Abdomen Combine CT Exam Method (CT 흉·복부 통합검사 시 선량분석)

  • Mo, KyeongHwan;Han, DongKyoon;Lim, HyunSoo;Jeon, WooJin
    • Journal of the Korean Society of Radiology
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    • v.8 no.7
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    • pp.401-408
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    • 2014
  • The purpose of this study is confirmed to usefulness between division exam and combine exam of chest and abdomen according to comparing chest and abdomen radiation dose of division exam and combine exam in CT exam method. This study was conducted on patients who were admitted to the E hospital from July 2013 to March 2014 underwent CT studies for the diagnosis of chest and abdomen disease. In study result, male dose were more higher than female dose according to gender analysis of exposure dose that combine exam effective dose were male $33.10{\pm}2.75mSv$, female $31.66{\pm}3.12mSv$ and chest exam effective dose were male $9.07{\pm}2.62mSv$, female $8.30{\pm}2.18mSv$(p<0.05). And, division exam dose and combine exam dose were similar in gender comparison (p>0.05). And, combine exam effective dose, only chest exam effective dose, only abdomen exam effective dose were more higher than DRL(Diagnostic Reference Level) in comparison of patient exposure dose with DRL (p<0.05). In conclusion, chest-abdomen combine exam dose and division exam dose were similar. The chest-abdomen combine study can be used as follow-up and emergency trauma patients. That study will be reduce exam time and the occurrence risk of side effect of the contrast medium.

The Characteristics for BNCT facility in Hanaro Reactor

  • Soheigh Suh;Lee, Dong-Han;Ji, Young-Hoon;Lee, Dong-Hoon;Yoo, Seong-Yul;Rhee, Chang-Hun;Rhee, Soo-Yong;Jun, Byung-Jin
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.161-163
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    • 2002
  • The BNCT(Boron Neutron Capture Therapy) facility has been developed in Hanaro(High-flux Advanced Neutron Application Reactor), a research reactor of Korea Atomic Energy Research Institute. A typical tangenial beam port is utilized with this BNCT facility. Thermal neutrons can be penetrated within the limits of the possible maximum instead of being filtered fast neutrons and gamma rays as much as possible using the silicon and bismuth single crystals. In addition to, the liquid nitrogen (LN$_2$) is used to cool down the silicon and bismuth single crystals for the increase of the penetrated thermal neutron flux. Neutron beams for BNCT are shielded using the water shutter. The water shutter was designed and manufactured not to interfere with any other subsystem of Hanaro when the BNCT facility is operated. Also, it is replaced with conventional beam port plug in order to cut off helium gas leakage in the beam port. A circular collimator, composed of $\^$6/Li$_2$CO$_3$ and polyethylene compounds, is installed at the irradiation position. The measured neutron flux with 24 MW reactor power using the Au-198 activation analysis method is 8.3${\times}$10$\^$8/ n/cm$^2$ s at the collimator, exit point of neutron beams. Flatness of neutron beams is proven to ${\pm}$ 6.8% at 97 mm collimator. According to the result of acceptance tests of the water shutter, the filling time of water is about 190 seconds and drainage time of it is about 270 seconds. The radiation leakages in the irradiation room are analyzed to near the background level for neutron and 12 mSv/hr in the maximum for gamma by using BF$_3$ proportional counter and GM counter respectively. Therefore, it is verified that the neutron beams from BNCT facility in Hanaro will be enough to utilize for the purpose of clinical and pre-clinical experiment.

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Development of a Solar Powered Water Pump by Using Low Temperature Phase Change Material ­ System Construction and Operation Analysis ­ (저온 상변화 물질 특성을 이용한 태양열 물펌프 실용화 연구개발(II) ­시스템 구성 및 작동분석)

  • 김영복;이양근;이승규;김성태;나우정;민영봉
    • Journal of Animal Environmental Science
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    • v.9 no.2
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    • pp.69-78
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    • 2003
  • In this study, the energy conversion equipment from the radiation energy to mechanical energy by using n­pentane as the operating fluid was constructed and the performance to pump the water was tested for the utilization of solar powered water pump. The equipment was designed optimally, after the theoretical analyses of the water pumping head and water quantity per cycle were done. The pentane vapour temperature in the condenser and the temperature of the outlet water from the condenser became lowered and the heat transfer rate became higher with decreasing the water inlet level to the condenser. The temperature difference between the condenser and the water tank was significant. Therefore, the distance between the water tank and condenser was recommended to be shorten and the diameter of their connecting pipe was recommended to be narrow in order to reduce the resistance of the fluid passage and improve the heat transfer rate. The amount of water pumped was 1.6­2.4 liters. Mass flow rate of the cooling water became lowered when the cooling water pipe was prolonged from the condenser to improve the heat transfer rate.

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Development of Automatic Remote Exposure Controller for Gamma Radiography (감마선투과검사 장치의 자동 원격조작기 개발)

  • Joo, Gwang-Tae;Shin, Jin-Seong;Kim, Dong-Eun;Song, Jung-Ho;Choo, Seung-Hwan;Chang, Hong-Keun
    • Journal of the Korean Society for Nondestructive Testing
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    • v.22 no.5
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    • pp.490-499
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    • 2002
  • Recently, gamma radiographic equipments have been used about 1,000 sets manually and operated by about 2,500 persons in Korea. In order for a radiography to work effectively with avoiding any hazard of the high level radiation from the source, many field workers have expected developing a wireless automatic remote exposure controller. The KlTCO research team has developed an automatic remote exposure controller that can regulate the speed of $0.4{\sim}1.2m/s$ by BLDC motor of 24V 200W which has output of $54kgf{\cdot}cm$, suitable torque and safety factor for the work. And the developed automatic remote exposure controller can control rpm of motor, pigtail position by photo-sensor and exposure time by timer to RF sensor. Thus, the developed equipment is expected that the unit can be used in many practical applications with benefits in economical advantage to combine the use of both automatic and manual type because attachment is possible existent manual remote exposure controller, AC and DC combined use.