• 제목/요약/키워드: Radiation intensity

검색결과 978건 처리시간 0.03초

Dosimetric Evaluation of Low-Dose Spillage Volumes for Head and Neck Cancer Using Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy Treatment Techniques

  • Kumar, Gourav;Bhushan, Manindra;Kumar, Lalit;Kishore, Vimal;Raman, Kothanda;Kumar, Pawan;Barik, Soumitra;Purohit, Sandeep
    • 한국의학물리학회지:의학물리
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    • 제32권3호
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    • pp.70-81
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    • 2021
  • Purpose: This study was designed to investigate the dosimetric difference between intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) in head and neck cancer (HNC). The study primarily focuses on low-dose spillage evaluation between these two techniques. Methods: This retrospective study involved 45 patients with HNC. The treatment plans were generated using the IMRT and VMAT techniques for all patients. Dosimetric comparisons were performed in terms of target coverage, organ-at-risk (OAR) sparing, and various parameters, including conformity index, uniformity index, homogeneity index, conformation number, low-dose volumes, and normal tissue integral dose (NTID). Results: No significant (P>0.05) difference in planning target volume coverage (D95%) was observed between IMRT and VMAT plans for supraglottic larynx, hard palate, and tongue cancers. A decrease in dose volumes ranging from 1 Gy to 30 Gy was observed for VMAT plans compared with those for IMRT plans, except for V1Gy and V30Gy for supraglottic larynx cancer and V1Gy for tongue cancer. Moreover, decreases (P<0.05) in NTID were observed for VMAT plans compared with that for IMRT plans in supraglottic larynx (4.50%), hard palate (12.80%), and tongue (7.76%) cancers. In contrast, a slight increase in monitor units for VMAT compared with those for IMRT in supraglottic larynx (0.46%), hard palate (2.54%), and tongue (7.56%) cancers. Conclusions: For advanced-stage HNC, both IMRT and VMAT offer satisfactory clinical plans. VMAT offers a conformal and homogeneous dose distribution with comparable OAR sparing and higher dose falloff outside the target volume than IMRT, which provides an edge to reduce the risk of secondary malignancies for HNC over IMRT.

Mushroom 형태의 EBG 구조가 집적된 마이크로스트립 패치 안테나의 방사 특성 해석 (Analysis of Radiation Characteristics of Microstrip Patch Antennas Integrated with Mushroom-like EBG Structures)

  • 김상우;김부균;신종덕
    • 대한전자공학회논문지TC
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    • 제45권4호
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    • pp.43-52
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    • 2008
  • 패치 안테나 주위에 mushroom 형태를 가지는 EBG 구조를 길이 방향, 폭 방향과 모든 방향으로 집적한 경우 구조 파라미터에 따른 패치 안테나의 방사 특성을 연구하였다. EBG 구조가 길이 방향을 따라 집적된 경우가 가장 방사 특성이 좋음을 볼 수 있었다. EBG 패치 edge에서 패치 안테나의 피드까지의 거리가 같은 경우가 패치 안테나의 중심까지의 거리가 같은 경우와 비교하여 E-평면 방사패턴이 대칭적이고 전방방사 크기가 커지고 후방방사 크기가 작아짐을 볼 수 있었다. 사용하는 EBG 구조의 주기 수가 4주기 이상이 되게 되면 방사특성 변화는 거의 발생하지 않음을 볼 수 있었다.

Dosimetric comparison of axilla and groin radiotherapy techniques for high-risk and locally advanced skin cancer

  • Mattes, Malcolm D.;Zhou, Ying;Berry, Sean L.;Barker, Christopher A.
    • Radiation Oncology Journal
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    • 제34권2호
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    • pp.145-155
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    • 2016
  • Purpose: Radiation therapy targeting axilla and groin lymph nodes improves regional disease control in locally advanced and high-risk skin cancers. However, trials generally used conventional two-dimensional radiotherapy (2D-RT), contributing towards relatively high rates of side effects from treatment. The goal of this study is to determine if three-dimensional conformal radiation therapy (3D-CRT), intensity-modulated radiation therapy (IMRT), or volumetric-modulated arc therapy (VMAT) may improve radiation delivery to the target while avoiding organs at risk in the clinical context of skin cancer regional nodal irradiation. Materials and Methods: Twenty patients with locally advanced/high-risk skin cancers underwent computed tomography simulation. The relevant axilla or groin planning target volumes and organs at risk were delineated using standard definitions. Paired t-tests were used to compare the mean values of several dose-volumetric parameters for each of the 4 techniques. Results: In the axilla, the largest improvement for 3D-CRT compared to 2D-RT was for homogeneity index (13.9 vs. 54.3), at the expense of higher lung $V_{20}$ (28.0% vs. 12.6%). In the groin, the largest improvements for 3D-CRT compared to 2D-RT were for anorectum $D_{max}$ (13.6 vs. 38.9 Gy), bowel $D_{200cc}$ (7.3 vs. 23.1 Gy), femur $D_{50}$ (34.6 vs. 57.2 Gy), and genitalia $D_{max}$ (37.6 vs. 51.1 Gy). IMRT had further improvements compared to 3D-CRT for humerus $D_{mean}$ (16.9 vs. 22.4 Gy), brachial plexus $D_5$ (57.4 vs. 61.3 Gy), bladder $D_5$ (26.8 vs. 36.5 Gy), and femur $D_{50}$ (18.7 vs. 34.6 Gy). Fewer differences were observed between IMRT and VMAT. Conclusion: Compared to 2D-RT and 3D-CRT, IMRT and VMAT had dosimetric advantages in the treatment of nodal regions of skin cancer patients.

Dosimetric comparison of coplanar and non-coplanar volumetric-modulated arc therapy in head and neck cancer treated with radiotherapy

  • Gayen, Sanjib;Kombathula, Sri Harsha;Manna, Sumanta;Varshney, Sonal;Pareek, Puneet
    • Radiation Oncology Journal
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    • 제38권2호
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    • pp.138-147
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    • 2020
  • Purpose: To evaluate the dosimetric variations in patients of head and neck cancer treated with definitive or adjuvant radiotherapy using optimized non-coplanar (ncVMAT) beams with coplanar (cVMAT) beams using volumetric arc therapy. Materials and Methods: Twenty-two patients of head and neck cancer that had received radiotherapy using VMAT in our department were retrospectively analyzed. Each of the patients was planned using coplanar and non-coplanar orientations using an optimized couch angle and fluences. We analyzed the Conformity Index (CIRTOG), Dose Homogeneity Index (DHI), Heterogeneity Index (HIRTOG), low dose volume, target and organs-at-risk coverage in both the plans without changing planning optimization parameters. Results: The prescription dose ranged from 60 Gy to 70 Gy. Using ncVMAT, CIRTOG, DHI and HIRTOG, and tumor coverage (ID95%) had improved, low dose spillage volume in the body V5Gy was increased and V10Gy was reduced. Integral dose and intensity-modulated radiation therapy factor had increased in ncVMAT. In the case of non-coplanar beam arrangements, maximum dose (Dmax) of right and left humeral head were reduced significantly whereas apex of the right and left lung mean dose were increased. Conclusion: The use of ncVMAT produced better target coverage and sparing of the shoulder and soft tissue of the neck as well as the critical organ compared with the cVMAT in patients of head and neck malignancy.

상반성 기법과 p-p method를 이용한 구조물 방사소음 유한요소해석 기법 연구 (Study on sound radiation estimation using a reciprocity technique and p-p method by finite element simulation)

  • 유지우;박헌;이지운
    • 한국음향학회지
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    • 제42권1호
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    • pp.1-6
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    • 2023
  • 구조진동 소음 문제의 평가에 있어 방사소음은 중요한 물리적 특성으로 음향 인텐시티 측정으로 확인이 가능하지만, 시간이 오래 걸리고 까다로운 측정 조건 때문에 시험을 꺼리는 경향이 많다. 그 대안으로 시뮬레이션이 사용되고 있으며, 그 정확도도 높다. 문제는 방사소음 파워와 방사효율 같은 중요한 물리량을 얻기 위해서는 이를 계산해 주는 특정한 소프트웨어가 필요하다는 점이다. 본 연구에서는 이런 관점에서 일반적인 유한요소 해석 소프트웨어를 사용하여 방사소음 파워와 방사 효율을 계산하는 후처리 기법을 제안한다. 제안된 두가지 방법은 기본적으로 시험에서 사용하는 방법을 시뮬레이션에 활용하는 것이다. 첫번째 방법은 상반성 기법을 이용하는 것이며, 두번째 방법은 인접한 2개의 위치에서 계산된 음압을 이용하는 방법이다. 두가지 방법이 모두 효과적으로 방사소음 파워를 예측할 수 있음을 보였으며, 그 한계도 설명하였다.

초음파의 세기를 구하기 위한 수치 해석적 방법 (Numerical Analysis of Ultrasonic Radiation Intensities (In Liquid))

  • 이상희
    • 산업기술연구
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    • 제8권
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    • pp.65-70
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    • 1988
  • The intensity of ultrasound in liquid is calculated by improved analytic method. Helmholtz equation or Rayleigh's proposition does not offer the analytic solution. Considering a bounded medium, the use of the image source method in electromagnetic thoery gives a new way of calculating the total ultrasonic intensity in liquid. Some methods of measuring the intensities are also mentioned.

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임의의 위치에 가상 인텐시티 형성 방법: 방법론과 그 물리적 의미 (A method to generate virtual intensity at arbitrary position: Methodology and its physical meanings)

  • 최정우;김양한
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2003년도 춘계학술대회논문집
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    • pp.652-657
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    • 2003
  • This paper proposes a method to generate virtual intensity field in space. The sound field of a zone enclosing the listener position is controlled to have maximum acoustic intensity to the desired direction. In order to control acoustic intensity of a zone, space-averaged active intensity is introduced. The ratio of space-averaged active intensity and control effort is defined as a cost function and expressed as a function of source control signals. It is shown that the cost function represents radiation efficiency of multiple sources. The control signals maximizing the cost function is found through eigenvalue analysis. The proposed method is verified by numerical simulations performed in free field condition, and the results provide a relation between wavelength and the size of controllable intensity field.

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Gamma Evaluation with Portal Dosimetry for Volumetric Modulated Arc Therapy and Intensity-Modulated Radiation Therapy

  • Kim, Jung-in;Choi, Chang Heon;Park, So-Yeon;An, HyunJoon;Wu, Hong-Gyun;Park, Jong Min
    • 한국의학물리학회지:의학물리
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    • 제28권2호
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    • pp.61-66
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    • 2017
  • The aim of this study is to investigate the characteristics of portal dosimetry in comparison with the MapCHECK2 measurments. In this study, a total of 65 treatment plans including both volumetric modulated arc therapy (VMAT) and intensity-modulated radiation therapy (IMRT) were retrospectively selected and analyzed (45 VMAT plans and 20 IMRT plans). A total of 4 types of linac models (VitalBeam, Trilogy, Clinac 21EXS, and Clianc iX) were used for the comparison between portal dosimetry and the MapCHECK2 measurements. The VMAT plans were delivered with two VitalBeam linacs (VitalBeam1 and VitalBeam2) and one Trilogy while the IMRT plans were delivered with one Clinac 21EXS and one Clinacl iX. The global gamma passing rates of portal dosimetry and the MapCHECK2 measurements were analyzed with a gamma criterion of 3%/3 mm for IMRT while those were analyzed with a gamma criterion of 2%/2 mm for VMAT. Spearman's correlation coefficients (r) were calculated between the gamma passing rates of portal dosimetry and those of the MapCHECK2 measurements. For VMAT, the gamma passing rates of portal dosimetry with the VitalBeam1, VitalBeam2, and Trilogy were $97.3%{\pm}3.5%$, $97.1%{\pm}3.4%$, and $97.5%{\pm}1.9%$, respectively. Those of the MapCHECK2 measurements were $96.8%{\pm}2.5%$, $96.3%{\pm}2.7%$, and $97.4%{\pm}1.3%$, respectively. For IMRT, the gamma passing rates of portal dosimetry with Clinac 21EXS and Clinac iX were $99.7%{\pm}0.3%$ and $99.8%{\pm}0.2%$, respectively. Those of the MapCHECK2 measurements were $96.5%{\pm}3.3%$ and $97.7%{\pm}3.2%$, respectively. Except for the result with the Trilogy, no correlations were observed between the gamma passing rates of portal dosimetry and those of the MapCHECK2 measurements. Therefore, both the MapCHECK2 measurements and portal dosimetry can be used as an alternative to each other for patient-specific QA for both IMRT and VMAT.

Dosimetric advantages and clinical outcomes of simultaneous integrated boost intensity-modulated radiotherapy for anal squamous cell carcinoma

  • Sakanaka, Katsuyuki;Itasaka, Satoshi;Ishida, Yuichi;Fujii, Kota;Horimatsu, Takahiro;Mizowaki, Takashi;Sakai, Yoshiharu;Hiraoka, Masahiro
    • Radiation Oncology Journal
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    • 제35권4호
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    • pp.368-379
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    • 2017
  • Purpose: The purpose of this study was to explore the dosimetric difference between simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) and three-dimensional conformal radiotherapy (3DCRT), and the clinical outcomes of anal squamous cell carcinoma (ASCC) chemoradiotherapy featuring SIB-IMRT. Materials and Methods: This study included ten patients with ASCC who underwent chemoradiotherapy using SIB-IMRT with 5-fluorouracil and mitomycin C. SIB-IMRT delivered 54 Gy to each primary tumor plus metastatic lymph nodes and 45 Gy to regional lymph nodes, in 30 fractions. Four patients received additional boosts to the primary tumors and metastatic lymph nodes; the median total dose was 54 Gy (range, 54 to 60 Gy). We additionally created 3DCRT plans following the Radiation Therapy Oncology Group 9811 protocol to allow dosimetric comparisons with SIB-IMRT. Locoregional control, overall survival, and toxicity were calculated for the clinical outcome evaluation. Results: Compared to 3DCRT, SIB-IMRT significantly reduced doses to the external genitalia, bladder, and intestine, delivering the doses to target and elective nodal region. At a median follow-up time of 46 months, 3-year locoregional control and overall survival rates were 88.9% and 100%, respectively. Acute toxicities were treated conservatively. All patients completed radiotherapy with brief interruptions (range, 0 to 2 days). No patient experienced ${\geq}grade$ 3 late toxicity during the follow-up period. Conclusion: The dosimetric advantages of SIB-IMRT appeared to reduce the toxicity of chemoradiotherapy for ASCC achieving high locoregional control in the extended period.