• Title/Summary/Keyword: Radiation hazard

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Studies on the internal decontamination of radioiodine (Radioiodine의 체내오염(體內汚染)에 대(對)한 긴급처치연구(緊急處置硏究))

  • Chung, In-yong;Kim, Tae-hwan;Chung, Hyun-woo;Chin, Soo-yil;Yun, Taik-koo
    • Korean Journal of Veterinary Research
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    • v.28 no.2
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    • pp.391-396
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    • 1988
  • Appreciable radiation exposures certainly occur in the workers who handle radioiodine in biochemical research, nuclear medicine diagnostics with the development of nuclear industries. But in the case of occurring the nuclear accidents, the early medical treatment of radiation injury should be necessary but little was reported in korea till now. Accordingly, to achieve of the basic data for protective roles and medical treatment of radiation injury, the present studies were carried out to evaluate the decontamination of radioiodine by the administration of the antithyroid drugs. The results observed are summarized as follows: 1. The administration of sodium iodide and potassium iodide results in rapid excretion of radioiodine and reduction of the whole body retention than the saline-only group. 2. Reguarding to thyroid protective effects, sodium iodide, potassium iodide and saline were effected significant in order. 3. In the control(saline) group, if administered with enough fluids, the whole body retention of radioiodine is reduced temporary shifts. But as far as radioprotective effects is concerned, saline was not more in the protective effects than the other groups. In conclusion, in case of nuclear accidents, if being administered sodium iodide and saline as quickly as possible, the radioprotective effects against the radiation hazard might be markedly increased in the internal contamination of radioiodine.

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Implementation of Radiation Damage in Vitro Model using Swine Skin (돼지피부를 사용한 방사선 체외 장해모델 구현연구)

  • Jung, Hongmoon;Won, Doyeon;Jeong, Dong Kyung;Jung, Jaeeun
    • Journal of the Korean Society of Radiology
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    • v.10 no.2
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    • pp.139-144
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    • 2016
  • The study of radiation-hazard in the human skin tissue is carried out by direct irradiating to experimental animals. The influences of a radiation to the animal's skin tissue are analyzed from this experiment. However, this also accompanies losses in terms of both time and economy. In this study, we simulated human tissue by using a swine skin tissue. The depth of the swine skin tissue for the experiment is determined, and the amount of the direct radiation below this skin depth is analyzed numerically. The amount of the radiation occurred by exposure below the skin tissue can be inferred. Moreover, it is possible to use only cells effectively and animal experiments to analyze the body-hazard by radiation.

Treatment outcome and risk analysis for cataract after radiotherapy of localized ocular adnexal mucosa-associated lymphoid tissue (MALT) lymphoma

  • Park, Hee Hyun;Lee, Sea-Won;Sung, Soo Yoon;Choi, Byung Ock
    • Radiation Oncology Journal
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    • v.35 no.3
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    • pp.249-256
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    • 2017
  • Purpose: We retrospectively reviewed the results of radiotherapy for localized ocular adnexal MALT lymphoma (OAML) to investigate the risk factors of cataract. Methods: Sixty-seven patients with stage IE OAML treated with radiotherapy at Seoul St. Mary's Hospital from 2001 to 2016 were included. Median treatment dose was 30 Gy. Lens protection was done in 52 (76%) patients. Radiation therapy (RT) extent was as follows: superficial (82.1%), tumor mass (4.5%), and entire orbital socket (13.4%). The risk factors for symptomatic cataract were analyzed using the Cox proportional hazard model. Results: Median follow-up time was 50.9 months (range, 1.9 to 149.4 months). All patients were alive at the time of analysis. There were 7 recurrences and there was no local recurrence. Median time to recurrence was 40.4 months. There were 14 cases of symptomatic cataract. Dose >30 Gy had hazard ratio of 3.47 for cataract (p = 0.026). Omitting lens protection showed hazard ratio of 4.10 (p = 0.008). Conclusions: RT achieves excellent local control of ocular MALT lymphoma. Consideration of RT-related factors such as lens protection and radiation dose at the stage of RT planning may reduce the risk of RT-induced cataract after radiotherapy.

Effects of Antithyroid Drugs on Accidentally Internal Contamination of Iodine-131 (Iodine-131 체내오염 사고에 대한 항갑상선제의 효과)

  • Chung, In-Yong;Kim, Tae-Whan;Chin, Soo-Yil;Yun, Taik-Koo
    • Journal of radiological science and technology
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    • v.11 no.1
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    • pp.63-69
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    • 1988
  • In case of occuring the atomic energy accidents the proper medical treatments should be necessary. As the aim of the basic data for protective actions, the present studies were carried out to evaluate the decontamination of radioiodine by the administration of the antithyroid drugs (KI, NaI) and isotonic saline. Some recommended methods of decorporating radioiodine were investigated using 450, NIH-GP mice, each injected intraperitoneally with $1{\mu}Ci$ of $NaI^{131}$ as the internal contamination and treated with 2mg/0.2ml-saline of NaI and 2.6mg/0.2ml-saline of KI as the antithyroid drugs. Accordingly, effects of antithyroid drugs for internal contamination were: 1. Administration of NaI and KI caused to rapidly excrete internal radioiodine as the antithyroid drugs and decrease in whole body retention was reduced than in the saline group. 2. After internal contamination NaI and KI were to be administered for radioprotective effects as quickly as possible. 3. Decrease in body-retention made temporary shifts with enough fluids (water), however, as far as radioprotective effects is concerned, saline was not more significant than in the other group (NaI and KI). 4. Regarding to thyroid protective effects NaI, KI and saline were significant in effectively order.

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Effects of High Dose Irradiation on The Leukocyte Life Span (고선양(高線量) 방사선(放射線)이 백혈구(白血球) 수명(壽命)에 미치는 영향(影響))

  • Koh, Joo-Hwan;Chong, In-Yong;Kim, Yong-Kyu
    • Journal of Radiation Protection and Research
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    • v.9 no.2
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    • pp.67-75
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    • 1984
  • As a part of studies on acute effects of high dose irradiation the present report was carried out to evaluate the changes of the leukocyte life span in the Newzealand white male rabbits by a single whole body exposure to gamma rays from $^{60}Co$ teleirradiation unit. The exposure was done in dose levels of 100, 300, 550 and 1,000 rad to each experimental group of 10 rabbits. The life span and apparent half survival time of leukocytes, and the elution rate of leukocytes in the circulating blood were measured by McMillan method using $^{51}Cr$. 1. As a critical indicator of radiation hazards of the Newzealand male rabbits, the LD 50/30 and LD 100/30 after whole body exposure was estimated as 550 and 1,000 rads respectively. 2. The life span of leukocyte in the circulation after irradiation was slightly shortened in the 100 rad irradiated group, as compared with the unirradiated control group, but markedly shortened in the 300, 550 and 1,000 rads irradiated group. 3. After irradiation, decrease of leukocyte half survival time in the circulation showed the same pattern as that of leukocytes life span. 4. As the irradiation doses increased, the elution rate of $^{51}Cr$ loss from $^{51}Cr$ tagged leukocytes in the circulation were markedly increased gradually. 5. The life span shortening of leukocytes in the circulation after irradiation seems to occure by two processes of senescence acceleration and early destruction.

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Assessment of occupational radiation exposure of NORM scales residues from oil and gas production

  • EL Hadji Mamadou Fall;Abderrazak Nechaf;Modou Niang;Nadia Rabia;Fatou Ndoye;Ndeye Arame Boye Faye
    • Nuclear Engineering and Technology
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    • v.55 no.5
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    • pp.1757-1762
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    • 2023
  • Radiological hazards from external exposure of naturally occurring radioactive materials (NORM) scales residues, generated during the extraction process of oil and gas production in southern Algeria, are evaluated. The activity concentrations of 226Ra, 232Th, and 40K were measured using high-purity gamma-ray spectrometry (GeHP). Mean activity concentration of 226Ra, 232Th and 40K, found in scale samples are 4082 ± 41, 1060 ± 38 and 568 ± 36 Bq kg-1, respectively. Radiological hazard parameters, such as radium equivalent (Raeq), external and internal hazard indices (Hex, Hin), and gamma index (Iγ) are also evaluated. All hazard parameter values were greater than the permissible and recommended limits and the average annual effective dose value exceeded the dose constraint (0.3 mSv y-1). However, for occasionally exposed workers, the dose rate of 0.65 ± 0.02 mSv y-1 is lower than recommended limit of 1 mSv y-1 for public.

Development of a radiation thermometer for the adaptive steel plant (제철소 적응형 복사온도계 개발)

  • Park, Sang-Gug
    • Journal of the Korean Society of Industry Convergence
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    • v.5 no.3
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    • pp.173-178
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    • 2002
  • In this research, we have worked about the radiation thermometer which can be applied to the hazard circumstance such as steel plant. In the results, we have developed radiation thermometer of a measuring range $500-1500^{\circ}C$, accuracy ${\pm}0.1%$, repeatability ${\pm}0.1%$, resolution $0.2^{\circ}C$. We performed extensive field test for 6 months at the hot strip mill in steel plant. Through the test, we have confirmed the reliability of the developed pyrometer.

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Risk Assessment of 30 MeV Cyclotron Facilities (30 MeV 사이클로트론 시설 위험성 평가)

  • Jeong, Gyo-Seong;Kim, Chong-Yeal;Lee, Jin-Woo
    • Journal of Radiation Industry
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    • v.11 no.1
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    • pp.39-45
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    • 2017
  • A cyclotron is a kind of particle accelerator that produces a beam of charged particles for the production of medical, industrial, and research radioisotopes. More than 30 cyclotrons are operated in Korea to produce $^{18}F$, an FDG synthesis at hospitals. A 30-MeV cyclotron was installed at ARTI (Advanced Radiation Technology Institute, KAERI) mainly for research regarding isotope production. In this study, we analyze and estimate the items of risk such as the problems in the main components of the cyclotron, the loss of radioactive materials, the leakage of coolant, and the malfunction of utilities, fires and earthquakes. To estimate the occurrence frequency in an accident risk assessment, five levels, i.e., Almost certain, Likely, Possible, Unlikely, and Rare, are applied. The accident consequence level is classified under four grades based on the annual permissible dose for radiation workers and the public in the nuclear safety law. The analysis of the accident effect is focused on the radioactive contamination caused by radioisotope leakage and radioactive material leakage of a ventilation filter due to a fire. To analyze the risks, Occupation Safety and Health Acts is applied. In addition, action plans against an accident were prepared after a deep discussion among relevant researchers. In this acts, we will search for hazard and introduce the risk assessment for the research 30-MeV cyclotron facilities of ARTI.