• Title/Summary/Keyword: RVE 방법

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Inhibitory Effect of Rhus Verniciflua Extract on Lipid Peroxidation and Inflammatory Cytokines during Endurance Exercise Training (지구성 운동시 옻나무 추출액의 지질과산화 및 염증성사이토카인 억제효과)

  • Lee, Youn-Kyung;Kwon, Oh-Seon;Song, Young-Ju;Kim, Sea-Hyun;Kim, Pan-Gi;Ryu, Sung-Pil
    • Journal of Korean Society of Forest Science
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    • v.99 no.1
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    • pp.102-110
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    • 2010
  • This study was performed to find out the inhibitory effect of Rhus Verniciflua extract on lipid peroxidation and inflammatory cytokines during endurance exercise training for 8 weeks in rats. For this study, Sprague-Dawley rats were divided into 4 groups; sedentary (SED), exercise training (TRA), RVS extract ingestion (RVE), and RVS extract ingestion and exercise training (RVE-TRA). TRA and RVE-TRA were trained on treadmill with increasing speed gradually and administered 10 mL/kg/d of Rhus Verniciflua extract orally to RVE and RVE-TRA. In order to analyze antioxidant function, blood SOD (superoxide dismutase), GSH-Px (glutathione peroxidase), and MDA (malondialdehyde) were examined. And, analysis of inflammatory cytokines were examined using IL-6 (interleukin-6), TNF-${\alpha}$ (tumor necrosis factor-alpha), CRP (C-reactive protein), and NO (nitric oxide). SOD in TRA was significantly higher than SED and RVE (p<0.05), and RVE-TRA was highest among the groups (p<0.05). The MDA content of TRA, RVE and RVE-TRA were significantly lower than SED. GSH-Px activity of SED was significantly lower than other groups (p<0.05). IL-6 and TNF-${\alpha}$ content of RVE and RVE-TRA were significantly lower than SED and TRA (p<0.05). CRP concentration of SED was the lowest among groups (p<0.05). Finally, NO concentration of SED and TRA were higher than RVE and RVE-TRA (p<0.05). These results suggested that it is efficient for rats to reduce lipid peroxidation and induce anti-inflammatory by taking RVS extract during exercise training. Afterwards, if studies on the properties of RVS extract can be made with various ways, use of Rhus Verniciflua trees might be made widely which are growing naturally in mountains in Korea.

Multi-scale Process-structural Analysis Considering the Stochastic Distribution of Material Properties in the Microstructure (미소 구조 물성의 확률적 분포를 고려한 하이브리드 성형 공정 연계 멀티스케일 구조 해석)

  • Jang, Kyung Suk;Kim, Tae Ri;Kim, Jeong Hwan;Yun, Gun Jin
    • Composites Research
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    • v.35 no.3
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    • pp.188-195
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    • 2022
  • This paper proposes a multiscale process-structural analysis methodology and applies to a battery housing part made of the short fiber-reinforced and fabric-reinforced composite layers. In particular, uncertainties of the material properties within the microscale representative volume element (RVE) were considered. The random spatial distribution of matrix properties in the microscale RVE was realized by the Karhunen-Loeve Expansion (KLE) method. Then, effective properties of the RVE reflecting on spatially varying matrix properties were obtained by the computational homogenization and mapped to a macroscale FE (finite element) model. Morever, through the hybrid process simulation, a FE (finite element) model mapping residual stress and fiber orientation from compression molding simulation is combined with one mapping fiber orientation from the draping process simulation. The proposed method is expected to rigorously evaluate the design requirements of the battery housing part and composite materials having various material configurations.

Functionally Graded Structure Design for Heat Conduction Problems using Machine Learning (머신 러닝을 사용한 열전도 문제에 대한 기능적 등급구조 설계)

  • Moon, Yunho;Kim, Cheolwoong;Park, Soonok;Yoo, Jeonghoon
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.34 no.3
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    • pp.159-165
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    • 2021
  • This study introduces a topology optimization method for the simultaneous design of macro-scale structural configuration and unit structure variation to ensure effective heat conduction. Shape changes in the unit structure depending on its location within the macro-scale structure result in micro- as well as macro-scale design and enable better performance than using isotropic unit structures. They result in functionally graded composite structures combining both configurations. The representative volume element (RVE) method is applied to obtain various thermal conductivity properties of the multi-material based unit structure according to its shape change. Based on the RVE analysis results, the material properties of the unit structure having a certain shape can be derived using machine learning. Macro-scale topology optimization is performed using the traditional solid isotropic material with penalization method, while the unit structures composing the macro-structure can have various shapes to improve the heat conduction performance according to the simultaneous optimization process. Numerical examples of the thermal compliance minimization issue are provided to verify the effectiveness of the proposed method.

Evaluation of RVE Suitability Based on Exponential Curve Fitting of a Probability Distribution Function (확률 분포 함수의 지수 곡선 접합을 이용한 RVE 적합성 평가)

  • Chung, Sang-Yeop;Yun, Tae Sup;Han, Tong-Seok
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.30 no.5A
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    • pp.425-431
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    • 2010
  • The phase distribution in a multi-phase material strongly affects its material properties. Therefore, a proper method to describe the phase distribution of a material is needed. In this research, probability distribution functions, two-point correlation and lineal-path functions, are used to represent the probabilistic phase distributions of a material. The probability distribution function is calculated using a numerical method and is described as an analytical form via exponential curve fitting with three parameters. Application of analytical form of probability distribution function is investigated using two-phase polycrystalline solids and soil samples. It is confirmed that the probability distribution functions can be represented as an exponential form using curve fitting which helps identifying the applicability of a representative volume element(RVE).

Development of Modeling Technique and Material Prediction Method Considering Structural Characteristics of Woven Composites (직조 복합재료의 구조적 특성을 고려한 모델링 기법 및 물성 예측 기법 개발)

  • Choi, Kyung-Hee;Hwang, Yeon-Taek;Kim, Hee-June;Kim, Hak-Sung
    • Composites Research
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    • v.32 no.5
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    • pp.206-210
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    • 2019
  • As the use of composite materials of woven structure has expanded to various fields such as automobile and aviation industry, there has been a need for reliability problems and prediction of mechanical properties of woven composites. In this study, finite element analysis for predicting the mechanical properties of composite materials with different weaving structures was conducted to verify similarity with experimental static properties and an effective modeling method was developed. To reflect the characteristics of the weave structure, the meso-scale representative volume element (RVE) was used in modeling. Three-dimensional modeling was carried out by separating the yarn and the pure matrix. Hashin's failure criterion was used to determine whether the element was failed, and the simulation model used a progressive failure model which was suitable for the composite material. Finally, the accordance of the modeling and simulation technique was verified by successfully predicting the mechanical properties of the composite material according to the weave structure.

The Effect of Phrenic Nerve Paralysis After Pediatric Cardiac Surgery on Postoperative Respiratory Care (소아 심혈관 수술 후 발생한 횡격신경마비가 술후 호흡관리에 미치는 영향)

  • 윤태진;이정렬
    • Journal of Chest Surgery
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    • v.29 no.10
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    • pp.1118-1122
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    • 1996
  • From January 1990 through December 1995, 43 patients underwent diaphragmatic plication for the management of phrenic nerve palsy .complicating various pediatric cardiovascular surgery. Their mean age at plication was 11.1 months and sex ratio was 31 males to 12 females. In order of decreasing incidence, the primary cardiovascular procedures included modified Blalock-Taussig shunt (7), total correction for the Tetralogy of Falloff (7), arterial switch operation (6), unifocalization for the pulmonary atresia with VSD (3), modified Fontan operation (3), VSD patch closure (3) and others. The involved sides of diaphragm were right in 17, left in 2) and bilateral in 3. Extensive pericardial resection with electocauterization of resected margin was thought to be the most common cause of phrenic nerve palsy (20). The interval between primary operation and plication ranged from the day of operation to 98 days (median 11 days). The methods of plication were central pleating technique(plication with phrenic nerve branch preservation) in 41, and other technique In 2. 10 patients died after plication (7: early, 3; late), and the causes of death were thought to be unrelated to plication itself. Among the 36 early survivors, extubation or cessation of positive pressure ventilation could be accomplished between 1 and 24 days postoperatively(mean : 4.5). Cumulative follow-up was 92 patient years without major complications. Postoperative follow-up fluoroscopy was performed in 6 patients, and the location and movement of plicated diaphragms were satisfactory in 5 patients. We concluded that diaphragmatic plication with preservation of phrenic n rve branch could lead to cessation of positive pressure ventilation and complete recovery of diaphragmatic function in the long term, unless the phrenic nerve was irreversibly damaged.

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