• Archives of Plastic Surgery
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• 제38권3호
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• pp.295-299
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• 2011

Purpose: It is generally believed that alopecia is caused by various factors such as scars, stress, genetical factors, androgens, etc. Androgenic alopecia is one of the most common cause of alopecia and found mainly in males. Propecia (Merck & Co., USA) and Minoxidil (McNEIL-PPC, Inc, USA) were the drugs approved from FDA for treatment of androgenic alopecia. Surgical treatments such as flap, tissue expansion, scalp reduction and hair transplantation can be considered if necessary. Hair micrograft techniques were developed for natural hair shapes and minimal adverse effect. There were attempts to measure the length of the forehead of the Korean young adults. However attempts to classify the shape and location of forehead hairline were rare. This study attempted to find out standard hairlines of young adults in their 20s & 30s and the result would be the guideline of the hairline in hair replacement surgery of male patients in their 40s & 50s. Methods: 200 male adults in 20s and 30s were photographed and measured the length of 11 vertical index lines to determine hairline. The indexes are the distances from hairline to intercanthal midpoint (A), to medial canthus (B), to upper eyelid fissure (C), to lower eyelid fissure (D), to lateral canthus (E) and distance from lateral highest point to medial lowest point, if the hairline is M-shape (F). Additionally, we classified the hairlines into 4 groups, M, horizontal, inverted U and irregular shapes. Results: The most common hairline of male adults in their 20s is inverted U-shape (53.3%), followed by horizontal-shape, M-shape, irregular-shape. In their 30s, inverted U-shape (59%) is followed by irregular-shape, M-shape, horizontal-shape. The M-shape is more frequently found in males in 30s than those in 20s. The mean values of the indexes in their 20s are as follows: A (76.14 mm), B (Rt: 75.78 mm, Lt:76.41 mm), C (Rt: 69.43 mm, Lt: 69.92 mm), D (Rt: 76.92 mm, Lt:77.46 mm), E (Rt: 64.16 mm, Lt: 64.73 mm), F (4.09 mm). Those in their 30s are as follows: A (76.13 mm), B (Rt: 76.114 mm, Lt: 76.02 mm), C (Rt: 69.87 mm, Lt: 70.37 mm), D (Rt: 77.37 mm, Lt: 77.58 mm), E (Rt: 69.63 mm, Lt: 69.85 mm), F (6.14 mm). Conclusion: The knowledge about human body measurement is indispensable to plastic surgeons. In this study, inverted U shape is the most common type of hairline in 30s, and similar distribution is found in 20s. The percentage of M shape in their 30s is elevated more than 10% compared to that in their 20s. The study of hairline shapes and 11 indexes of hairlines can be useful for planning of the hair transplantation and postoperative evaluation. This study being based on photogrammetry, there may be differences between actual distance of curved face and projected distance on flat photographs.

• 대한화학회지
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• 제35권2호
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• pp.111-118
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• 1991

기체 상태의 오존(0.5 torr)과 이산화황간의 반응속도를 연구하였다. 이산화황은 7∼22 torr 의 압력범위에서 90∼155$^{\circ}$C의 온도영역에서 반응시켰다. 오존과 이산화황의 반응속도는 이산화탄소와의 반응보다 빨리 진행되었다. 오존과 이산화황의 반응속도식은 -d(O$_3 )/dt = k _0 (SO _2 )(M)(O _3)+2k _1(SO_2 )(O _3$)였다. 이 속도식의 첫 항은 3분자 반응으로 낮은 온도에서 우세하게 진행되었으며, 속도상수 k$_0 =(9.35{\pm}8.6){\times}10^9e^{-(11.05{\pm}2.04)kcal/RT}(M^{-2}s^{-1}$)이다. 속도식의 두번째 항은 2분자 열분해 반응으로부터 유도된 주된 반응으로 속도상수 k$_1=(1.53{\pm}1.5){\times}10^{11}e^{-22.7 kcal/RT}$이다. 전 반응차수는 주로 2차 반응이며 3차 반응과 복합반응으로 진행되었다.

• Asian-Australasian Journal of Animal Sciences
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• 제13권6호
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• pp.842-844
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• 2000

Changes in respiration rate (RR), rectal temperature (RT), respiratory moisture loss (RML), packed cell volume (PCV) and haemoglobin (Hb) were monitored in 2 adults female goats each of the Saanen (S) and Toggenburg (T) breeds during 60 min of exercise (walking at 3 km/h) on a moving-belt treadmill on each of 6 alternate days. A significant $time{\times}breed$ interaction was observed for RR; mean values in Sand T after 60 min of exercise were 130 and 223 /min ($p{\leq}0.01$). The observed time x breed interaction for RT indicated that S was less stressed by exercise than T; mean values after 60 min exercise were 40.4 and $40.8^{\circ}C$ respectively ($p{\leq}0.01$). For RML, the $day{\times}breed$ interaction ($p{\leq}0.001$) indicated that while S had higher values on day 1, thereafter the values for T were higher. The $time{\times}breed$ interaction for RML/breath indicated that values for T declined more rapidly (from 9.4 to 3.1 mgjbreath) than those for S (from 8.3 to 4.1 mgjbreath; ($p{\leq}0.01$). PCV declined during exercise ($p{\leq}0.05$) by 5.5 percentage points. The exercise imposed was stressful in that it led to increases in RR, RT and RML. S was most tolerant of exercise in that it recorded lower values of RT. The fact that the RML/breath was higher during exercies in S apparently allowed it to compensate for a lower RR. Despite higher RR and RML, T also had a higher RT, suggesting either higher muscular heat production during exercise in that breed, or higher sweating losses in S.

• 한국세라믹학회지
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• 제20권2호
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• pp.129-134
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• 1983

MgO.$Al_2O_3$ polycrstalline spinel powder was subjected to vaporization over the temperature range of 1150-130$0^{\circ}C$ under H2 atmosphere. Diffusion coefficient of oxygen ion through the spinel were calculated using the measure vaporization rates as follows : D=28.4 exp(-901500/RT) Reference data of the vaporization rates of MgO.$8Al_2O_3$ single crystal spinel were applied to the vaporiza-tion model proposed in this study and were calculated to give the oxygen ion diffusion coefficients over the tempera-ture 1700-195$0^{\circ}C$. The obtained diffusion coefficients are as follows: $D=3.20{\times}106$ exp(-155600/RT)

• 오토저널
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• 제31권3호
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• pp.64-69
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• 2009

• 미생물학회지
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• 제44권3호
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• pp.228-236
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• 2008

세포배양 유래 생물의 약품 생산 공정에서 다양한 바이러스가 오염된 사례가 있기 때문에 바이러스 안전성 검증이 필수적이다. Reovirus type 3 (Reo-3)는 동물 세포주와 동물 세포 배양 공정에 오염되는 대표적인 바이러스이다. 세포배양 유래 생물의약품의 Reo-3 안전성을 확보하기 위해, 세포주, 원료물질, 제조공정, 완제품에서 Reo-3를 정략적으로 검출하고, 제조공정에서 Reo-3 제거 검증을 위한 시험법으로 활용이 가능한 real-time RT-PCR 시험법을 확립하였다. Reo-3에 특이적인 primer를 선별하였으며, 형광염료 SYBR Green I을 사용하여 Reo-3 RNA 정략 검출 시험법을 최적화하였다. 세포배양법에 의한 감염역가와 비교한 결과 real-time RT-PCR 민감도는 $3.2{\times}10^0\;TCID_{50}/ml$이었다. 확립된 시험법의 신뢰성(reliability)을 보증하기 위해 시험법 검증을 실시한 결과 특이성(specificity)과 재현성(reproducibility)이 우수함을 확인하였다. 확립된 real-time RT-PCR을 생물의약품 제조공정 검증에 적용할 수 있는지 확인하기 위하여 인위적으로 Reo-3를 오염시킨 CHO 세포에서 Reo-3 검출 시험을 실시한 결과 Reo-3를 감염시킨 CHO 세포와 세포배양 상청액에서 Reo-3를 정략적으로 검출할 수 있었다. 또한 바이러스필터 공정에서 Reo-3제거 효과를 감염역가 시험법과 비교 검증한 결과 더 빠른 시간에 동일한 결과를 얻을 수 있었다. 위와 같은 결과에서 확립된 Reo-3 real-time RT-PCR 시험법은 생물의약품 안전성 보증을 위한 세포주 검증, 생물의 약품 생산 공정 검증, 바이러스 제거 공정 검증 등에서 감염 역가 시험법을 대신할 수 있는 신속하고, 특이성과 민감성이 우수한 시험법임을 확인하였다.

• Journal of Microbiology and Biotechnology
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• 제22권12호
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• pp.1776-1781
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• 2012

Multiple viruses such as Lily symptomless virus (LSV), Lily mottle virus (LMoV), and cucumber mosaic virus (CMV) are the most prevalent viruses infecting lilies in Korea. Leaf samples and bulbs showing characteristic symptoms of virus infection were collected from Gangwon, Chungnam, and Jeju provinces of Korea in 2008-2011. Coat protein (CP) genes of LSV and LMoV were amplified from collected samples by reverse transcription-polymerase chain reaction (RT-PCR) and cloned into a pET21d(+) expression vector to generate recombinant CPs. The resulting carboxy-terminal His-tagged CPs were expressed in Escherichia coli strain BL21(DE3) by isopropyl-1-thio-${\beta}$-D-galactoside induction. The recombinant proteins were purified using Ni-NTA agarose beads, and the purified proteins were used as an immunogen to produce polyclonal antibodies in rabbits. The resulting polyclonal antisera recognized specifically LSV and LMoV from infected plant tissues in Western blotting assays. Indirect enzymelinked immunosorbent assay and immunocapture RT-PCR using these polyclonal antisera were developed for the sensitive, efficient, economic, and rapid detection of Lily viruses. These results suggest that large-scale bulb tests and economic detection of Lily viruses in epidemiological studies can be performed routinely using these polyclonal antisera.

• Journal of Ginseng Research
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• 제12권2호
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• pp.158-163
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• 1988

고려인삼의 묘를 GA, 2,4-D 및 B-9로 처리하여 암하에서 생육시켰다. 생장효율($E_1$ = St/Ro, $E_2$ = St/(Ro-Rt), $E_3$ = (Ro- Rt)/ Ro, 여기서 St는 지상부중, Ro와 Rt는 초기와 일정시간 후의 뿌리의 무게임)과 기타 관련된 요인 및 상호관계를 조사하였다. $E_1$과 $E_3$는 온도변화에 이차식 관계를 보인 반면 $E_2$는 부의 직선 상관을 보였다. $E_1$은 $E_2$보다 $E_3$에 더 의존하였다. $E_2$와 $E_3$값은 거의 같았다. $E_2$는 전에 보고된 값보다 커서 뿌리간 큰 차이가 있음을 나타낸다. GA는 고온역에서 $E_2$와 $E_3$값을 증대시켰으며 B-9은 모든 온도에서 $E_3$를 크게 감소시켰고고 저온역에서 $E_2$를 감소시켰다. 지상부중은 대부분의 생장조절제와 온도에서 기질량과 유의정상관을 보였으며 몇경우에는 호흡소모량과 유의정상관을 보였다. 호흡소모량은 저온역에서만 $E_1$ 및 $E_3$와는 유의정상관을 $E_2$와는 유의부상관을 보였다.

• 한국식품과학회지
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• 제12권4호
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• pp.285-291
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• 1980

아끼바레 및 밀양 23호의 수화 및 취반속도를 비교하였다. 수화속도는 $10{\sim}40^{\circ}C$ 범위에서 무게증가로서 측정한 결과, 수화시간의 평방근의 비례하였다. 확산 계수는 Arrhenius 방정식으로 표시되었다. 아끼바레의 확산계수는 $3.151{\times}10^{-3}\exp(-4000/RT)$, 밀양 23호는 $5.853{\times}10^{-3}\exp(-5700/RT)$로 표시될 수 있었다. 취반속도는 밀양 23호가 아끼바레보다 빨랐으며 취반활성화에너지는 $90{\sim}100^{\circ}C$에서 밀양 23호가 아끼바레보다 다소 높았다. 밥의 조직특성은 밀양 23호의 부착성이 아끼바레보다 높았고, 아밀로 그라프의 점도도 밀양 23호가 높았다.

• The Journal of the Acoustical Society of Korea
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• 제25권3E호
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• pp.95-100
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• 2006

The present study presents the design procedures and the acoustic properties of the main hall of Ansan Cultural Arts Center in Korea which has opened in 2004. The acoustic design values are compared with the measured acoustic properties of the completed multi-purpose hall. Acoustic design criteria were suggested in the design stage through the 3-dimentional computer simulations. The acoustic parameters including SPL, RT, C80, $D_{50}$M, RASTI were measured in the hall after completed. Acoustic measurements were carried out in the 40 measurement points using MLS sound source signal in 4 different sound source points. The results show the even distribution of sound levels within the 2.0dB of difference among all seats. The reverberation time of 1.66sec was measured which is similar to the objective value of 1.65 sec in empty states. It was also found that average C80 values lie in the objective extents of C80 from -1 to 3dB and average D50 value of 54 was measured. Thus, it is concluded that the hall can be used as a multi-purpose hall with a suitable acoustic conditions.