• Title/Summary/Keyword: RS 4형

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Effects of interaction between SLC12A3 polymorphism, salt-sensitive gene, and sodium intake on risk of child obesity (소금민감성 SLC12A3 유전자 다형성에 따른 나트륨섭취가 소아비만에 미치는 영향)

  • Jung, Joohyun;Lee, Myoungsook
    • Journal of Nutrition and Health
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    • v.50 no.1
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    • pp.32-40
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    • 2017
  • Purpose: Obesogenic environments in children, in particular excessive intake of sodium, generate hypertension, which is a major risk factor for chronic diseases. Methods: In all, 725 children, 379 boys and 373 girls, aged 8~9 years were recruited from seven elementary schools in Kuro-ku, Seoul. To evaluate whether or not obesity risk was modulated by salt-sensitive genes, Solute Carrier Familiy 12 member 3 (SLC12A3) was used as the target. After children were assigned into obese (BMI > 85 percentile) or non-obese groups, anthropometry, blood biochemistry, and dietary intakes were measured according to the genotypes GG (wild) or GA+AA (hetero+mutant). Results: Without gender differences, high TG and low HDLc were detected in the obese group compared to the non-obese group. Regardless of obesity, weight gain and blood pressure (BP) increased in the SLC12A3 GA+AA genotype rather than in the GG type. HDLc was associated with obesity risk without genotype difference. Odd ratios for risk of obesity were 15.57 (95% CI 2.192~110.654), 22.84 (95% CI 1.565~333.469), and 9.32 (95%CI 1.262~68.817) in boys and girls with GA+AA genotypes as sodium intake increased above 4,000 mg/day. Dietary calcium, sodium, folate, and vit C were associated with obesity risk according to gender or genotype differences. Since high folate intake reduced obesity risk in only boys with GG type. Risk for overweight and obesity increased in boys with GA+AA genotypes and dietary habits with high sodium and cholesterol and low folate. Conclusion: The A allele of SLC12A3 rs11643718 was sensitive to development of obesity in children as sodium intake increased.

A Study on the Application of the Spatial Information Services for Water Hazard Information Services Platform (수재해 정보 플랫폼을 위한 공간정보서비스 활용 방안 연구)

  • LEE, Jeong-Ju;CHAE, Hyo-Sok;HWANG, Eui-Ho;KIM, Dong-Young
    • Proceedings of the Korea Water Resources Association Conference
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    • 2015.05a
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    • pp.639-639
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    • 2015
  • 최근 지식정보 사회는 IT가 핵심 구성요소인 스마트 사회로 변모하고 있으며, 인간과 사물 간 의사소통에서 사물과 사물 간 의사소통까지 확장하고, IT간 융합에서 나아가 타 산업과 융합하는 지능형 사회로 나아가고 있다. '공간'에 대한 정보는 '시간'과 함께 인간이 생활하는데 있어 반드시 알아야 하는 가장 근본적인 정보로써, 공간에서 발생하는 정보를 기반으로 다른 사람들과 소통을 하고 목적을 충족함으로써 삶의 질을 향상시킨다. 현대 사회에서 공간정보는 중요한 인프라 가치를 증대시키므로 새로운 사회 패러다임 전환을 위한 필수적인 요소라 할 수 있다. 따라서 본 연구에서는 수재해 정보 플랫폼 구현에 앞서 사용자의 니즈를 만족시키고 효용가치 증대가 가능하도록 공간정보서비스 활용 방안 연구를 하고자 한다. 공간정보는 시대의 흐름에 따라 형태 및 생산?활용방법이 달라졌으나 항상 중요한 정보로 인식되어 왔으며, 미래 공간정보는 단순 콘텐츠 영역을 뛰어넘어 상황(Context)정보까지 범위를 확장하였다. (1)미국의 공간정보는 시설, 기록관리 및 지도와 같은 공공분야에서 현재는 업무통합관리, 의사결정지원 등에서 데이터 웨어하우스(Data Warehouse)로서의 역할 담당한다. (2)일본은 아시아 최고의 원천기술력을 보유하고 있으며, 높은 수준의 GIS, RS(위성항측), ITS(지능형 교통 시스템) 기술을 기반으로 하고 있다. (3)영국은 지리정보시스템과 공공서비스를 접목하여 시민의 요구에 부응하는 고객맞춤형서비스 제공을 국가정보화의 우선과제로 선정하고 있다. (4)우리나라는 초고속통신망과 모바일 기술 등 세계 최고 수준의 인프라를 확보하고 있어, 이러한 인프라 기반융 복합 공간정보서비스를 이용하는데 안정적인 기반을 확보하고 있다. 본 연구는 국내외 공간정보서비스의 패러다임 변화 및 추진 동향 등을 제시하였으며, 수재해정보 플랫폼 활용에 능동적 적극적으로 접근할 수 있는 기반을 마련하였다. 공간정보서비스를 활용하여 커뮤니케이션 강화, 수재해 정보 서비스의 효율성 증진, 재해부문 선진화 측면에서 발전적 영향을 미칠 수 있으며, 특히 각종 현안에 대한 미래 예측 및 대응에 기여할 것으로 판단된다.

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Application of Snowmelt Parameters and the Impact Assessment in the SLURP Semi-Distributed Hydrological Model (준 분포형 수문모형 SLURP에서 융설매개변수 적용 및 영향 평가)

  • Shin, Hyung-Jin;Kim, Seong-Joon
    • Journal of Korea Water Resources Association
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    • v.40 no.8
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    • pp.617-628
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    • 2007
  • The purpose of this paper is to prepare snowmelt parameters using RS and GIS and to assess the snowmelt impact in SLURP (Semi-distributed Land Use-based Runoff Process) model for Chungju-Dam watershed $(6,661.5km^2)$. Three sets of NOAA AVHRR images (1998-1999, 2000-2001, 2001-2002) were analyzed to prepare snow-related data of the model during winter period. Snow cover areas were extracted using 1, 3 and 4 channels, and the snow depth was spatially interpolated using snowfall data of ground meteorological stations. With the snowmelt parameters, DEM (Digital Elevation Model), land cover, NDVI (Normalized Difference Vegetation Index) and weather data, the model was calibrated for 3 years (1998, 2000, 2001), and verified for 1 year (1999) using the calibrated parameters. The average Nash-Sutcliffe efficiencies for 4 years (1998-2001) discharge comparison with and without snowmelt parameters were 0.76 and 0.73 for the full period, and 0.57 and 0.19 for the period of January to May. The results showed that the spatially prepared snow-related data reduced the calibration effort and enhanced the model results.

Highly Sensitive MEMS-Type Micro Sensor for Hydrogen Gas Detection by Modifying the Surface Morphology of Pd Catalytic Metal (Pd 촉매금속의 표면형상 변형에 의한 고감도 MEMS 형 마이크로 수소가스 센서 제조공정)

  • Kim, Jung-Sik;Kim, Bum-Joon
    • Korean Journal of Materials Research
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    • v.24 no.10
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    • pp.532-537
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    • 2014
  • In this study, highly sensitive hydrogen micro gas sensors of the multi-layer and micro-heater type were designed and fabricated using the micro electro mechanical system (MEMS) process and palladium catalytic metal. The dimensions of the fabricated hydrogen gas sensor were about $5mm{\times}4mm$ and the sensing layer of palladium metal was deposited in the middle of the device. The sensing palladium films were modified to be nano-honeycomb and nano-hemisphere structures using an anodic aluminum oxide (AAO) template and nano-sized polystyrene beads, respectively. The sensitivities (Rs), which are the ratio of the relative resistance were significantly improved and reached levels of 0.783% and 1.045 % with 2,000 ppm H2 at $70^{\circ}C$ for nano-honeycomb and nano-hemisphere structured Pd films, respectively, on the other hand, the sensitivity was 0.638% for the plain Pd thin film. The improvement of sensitivities for the nano-honeycomb and nano-hemisphere structured Pd films with respect to the plain Pd-thin film was thought to be due to the nanoporous surface topographies of AAO and nano-sized polystyrene beads.

A Study on Composition of Position Detection System using GPS (GPS 위치검지시스템 구성에 관한 연구)

  • Han, Young-Jae;Park, Choon-Soo;Lee, Tae-Hyoung;Kim, Ki-Hwan;Eun, Jong-Phil
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.21 no.2
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    • pp.151-155
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    • 2008
  • KHST(Korean High Speed Train) has been utilized the total measurement system which evaluates the efficiency and a breakdown of the vehicle and it's results effect to secure reliability of the vehicle. Generally KHST has been received pulse signals from the wheel. It calculates the travel distance after counter the signals to confirm location information of the vehicle. However, there is a limit to measure the location of the vehicle due to slip, slide and the wheel attrition. We have developed a new measurement system by using GPS to complement those errors. In general, GPS receivers are composed of an antenna, tuned to the frequencies transmitted by the satellites, receiver-processors, and a highly-stable clock The GPS mounted on the roof of TT4 in KHST receives a signal from the RS232 communication port. It is connected to the network system in TT3 after converting with TCPIP communication. It is able to track the position of vehicle and synchronize the signal from different measurement system simultaneously. Therefore it is able to chase the fault occurrence, track inspection and electrical interruption at real-time situation more accurately. There is not an error coursed by vehicle conditions such as slip and the slide.

Water Quality and Epilithic Diatom Community in the Lower Stream near the South Harbor System of Korean Peninsula (한반도 서남부 하천 하구역의 수질 및 부착돌말 군집 특성)

  • Kim, Ha-Kyung;Lee, Min-Hyuk;Kim, Yong-Jae;Won, Du-Hee;Hwang, Soon-Jin;Hwang, Su-Ok;Kim, Sang-Hoon;Kim, Baik-Ho
    • Korean Journal of Ecology and Environment
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    • v.46 no.4
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    • pp.551-560
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    • 2013
  • Environmental factors and epilithic diatom communities in the lower streams near the harbor region of South Korean peninsula were examined during no monsoon period in May 2013. The sampling of water and epilithic diatoms was conducted at both streams, 19 regulated streams (RS) that there are one or several dams constructed in the river system, and 19 un-regulated streams (US) that there are no dams within the river. A cluster analysis based on the number of species and abundance of epilithic diatoms through the stations, divided into three groups such as groups I (mainly US), II (mixed with US and RS) and III (mainly RS), respectively. Group I showed that water quality is good and high diversity of diatom, while Group II and III was water quality is relatively poor, but not differed in biomass of diatom from Group I. In addition, Group II that had high conductivity, nitrogen and phosphorus, was the lowest in diatom diversity among them. Dominant species were Nitzschia palea (17%) and Navicula seminuloides (11%) in Group I, Nitzschia inconspicua (19%) and Navicula perminuta (9%) in Group II, and Nitzschia inconspicua (15%) and Nitzschia palea (14%) in Group III, respectively. These taxa were widely distributed in brackish water, and not closely related with specific water quality, like eutrophic water. However, the groups II and III belonged to RS, had not only little biomass, but bad water quality such as high concentrations of nutrient and chlorophyll-a. Therefore, to determine the effect of dam construction on the lower water ecosystem, the planktonic algae, which can occur algal bloom in the estuary, also was considered to be a parallel investigation.

Strength and CO2 Reduction of Fiber-Reinforced Cementitious Composites with Recycled Materials (자원순환형 재료를 사용한 섬유보강 시멘트 복합체(FRCCs)의 강도 및 CO2 저감에 관한 연구)

  • Lee, Jong-Won;Kim, Sun-Woo;Park, Wan-Shin;Jang, Young-Il;Yun, Hyun-Do
    • Journal of the Korea Concrete Institute
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    • v.29 no.4
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    • pp.379-387
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    • 2017
  • The objective of this study is to develop sustainable PVA fiber-reinforced cementitious composites (FRCCs) that could exhibit comparable strength level to normal PVA FRCCs with no recycled materials. To evaluate mechanical properties of the FRCCs, compressive, flexural and direct tensile tests were conducted. In addition to the test, to calculate amount of carbon dioxide ($CO_2$) emission at the stage of manufacturing the FRCCs, life cycle inventory data base (LCI DB) were referenced from domestic and Japan. From the test results, the mechanical properties such as compressive, flexural and direct tensile strengths were decreased as the replacement ratio of recycled materials increased. And it was determined that the amount of $CO_2$ emission was reduced for the specimens with higher water-binder ratio (W/B) and replacement ratios. It was also found that binder intensity ($B_i$) value was higher as replacement ratio of fly ash (FA) increased. This result means that larger amount of FA is need to deliver one unit of a given performance indicator (1 MPa of strength) of FRCCs compared to that of ordinary portland cement (OPC). As a result, it could be concluded that FRCCs with W/B 45% replaced by FA 25% and recycled sand (RS) 25% is desirable for both target performance and $CO_2$ emission.

Open Heart Surgery of Ventricular Septal Defect in Infancy (영아기 심실중격결손의 개심술)

  • 조준용;허동명
    • Journal of Chest Surgery
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    • v.29 no.3
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    • pp.271-277
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    • 1996
  • In selected cases, early corrective surgery is indicated in the management of infants having large ventricular septal defects. The risk of any surgical procedure in infancy is acknowledged to be great and should be avoided whenever possible. However this greater surgical risk is justified when the patient presents with intractable congestive heart failure, severe pulmonary hypertension, marked growth retardation, and recurrent prolonged lower respiratory infections. We analyzed 31 patients with ventricular septal defect in infancy who underwent surgical correction from January 1991 through December 1994. Age ranged from 6 months to 12 months with mean age of 9.2 months. Of the thirty-one patients, 23 patients were male and 8 patients were female. Mean body weight was 7. 4kg. The most common type of ventricular septal defect was perimembraneo s (64.5%). Associated cardiac anomalies were found in 17 patients (55.8%). Mitral regurgitation was the most commonly associated cardiac anomaly (16.1 %) and followed by patent ductus arteriosus (12.9%). When cardiac catheterization data were analysed, the most common range of Qp/qs, RpiRs, Pp/ps were 2.1∼ 3.0, 1-0.25, above 0.70 respectively. Among the indications of surgical correction, there were pulmonary hypertension in 20 patients, congestive heart failure in 3 patients, intractable respiratory infection in 10 patients and growth retardation in 14 patients. The most common surgical approach and method for closure of ventricular septal defect .were right atriotomy (58%) and Dacron patch closure (94%). Postoperative complications occurred in 10 cases (32%) and overall mortality was 12.9% (4 cases). All operative deaths in this series occurred in infants under the age of 8 months and weight of 8 kilograms.

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Analysis of In-Cylinder Flow Characteristics of a High Speed D.I. Diesel Engines (고속 직접분사식 디젤 엔진의 실린더내 유동 해석)

  • Park, Sang-Chan;Ryu, Jae-Deok;Lee, Gi-Hyeong
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.26 no.9
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    • pp.1276-1283
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    • 2002
  • Recently, HSDI (High Speed Direct Injection) diesel engine has been spotlighted as a next generation engine because it has a good potential for high thermal efficiency and fuel economy. This study was carried out to investigate the in-cylinder flow characteristics generated in a 4-valve small diesel cylinder head with a tangential and helical intake port. The flow characteristics such as coefficient of flow rate(Cf), swirl ratio (Rs), and mass flow rate (ms) were measured in the steady flow test rig using the impulse swirl meter and the analysis of in-cylinder flow field was conducted by experiment using the PIV and calculation using the commercial CFD code. As the results from steady flow test indicate, the mass flow rate of the cylinder head with a short distance between the two intake ports is increased over 13% than that of the other head. However, the non-dimensional swirl ratio is decreased approximately 15%. From in-cylinder flow characteristics obtained by PIV and CFD calculation, we found that the swirl center was eccentric from the cylinder center and the velocity distribution became uniform near the TDC. In addition, the results of the calculation are good agreement with the experimental results.

Framework for Information Integration and Customization Using Ontology and Case-based Reasoning (온톨로지 및 사례기반추론을 이용한 맞춤형 통합 정보 생성 프레임워크의 제안)

  • Lee, Hyun-Jung;Sohn, M-Ye
    • Journal of Intelligence and Information Systems
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    • v.15 no.4
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    • pp.141-158
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    • 2009
  • The requirements of knowledge customization have increased as information resources have become more various and the numbers of the resources are increased. Even if the method for collecting the information has improved like Really Simple Syndication (RSS), information users are still struggling for extracting and customizing the required information through the Web. To reduce the burden, we offer the dynamic knowledge customization framework by using ontology-based CBR. The framework consisting of three phases is comprised of the conversion phase of web information as a machine-accessible case, the extraction phase to find a case appropriate for information users' requirements, and the case customization phase to create knowledge depending on information user's requirements. Newly, the dynamic and intensity-based similarity is adopted to support timely dynamic change of users' requirements. The framework has adopted to create traveler's knowledge to the level users wanted.

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