• Journal of Information Technology Applications and Management
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• 제12권4호
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• pp.25-31
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• 2005

We know that the Hurst Exponent (HE) is a real number in [0, 1] which denotes randomness of time series. in this research, we suggest non-linear analysis of human biological signals through HE. The feasibility of human biological signals using inductive incitement provides Some diagnosis for active treatment. In our experiment, we measured the heartbeat through the MCG, 29 healthy and 34 abnormal subjects ostensibly. The raw data of acupuncture incitement are supported by opinions of gross examination and pathological diagnosis. The mean values of HE are 0.345, 0.755 and 0.805 for the periods of before, during and after acupuncture treatment, respectively in case of abnormal subjects. On the other hand, the mean values, 0.808, 0.797 and 0.785 are for normal cases, correspondingly. From this data, we show that HE is very significant in abnormal controls according to an acupuncture incitement, and the incitement effect is evidently extracted in abnormal subjects. But, in normal subjects, the incitement effect is meaningless.

• 인터넷정보학회논문지
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• 제10권5호
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• pp.107-116
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• 2009

본 논문에서는 심전도 신호로부터 부정맥을 진단하는 방법으로 심박수 변이도와 퍼지 신경망을 이용하는 방안을 제시하고 있다. 제안한 부정맥 진단 알고리즘은 32개 RR 간격의 심박수 변이도, 즉 평균 25초 내외의 심박수 변화를 이용하여 부정맥을 진단하는 알고리즘이다. 부정맥 진단 알고리즘은 32개 RR 간격을 이용하여, 통계적 특징 6개를 추출한 후, 가중 퍼지소속함수 기반 신경망으로 학습하여 정상 구간과 부정맥 구간을 분류한다. 부정맥 진단 알고리즘은 Tsipouras 논문군(48개 레코드)에서 SE와 SP 각각 80% 이하의 성능을 보이는 기존연구와는 달리, SE는 88.75%, SP는 82.28%, 전체 분류율은 86.31%의 신뢰성 있는 결과를 나타낸다.

• 한국농공학회논문집
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• 제60권1호
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• pp.111-120
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• 2018

The purpose of this study was to develop a ridge regression (RR) model to estimate BOD and TP load using runoff weighted value. The concept of runoff weighted value, based on distributed curve-number (CN), was introduced to reflect the impact of land covers on runoff. The estimated runoff depths by distributed CN were closer to the observed values than those by area weighted mean CN. The RR is a technique used when the data suffers from multicollinearity. The RR model was developed for five flow duration intervals with the independent variables of daily runoff discharge of seven land covers and dependent variables of daily pollutant load. The RR model was applied to Heuk river watershed, a subwatershed of the Han river watershed. The variance inflation factors of the RR model decreased to the value less than 10. The RR model showed a good performance with Nash-Sutcliffe efficiency (NSE) of 0.73 and 0.87, and Pearson correlation coefficient of 0.88 and 0.93 for BOD and TP, respectively. The results suggest that the methods used in the study can be applied to estimate pollutant load of different land cover watersheds using limited data.

• 한국멀티미디어학회논문지
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• 제21권12호
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• pp.1370-1378
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• 2018

There is a problem to measure neutral bio-signals during sleep because of inconvenience of attaching lots of sensors. In this study, we measured single electrocardiogram(ECG) signal and analyzed the correlation with sleep. After R-peak detection from ECG signal, we extracted 9 features from time and frequency domain of heart rate variability(HRV). Mean of HRV, RR intervals differing more than 50ms(NN50), and divided by the total number of all RR intervals(pNN50) have significant differences in each sleep stage. Specially, the mean HRV has an average of 87.8% accuracy in classifying sleep and awake status. In the future, the measurement ECG signal minimizes inconvenience of attaching sensors during sleep. Also, it can be substituted for the standard sleep measurement method.

• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 2003년도 제8차 학술대회 초록집
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• pp.44-44
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• 2003

To determine feasibility of contrast-enhanced MRI (co-MRI) at true end-diastole (ED) free from limitation of time for inversion-recovery and trigger window for quantifying transmural extent of infarction. 대상 및 방법： MRI was performed in 18 patients with myocardial infarction. Cine imaging and co-MRI with same registered slices in short axis were peformed. To allow true ED co-MRI, ECG synchronization should use two RR-intervals for one acquisition of a segment of k-space by setting the heart rate to half that of the true heart rate. Trigger delay time was adjusted to the RR-interval for imaging at ED and to the sum of RR-interval plus the time between R-wave and the end-systole (ES) determined in cine images for imaging at ES.

• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 2003년도 제8차 학술대회 초록집
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• pp.91-91
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• 2003

To determine feasibility of contrast-enhanced MRI (co-MRI) at true end-diastole (ED) free from limitation of time for inversion-recovery and trigger window for quantifying transmural extent of infarction. 대상 및 방법： MRI was peformed in 18 patients with myocardial infarction. Cine imaging and co-MRI with same registered slices in short axis were performed. To allow true ED co-MRI, ECG synchronization should use two RR-intervals for one acquisition of a segment of k-space by setting the heart rate to half that of the true heart rate. Trigger delay time was adjusted to the RR-interval for imaging at ED and to the sum of RR-interval plus the time between R-wave and the end-systole (ES) determined in cine images for imaging at ES.

• 대한화학회지
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• 제42권1호
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• pp.51-56
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• 1998

남조류 독성물질인 Microcystins은 자연계에 매우 미량 존재하기 때문에 이를 분리 및 정제하기가 쉽지 않다. 본 연구에서는 자연계에 존재하는 남조류 동결건조시료로부터 Microcystin RR과 LR을 분리 및 정제하는 새로운 방법을 개발하였다. 약 7.5g의 실리카겔을 정지상으로 사용하고 혼합용액인 ethyl acetate: iso-propanol:water(30: 45: 25)을 이동상으로 사용하는 open column system으로 시료를 전개한후 용액을 3mL간격으로 받아냈다. 받아낸 용액중의 Microcystin RR과 LR은 TLC와 HPLC(high performance Liquid Chromatography)를 이용하여 확인한 후 농축, 정제하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5161-5166
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• 2014

Our aim was to access the association between recreational physical activity (RPA) and risk of ovarian cancer (OC). The studies were retrieved from the PubMed and Embase databases up to February 20th, 2014. Risk ratios (OR) and 95% confidence intervals (CI) were used to estimate effect sizes. Random-effects or fixed-effects models were used to pool the data. The trim and fill method was applied for sensitivity analysis. Begg's rank correlation test and Egger's regression asymmetry test were employed to assess the publication bias. A total of 6 studies (435398 participants including 2983 OC patients) were included in this meta-analysis. The overall estimate indicated that there was weakly inverse association between RPA and OC risk (RR=0.90, 95%CI: 0.72-1.12, p=0.335). Meanwhile, for prospective cohort studies, a result consistent with the overall estimate was obtained (RR=1.12, 95% CI: 0.88-1.42, p=0.356). However, for case control studies, the pooled estimate of RR was 0.76 (95%CI: 0.64-0.90, p=0.002), indicating a clear significant association between RPA and OC risk. In addition, the sensitivity analysis indicated a significant link between RPA and risk of OC after removing Lahmann's study (RR=0.80, 95% CI: 0.68-0.93, p=0.004). No significant publication bias was found (Begg's test: p=1.00; Egger's test: p=0.817). In conclusion, our meta-analysis indicated a weakly inverse relationship between RPA and the occurrence of OC.

• Asian Pacific Journal of Cancer Prevention
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• 제14권4호
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• pp.2515-2519
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• 2013

The standard surgery for early-stage endometrial cancer is total abdominal hysterectomy (TAH), while total laparoscopic hysterectomy (TLH) is less invasive and assumed to be associated with lower morbidity. This meta-analysis was performed to investigate the effects of TLH versus TAH in women with early-stage endometrial cancer. We searched the PubMed, EMBASE, CBM and Cochrane Review databases for randomized trials assessing the effects of TLH versus TAH in women with early-stage endometrial cancer. The relative risks (RR) with 95% confidence intervals (CIs) from each study were pooled using meta-analysis. In our study, 9 randomized trials with a total of 1,263 patients were included. Meta-analyses showed that TLH was associated with lower risks of major complications (RR = 0.53, 95%CI 0.29-0.98, P = 0.042), total complications (RR = 0.59, 95%CI 0.42-0.82, P = 0.002) and postoperative complications (RR = 0.57, 95%CI 0.40-0.83, P = 0.003). However, there were no obvious differences in risks of intra-operative complications (RR = 0.98, 95%CI 0.62-1.55, P = 0.919) and mortality (RR = 0.96, 95%CI 0.66-1.40, P = 0.835). In conclusion, our results provide new evidence of a benefit for TLH over TAH in terms of major complications, total complications and postoperative complications in endometrial cancer patients.

• Industrial Engineering and Management Systems
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• 제12권4호
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• pp.380-388
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• 2013

Large variation in electrocardiogram (ECG) waveforms continues to present challenges in defining R-wave locations in ECG signals. This research presents a procedure to extract the R-wave locations by forward-backward (FB) algorithm and classify the arrhythmic beat conditions by using RR intervals. The FB algorithm shows forward and backward searching rules from QRS onset and eliminates lower-amplitude signals near the baseline using a statistical process control concept. The proposed algorithm was trained the optimal parameters by using MIT-BIH arrhythmia database (MITDB), and it was verified by actual Holter ECG signals from a local hospital. The signals are classified into normal (N) and three arrhythmia beat types including premature ventricular contraction (PVC), ventricular flutter/fibrillation (VF), and second-degree heart block (BII) beat. This work produces 98.54% accuracy in the detection of R-wave location; 98.68% for N beats; 91.17% for PVC beats; and 87.2% for VF beats in the collected Holter ECG signals, and the results are better than what are reported in literature.