• 대한의용생체공학회:의공학회지
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• 제31권1호
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• pp.56-66
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• 2010

The various total replacement artificial discs have developed because spinal fusion has shown a lesser mobility of an operated segment and an accelerated degeneration at adjacent discs. But almost artificial discs have not yet been reached on the substitute surgery of fusion because many problems such as those clinical success rates were not more than them of fusion have not solved. In this paper, vertically inserted assemble-screw fixture in vertebrae was proposed to improve the fixed capability of artificial disc. And also, to evaluate the design suitability of newly designed screw-type, including fixtures of commercial discs such as wedge and plate type, the 1/4 finite element model with a vertebra and various implanted fixtures were generated, and next, 3 bending motions such as flexion, bending and twisting under the moment of 10Nm and compression under the force of 1000N were considered, respectively and finally, FE analyses were performed. Results of three fixture types were compared, such as Range of Motion and maximal stress, and so on. For ROM, the screw type was average 58% less than the wedge type and was average 42% less than the plate type under all loading conditions. For average stress ratio at closer nodes between vertebra and each fixture, the wedge type was the lowest as minimum 0.02 in twisting, screw types were the highest as maximum 0.28 in compression. As the results of using cement material, it was predicted that the instability problem of the wedge type was better solved. The screw type which could be increased by implanting depth according to the number of assembling mid screws, showed that the decreased tendency of ROMs and maximal cancellous bone stresses. In further study, controlling the number of assembling screws that was suitable for a patient's bone quality, development of surgical tools and keeping on design supplementations, which will be able to develop the competitive artificial disc.

• 한국수산과학회지
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• 제50권2호
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• pp.183-194
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• 2017

The catch of Todarodes pacificus in the Yellow Sea is commonly known as the winter cohort. So, to understand the transport process of winter cohort of T. pacificus, and to identify whether the simulated individuals which are transported directly into the Yellow Sea (YS) influence these resources immediately, we conducted a Lagrangian-particle-tracking numerical experiments of T. pacificus from 2005 to 2010 using LTRANS and ROMS. The results show that: (1) Most of the released individuals spread out to the open sea by the Kuroshio and the Tsushima Warm Current around 30 days after release. (2) Unlike the hypothesis proposed by Rosa et al. (2011), Around $30-33N^{\circ}$ near Jeju Island simulated the initial position (3) About 0.01% of individuals released in December were transported solely into the YS around 15 days after release. However there were no surviving individuals due to the low temperature less than $12^{\circ}C$. Also the variation of individuals entered into the YS was not significantly correlated with it in YS catches during the experimental period. Therefore, the most of resources in the YS is assumed to be more influenced by diverse factors of the Pacific Ocean and East Sea than the direct transport in the YS of winter cohort.

• PNF and Movement
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• 제15권3호
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• pp.237-246
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• 2017

Purpose: The purpose of this study was to investigate the effects of forward-and-backward shift trunk exercise using a proprioceptive neuromuscular facilitation (PNF) diagonal pattern in a closed kinematic chain exercise on the upper limb function and activity of daily living (ADL) in a stroke patient. Methods: One subject participated in this study. The study used a reversal A-B-A' design, where A and A' were the baseline period (no intervention), and B was the intervention period. The intervention was a forward-and-backward trunk shift exercise, using a PNF diagonal pattern on both a stand-on-hand position and a quadruped position of closed kinematic chain exercises, for 20 min per day for 2 weeks. The range of motion (ROM) of the shoulder joint was measured and a Fugl-Meyer assessment of upper extremity (FMA-UE) and a functional independence measure (FIM) were performed to measure upper limb function and activity of daily living (ADL). Results: ROMs of shoulder joint (flexion, extension, abduction, and external rotation) increased in the intervention phase. The FMA-UE score increased (from 28 to 36) in the intervention phase. The FIM score increased (from 20 to 25) in the intervention phase. These increases were maintained after intervention (Baseline II). Conclusion: These results suggest that forward-and-backward shift trunk exercises using a PNF diagonal pattern in a closed kinematic chain exercise have a positive effect on stroke patients' upper limb function and ADL ability.

• 전자공학회논문지
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• 제54권7호
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• pp.29-35
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• 2017

본 논문에서는 고속 데이터 전송을 위해 orthogonal frequency division multiplexing (OFDM) 시스템에 적용 가능한 고속 fast Fourier transform (FFT) 프로세서를 제안하였다. 제안하는 FFT 프로제서는 높은 처리율을 만족하기 위해 mixed-radix 알고리즘과 8개의 병렬 경로를 가지는 multipath delay commutator (MDC) 파이프라인 구조를 채택하였다. 하드웨어 복잡도를 줄이기 위해서 새로운 스케줄링 기법들을 적용하여 twiddle factor 연산을 위한 read-only memories (ROM)의 크기를 줄이는 구조와 복소 상수 곱셈기의 수를 줄이는 구조를 제안한다. 제안하는 구조는 지연 소자와 연산 사이클의 증가 없이 하드웨어 복잡도를 줄일 수 있다. 또한, IEEE 802.11 ac/ad와 같은 고속 OFDM 시스템을 위해 64/128/256/512-포인트 FFT 연산이 가능하다. 제안하는 FFT 프로세서는 Verilog-HDL로 모델링하여 Samsung 65nm 공정 라이브러리로 합성하여 0.36mm2의 면적과 330MHz의 동작 주파수에서 2.64 GSample/s를 보이고 있다.

• Journal of Korean Neurosurgical Society
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• 제37권2호
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• pp.89-95
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• 2005

Objective: The biomechanical stabilities between the anterior plate fixation after anterior discectomy and fusion (ACDFP) and the posterior transpedicular fixation after ACDF(ACDFTP) have not been compared using human cadaver in bilateral cervical facet dislocation. The purpose of this study is to compare the stability of ACDFP, a posterior wiring procedure after ACDFP(ACDFPW), and ACDFTP for treatment of bilateral cervical facet dislocation. Methods: Ten human spines (C3-T1) were tested in the following sequence: the intact state, after ACDFP(Group 1), ACDFPW(Group 2), and ACDFTP(Group 3). Intervertebral motions were measured by a video-based motion capture system. The range of motion(ROM) and neutral zone(NZ) were compared for each loading mode to a maximum of 2.0Nm. Results: ROMs for Group 1 were below that of the intact spine in all loading modes, with statistical significance in flexion and extension, but NZs were decreased in flexion and extension and slightly increased in bending and axial rotation without significances. Group 2 produced additional stability in axial rotation of ROM and in flexion of NZ than Group 1 with significance. Group 3 provided better stability than Group 1 in bending and axial rotation, and better stability than Group 2 in bending of both ROM and NZ. There was no significant difference in extension modes for the three Groups. Conclusion: ACDFTP(Group 3) demonstrates the most effective stabilization followed by ACDFPW(Group 2), and ACDFP(Group 1). ACDFP provides sufficient strength in most loading modes, ACDFP can provide an effective stabilization for bilateral cervical facet dislocation with a brace.

• Journal of Korean Neurosurgical Society
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• 제46권4호
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• pp.285-291
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• 2009

Objective : This study examined the change of range of motion (ROM) at the segments within the dynamic posterior stabilization, segments above and below the system, the clinical course and analyzed the factors influencing them. Methods : This study included a consecutive 27 patients who underwent one-level to three-level dynamic stabilization with Bioflex system at our institute. All of these patients with degenerative disc disease underwent decompressive laminectomy with/without discectomy and dynamic stabilization with Bioflex system at the laminectomy level without fusion. Visual analogue scale (VAS) scores for back and leg pain, whole lumbar lordosis (from L1 to S1), ROMs from preoperative, immediate postoperative, 1.5, 3, 6, 12 months at whole lumbar (from L1 to S1), each instrumented levels, and one segment above and below this instrumentation were evaluated. Results : VAS scores for leg and back pain decreased significantly throughout the whole study period. Whole lumbar lordosis remained within preoperative range, ROM of whole lumbar and instrumented levels showed a significant decrease. ROM of one level upper and lower to the instrumentation increased, but statistically invalid. There were also 5 cases of complications related with the fixation system. Conclusion : Bioflex posterior dynamic stabilization system supports operation-induced unstable, destroyed segments and assists in physiological motion and stabilization at the instrumented level, decrease back and leg pain, maintain preoperative lumbar lordotic angle and reduce ROM of whole lumbar and instrumented segments. Prevention of adjacent segment degeneration and complication rates are something to be reconsidered through longer follow up period.

• Ocean and Polar Research
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• 제30권2호
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• pp.129-140
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• 2008

As a preliminary effort to establish a data assimilative ocean forecasting system, we reviewed the theory of the Ensemble Kamlan Filter (EnKF) and developed practical techniques to apply the EnKF algorithm in a real ocean circulation modeling system. To verify the performance of the developed EnKF algorithm, a wind-driven double gyre was established in a rectangular ocean using the Regional Ocean Modeling System (ROMS) and the EnKF algorithm was implemented. In the ideal ocean, sea surface temperature and sea surface height were assimilated. The results showed that the multivariate background error covariance is useful in the EnKF system. We also tested the sensitivity of the EnKF algorithm to the localization and inflation of the background error covariance and the number of ensemble members. In the sensitivity tests, the ensemble spread as well as the root-mean square (RMS) error of the ensemble mean was assessed. The EnKF produces the optimal solution as the ensemble spread approaches the RMS error of the ensemble mean because the ensembles are well distributed so that they may include the true state. The localization and inflation of the background error covariance increased the ensemble spread while building up well-distributed ensembles. Without the localization of the background error covariance, the ensemble spread tended to decrease continuously over time. In addition, the ensemble spread is proportional to the number of ensemble members. However, it is difficult to increase the ensemble members because of the computational cost.

• 대한기계학회논문집A
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• 제35권10호
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• pp.1211-1222
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• 2011

일반적으로 회전체나 초기 하중 하의 구조물 또는 열변형된 파이프 등의 프리스트레스 구조물은 이러한 프리스트레스 효과로 인하여 고유진동수 및 고유진동모드가 변화되기 때문에 정확한 고유진동해석을 위해서는 프리스트레스 고유진동해석을 수행해야 한다. 시스템에 따라서는 그 복잡성으로 인하여 수십만~수백만의 큰 자유도를 갖는 대형 유한요소모델이 요구되어 이러한 대형 모델의 프리스트레스 영향을 파악하기 위한 프리스트레스 고유진동해석을 주어진 설계시간 내에 반복적으로 수행하기에는 여전히 시간적 어려움이 많은 형편이다. 따라서, 본 논문에서는 크리로프 부공간에 근거한 축소기법으로 시스템의 초기 유한요소모델에 대하여 고유진동 특성을 정확하게 나타내면서도 작은 차수의 축소모델로 표현하여 프리스트레스 고유진동해석에서의 계산시간 문제를 감소하였다. 초기 시스템과 축소 시스템의 모멘트를 일치하는 수치계산에는 아놀디 과정을 이용하였다. 적용예제로 휠과 컴프레서 임펠러를 선택하여 제안한 방법을 통한 회전에 따른 프리스트레스 고유진동해석의 정확성과 효율성을 보였다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2011년도 제40회 동계학술대회 초록집
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• pp.20-20
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• 2011

It has been known that, under certain conditions, application of low-temperature atmospheric-pressure plasmas can enhance proliferation of cells. In this study, conditions for optimal cell proliferation were examined for various cells relevant for orthopaedic applications. Plasmas used in our experiments were generated by dielectric barrier discharge (DBD) with a helium flow (of approximately 3 litter/min) into ambient air at atmospheric pressure by a 10 kV~20 kHz power supply. Such plasmas were directly applied to a medium, in which cells of interest were cultured. The cells examined in this study were human synoviocytes, rat mesenchymal stem cells derived from bone marrow or adipose tissue, a mouse osteoblastic cell line (MC3T3-E1), a mouse embryonic mesenchymal cell line (C3H-10T1/2), human osteosarcoma cells (HOS), a mouse myoblast cell line (C2C12), and rat Schwann cells. Since cell proliferation can be enhanced even if the cells are not directly exposed to plasmas but cultured in a medium that is pre-treated by plasma application, it is surmised that long-life free radicals generated in the medium by plasma application stimulate cell proliferation if their densities are appropriate. The level of free radical generation in the medium was examined by dROMs tests and correlation between cell proliferation and oxidative stress was observed. Other applications of plasma medicine in orthopaedics, such as plasma modification of artificial bones and wound healing effects by direct plasma application for mouse models, will be also discussed. The work has been done in collaboration with Prof. H. Yoshikawa and his group members at the School of Medicine, Osaka University.

• Clinics in Shoulder and Elbow
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• 제20권1호
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• pp.3-9
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• 2017

Background: Many hyaluronic acid (HA)-based anti-adhesive agents have been commercialized for clinical use in the pharmaceutical market. But their efficacy in arthroscopic rotator cuff repairs remains elusive. To determine their efficacy, we performed a comparative analysis of the effects of two hyaluronate/carboxymethylcellulose (CMC)-based anti-adhesive agents, Protescal and Guardix. Methods: We recruited a total of 256 patients who had received an arthroscopic rotator cuff repair at our hospital between January 2014 and March 2015. Among them, 96 patients fulfilled the study's selection criteria and were enrolled as the final population sample. Thirty patients who had received a postoperative injection of Protescal were allocated into Group A. Another 30 patients who had received a postoperative injection of Guardix were allocated into Group B. As controls, 36 patients who did not receive any injection were allocated into Group C. The patients included in this study were aged between 19 and 75 years. For the clinical assessment, we measured the following clinical parameters-the visual analogue scale for pain (PVAS), the American Shoulder and Elbow Surgeons (ASES) score, and the constant score, as well as passive range of motions (ROMs)-at three time-points (preoperatively, 2-month postoperatively, and 6-month postoperatively). Results: We found that Group A compared to Group B tended to show a swifter recovery in passive anterior elevation and in internal rotation by the 2-month postoperative follow-up, but the differences were not statistically significant. Conclusions: We found that the effects of HA/CMC-based injections were minimal after arthroscopic rotator cuff repairs.