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Prevalence of Latent Tuberculosis Infection among Medical Students in South Korea

  • Jung, Da Ho;Jo, Kyung-Wook;Shim, Tae Sun
    • Tuberculosis and Respiratory Diseases
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    • v.73 no.4
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    • pp.219-223
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    • 2012
  • Background: We investigated the prevalence of latent tuberculosis infection (LTBI) among medical students in South Korea. Methods: Students from one medical school, who were in second- or third-year classes before clerkship course, were enrolled for three consecutive years in the study. A standard questionnaire was given to each participant, and tuberculin skin test (TST), QuantiFERON-TB GOLD In-Tube (QFT-GIT) assay, and chest radiography were performed. Results: A total of 153 participants were enrolled in the study. The mean age of the subjects was $21.9{\pm}0.9$ years, 105 (68.6%) were male, and 132 (86.3%) had been vaccinated with Bacille Calmette-Gu$\acute{e}$rin (BCG). Four students (2.6%) had a history of contact with tuberculosis (TB) patients during medical practice. No abnormal chest radiograph findings were found for any of the subjects. Of the 153 subjects, 23 (15.0%) tested positive for the TST, and 8 (5.2%) tested positive for the QFT-GIT. The agreement between the two tests was determined to be 0.34 using kappa coefficients. Of the four students who had a history of contact with TB patients, only one subject tested positive for both tests, and the other three students tested negative for both tests. Conclusion: A low prevalence of LTBI was found among medical students before clerkship course in South Korea.

Social and Economic Effects of Forest Management Certification: a Case of Jeju Experimental Forest (산림경영인증의 사회·경제적 효과 분석: 제주시험림의 사례)

  • Lee, Seong Youn;Lee, Ho Sang;Chung, Young Gyo;Joo, Rin Won
    • Journal of Forest and Environmental Science
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    • v.28 no.4
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    • pp.254-262
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    • 2012
  • The purposes of the research in related to FSC in JuJe experimental forests (JJEFs) is to make pre and post socio-economic comparisons and play an important role of FSC, and recognition change to FSC timbers and to make an analysis to consumers' needs. As the results of onsite survey in 2005, respondents show a high awareness of SFM and FSC in comparisons of 2004, and the JJEFs play a critical role to make SFM and FSC advertisement worldwide, such as consumers' satisfaction to SFM and FSC is high. Hence provision of JJEF information such as job creation and socio-economic impacts to stockholders could make their satisfaction improving. Most of respondents to the FSC of JJEF represent a positive rate while low awareness to FSC timber is represented. Therefore, necessary information about JJEF FSC with forest management, process and consumption pattern of FSC is required into citizens. The final results prove that FSC effects such as 1.3 billion won direct additional benefits in terms of socio-economic aspects including environmental benefits and job creation and economic effects are enough to offset 1.3 billion won additional costs.

Design of Wavelength-free 1×N Optical Splitter using a Tapered Waveguide (Compact, Fiber Array-free 광패키징 구현을 위한 신개념 광소자 설계)

  • Bae, Han Uk;Shim, Young Bo;Park, Jun Tae;Lee, Chang rin;Jeong, Myung Yung
    • Journal of the Microelectronics and Packaging Society
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    • v.24 no.4
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    • pp.19-22
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    • 2017
  • In this study, wavelength-free $1{\times}N$ optical splitter using a tapered polymer waveguide was studied to realize the transmission network of high-speed information communication network. Based on the evaluation of mode converting characteristics of splitter having two tapered multi-mode interference structures, an optimized structure of the $1{\times}N$ splitter was proposed for wide-range of input wavelength. 2D-BPM analysis $1{\times}8$ model showed that insertion loss of the proposed splitter is less than 10 dB for wavelength of input source from 1260 nm to 1650 nm.

Quality Characteristics of Dressing with Freeze-Dried Natto (동결건조 낫토를 첨가한 드레싱의 품질특성)

  • Kim, Kyung-hee;Kim, Ye-Rin;Kim, Su-A;Han, Tae-In;Park, Ro-Dong;Hong, Gyung-Deok;Hwang, Sang-Duk;Yong, Ju-Sun;Kim, Jae-Suk
    • Journal of the Korean Society of Food Culture
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    • v.35 no.4
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    • pp.387-391
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    • 2020
  • This study assessed the color, polyphenol content, and sensory characteristics of dressing containing varying concentrations (0, 3, 6 and 9%) of freeze-dried Natto. We determined that the absence of freeze-dried Natto (0%) imparted the highest additive value for both L and a, b. The polyphenol contents obtained were 0.63, 0.69, 0.74, and 0.82 mg/g for 0, 3, 6 and 9% of dressing containing freeze-dried Natto, respectively. The appearance, color, taste, texture, and overall preference of dressings with freeze-dried Natto showed significant differences between the samples. The overall preference was highest at 5.92 points, with dressing containing 9% Natto. The quality characteristics of the 9% added samples exhibited significantly higher values as compared to those of the controls, raising the possibility of development as a health-functional dressing.

Quality Characteristics of Nutritional Bar Supplemented with Freeze-Dried Natto (동결건조 낫토를 첨가한 영양바의 품질특성)

  • Kim, Kyung-hee;Kim, Ye-Rin;Kim, Su-A;Han, Tae-In;Park, Ro-Dong;Hong, Gyung-Deok;Hwang, Sang-Duk;Yong, Ju-Sun;Kim, Jae-Suk
    • Journal of the Korean Society of Food Culture
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    • v.35 no.4
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    • pp.382-386
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    • 2020
  • This study evaluated the color, DPPH radical activity, and sensory characteristics of nutritional bars supplemented with varying concentrations (0, 2.5, 5, and 7.5%) of freeze-dried Natto. An inconsistent pattern was observed for the L value, whereas both a and b values increased significantly up to 5% addition of freeze-dried Natto. The DPPH free radical scavenging activity of nutritional bars supplemented with 0, 2.5, 5, and 7.5% freeze-dried Natto were determined to be 59.54, 59.70, 44.85, and 55.07%, respectively. The appearance, color, taste, texture, and overall preference of nutritional bars supplemented with freeze-dried Natto showed significant differences between the samples. The overall preference of the nutrient bar was highest at 6.08 points, determined for the 2.5% Natto supplemented bar. The quality characteristics of the 2.5% added samples exhibited significantly higher values as compared to the controls, thereby indicating the potential of development in health-functional cereal bars.

Protective Effects of Sosokmyoung-tang Against Parkinson's Model in Human Neuroblastoma SH-SY5Y Cells (사람 신경모세포종 SH-SY5Y 세포주의 파킨슨 모델에 대한 소속명탕(小續命湯)의 보호효과)

  • Woo, Chan;You, Ju-Yeon;Jang, Chul-Yong;Kim, Hyo-Rin;Shin, Yong-Jeen;Moon, A-Ji;Shin, Sun-Ho
    • The Journal of Internal Korean Medicine
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    • v.35 no.3
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    • pp.298-308
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    • 2014
  • Objectives: In this study we made an effort to investigate the protective effect of SSMT on the N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) -induced cytotoxicity of SH-SY5Y cells. Methods: The cell viability was assessed by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MMT) assay. The fluorescence intensity was measured by using a dye and then with propidium iodide (PI) DNA flow cytometry analysis of the effects on the cell cycle of the SH-SY5Y cells and were used to measure the fluorescence of intracellular reactive oxygen species generation by MPTP. Results: Pretreatment of SSMT significantly suppressed MPTP-induced cytotoxicity, which was revealed as apoptosis characterized by the reduction of cell viability, the increase of ROS production, and the loss of mitochondrial membrane potential in SH-SY5Y cells. Conclusions: These findings suggest that SSMT exerts neuroprotective effects on human neuroblastoma SH-SY5Y cells by MPTP-induced dopaminergic neurodegeneration.

Preliminary Risk Assessment of Several Major Pharmaceutical Products In Aquatic Ecosystem

  • Park, Su-Jung;Oh, So-Rin;Jung, Jin-Yong;Kim, Young-Hee;Kim, Pan-Gyi;Choi, Kyung-Ho
    • Proceedings of the Korean Environmental Health Society Conference
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    • 2005.06a
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    • pp.345-350
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    • 2005
  • Acute toxicities of five pharmaceutical products were evaluated with aquatic microbes, invertebrates, and fish. The test pharmaceuticals, i.e., cimetidine, carbamazepine, diltiazem, acetaminophene, and metformin have been often detected in aquatic environment, but theire cological hazard on receptors of various trophic levels has seldom been evaluated. In the present study, we conducted acute toxicity assays with a marine bacterium, Vibrio fischeri, an invertebrate, Daphnia magna, and a fish, Japanese medake (Oryzias latipes). In general, D. magna, showed the most sensitive response to the test chemicals. Diltiazem exhibited the lowest EC50 value after 96 hr of exposure at 7.6 mg/L, followed by cimetidine >acetaminophen > metformin = carbamazepine in an order of decreasing susceptibility. With the fish, diltiazem and carbamazepine showed the 96 hr EC50 values at 14.1${\sim}$35.4 mg/L while acetaminophen, cimetidine, and metformin did not cause 50% mortality at 100 mg/L. Similar pattern was noted with the Microtox Assay, with which the median effective concentrations for acetaminophen, cimetidine, and metformin were found at the range between 301.8 and 755.4 mg/L. Carbamazepine and diltiazem exposure to the microbes resulted in EC50 values around 50 mg/L. Predicted no effect concentrations (PECs) of these pharmaceuticals derived from the EC5O values obtained from this study, and predicted environmental concentrations (PECs) obtained from available literatures were utilized to estimate ecological risks of the test compounds. No test pharmaceuticals resulted in risk quotients (PEC/PNEC) greater than 1, which suggests no serious potential ecological concerns. It should be noted however that further studies including the refinement of PEC derivation, identification and toxicity assessment of the metabolites and/or their interactions with other stressors may be warranted to better understand the environmental consequences of the residual pharmaceutical discharge to the waterway.

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Study on the Iron Production Process through the Analysis of By-Products Found at Jiǔdiàn Iron Production Site, China

  • Bae, Chae Rin;Cho, Nam Chul;Jo, Young Hoon;Chen, Jianli
    • Journal of Conservation Science
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    • v.34 no.4
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    • pp.273-281
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    • 2018
  • $Ji{\check{u}}di{\grave{a}}n$ iron production site in China is a relic smelting site, which in the past produced pig iron. In this study, scientific analysis of the smelting furnace and collected slag was conducted to reveal some aspects of the ancient Chinese smelting technique. A 3D model of the smelting furnace showed a narrow lower part and an upper section which increased in diameter upwards. Although the smelting furnace relic does not include the upper part and its complete shape cannot be predicted, the remaining part suggests that the furnace had a larger diameter in the central part compared to the upper and lower parts. Most of the collected slag was completely vitrified. Long prismatic fayalite was observed in the matrix of some samples. The iron particles contained phosphorus, which could not be discharged during smelting work. In addition, as the $CaO/SiO_2$ ratio was 0.42 or lower in the results of the content analysis, no CaO slag former had been added. However, the ratio of $CaO/SiO_2$ to $Al_2O_3/SiO_2$ did not have a constant trend. This needs to be investigated in a further study.

A Comparative Study of CG CryoDerm and AlloDerm in Direct-to-Implant Immediate Breast Reconstruction

  • Lee, Jun Ho;Park, Ki Rin;Kim, Tae Gon;Ha, Ju-Ho;Chung, Kyu-Jin;Kim, Yong-Ha;Lee, Soo Jung;Kang, Soo Hwan
    • Archives of Plastic Surgery
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    • v.40 no.4
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    • pp.374-379
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    • 2013
  • Background To date, various types of acellular dermal matrix (ADM) have been developed for clinical use. AlloDerm is the most familiar type of ADM to most surgeons in breast reconstruction. It is prepared by freeze-drying. CG CryoDerm is the first form of ADM that requires no drying process. Therefore, theoretically, it has a higher degree of preservation of the dermal structures than AlloDerm. We conducted this study to compare the clinical course and postoperative outcomes of patients who underwent direct-to-implant breast reconstructions using AlloDerm and those who did using CG CryoDerm. Methods We performed a retrospective analysis of the medical records in a consecutive series of 50 patients who underwent direct-to-implant breast reconstruction using AlloDerm (n=31) or CryoDerm (n=19). We then compared the clinical course and postoperative outcomes of the two groups based on the overall incidence of complications and the duration of drainage. Results The mean follow-up period was 16 months. There were no significant differences in the overall incidence of complications (seroma, infection, skin flap necrosis, capsular contracture, and implant loss) between the two groups. Nor was there any significant difference in the duration of drainage. Conclusions CG CryoDerm has the merits of short preparation time and easy handling during surgery. Our results indicate that CG CryoDerm might be an alternative allograft material to AlloDerm in direct-to-implant breast reconstruction.

A Study on the EMI Denoising Using the Ferrite Core for Facsimile (페라이트 코어를 이용한 팩시밀리에서의 EMI 제거에 관한 연구)

  • Yun, Ki-Bang;Yu, Rin;Kim, Ki-Doo
    • Journal of the Institute of Electronics Engineers of Korea TE
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    • v.37 no.5
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    • pp.28-35
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    • 2000
  • In this paper, we design a ring inductor using the ferrite core to denoise the EMI(Electromagnetic Interference) for facsimile. The EMI for facsimile is radiated from the signal line of PSTN(Public Switching Telephone Network) between facsimile and PSTN. We denoise the radiated noise by inserting a ferrite core(Ni-Zn) between facsimile and PSTN. Even though we may denoise the radiated noise using two or more than two ferrite cores, we only concentrate on denoising EMI by adjusting number of turns of one ferrite core since it gives economical gain. As a result of measuring EMI using the designed inductor with 4 turns inserted in the line connected between facsimile and PSTN, the value of radiated emission is reduced below 30 dB$\mu$V/m.

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