• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2009.05a
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• pp.354-358
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• 2009

Micro gas turbine engine is well known as a power plant of unmanned aerial vehicle and a small scale emergency generation system and also, it is significant as initial research of large gas turbine and educational purpose of gas turbine. Many sort of Micro gas turbine test set for education is produced by several manufacturers, but all of the engine control system of them is separated with data acquisition system; moreover, the engine control algorithms are inaccessible and related variables could not be collected. In this investigation, the Integrated Modifiable Test Rig which has modifiable engine start-up, drive and situational control logics is developed by LabVIEW with I/O devices and it provides wide experimental applicability to studies of dynamic characteristics of fuel system and combustion instability.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2010.11a
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• pp.1037-1038
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• 2010

• Microbiology and Biotechnology Letters
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• v.46 no.4
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• pp.320-325
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• 2018

Hepatitis E virus (HEV) infection accounts for 20 million annual infections worldwide. HEV can be fatal in approximately 20-30% of pregnant women. HEV infections are normally self-limiting and mostly asymptomatic. However, in patients with insufficient immunity, such as acquired immunodeficiency syndrome patients, chronic and often fatal infections may ensue. Therefore, it is likely that host immune responses, especially interferon responses, play a critical role in HEV infection control. Here, we report that an HEV-encoded non-structural protein down-regulates type I interferon response. In addition, some other immune genes involved in the induction of type I interferon may be regulated as well. Detailed molecular mechanisms are currently being studied.

• Transactions of the Korean Society of Mechanical Engineers
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• v.17 no.9
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• pp.2181-2190
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• 1993

An electro-hydraulic controlled rig type CVT(Continuously Variable Transmission) system was developed and its performance tests were carried out for the optimal operation. A CVT map was suggested based on the speed ration-axial force-torque relationship which was derived from the metal belt CVT mechanics. Also, a real time control and operation software was developed for the electro-hydraulic CVT system. By using the software and the CVT map, the control system was designed for the CVT speed ratio control with various drive modes. The electro-hydraulic CVT system developed in this study showed that the optimal operation algorithm could be obtained for the best fuel economy or the maximum power mode.

• Proceedings of the KSME Conference
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• 2004.11a
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• pp.178-183
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• 2004

For developing fatigue design curve of cast stainless steels that would be used in piping material of domestic nuclear power plants, a low-cycle fatigue test rig was built. It is capable of performing tests in pressurized high temperature water environment of PWR. Cylindrical specimens of CF8M were used for the strain-controlled environmental fatigue tests. Fatigue life was measured in terms of the number of cycles with the variation of strain amplitude at 0.04%/s strain rates. The disparity between target length and measured length of specimens was corrected by using finite element method. The corrected test results showed similar fatigue life trend with another previous results.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2004.05a
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• pp.218-221
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• 2004

This Research is to test the running stability of the developed bogie with 350km/h of which conventional speed is faster than Korea TGV 300Km/h. The running stability test has been executed in status of a car with the developed bogie on the roller rigger to adjust similar to the actual condition. And the test has been done in the two rail conditions, i.e. excitation and non-excitation, respectively. Running speed of bogie increased by the roller step by step. In consequence, the developed bogie in the non-excitation has run without any unstable point for 400kn0h. Vibration characteristics of carbody also was within the value specified on the UIC 518.

• Proceedings of the KSR Conference
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• 2002.10b
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• pp.839-844
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• 2002

This research aims to test the running stability of the developed bogie with maximum operating speed of 350km/h, which of Korea TGV was 300km/h. The running stability test has been executed in status of a dummy car with one developed bogie and one dummy bogie on the roller rig to embody similar operation condition. The test has been done in the two rail conditions, i.e. excitation and non-excitation, respectively. Running speed has been increased by the roller step by step. In consequence, the developed bogie was proven to be able to run upto 400 Km/h without any unstable point in the non-excitation. Vibration characteristics of carbody also was within the value specified on the UIC 515.

• Proceedings of the KSME Conference
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• 2007.05a
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• pp.1859-1863
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• 2007

A new type of a fretting wear tester has been designed and developed in order to simulate the actual vibration behavior of a nuclear fuel rod for springs/dimples in room temperature. When considering the actual contact condition between fuel rod and spring/dimple, if fretting wear progress due to the flow-induced vibration (FIV) under a specific normal load exerted on the fuel rod by the elastic deformation of the spring, the contacting force between the fuel rod and dimple that were located in the opposite side should be decreased. Consequently, the evaluation of developed spacer grids against fretting wear damage should be performed with the results of a cell unit experiments because the contacting force is one of the most important variables that influence to the fretting wear mechanism. Therefore, it is necessary to develop a new type of fretting test rig in order to simulate the actual contact condition. In this paper, the development procedure of a new fretting wear tester and its performance were discussed in detail.

• Transactions of the Korean Society of Automotive Engineers
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• v.5 no.4
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• pp.121-129
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• 1997

Gear train system test rig of power circulating type was fabricated, and systematic experiment for measuring dynamic characteristics of the planetary gear trains in the low speed region has been carried out using the test rig. The measured parameters are fillet strains of the sun gear and ring gear, carrier displacements, torques of the input and output shafts. The results are as follows : i) Even though the loading torque is constant, torque variation has been observed on the input and output hafts, ii) The variation of the torque has two frequency components, i.e. lower one of the input shaft rotation and higher one of the two teeth meshing, iii) The variation of the fillet strains shows the same tendency as that of the torque, iv) The loci of the carrier depend on the torque and rotational speed.

• Journal of Microbiology and Biotechnology
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• v.30 no.12
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• pp.1801-1809
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• 2020

Chikungunya virus (CHIKV) was first identified in 1952 as a causative agent of outbreaks. CHIKV is transmitted by two mosquito species, Aedes aegypti and A. albopictus. Symptoms after CHIKV infection in human are typically fever and joint pain, but can also include headache, muscle pain, joint swelling, polyarthralgia, and rash. CHIKV is an enveloped single-stranded, positive-sense RNA virus with a diameter of approximately 70 nm. The pathogenesis of CHIKV infection and the mechanism by which the virus evades the innate immune system remain poorly understood. Moreover, little is known about the roles of CHIKV-encoded genes in the viral evasion of host immune responses, especially type I interferon (IFN) responses. Therefore, in the present study, we screened CHIKV-encoded genes for their regulatory effect on the activation of nuclear factor kappa B (NF-κB), a critical transcription factor for the optimal activation of IFN-β. Among others, non-structural protein 2 (nsP2) strongly inhibited melanoma differentiation-associated protein 5 (MDA5)-mediated induction of the NF-κB pathway in a dose-dependent manner. Elucidation of the detailed mechanisms of nsP2-mediated inhibition of the MDA5/RIG-I signaling pathway is anticipated to contribute to the development of virus-specific therapeutics against CHIKV infection.