• Title/Summary/Keyword: RI Test

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Improving Archival Descriptive Standard Based on the Analysis of the Reviews by Archival Communities on RiC-CM Draft (RiC에 대한 기록공동체의 리뷰를 통해 본 기록물 기술표준 개선을 위한 제안)

  • Park, Ziyoung
    • The Korean Journal of Archival Studies
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    • no.54
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    • pp.81-109
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    • 2017
  • This study suggests an analysis of the reviews provided by international archival professionals on the RiC-CM draft published by ICA EGAD. Some implications for the Korean archival management environment were also suggested. Some professional reviews were accessible through the internet. Italian archival professionals held workshops at various levels for the analysis and discussion of the draft. Duranti, the project director of InterPARES, also gave opinions about the draft in cluding the perspective of digital preservation. In the review of Artefactual, the draft was discussed in terms of system implementation. Reed, the director of Recordkeeping Innovation, also gave a feedback based on the record management experiences in Australia. Some implications can be suggested based on these professional opinions. First, we should try to build a test bed for the adoption of RiC to archival description in the Korean environment. Second, a minimum level of data elements that can secure authenticity and integrity will also be needed. Third and lastly, rich authority data for agents and functions related to archival records and records groups are essential to take full advantage of the standard.

Analysis of Change Transitions in Regional Types in Emergency Department Patient Flows of in Jeonlado (2014-2018) (전라지역 응급실 환자의 유출입 분석 및 지역유형 변화 추이)

  • Lee, Jae-Hyeon;Lee, Sung-Min;Kim, Seongjung;Oh, Mi-Ra
    • Journal of Convergence for Information Technology
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    • v.10 no.12
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    • pp.126-131
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    • 2020
  • This study analyzed the inflow and outflow patterns of emergency department patients, to identify changes in regional types in cities, counties, and districts in Jeonlado, Korea. Data of areas in Jeonlado for 2014 to 2018 were extracted from the National Emergency Department Information System. The extracted data includes the patients' and emergency medical institution addresses, which were used to calculate the relevance index (RI) and commitment index (CI). The calculated indices were classified into regional types by applying cluster analysis. A non-parametric method, Kruskal-Wallis test, was employed to examine the differences between years for RI and CI by regional types. The results of cluster analysis using the relevance and commitment indices revealed three regional types. Regions in cluster 1 were classified as outflow type, in cluster 2 as inflow type, and in cluster 3 as self-sufficient. RI and CI were calculated for each cluster or regional type. There were no significant differences between years in cluster 2 (inflow type) and cluster 3 (self-sufficient type). In cluster 1 (outflow type), there were no significant differences in CI between the years; however, there were significant differences in RI between 2014 and 2017, and 2014 and 2018. It is difficult to see that the emergency medical environment has improved due to the increased concentration of emergency medical care.

Analysis of a Pollutant Flow Tracer Test in River using Radioactive Isotope (하천에서 추적자를 이용한 오염물질 거동분석)

  • Kim, Ki-Chul;Lee, Jong-Seok
    • The Journal of the Korea Contents Association
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    • v.9 no.1
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    • pp.400-406
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    • 2009
  • In this study, in order to find the movement of polluted substance that is flown into the river and the characteristics of dispersion, the experiment that used the RI (Radioactive Isotope) tracer in the river was undertaken, and by using the experiment result, the figure modelling was undertaken to analyze the general type of pollutant dispersion. In addition, in order to calculate more accurate dispersion range and moving time, the experiment was done in about 2km from the measuring points of Namdae Stream around the Yongdam Dam of the upper Geum River to the lower stream. In order to find out the flow of river and dispersion of polluted substance, RMA (Resource Modeling Associates)-2 and RMA-4 program are used in study. The site experiment using the RI was implemented for the experiment in the applied area and the same area, and the distance between each zone was set for 1km with the slight difference for site situation and measured the density date of one second distance through the NaI apparatus to measure the density data of one second interval. On the basis of this measured data, it is compared and analyzed with the result of figure copy of the models to make the comparison and analysis of density distribution following the change in expansion coefficient that makes great influence on expansion range and dispersion in natural rivers.

Detection of vivax malaria sporozoites naturally infected in Anopheline mosquitoes from endemic areas of northern parts of Gyeonggi-do (Province) in Korea

  • Lee, Hyeong-Woo;Shin, E-Hyun;Cho, Shin-Hyeong;Lee, Hee-Il;Kim, Chung-Lim;Lee, Wook-Gyo;Moon, Sung-Ung;Lee, Jong-Soo;Lee, Won-Ja;Kim, Tong-Soo
    • Parasites, Hosts and Diseases
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    • v.40 no.2
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    • pp.75-81
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    • 2002
  • We investigated population densities of mosquitoes infected with sporozoites in three highly epidemic areas of Josan-ri and Jangpa-ri (Paju City) and Dongjung-ri (Yeoncheon County) in Korea. Anopheline mosquitoes were collected front both indoors and outdoors by human baiting collection method during the period of the first week of June to the second week of September 1999. Total 13,296 female mosquitoes were collected and 8,650 (65.1%) were Anophelines. Thirty seven percent (3,199) of the Anopheline mosquitoes were captured outdoors and 63.9% (5,531) indoors. Employing a sandwich enzyme-linked immunosorbent assay (ELISA), we analyzed a total of 7,820 Anopheline mosquitoes and found that 7 Anopheline mosquitoes were infected with sporozoites. The positive rate in Josan-ri was 0.14% (5/3,500) and 0.15% (2/1,370) in Jangpa-ri. The total positive rate in all three surveyed areas was 0.09% (7/7,820). The mosquitoes infected with the sporozoites were detected on June $28^{th}$ (n=2), July $5^{th}$ (n=1), July $19^{th}$ (n=1), August $9^{th}$ (n=1), September $6^{th}$ (n=1), and the last one on September $13^{th}$ (n=1). They were all classified as Anopheles sinensis, which showed positive reaction in ELISA test. Therefore it might be concluded that Anopheles sinensis plays an important role in re-emerging malaria transmission in Korea.

Robust Reference Intervals for Serum Kappa and Lambda Free Light Chains from a Multi Centre Study Population from Hyderabad, India: Myeloma Diagnostic Implications

  • Mohammed, Noorjahan;Chandran, Priscilla Abraham;Kandregula, Madhavi;Mattaparthi, Ratna Deepika;Gundeti, Sadasivudu;Volturi, Jyotsna;Darapuneni, Radhika;Raju, Sree Bhushan;Dattatreya, Palanki Satya
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.5
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    • pp.2605-2610
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    • 2016
  • The International Myeloma Working Group considers the serum free light chain (SFLC) assay to be an adjunct to traditional tests. Apart from the FLC ratio, the absolute values of individual free light chains also are gaining importance as they appear to be more relevant in certain clinical settings. Automated assays are available for their determination. As laboratories put new test systems into use catering to different disease populations, they are required by accreditation and certification bodies to verify or establish performance specifications, including reference intervals (RIs) representative of their population. Our aim was to establish local RIs for SFLC in a multicentre representative healthy population using a robust method. There was no significant relationship between SFLC levels and age, gender and creatinine levels. The 95% RI for ${\kappa}SFLC$ was 4.81 to 33.86mg/L, for ${\lambda}$ SFLC was 5.19 to 23.67mg/L and for ${\kappa}/{\lambda}SFLC$ was 0.36 to 2.33, significantly higher than the values given by the manufacturer. The ${\kappa}/{\lambda}$ SFLC ratio at 2.23, covering 100% of the data, showed 72% sensitivity (95% CI=39.0 - 94.0), 100% specificity (95% CI=71.5 - 100.0), 100% PPV (95% CI=21.5 - 100.0), 95% NPV (95% CI=75.4 - 99.9), and 79% accuracy (95% CI=56.0 - 93.0). In the patient group, kit RI for ${\kappa}/{\lambda}$ SFLC ratio classified 45.5% (n=5) as positive vs 9.1% (n=1) positive by the study RI, while the kit RI for kappa FLC classified 90.9% (n=10) as positive vs 54.5% (n=6), indicating increased probability of false positive test results with the kit RI when applied to our patient population. Appropriate and specific reference intervals and criteria values result in fewer false-positive and false-negative results which means fewer wrong or missed diagnoses.

Isolation and Characterization of the Smallest Bacteriophage P4 Derivatives Packaged into P4-Size Head in Bacteriophage P2-P4 System

  • Kim, Kyoung-Jin;Song, Jae-Ho
    • Journal of Microbiology
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    • v.44 no.5
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    • pp.530-536
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    • 2006
  • Bacteriophage P4, a satellite phage of coliphage P2, is a very useful experimental tool for the study of viral capsid assembly and cos-cleavage. For an in vitro cos-cleavage reaction study of the P2-P4 system, new shortened and selectable markers containing P4 derivative plasm ids were designed as a substrate molecules. They were constructed by swapping the non-essential segment of P4 DNA for either the kanamycin resistance (kmr) gene or the ampicillin resistance (apr) gene. The size of the genomes of the resulting markers were 82% (P4 ash8 delRI:: kmr) and 79% (P4 ash8 delRI:: apr) of the wild type P4 genome. To determine the lower limit of genome size that could be packaged into the small P4-size bead, these shortened P4 plasmids were converted to phage particles with infection of the helper phage P2. The conversion of plasmid P4 derivatives to bacteriophage particles was verified by the heat stability test and the burst size determination experiment. CsCl buoyant equilibrium density gradient experiments confirmed not only the genome size of the viable phage form of shortened P4 derivatives, but also their packaging into the small P4-size head. P4 ash8 delRI:: apr turned out to be the smallest P4 genome that can be packaged into P4-sized head.

Optimization of the 32P-postlabeling Assay for Detecting Benzo(a)pyrene-induced DNA Adduct Formation in Zacco platypus

  • Lee, Jin Wuk;Lee, Sung Kyu
    • Journal of Environmental Health Sciences
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    • v.40 no.1
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    • pp.55-62
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    • 2014
  • Objectives: $^{32}P$-postlabeling assay is the most sensitive method of detecting DNA adduct formation. However, it is limited by a low sample throughput and use of radioisotopes (RI). In this study, we modified it to minimize these limitations and applied it to Z. platypus exposed to Benzo(a)pyrene (BaP) in order to investigate DNA adduct formation (effect biomarker for pollutants) in Z. platypus for assessing risk of waterborne BaP exposure. Methods: DNA hydrolysis was performed only with Micrococcal nuclease (MNase), RI reduction test was performed and the overlapping steps between thin layer chromatography (TLC) and radioisotope high-performance liquid chromatography (RI-HPLC) were omitted. The application of a modified method to Z. platypus exposed to BaP was performed. Results: The results revealed that the amount of RIs used can be reduced roughly 10-fold. Because the analysis time was shortened by 8.5 hours, the sample throughput per hour was increased compared with the previous method. The results of applying modified $^{32}P$-postlabeling assay to Z. platypus, DNA adduct formation in Z. platypus showed dose-dependency with the BaP concentration. Only BPDE-dGMP was detected as a DNA adduct. Conclusion: These results demonstrate that the modified $^{32}P$-postlabeling assay is a suitable method for detecting DNA adduct formation in Z. platypus exposed to waterborne BaP and will be useful in risk assessment of carcinogenic effect in aquatic environment due to BaP.

Study Radiological Defense Interrelationship Research in Career (경력에 따른 방사선방어 상관성 연구)

  • Kim, Jean Soo
    • The Korean Journal of Nuclear Medicine Technology
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    • v.16 no.2
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    • pp.135-138
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    • 2012
  • Purpose : This research the isotope of handling was to an actual act of the radiological defense which it follows in career of the clinical pathological companies in order to inquire the interrelation for a radiological defense. Materials and Methods : The tool of this research with question from 2010 October until November did electrification Chwung Cheng and the Seoul isotope thread clinical pathological company with the object person and it investigated in direct question or mail method, the data which is collected used SPSS19.0 programs and frequency and percentage and t-test, ANOVA, it used it analyzed a multiple regression analysis method. Results : The interrelationship of the radiological defense which it follows in career was visible the interrelation which considers statistically (p<0.01). But the correlation coefficient appeared lowly with 0.196. With the variable who affects in radiological defense act it appeared with worker providing by law educations and RI license acquisitions. Conclusion : There is to business progress and the radiological defense act respects a worker safety stands the unit only is the fact which is important. Consequently a possibility of saying that the radiation worker education is necessary, it executes the education which is continuous, RI license acquisitions, there is.

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Evaluation of Dynamic Ground Properties of Pohang Area Based on In-situ and Laboratory Test (현장실험 및 동적실내실험을 이용한 포항지역 동적 지반특성 평가)

  • Kim, Jongkwan;Kwak, Tae-Young;Han, Jin-Tae;Hwang, Byong-Youn;Kim, Ki-Seog
    • Journal of the Korean Geotechnical Society
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    • v.36 no.9
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    • pp.5-20
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    • 2020
  • In 2017, after the Pohang earthquake, liquefaction phenomena were firstly observed after the observation of domestic earthquake by epicenter. In this study, various in-situ tests and laboratory tests were performed to determine the dynamic properties in (1) Songlim Park, (2) Heunghae-eup, Mangcheon-ri and (3) Heungan-ri, Pohang. As a site investigation, the standard penetration test (SPT), cone penetration test (CPT), multichannel analysis of surface wave (MASW), density logging, downhole test, and electrical resistivity survey were performed. In addition, cyclic triaxial test against sampled sand from site was also conducted. Based on the result, high ground water level and loose sand layer in shallow depth were observed for all sites. In addition, liquefaction resistance ratio of soil sampled from Songlim park was lower than those of Jumunjin sand, Toyoura sand, and Ottawa sand.