• Journal of Radiation Industry
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• v.7 no.2_3
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• pp.209-219
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• 2013

RI-Biomics field comes into the limelight as a new fusion radiation technology. These rapid development of RI-Biomics cause the necessity of establishment of a new methodical education program model for consistent training of professional manpower in RI-ADME, Biomics field. But domestic current status is not satisfied to training human resource development in RI-Biomics. Actually domestic educational organization related to RI-Biomics just run educational programs oriented basic theory, so practical and fusion education are not existed nowadays for preliminary RI-Biomics expert. Therefore we established a new education program model for educate of the expert in RI-Biomics field to overcome current problem about the route of knowledge that has more monotonous and concentrated tendency and non-professional education. To improve universality and practicality, we conduct education-training model survey about domestic and foreign country. This new human resource development model will contribute to fostering new expert in RI-Biomics field.

• Journal of Radiation Industry
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• v.11 no.1
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• pp.7-11
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• 2017

RI-Biomics is a fusion technology in radiation fields for evaluating in-vivo dynamics such as absorption, distribution, metabolism and excretion (RI-ADME) of new drugs and materials using radioisotopes and quantitative evaluation of their efficacy. RI-Biomics information is being provided by RIBio-Info developed as information system for distributing its information and three requirements for improving RIBio-Info system have been derived through reviewing recent big data trends in this study. Three requirements are defined as resource, technology and manpower, and some reviews for applying big data in RIBio-In system are suggested. Fist, applicable external big data have to be obtained, second, some infrastructures for realizing applying big data to be expanded, and finally, data scientists able to analyze large scale of information to be trained. Therefore, an original technology driven to analyze for atypical and large scale of data can be created and this stated technology can contribute to obtain a basis to create a new value in RI-Biomics field.

• Journal of Radiation Industry
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• v.8 no.3
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• pp.161-168
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• 2014

Increasing utilization of radiation and RI (Radioisotope) in nuclear industry including non-power area has achieved sustainable development of radiation industry. Industries are no longer confined by a single technology or abilities but expanded for application gradually. RI-Biomics fields are one of the convergence technology that is recognized on a high-tech industry. Unlike the conventional industry, RI-Biomics field needs to various specialists to perform related task. There is no domestic training program to educate the whole process. This study aims to suggest the plan for improvement of practical skills for specialists in RI-Biomics through development of our training program. For this purpose, we have first investigated the opinion about classification scheme from experts and then analyzed the results in order to reflecting our training program. Based on analyzed results, conformity assessment was executed to organize curriculum through status of constructed device and instructor in domestic. Our training program was performed jointly with KAERI (Korea Atomic Energy Research Institute). RI-Biomics center is prepared with facilities of overall experiment to improve quality of education. Due to the fact that specialists have routine task, we organized a five-day short course to reflect temporal difficulties. We performed a trial operation to 6 participants in RI-Biomics field. Through the survey for the specialists who participated in the program, we evaluated the efficiency of our training program. The results showed that participants were satisfied with the organized curriculum and educational materials. Therefore, our program is expected to be utilized as basic research data to develop feasible program for policy development and to improve practical skills in RI-Biomics.

• Journal of Radiation Industry
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• v.11 no.1
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• pp.33-38
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• 2017

RI-Biomics technology is advanced convergence technologies that can be measured in real time and track in vivo behavior and metabolism of substances using characteristics of the radioactive isotope. Its application fields are increasing such as drug development, agriculture, development of new materials and their utilization, etc. In addition, according to domestic and international developments and changes in the RI-Biomics environment, RI-Biomics professionals are needed to train continuously. To develop systematic human resources basement and competency-based curriculum, we perform competency modeling of pedagogical perspective to targeted at high-performance on RI-Biomics. Furthermore, we redefine the competency model and verified by industry experts with focus group interviews. In the result, two general competencies and three professional competencies were extracted by interview. Each competencies are organized six sub-competencies and nine sub-competencies. In the finial steps, the same procedures were repeated to obtain the consensus of experts on derived competencies and behavioral objectives. The results of the study are applicable to enhance human resource management and to develop the curriculum for RI-Biomics expert training. It is expected to be used as reference material of long term-planning for RI-Biomics professional.

• Journal of Radiation Industry
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• v.8 no.3
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• pp.155-159
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• 2014

RI-Biomics is a new concept that combines radioisotopes (RI) and Biomics. For efficient collection of information, establishment of database for technical information system and its application to the system, there is an increasing need for constructing the standard classification system of technical information by its systematical classification. In this paper, we have summarized the development process of the standard classification system of technical information in the field of RI-Biomics and its application to the system. Constructing the draft version for the standard classification system of technical information was based on that standard classification one in national science and technology in Korea. The final classification system was then derived through the reconstruction and the feedback process based on the consultation from the 7 experts. These results were applied to the database of technical information system after transforming as standard code. Thus, the standard classification system were composed of 5 large classifications and 20 small classifications, and those classification are expected to establish the foundation of information system by achieving the circular structure of collection-analysis-application of information.

• Journal of Radiation Industry
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• v.9 no.3
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• pp.161-166
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• 2015

RI-Biomics is the new radiation fusion technology of which, such as the characteristics of radioisotope, is applied to the biomics. In order to sharing and overall analysis of data between the institutions through total management of information in the field of RI-Biomics, RI-Biomics Information portal 'RIBio-Info' was constructed by KARA (Korean Association for Radiation Application) in February 2015. For systematic operation of this 'RIBio-Info' system, it is required to develop system of collection-analysis-application of information. So, in this paper, we summarized development of document forms at each processes of collection-analysis-application of information and systematization of collection methods of information, establishment of characteristically analysis methods of reports such as issue paper, policy report, global market report and watch report. Therefore, these are expected to improving the practical applicability in this field through the vitalization of technology development of users by achieving the circular structure of collectionanalysis-application of information.

• Proceedings of the Korean Nuclear Society Conference
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• 1997.05b
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• pp.365-372
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• 1997

이 연구의 목적은 밀도측정 및 수분함량측정용 RI 계기의 개발에 있다. 방사성동위원소를 이용하여 성토시공의 현장다짐 밀도 및 수분함량 측정에 이용되곤 있는 RI 계기는 중성자 검출부분, 감마선 검출부분, 고전압 공급부분, 마이크로 컴퓨터 부분으로 크게 나눌 수 있다. 감마선을 검출하는 G-M 검출기는 그 특징으로 인해 방사선검출 전기회로가 간단하다. 그러나 열중성자를 검출하는 He-3 검출기는 검출기에서 발생하는 신호원이 매우 작아서 검출회로의 상호 간섭으로 인한 전기적 잡음이 발생한다 이 잡음을 제거하는 것이 He-3 중성자 검출기로 열중성자를 검출하는데 중요한 문제이다. 본 연구에서 제작하는 RI 계기는 원자력법에서 제한하는 방사능 이하를 (100$\mu$Ci 의 밀봉선원) 사용하므로 종래의 RI 계기에 비해 방사선의 검출수가 줄어든다. 이에 따라 검출기의 개수를 늘려서 방사선을 검출해야 한다. 또한 본 연구에서는 He-3검출기의 검출 스펙트럼을 분석하여 적정한 방사선 검출 측정영역을 결정하였다.

• Journal of Radiation Industry
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• v.8 no.3
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• pp.169-176
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• 2014

For designing the model of the web program, the demand survey for the technology and information has been performed for the students of the related departments, industrialists and researchers. And, the survey, such as advantages and disadvantages, for the current situations has been examined through comparison and analysis by the establishment type and operational process for the present operating web programs having the similar functions in Korea. The contents and web program for the technology and information system have been also developed by the question investigation and the expert opinions. This system for RI-Biomics has been developed by focusing the convenience for the information provision and the information search as the first constructing direction. Information has been collected by the operator in our institute and making contract with Global Trend Briefing of KISTI in Korea. The information collection in the web program has been designed as the direction regularly provided with RSS. Information has been then analyzed by constructing the expert pool provided from the advisory committee for the technology and information, and using them. The publicity for this web program has been performed by webzines and then it is noted that the publicity programs such as some events should be regularly developed when expanded and advanced to a community in future.

• Nuclear industry
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• v.5 no.7 s.29
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• pp.18-21
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• 1985

1930년이래 원자로나 입자가속기를 이용하여 여러 종류의 방사성동위원소(Radioisotope, RI)를 인공적으로 생산하게 됨에 따라 1960년대부터는 인공 RI를 여러 분야에서 이용하게 되었고, 우리나라에서도 상당량의 RI 및 그 표식화합물들을 생산 또는 수입하여 이용함으로써 우리 생활과 밀접한 관계를 갖게 되었다. 더구나 천연자원이 부족한 우리나라는 원자력발전을 통하여 그 돌파구를 찾지 않을 수 없게 됨에 따라 원자력은 우리 앞에 성큼 다가왔고 여러가지 RI 및 방사선에 대한 관심도 높아졌다. 즉, 우리는 이제 원자력시대에 살고 있어 이와 관련한 기본지식을 외면하는 것은 곧 현실을 외면하는 것이 되었다. 최첨단 거대과학, 그 한쪽 분야를 살펴 보기로 하자.

• Journal of Radiation Industry
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• v.3 no.1
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• pp.25-29
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• 2009

Microarrays can be used to screen thousands of binding events in a parallel and high throughput fashion and are of major importance in disease diagnosis and drug discovery. The use of radioisotope is conventionally regarded as one of the most sensitive detection methods. Atherosclerosis is a common disorder affecting arterial blood vessels. It happens when fat, cholesterol, and other substances made in the arterial blood vessels form a hard substances called plaque. Lipoprotein-associated phospholipase $A_2$ ($Lp-PLA_2$), a phospholipase $A_2$ enzyme, is used as a marker for cardiac disease. The detection of $Lp-PLA_2$ was accomplished by using radioactive [$^3H-acetyl$] PAF as a substrate and a feasibility study on RI biochip application to detection of $Lp-PLA_2$, a risk factors of atherosclerosis was performed. Inhibitive activity of a native plant extract was also determined by using the RI biochip. It was found to be applicable to a high-throughput screening of inhibitors for developing atherosclerosis therapeutic agents.