• 보건행정학회지
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• 제23권1호
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• pp.52-58
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• 2013

This study was conducted to investigate the responsiveness and its related factors of public health center for novel influenza A (H1N1) epidemic. The data was collected through a web-based survey conducted during February to April 2011. The 182 respondents were team leaders or persons who were responsible for H1N1-related work at public health centers during the H1N1 prevalence. The related factors affecting the responsiveness were different by urban or rural area. In the level of gu (urban) area, cooperation with the public organizations, preparing its own response plan were the significant factors. But, in the level of si or gun (rural) area, cooperation with private organizations (clinic or pharmacy), physical (facilities, equipments, and medicines), and human infrastructures (public health professions, education and knowledge, and motivation) were more important factors. Therefore, how to cope with H1N1 prevalence in the future should be different by local characteristics. As a result, there are several challenges that public health centers should prepare for the further emerging infectious diseases. First, it is needed to make standard manuals which could strengthen education and training in order to respond appropriately, as well as to prepare enough physical infrastructures for the crisis. Next, the public health center should prepare correct media response and cooperation system with public and private organizations.

• The Korean Journal of Pain
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• 제11권1호
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• pp.23-29
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• 1998

Background: The present study was conducted to investigate effects of microinjection of bicuculline, GABA-A receptor antagonist, into the brain stem nuclei on the dorsal horn neuron responsiveness in rats with an experimental peripheral neuropathy. Methods: An experimental neuropathy was induced by a unilateral ligation of L5~L6 spinal nerves of rats. After 2~3 weeks after the surgery, single-unit recording was made from wide dynamic range (WDR) neurons in the spinal cord dorsal horn. Results: Responses of WDR neurons to both noxious and innocuous mechanical stimuli applied to the somatic receptive fields were enhanced on the nerve injured side. These enhanced responsiveness of WDR neurons were suppressed by microinjection of bicuculline into periaqueductal gray(PAG) or nucleus reticularis gigantocellularis(Gi). A similar suppression was also observed when morphine was microinjected into PAG or Gi. Suppressive action by Gi-bicuculline was reversed by naloxonazine, ${\mu}$-opioid receptor antagonist, microinjected into PAG whereas PAG-bicuculline induced suppression was not affected by naloxonazine injection into Gi. Gi-bicuculline induced suppression were reversed by a transection of dorsolateral funiculus(DLF) of the spinal cord. Conclusions: The results suggest that endogenous opioids, via acting on GABAergic interneurons in PAG and Gi, may be involved in the control of neuropathic pain by activating the descending inhibitory pathways that project to the spinal dorsal horn through DLF to inhibit the responsiveness of WDR neurons.

• 한국응급구조학회지
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• 제8권1호
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• pp.33-45
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• 2004

The study is designed to develop an educational CD-Title for Basic Life Support. The study is conducted from July to December, 2002, Based on the course of program development suggested by Dick and Cray. the study followed the planning, development, education and evaluation of a program. The developed CD-Title consists of 8 parts. 1. Intro include Introduction, Adult CPR, Child CPR, Infant CPR, Adult Foreign-Body Airway Obstruction, Infant Foreign-Body Airway Obstruction, and Exercise in Menu at Right of screen. 2. Introduction consist of death process at cardiac arresst, chain of survival, introduction of CPR, respiratory & ciculatory anatomy and physiology. 3. Adult CPR consist of assessment responsiveness, activating EMS system, position victim, opening a airway, checking for breathing, rescue breathing, checking for sign of circulation, chest compression, 1 person & 2 persion adult CPR video. 4. Child & Infant CPR consist of, causes, assessment responsiveness, position victim, opening the airway, checking for breathing, rescue breathing, checking for sign of circulation, chest compression, activating EMS system, child & infant CPR video. 5. Adult Foreign-Body Airway Obstruction include assessment responsiveness, activating EMS system, position victim, opening a airway, checking for breathing, 2 rescue breathing, reopening the airway, 2 rescue breathing, finger sweep, 5 abdominal thrusts, unresponsiveness adult Foreign-Body Airway Obstruction video. 6. Infant Foreign-Body Airway Obstruction consist of, causes, assessment responsiveness, position victim, opening the airway, checking for breathing, 2 rescue breathing, reopening the airway, 2 rescue breathing, checking foreign-body object in oral cavity of victim, 5 back blow, 5 chest thsusts, activating EMS system, video. 7. 32 exercise consist of 8 Adult CPR, 12 Child & Infant CPR, 5 Adult Foreign-Body Airway Obstruction, 7 Infant Foreign-Body Airway Obstruction. Every part consist of animations to trigger students interests. This CD-Title will be useful education for first responders and lay rescuers.

• 한국작물학회지
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• 제42권5호
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• pp.548-555
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• 1997

1. 낮은 농도의 지베렐린 처리에서는 돌연변이종의 절간장이 야생종보다 훨씬 많이 신장되어 지베렐린에 의한 절간 신장현상은 파이토크롬 B를 통하여 이루어짐을 보였다. 2. 고농도의 GA처리시 이들간의 초장 및 절간장의 차이는 나타나지 않아 고농도의 지베렐린에 의한 절간신장효과는 파이토크롬 B에 의존하지 않았다. 3. GA$_3$ 처리 후 내생 지베렐린의 함량을 조사한 결과 파이토크롬 B 변이종과 야생종간에는 큰 차이를 보이지 않음에도 불구하고 절간 신장률은 변이종이 야생종보다 현저하여 파이토크롬 B가 지베렐린의 반응 정도를 조절함을 입증하였다. 4. GA 생합성 억제제에 의한 내생 지베렐린의 합성이 억제된 경우 파이토크롬 B 변이종과 야생종간의 절간신장은 차이를 보이지 않아 파이토크롬의 절간신장효과는 지베렐린을 통해 일어남을 알 수 있었다.

• 한국융합학회논문지
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• 제11권5호
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• pp.281-288
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• 2020

본 연구의 목적은 유아의 스마트기기 몰입경향성에 미치는 어머니 스마트기기 과의존의 영향과 반응성의 매개효과를 단기종단적으로 검증하는 데 있었다. 이를 위하여 3-5세 유아-어머니 144쌍(남아 73명, 여아 71명)을 대상으로 시점 1에서 어머니의 스마트기기 과의존과 유아의 스마트기기 몰입경향성, 6개월 후인 시점 2에서 유아의 몰입경향성과 모-아 상호작용 동안 양육자 반응성을 측정하였다. 이때 스마트기기에 대한 어머니의 과의존과 유아의 몰입경향성은 어머니 보고를 통해, 양육자 반응성은 모-아 상호작용 녹화 자료에 대한 관찰자 코딩을 통해 수집하였다. 경로분석을 통해 분석한 결과, 시점 1에서의 유아의 몰입경향성을 통제했을 때, 시점 1에서의 어머니의 과의존 경향성은 시점 2에서의 양육자 반응성을 매개로 시점 2의 유아의 스마트기기 몰입경향성을 간접적으로 유의하게 예측하였을 뿐만 아니라 직접적으로 예측하였다. 본 연구의 의의는 양육자의 스마트기기 사용 특성이 유아의 스마트기기 몰입경향성에 미치는 영향을 종단적 측면에서 실증적으로 살펴보았다는 점에서 찾을 수 있다.

• 한국산림과학회지
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• 제90권1호
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• pp.139-145
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• 2001

솔껍질깍지벌레 수컷의 고치탈출후의 행동습성, 그리고 합성페로몬에 대한 수컷의 반응에 관여하는 기상적 요인에 관한 시험결과는 다음과 같다. 해송치수에 고치탈출 직후의 수컷과 갓 탈피한 암컷성충을 올려 놓았을 때 수컷은 기어다니며 암컷을 찾아 1회내지 수회 교미후 이륙하였다. 암컷이 없는 경우 수컷은 5분 이내에 모두 이륙하였으나, 근처에 암컷이 있는데 인위적으로 교미를 못하게 한 경우는 2시간이 넘도록 수컷이 이륙하지 않았다. Wind tunnel에서의 시험에 있어 합성페로몬의 존재는 수컷의 이륙을 억제하는 효과를 나타냈다. 비행중의 수컷은 그늘보다는 양지에서 더 많은 개체가 자유비행을 하지만 광량은 페로몬에의 감응정도에는 영향을 미치지 않았고 풍속이 페로몬의 감응에 영향을 미치는 주요인이었다. 대부분의 수컷은 다양한 자세로 페로몬 발산체와 가까운 물체에 부딪친후 바로 일어나 페로몬 발산체로 걸어서 접근하였다.

• 한국의류학회지
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• 제44권4호
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• pp.639-656
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• 2020

Consumers' shopping experience has recently expanded to mobile and social networks; in addition, online fashion retailers started to focus on real-time interaction services as an emerging marketing tool. This study explores the consumer' shopping experience based on social live streaming services (SLSS) to investigate consumer's response behavior and effects through perceived service quality. An online survey method was conducted and a total of 186 female consumer panels were collected. The results indicate that cognitive communion of co-experience had a significant effect on perceived SLSS service quality (responsiveness, contents informativeness, playfulness, system availability). Service quality of SLSS (responsiveness, contents informativeness, and playfulness) had significant effect on trust in SLSS seller while system availability had no significant effect. Also, trust in seller showed significant effect on purchase intention. Last, it was confirmed that the moderating effect of purchasing experience of SLSS was significant in the relationship between cognitive communion and responsiveness/playfulness. There was also an additional significant moderating effect of purchasing experience between system availability and trust in seller.

• 로봇학회논문지
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• 제12권3호
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• pp.365-375
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• 2017

The purpose of this study was to investigate cognition of life phenomenon on robotic dogs according to properties of robotic dogs amongst aged 3, 4 and 5. 95 Children aged 3 to 5 years participated in this study. Each child was interviewed individually and responded to questions designed to measure his/her cognition of life phenomenon. The major findings of this study are as follows. First, there was a significant difference in children's cognition of the life phenomenon according to their age. 3 years were more likely to refer the robotic dog as alive, compared to the 5 years. Secondly there was a significant difference in children's inference of the life phenomenon according to properties of robotic dogs. Such as high activeness and responsiveness, preschoolers considered robotic dogs to be alive and have more biological and psychological traits. This result shows the activeness and responsiveness of robotic dogs influences young children's inference of life phenomenon.

• 유통과학연구
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• 제15권2호
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• pp.37-46
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• 2017

Purpose - This research investigates whether e-service quality has the influence on long-term orientation, consumer commitment, and satisfaction. Research design, data, and methodology - Data collection took place for 30 days from October 1, 2015 to October 31, 2015. 315 copies had been analyzed. Covariance structure analysis with credibility and factor analysis was conducted to verify this research hypotheses. Results - First, the lower dimension concepts of e-service quality, reliability, and tangibility had a significant influence on customer commitment, and responsiveness had a significant negative influence. However, aesthetics did not have a significant influence on that. Secondly, aesthetics had a significant influence on long-term orientation, but reliability, tangibility, and responsiveness did not have a significant influence. Thirdly, reliability, tangibility, and aesthetics had a positive influence on customer satisfaction. However, responsiveness had a negative influence. Fourthly, customer commitment had a significant and positive influence on customer satisfaction, but customer commitment and customer satisfaction had a negative influence on long-term orientation. Conclusions - This research verifies the influencing relationship between e-service quality of a franchise coffee shop application with customer commitment, customer satisfaction, and long term orientation. By the results of this research, possibility of application and expansion of theory has been proven.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2003년도 Annual Meeting of KSAP : International Symposium on Pharmaceutical and Biomedical Sciences on Obesity
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• pp.70-70
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• 2003

Estrogen receptor is a ligand-activated transcription factor. Its action depends on the receptor, its ligand, and its coactivator proteins. As a consequence, the concentration of the receptor is a major component that governs the magnitude of the estrogen response. Despite the extensive knowledge on mechanism of estrogen receptor action, regulation of estrogen receptor itself is not very well understood. Estrogen receptor is known to be downregulated under hypoxia leading to inhibition of estrogen receptor mediated transcription activation. We have studied mechanism of loss of estrogen responsiveness under hypoxia. We found that Hif-l${\alpha}$, a major transcription factor regulating hypoxic response, inhibited transcription of estrogen response element driven luciferase gene by expression of HIF-l${\alpha}$/vp16 construct designed to contain transcription activity under normoxia. This loss of estrogen responsiveness appears to be the result of ER${\alpha}$ downregulation. ER${\alpha}$was downregulated at the levels of ligand-biding and protein within l2-24h, and the response was blocked by the proteasome inhibitor MG132, protein synthesis inhibitor cyclohexamide, and tyrosine kinase inhibitor Genistein. These results demonstrate that Hif-l${\alpha}$ downregulates ER${\alpha}$ by proteasome dependent pathway.