• Title/Summary/Keyword: RESPONSIVENESS

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Application of Molecular Diagnostics Technology in the Development of a Companion Diagnostics for Malignant Solid Tumors (악성 고형암의 항암제 동반진단 기술에서 분자진단기술의 적용)

  • Kim, Jin-Hee
    • The Journal of the Korea Contents Association
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    • v.19 no.3
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    • pp.365-374
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    • 2019
  • Unlike benign tumors, malignant tumors are capable of metastasis, easy to relapse, poor survival, and low quality of life. In Korea, here is a tendency to treat the tumors collectively according to the General Principles of Cancer Chemotherapy(GPCC) of the Health Insurance Review & Assessment Service (HIRA). But recently, companion diagnostics(CDx) is recommended rather than unilateral medication because biomarker-based molecular diagnostics is possible to predict the drug response of patients before drug treatment. Not only domestic but also overseas Food and Drug Administratio (FDA) recommends the development of the CDx system at the stage of drug development to ensure the responsiveness and safety of medicines. In this study, I focused on the necessity of CDx development direction as well as CDx development status through literature review. Furthermore I also discussed CDx types according to the molecular diagnostic technology such as immunohistochemistry (IHC), polymerase chain reaction (PCR), in situ hybridization (ISH), and next-generation sequencing (NGS) not only in the approved CDx but also in the developing one by US FDA. And I suggested the technology issue of CDx development process such as a selection of molecular diagnostics at the time of release, a clear understanding of the CDx mechanism, and a convergence of drug with CDx development. The necessity of social insurance system also was proposed for CDx development.

A Study on The Influnene of Consulting Paticipation of The Consulted Firm on Consulting Repurchase Intention (수진기업의 컨설팅 참여도가 컨설팅 재구매 의도에 미치는 영향에 관한 연구)

  • Lee, Yang-Woo;Kim, Jung-Ryol;Kim, Sang-Bong
    • Journal of Digital Convergence
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    • v.17 no.1
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    • pp.111-122
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    • 2019
  • This study suggests that even if the consulting is started by the consulting of the company, it is difficult for the consulting firm to operate the consulting firm Consulting performance differs depending on the degree of understanding of consulting. Although consulting firms have been studying various prior research papers in view of the fact that there are many cases where they proceed with the sales strategy of repurchasing in mind, most of them deal with research on consulting performance on the supplier side, The purpose of this study is to investigate whether a company has a high level of participation in consulting in the event of a situation or situation and consequently influences the intention to purchase consulting. In order to find out whether they are visible, the reliability of the measured values and the fit of the measurement model by CFA were obtained through the exploratory factor analysis. The results were as follows: The results of this study are as follows. As a result of the study, it is necessary for the consultant to improve the participation of the consulting company and the understanding of the consulting in order to increase the intention of the consulting repurchase intention. Since the consultant shows the result in an empirical way, the consulting company participates in the role and process The results of this study are as follows. First, it is suggested that firms should be very careful about the participation and consulting understanding because they affect the repurchase intention of consulting firms.

Validity and reliability of the Korean version of the Quality of Recovery-40 questionnaire

  • Lee, Jun Ho;Kim, Deokkyu;Seo, Donghak;Son, Ji-seon;Kim, Dong-Chan
    • Korean Journal of Anesthesiology
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    • v.71 no.6
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    • pp.467-475
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    • 2018
  • Background: The Quality of Recovery-40 (QoR-40) is a widely-used, self-rated, and self-completed questionnaire for postoperative patients. The questionnaire is intended to elicit information from each patient regarding the quality of recovery during the postoperative period. It is noteworthy, however, that an official Korean version of the QoR-40 (QoR-40K) has not been established. The purpose of this study was to develop the QoR-40K by translation and cultural adaptation process and to evaluate the validity and reliability of the QoR-40K. Methods: After pre-authorization from the original author of the QoR-40, the translation procedure was established and carried out based upon Beaton's recommendation to create a QoR-40K model comparable to the original English QoR-40. Two hundred surgical patients were enrolled, and each completed the questionnaire during the preoperative period, on the third day, and 1 month after surgery. The QoR-40K was compared with the visual analogue scale (VAS) and another health-related questionnaire, the Short-form Health Survery-36 (SF-36). The method of validation for QoR-40K included test-retest reliability, internal consistency, and level of responsiveness. Results: Spearman's correlation coefficient for test-retest reliability was 0.895 (P < 0.001), and Cronbach's alpha of the global QoR-40K on the third day after surgery was 0.956. A positive correlation was obtained between the QoR-40K and the mental component summary of SF-36 (${\rho}=0.474$, P < 0.001), and a negative correlation was observed between QoR-40K and VAS (${\rho}=-0.341$, P < 0.001). The standardized responsive mean of the total QoR-40K was 0.71. Conclusions: The QoR-40K was found to be as acceptable and reliable as the original English QoR-40 for Korean patients after surgery, despite the apparent differences in the respective patients' cultural backgrounds.

A Study on the Evaluation of Equality and the Direction of Location Selection for the Concert Hall in Jeju (제주지역 문화행정과 예술경영의 영역설정과 체계정립에 관한 연구)

  • Ko, Hye-Young;Hwang, Kyung-Soo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.3
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    • pp.560-567
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    • 2021
  • The purpose of this study is to examine the concepts of cultural administration and art management, their context, and elements that each concept pursues, and to establish the domains and systems of cultural administration and art management in Jeju. Seven values were selected through the consideration of commonalities and differences and previous studies, and sub-indicators of each value were determined. Factors were analyzed using the AHP method. Cultural administration is based on the areas of publicity, equity, and transparency, while art management is based on productivity, publicity, and responsiveness. Cultural administration needs to focus on a system for the preservation and utilization of local culture, co-evolution of culture, and expansion of culture and arts education. Art management needs to focus on the level of achievement of goals, the level of output versus input, and the system for preserving and utilizing local culture. In addition, it was found that there is a need to establish a system in Jeju with a common aim of the co-evolution of culture and preservation and the utilization of local culture.

A Comparative Study on the Vietnam and the Philippine's Responses to the Chinese Threat in the South China Sea (베트남과 필리핀의 대중국 전략 비교연구: 남중국해 해양 분쟁에 대한 대응을 중심으로)

  • JUN, Sanghyun;LEE, Jeongwoo
    • The Southeast Asian review
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    • v.28 no.4
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    • pp.31-76
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    • 2018
  • This article explores why the two Southeast Asian countries, Vietnam and the Philippines, choose different strategies to cope with the Chinese threat. Despite the evident Chinese threat in the South China Sea, Vietnam has not meaningfully expanded the military cooperation with the United States, whereas the Philippines, ironically, has distanced itself with its ally, the United States. Existing studies on the topic does not offer a satisfactory explanation. We assign that two cases are examples of "underbalancing" - the failure of balancing even though there is an evident threat. Furthermore, we demonstrate the difference between cases of the Philippines and Vietnam by arguing that the number of veto players affects the outcome of foreign policy, underbalancing of two countries. The Philippines has only one veto player, the president, hence its response to external threats is incoherent. On the other hand, the number of veto players in Vietnam is more than one and those players demand negotiation among them on the matter of foreign policy. Upon analyses on two cases we argue that the former is the case of underbalancing caused by a lack of policy stability, while the latter is the case of underbalancing caused by a lack of policy responsiveness.

Artificial Intelligence-based Security Control Construction and Countermeasures (인공지능기반 보안관제 구축 및 대응 방안)

  • Hong, Jun-Hyeok;Lee, Byoung Yup
    • The Journal of the Korea Contents Association
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    • v.21 no.1
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    • pp.531-540
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    • 2021
  • As cyber attacks and crimes increase exponentially and hacking attacks become more intelligent and advanced, hacking attack methods and routes are evolving unpredictably and in real time. In order to reinforce the enemy's responsiveness, this study aims to propose a method for developing an artificial intelligence-based security control platform by building a next-generation security system using artificial intelligence to respond by self-learning, monitoring abnormal signs and blocking attacks.The artificial intelligence-based security control platform should be developed as the basis for data collection, data analysis, next-generation security system operation, and security system management. Big data base and control system, data collection step through external threat information, data analysis step of pre-processing and formalizing the collected data to perform positive/false detection and abnormal behavior analysis through deep learning-based algorithm, and analyzed data Through the operation of a security system of prevention, control, response, analysis, and organic circulation structure, the next generation security system to increase the scope and speed of handling new threats and to reinforce the identification of normal and abnormal behaviors, and management of the security threat response system, Harmful IP management, detection policy management, security business legal system management. Through this, we are trying to find a way to comprehensively analyze vast amounts of data and to respond preemptively in a short time.

The effect of experience factors of untact fashion·beauty performances on customer satisfaction through perceived value (비대면 패션·뷰티 공연의 특성요인이 고객만족에 미치는 영향 -혁신저항의 조절효과를 중심으로-)

  • Lee, Jihyo;Hwang, Dong-Seob;Kim, Kenneth Chi Ho
    • Journal of Digital Convergence
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    • v.19 no.7
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    • pp.327-340
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    • 2021
  • The purpose of this study aims to empirically verify about the impact of the customer satisfaction on the characteristics factors(presence, empathy, responsiveness, and interaction) on the customer satisfaction of 'Asia Model Festival', which was heldis an as untacted fashion and beauty performance that was successfully conducted in Seoul duringinyear 2020. and tThe regulatory effect of innovation resistance in the relationship of the characteristic factors and the customer satisfaction was also reviewed. The analysis showed that the characteristic factors have a positive effect on customer satisfaction, and the innovation resistance is found to control the relationship between interaction, empathy, and the customer satisfaction of the characteristic factors by the subfactor. By identifying the characteristic factors that affect the customer satisfaction of the un-tacted(Zzero Ccontact) visitors, which are expanding due to COVID-19, and studying the effect of controlling the innovation resistance, this study provides a basis for knowing what un-tacted(Zzero Ccontact) visitors need and what services they want to receive, and it presents practical implications and provides basic data for relevant research.

The Effect of Service Quality of Hotel Drive through on Customer Satisfaction and Oncontinuous usage Intention -Focused on Moderating Role of the Hotel Brand image- (호텔 드라이브 스루 서비스품질이 고객만족, 지속이용의도에 미치는 영향 -호텔 브랜드이미지 조절효과 중심-)

  • Kim, Chan-Woo
    • The Journal of the Korea Contents Association
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    • v.21 no.6
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    • pp.513-523
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    • 2021
  • This study verified the effect of Hotel Drive through Service Quality between Customer Satisfaction and Oncontinuous usage Intention. In addition, by injecting the variable of the Hotel Brand Image between Hotel Drive through Service Quality and Customer Satisfaction, we tried to find out the effect of the Moderating Role. Convenience sampling was used for customers who recently experienced Hotel Drive through Service, which is operated mainly in Seoul. It has been held for about 40 days from December 2020. The survey tool constructed through prior research was distributed to customers who experienced Hotel Drive through Service in Seoul. 289 copies of the collected effective samples were statistically processed using SPSS 22.0. As a result of the analysis, it was found that hypothesis 1 and hypothesis 2 had a significant influence relationship. The Tangibility*Hotel Brand Image and physical environment*Hotel Brand Image in Hypothesis 3 were found to have a modulating effect with a significant positive (+) effect. However, it was found that Responsiveness*Hotel Brand Image and Reliability*Hotel Brand Image had no control effect.

A Study on the Properties of Inventory for Efficient Inventory Control at Small-scale Manufacturing Company (소규모 제조기업의 효율적 재고관리를 위한 재고속성에 관한 연구)

  • Kim, Ki Bum;Nam, Gon;Jeong, Yong Moon;Heo, Se min
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.12
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    • pp.449-455
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    • 2020
  • Inventory management is one of the important business functions for manufacturing companies to determine market responsiveness. Customers' needs are diversifying, and the life cycle of products is decreasing, thus increasing the importance of inventory management. However, for small-scale manufacturing companies, investing in an IT system for inventory management is practically difficult. In this study, we introduce an inventory and warehouse management model that can be applied simply and quickly in small-scale manufacturing companies. Firstly, we introduce the concept of the properties of inventory and provide an analytical methodology based on the age and quantity of the inventory. Secondly, in accordance with the properties of the inventory, we introduce location management rules for warehouse operation. To apply the proposed model, we studied a wallpaper manufacturing company and verified the applicability of the proposed methods in the field. The proposed model can be applied immediately as part of on-site improvement activities by small-scale manufacturing companies, and inventory management activities are expected to reduce bad long-term inventory and further secure storage capacity for warehouses.

Development of integrated disaster mapping method (II) : disaster mapping with risk analysis (통합 재해지도 작성 기법 개발(II) : 리스크 분석을 적용한 재해지도 작성)

  • Park, Jun Hyung;Kim, Byunghyun
    • Journal of Korea Water Resources Association
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    • v.55 no.1
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    • pp.85-97
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    • 2022
  • In this study, a method for an integrated flood risk mapping was proposed that simultaneously considers the flood inundation map indicating the degree of risk and the disaster vulnerability index. This method creates a new disaster map that can be used in actual situations by providing various and specific information on a single map. In order to consider the human, social and economic factors in the disaster map, the study area was divided into exposure, vulnerability, responsiveness, and recovery factors. Then, 7 indicators for each factor were extracted using the GIS tool. The data extracted by each indicator was classified into grades 1 to 5, and the data was selected as a disaster vulnerability index and used for integrated risk mapping by factor. The risk map for each factor, which overlaps the flood inundatoin map and the disaster vulnerability index factor, was used to establish an evacuation plan by considering regional conditions including population, assets, and buildings. In addition, an integrated risk analysis method that considers risks while converting to a single vulnerability through standardization of the disaster vulnerability index was proposed. This is expected to contribute to the establishment of preparedness, response and recovery plans for providing detailed and diverse information that simultaneously considers the flood risk including social, humanistic, and economic factors.