• Korean Journal of Applied Biomechanics
• /
• v.23 no.1
• /
• pp.1-9
• /
• 2013

The purpose of this study was to provide information on athletes' characteristics and advantages and disadvantages by analyzing the kinematic factors having a decisive influence on competitive abilities such as release conditions in the delivery phase on major Korean javelin athletes. Two supported javelin throwers of the Korean national team participated in this study. The total average time required of the delivery phase was 0.31(${\pm}0.016$). The athletes' release angle was 33.2 to 41.7 degrees. The attack angle varied widely from -3.5 to 5.9 degrees. The Javelin heights of Subject A and B were 95.9 and 89.2%Ht. The average stride length were 180.6 and 176.7cm. The center of mass velocity of LFD and REL was relatively low in all the subjects. The average deceleration rates of center of mass velocity of Subject A and B were 57.2 and 48.9%lose. The left knee angles of Subject A and B were 160.1 and 155.5 degrees in LFD, 153.0 and 164.0 degrees in REL. The joint velocity of upper limb segments was relatively low in all the subjects. The maximum average wrist velocity of Subject A and B was 18.2 and 16.3 m/s in REL.

• TTA Journal
• /
• s.173
• /
• pp.73-78
• /
• 2017

• 대한약리학회:학술대회논문집
• /
• 2006.11a
• /
• pp.61-61
• /
• 2006

• The Magazine of the IEIE
• /
• v.40 no.4
• /
• pp.34-45
• /
• 2013

• Toxicological Research
• /
• v.21 no.4
• /
• pp.285-290
• /
• 2005

We demonstrate that radicicol, a macrocyclic antifungal antibiotic originally isolated from Monosporium bonorden, inhibits LPS-induced expression of iNOS gene in RAW 264.7 cells. Treatment of peritoneal macrophages and RAW 264.7 cells with radicicol inhibited LPS-stimulated nitric oxide production in a dose-related manner. Immunohistochemical staining of iNOS and RTPCR analysis showed that the decrease of NO was due to the inhibition of iNOS gene expression in RAW 264.7 cells. Immunostaining of p65, EMSA, and reporter gene assay showed that radicicol inhibited $NF-\kappa/Rel$ nuclear translocation. DNA binding, and transcriptional activation, respectively. Collectively, these series of experiments indicate that radicicol inhibits iNOS gene expression by blocking $NF-\kappa/Rel$ nuclear translocation. Due to the critical role that NO release plays in mediating inflammatory responses, the inhibitory effects of radicicol on iNOS suggest that radicicol may represent a useful anti-inflammatory agent.

• Phonetics and Speech Sciences
• /
• v.6 no.2
• /
• pp.153-161
• /
• 2014

The current study reports the results from a cross-modal naming experiment investigating the effects of a prosodic boundary location on the comprehension of ambiguous dative NPs in Korean (Yeongmi-ka Ceonghi-eykey norae-rul pwulecwu-n pwuin-ul ${\cdots}$). The underlined dative NP, Ceonghi-eykey, can temporarily be attached to the embedded rel-marked verb, pwulecwu-n ('sing-rel') or to the matrix verb to appear later. Participants heard sentence fragments manipulated for the location of Intonation Phrase boundary (the biggest prosodic boundary in the model of Seoul Korean) and right after that, had to name visually presented naming targets, which resolve the ambiguity of dative NPs. The prosodic manipulation did not result in difference in naming time, suggesting that the location of a prosodic boundary failed to influence the way Korean listeners interpreted ambiguous dative NPs. Possible reasons for the null effect were discussed.

• Journal of the Korea Institute of Military Science and Technology
• /
• v.15 no.5
• /
• pp.623-629
• /
• 2012

In this paper, we analysis the performance of position estimation when adopting Dynamic TDMA(DTDMA) in JTIDS RelNav. JTIDS RelNav is widely understood as a new navigation solution possibly capable to support or take cover of the role of conventional systems including INS or GPS no matter if they are working well or not. By maximizing the efficiency of radio resource management in MAC(Medium Access Control) layer we enhance the system performance without any replacement of hardware.

• International Journal of Industrial Entomology and Biomaterials
• /
• v.37 no.2
• /
• pp.49-54
• /
• 2018

To artificially enhance antimicrobial peptide expression in Bombyx mori, we constructed genetically engineered silkworms overexpressing Rel family transcription factor. The truncated BmRelish1 (BmRelish1t) gene contained a Rel homolog domain (RHD), nuclear localization signal (NLS), acidic and hydrophobic amino acid (AHAA)-rich region, and death domain (DD), but no ankyrin-repeat (ANK) domain. The BmRelish1t gene was controlled by B. mori cytoplasmic actin 3 promoter in the PiggyBac transposon vector. Chromosome analysis of G1 generations of a transgenic silkworm with EGFP expression confirmed stable insertion of BmRelish1t. BmRelish1t gene overexpression in transgenic silkworms resulted in higher mRNA expression levels of B. mori antimicrobial peptides such as lebocin(~20.5-fold), moricin(~8.7-fold), and nuecin(~17.4-fold) than those in normal silkworms.

• Proceedings of the PSK Conference
• /
• 2003.10b
• /
• pp.92.1-92.1
• /
• 2003

In our search for NF-kB inhibitors from natural resources, we have previously identified two structurally related dilignans, manassantin A and B as specific inhibitors of NF-kB activation from Saururus chinensis. However, their molecular mechanism of action remains unclear. We here demonstrate that manassantin A and B are potent inhibitors of NF-kB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-kB. These compounds significantly inhibited the induced expression of NF-kB reporter gene by LPS or TNF-a in a dose-dependent manner. (omitted)

• Proceedings of the Korean Fiber Society Conference
• /
• 1987.06a
• /
• pp.31-32
• /
• 1987