• Journal of Chest Surgery
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• v.51 no.1
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• pp.8-14
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• 2018

Background: Minimally invasive direct coronary artery bypass grafting (MIDCAB) has the advantage of allowing arterial grafting on the left anterior descending artery without a sternotomy incision. We present our single-center clinical experience of 66 consecutive patients. Methods: All patients underwent MIDCAB through a left anterior small thoracotomy between August 2007 and July 2015. Preoperative, intraoperative, postoperative and follow-up data - including major adverse cardiovascular and cerebrovascular events (MACCE), graft patency, and the need for re-intervention - were collected. Results: The mean age of the patients was $69.4{\pm}11.1years$ and 73% were male. There was no conversion to an on-pump procedure or a sternotomy incision. The 30-day mortality rate was 1.5%. There were no cases of stroke, although 2 patients had to be re-explored for bleeding, and 81.8% were extubated in the operating room or on the day of surgery. The median stay in the intensive care u nit and in the hospital were 1.5 and 9.6 days, respectively. The median follow-up period was 11 months, with a 5-year overall survival rate of $85.3%{\pm}0.09%$ and a 5-year MACCE-free survival rate of $72.8%{\pm}0.1%$. Of the 66 patients, 32 patients with 36 grafts underwent a postoperative graft patency study with computed tomography angiography or coronary angiography, and 88.9% of the grafts were patent at $9.7{\pm}10.8months$ postoperatively. Conclusion: MIDCAB is a safe procedure with low postoperative morbidity and mortality and favorable mid-term MACCE-free survival.

• Journal of The Korean Society of Agricultural Engineers
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• v.51 no.4
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• pp.57-66
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• 2009

수학적 모델은 수량과 수질의 예측을 위해 현장 조사의 대안으로 사용되어지며 이러한 모델의 사용과 실측에 불확실성이 존재하게 된다. 불확실성에 대한 많은 연구들이 진행되어 왔으나 시나리오에 의한 모델링 과정에서 발생하는 불확실성에 대한 연구는 미흡한 실정이다. 본 연구에서는 산림이 농경지와 목초지로의 변화에 따른 시나리오를 설계한 후 시나리오 적용에 따른 SWAT (Soil and Water Assessment Tool) 매개변수의 불확실성을 분석하고자 하였다. 몬테카를로 기법 (Monte Carlo simulation)을 이용하여 각 매개변수별 1,000개의 난수를 발생하였으며 앙상블 유량모의 기법을 이용하여 미국 Alabama주 카하바강 상류 (50,967ha)를 대상으로 각 난수별 100개의 유량을 통해 불확실성을 분석하였다. 분석 결과 산림지역이 농경지와 목초지로 변화 되었을 때 유출량이 증가하는 것으로 분석되었으며, 임야가 목초지 보다 농경지로 변화되었을 때 유출량은 더욱 증가하는 것으로 나타났다. 각 시나리오별 SWAT 매개변수의 불확실성은 AWC (Available water capacity), CN (Curve number), GWREVAP (groundwater re-evaporation coeffeicient), REVAPMN (minimum depth of water in shallow aquifer for re-evaporation to occur)순으로 크게 나타났으며, Ksat (Saturated hydraulic conductivity)와 ESCO(Soil evaporation compensation factor)는 유출량의 변화에 큰 영향을 미치지 못하는 것으로 분석되었다. 토지피복별 산림 면적이 클 경우 불확실성이 크게 나타나 산림이 목초지와 농경지로 변함에 따라 불확실성은 감소하는 것으로 나타났다.

• Journal of Korean Biological Nursing Science
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• v.19 no.2
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• pp.51-59
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• 2017

Purpose: The purpose of this study was to identify the retention effects of an individualized dietary education program for hemodialysis patients on diet knowledge, diet self-care compliance, and physiological indices, thus to find the most effective time period for re-education. Method: This study utilized one-group repeated pretest-posttest design. The participants were 52 hemodialysis patients in C hospital, Gyeonggi-Do. Data were collected at 4 and 12 weeks after the education from January through April 2016. Results: There was significant increases in diet knowledge even 12 weeks after the education (p= .007). Diet self-care compliance showed a significant increase at 4 weeks (p= .001), but a decrease at 12 weeks after the education. The level of blood natrium was significantly decreased between 4 and 12 weeks after the education (p= .006). The weight was significantly decreased at 12 weeks after the education. Conclusion: It has been identified that re-education for hemodialysis patients should be implemented between 4 and 12 weeks after education in order to maintain patients' diet self-care compliance, an ultimate aim of diet education. By helping them with their self-care compliance, the patients would maintain their physical and psychological function optimally, thus contributing to a better quality of life among hemodialysis patients.

• Polymer(Korea)
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• v.37 no.4
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• pp.462-469
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• 2013

Catechin (CTEC) is well-known as a very powerful antioxidant, containing the effects of anti-inflammation and skin wound healing. In this study, CTEC/${\beta}$-cyclodextrin (${\beta}$-CD) nanoparticles were incorporated into poly(vinyl alcohol) (PVA)/pectin (PT) hydrogel. The composite was designed for the induction of re-epithelializaton in skin wound. CTEC/${\beta}$-CD nanoparticles were prepared by a molecular complex method. The size of the CTEC nanoparticles formed in the hydrogel was in the range of $250{\pm}17.5$ nm. The incorporation efficiency of CTEC in the nanoparticles was 74%. The cumulative amounts of CTEC released from the hydrogel containing CTEC nanoparticles in the buffers of pH7.4 and 5.5 were $86.51{\pm}3.14%$ and $35.95{\pm}2.14%$ of total CTEC loaded in the hydrogel within 72 h, respectively. Also, in the wound healing test, the CTEC nanoparticles-loaded PVA/PT hydrogel showed faster healing of the wound made in rat dorsum than the CTEC gel.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.46 no.2
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• pp.173-183
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• 2010

In a split beam echo sounder, the transducer design needs to have minimal side lobes because the angular position and level of the side lobes establishes the usable signal level and phase angle limits for determining target strength. In order to suppress effectively the generation of unwanted side lobes in the directivity pattern of split beam transducer, the spacing and size of the transducer elements need to be controlled less than half of a wavelength. With this purpose, a 50 kHz tonpilz type transducer with a half-wavelength diameter in relation to the development of a split beam transducer was designed using the equivalent circuit model, and the underwater performance characteristics were measured and analyzed. From the in-air and in-water impedance responses, the measured value of the electro-acoustic conversion efficiency for the designed transducer was 51.6%. A maximum transmitting voltage response (TVR) value of 172.25dB re $1{\mu}Pa/V$ at 1m was achieved at 52.92kHz with a specially designed matching network and the quality factor was 10.3 with the transmitting bandwidth of 5.14kHz. A maximum receiving sensitivity (SRT) of -183.57dB re $1V/{\mu}Pa$ was measured at 51.45kHz and the receiving bandwidth at -3dB was 1.71kHz. These results suggest that the designed tonpilz type transducer can be effectively used in the development of a split beam transducer for a 50kHz fish sizing echo sounder.

• The Korean Journal of Physiology and Pharmacology
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• v.25 no.1
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• pp.51-58
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• 2021

Oxidative stress-induced neurodegeneration is one of several etiologies underlying neurodegenerative disease. In the present study, we investigated the functional role of histone methyltransferase G9a in oxidative stress-induced degeneration in human SH-SY5Y neuroblastoma cells. Cell viability significantly decreased on H2O2 treatment; however, treatment with the G9a inhibitor BIX01294 partially attenuated this effect. The expression of neuron-specific genes also decreased in H2O2-treated cells; however, it recovered on G9a inhibition. H2O2-treated cells showed high levels of H3K9me2 (histone H3 demethylated at the lysine 9 residue), which is produced by G9a activation; BIX01294 treatment reduced aberrant activation of G9a. H3K9me2 occupancy of the RE-1 site in neuron-specific genes was significantly increased in H2O2-treated cells, whereas it was decreased in BIX01294-treated cells. The differentiation of H2O2-treated cells also recovered on G9a inhibition by BIX01294. Consistent results were observed when used another G9a inhibitor UCN0321. These results demonstrate that oxidative stress induces aberrant activation of G9a, which disturbs the expression of neuron-specific genes and progressively mediates neuronal cell death. Moreover, a G9a inhibitor can lessen aberrant G9a activity and prevent neuronal damage. G9a inhibition may therefore contribute to the prevention of oxidative stress-induced neurodegeneration.

• Journal of The Korea Institute of Healthcare Architecture
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• v.27 no.4
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• pp.51-60
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• 2021

Purpose: Tuberculosis(TB) care unit in public health center should be carefully considered to be re-designed as an infection safety environment for both patient and healthcare workers. So, for the enhancement, this study analyses the facility requirements for co-using the screening clinic as a TB and other respiratory disease care unit. Methods: Not only screening clinic facility guidelines from "A Study for Standard Triage Design and Construction Document" but also the guidelines of TB care and related medical facility are reviewed; KDCA, CDC, ECDC and WHO as a TB care, and FGI and NHS for facility. The facility requirements are summarized space, approach, and mechanical requirement in order. By comparing the summary and screening clinic facility guidelines, supplementations are proposed for TB care unit setting. Results: The result of this study shows that both the space program and mechanical requirement of the screening clinic and that of TB care unit are almost identical and could be share, which include direct airflow or negative air pressure in an exam room. To increase functional and economical efficiency, however, it is necessary to consider a multi-functional negative pressured room, So care process may be re-designed based on a room type; face-to-face room or glass wall inbetween. Implications: The facility guidelines for TB care unit of a public health center should be developed to build a safe environment for infection control by reflecting its medical plan and budget.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.23 no.2
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• pp.51-59
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• 2023

The tracking radar system is installed and operated on the ground, ships, and aircraft, and requires a design to withstand electromagnetic interference with nearby electronic devices. In this case, radiation and immunity standards for cable connection must be satisfied to prevent malfunction of other equipment due to electromagnetic wave interference caused by cables connected to the tracking radar. The radiation standard must also be satisfied so that the electromagnetic wave noise generated and radiated from the tracking radar does not affect the peripheral device, so that the immunity standard for the electromagnetic wave emitted from the peripheral device must be satisfied. In this paper, we propose a design to satisfy MIL-STD-461G including CE, CS, RE, and RS, and explain design satisfaction through tests.

• Journal of the Korean Society of Food Science and Nutrition
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• v.44 no.3
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• pp.418-424
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• 2015

The content of ${\beta}$-carotene in agricultural foods, such as seasonings, tea, vegetables, cereals, nuts & seeds, oils & fats, and fruits, were quantitatively analyzed using reversed-phase HPLC with an UV/visible detector. Standard reference material (SRM) 2385 was used as a control material to validate measurement of ${\beta}$-carotene in this study. Recovery percentage and relative standard deviation of ${\beta}$-carotene in SRM 2385 were 102% and 1.73%, respectively. Vegetables and tea contained relatively high concentrations of ${\beta}$-carotene (young barley powder, $17,293.95{\mu}g/100g$; raw young barley, $2,755.15{\mu}g/100g$; dried green tea leaves, $13,671.85{\mu}g/100g$; green tea powder, $7,579.04{\mu}g/100g$). Contents of ${\beta}$-carotene in nuts & seeds as well as oils & fats ranged from $11.32{\mu}g/100g$ in almond products (roasted with salt) to $58.56{\mu}g/100g$ in perilla seed oil. Among 20 fruits, a high content of ${\beta}$-carotene was found in apricots (raw), which contained $2,280.35{\mu}g/100g$.

• Journal of Advanced Marine Engineering and Technology
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• v.33 no.1
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• pp.44-51
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• 2009

The Characteristics of the flowfield through tube banks with in-line and staggered arrangements were investigated by PIV. Strouhal numbers, velocity vectors and velocity profiles around the cylinders with in-line and staggered arrangements were observed at the pitch ratio Pt/D=2.0 and Reynolds number of Re=$Re=4.0{\times}10^3$. As the results The flow patterns through tube banks were almost a straight line in case of the in-line arrangement while it was almost 八 type in case of the staggered arrangement in the direction of the wake. The average velocity in the rear region of the tube banks with the staggered arrangement was far smaller than that with the in-line arrangement. The Strouhal number in the last rank was far smaller than that in the front ranks in both of the in-line and staggered arrangements. The wake of each cylinder changed with time and with the position of the cylinder.