• Journal of Chest Surgery
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• 제29권4호
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• pp.444-448
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• 1996

작은 인공판막주위 누출에 의한 용혈성 빈혈은 인공판막 치환술후올수 있는 합병증중의 하나이다. 경도의 용혈은 대개 기계 판막으로 대동맥 판막 치환술을 시행했을 때 생기 지만, 드물게는 승모판막 치환 술 후에 생 기도 더욱 드물게 조직판막 치환술 후에도 생 긴다 조직판막 치환술후에 용혈성 빈혈은 거의 생기지 않는다. lonescu-Shiley 심낭판막 치환술을 받은 환자에서 용혈성 빈혈은 승모판막에서는 없었고, 대동맥판막 에서 주로 발생하였다고 보고되 어 왔다. 41세 여자환자가 갑자기 진한적색뇨가생겨 본원에 입원하였다. 이 환자는 10년전 승모판막 폐쇄부전증으로 승모판막 치환술(lonescu-Shiley판막 27mm)을 받았던 병 력 이 있다. 심초음파검사상 판막을 통한 경도의 승모판막 폐쇄부전과 함께 판막의 비후가 관찰되었으나 판막주 위를 통해 세어나오는 판막주위 누출의 소견은 관찰할 수 없었다. 말초혈액도말검사상정적혈구성 정색소성 빈혈을 보였다. 혈액 및 요 검사에서 심한 용혈소견이 보였다. 51. Jude Medical 양엽 판막(size 27mm)으로 승모판막 치환술을 시행하였다. 수술시 lonescu-Shiley 판막에 판엽의 석 회화와 뒤틀림 ( istortion)이 있었고, 술자위 치 에서 1시 방향에 직경 5mm의 작은 판막주위 누출이 발견되었으며 이것이 용혈성 빈혈의 원인으로 생각되었다. 승모판 막 재치환술후 용혈소견은 완전히 사라졌다. 저자들은 작은 인공판막주위 누출에 의한 심한 용혈성 빈혈이 발생한 1예를 경험하였기에 문헌고찰 과 함께 보고하는 바이다.

• Applied Biological Chemistry
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• 제51권3호
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• pp.188-193
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• 2008

수삼을 수분함량 별로 건조한 다음 원형이 변하지 않는 팽화 인삼을 제조할 수 있는 최적의 압력조건을 찾아 팽화 인삼을 제조하고 각 조건 별 시료의 추출수율, 조사포닌, ginsenoside함량 변화를 관찰하였다. 팽화 처리 후 외관상의 가장 큰 변화는 갈변과 부피팽창이었다. 추출수율 측정 결과, 대조군은 37.6%, 팽화 인삼의 경우 $50.0{\sim}62.1%$의 범위로 측정되었다. 조사포닌 함량의 경우 대조군은 11.0 mg/g ginseng, 팽화 인삼은 $19.6{\sim}48.8mg/g$ ginseng의 범위로 측정되었다. 팽화 인삼에서는 홍삼 특유 사포닌인 ginsenoside-Rg3가 검출되었다. Ginsenoside-Rg3의 생성량은 팽화 압력이 증가함에 따라 유의적으로 증가하는 경향을 나타내었다. Ginsenoside-Rg3를 제외한 나머지 기본 ginsenoside와 total ginsenoside함량은 대조군에 비해 모두 증가하였지만, 팽화 압력이 증가함에 따라 그 양이 감소하는 경향을 나타내었다. 따라서 본 연구 결과 인삼을 적절한 조건에서 팽화처리하였을 경우 추출수율, 조사포닌 및 조사포닌 함량의 증진과 일부 ginsenoside의 변형을 확인할 수 있었다.

• 대한불안의학회지
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• 제13권2호
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• pp.132-140
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• 2017

Objective : The Working Alliance Inventory-Short Revised (WAI-SR) has been reported as a reliable, valid and widely used tool for measuring therapeutic alliance. The aim of this study was to assess the reliability and validity of the Korean version of WAI-SR (WAI-SR-K). Methods : A sample of 196 outpatients completed the WAI-SR-K and the data were analyzed for internal consistency and factor structure. Additionally 51 outpatients re-filled WAI-SR-K after two weeks for the test-retest reliability. To test for the validity, questionnaires of treatment satisfaction, and scales including the Korean version of Drug attitude inventory-10 (K-DAI-10) and Hospital anxiety and depression scale (KHADS) were administered. Results : Internal consistency of WAI-SR-K was good (Cronbach's alpha=0.928) and an exploratory factor analysis revealed a two-factor structure. The WAI-SR-K showed a reasonable test-retest reliability (r= 0.810, p<0.01). The total score of WAI-SR-K was positively correlated with K-DAI-10 (r=0.276, p<0.01), and negatively correlated with scores of K-HADS-D (r=-0.217, p<0.01) and K-HADS-A (r=-0.159, p<0.05). Conclusion : The Korean version of Working Alliance Inventory-Short Revised proved to be a reliable and valid instrument for measuring therapeutic alliance in Korean patients with depressive symptoms.

• 유통과학연구
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• 제4권1호
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• pp.27-51
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• 2006

본 연구는 기존의 관계마케팅 관련 연구에서 시장에서의 사회적 유대관계가 소비자 행동에 영향을 미친다는 결과들을 바탕으로, 고객이 가지는 관계를 판매자와 구매자의 관계에서 확장하였다. 즉 기존의 구매자와 판매자 사이의 관계에서 확장하여 구매자와 구매자 사이에 커뮤니티에서의 유대관계 친밀도가 고객관계의 질적 요소인 만족과 신뢰에 미치는 영향과 고객충성도에 유의한 영향을 미치는 가를 파악하고자 하였다. 본 연구의 결과는 다음과 같이 요약할 수 있다. 첫째, 고객-직원간의 유대관계 친밀도는 고객만족과 고객 충성도의 관계에서 유의한 영향을 미치는 것으로 나타났다. 둘째, 고객-고객간의 유대관계 친밀도는 고객만족과 고객 충성도에 유의한 영향을 미치는 것으로 나타났다. 셋째, 고객-고객의 유대관계와 고객-직원의 유대관계는 고객의 신뢰에는 직접적인 영향을 미치지 않는 것으로 나타났다. 이상의 결과를 바탕으로 다음과 같은 전략적 시사점을 제시해 주고 있다. 첫째, 고객이 직원과 가지는 유대관계는 고객이 다른 기업으로 이탈하는 것을 방지할 수 있는 전환장벽의 역할을 할 수 있다. 즉, 기업이 고객을 만족시키고자 하는 이유는 고객이 경쟁기업으로 전환하는 것을 감소시키기 위한 것이라고 할 수 있다. 둘째, 고객의 주변을 둘러싸고 있는 관계가 단순한 고객과 판매원의 관계를 넘어서, 고객과 고객 사이의 관계가 기업에 대한 충성도에 영향을 미친다는 것이다. 셋째, 기업은 고객과 보다 짜임새 있는 섬유조직과 같은 관계를 유지하여야 한다는 것이다.

• Journal of Ginseng Research
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• 제44권6호
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• pp.757-769
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• 2020

Background: Panax quinquefolius and Panax notoginseng are widely used and well known for their pharmacological effects. As main pharmacological components, saponins have different distribution patterns in the root tissues of Panax plants. Methods: In this study, the representative ginsenosides were detected and quantified by desorption electrospray ionization mass spectrometry and high-performance liquid chromatography analysis to demonstrate saponin distribution in the root tissues of P. quinquefolius and P. notoginseng, and saponin metabolite profiles were analyzed by metabolomes to obtain the biomarkers of different root tissues. Finally, the transcriptome analysis was performed to demonstrate the molecular mechanisms of saponin distribution by gene profiles. Results: There was saponin distribution in the root tissues differed between P. quinquefolius and P. notoginseng. Eight-eight and 24 potential biomarkers were detected by metabolome analysis, and a total of 340 and 122 transcripts involved in saponin synthesis that were positively correlated with the saponin contents (R > 0.6, P < 0.05) in the root tissues of P. quinquefolius and P. notoginseng, respectively. Among them, GDPS1, CYP51, CYP64, and UGT11 were significantly correlated with the contents of Rg1, Re, Rc, Rb2, and Rd in P. quinquefolius. UGT255 was markedly related to the content of R1; CYP74, CYP89, CYP100, CYP103, CYP109, and UGT190 were markedly correlated with the Rd content in P. notoginseng.

• Radiation Oncology Journal
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• 제29권3호
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• pp.181-190
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• 2011

Purpose: Thoracic radiotherapy is a major treatment modality of stage III non-small cell lung cancer. The normal lung tissue is sensitive to radiation and radiation pneumonitis is the most important dose-limiting complication of thoracic radiation therapy. This study was performed to identify the clinical and dosimetric parameters related to the risk of radiation pneumonitis after definitive radiotherapy in stage III non-small cell cancer patients. Materials and Methods: The medical records were reviewed for 49 patients who completed definitive radiation therapy for locally advanced non-small cell lung cancer from August 2000 to February 2010. Radiation therapy was delivered with the daily dose of 1.8 Gy to 2.0 Gy and the total radiation dose ranged from 50.0 Gy to 70.2 Gy (median, 61.2 Gy). Elective nodal irradiation was delivered at a dose of 45.0 Gy to 50.0 Gy. Seven patients (14.3%) were treated with radiation therapy alone and forty two patients (85.7%) were treated with chemotherapy either sequentially or concurrently. Results: Twenty-five cases (51.0%) out of 49 cases experienced radiation pneumonitis. According to the radiation pneumonitis grade, 10 (20.4%) were grade 1, 9 (18.4%) were grade 2, 4 (8.2%) were grade 3, and 2 (4.1%) were grade 4. In the univariate analyses, no clinical factors including age, sex, performance status, smoking history, underlying lung disease, tumor location, total radiation dose and chemotherapy were associated with grade ${\geq}2$ radiation pneumonitis. In the subgroup analysis of the chemotherapy group, concurrent rather than sequential chemotherapy was significantly related to grade ${\geq}2$ radiation pneumonitis comparing sequential chemotherapy. In the univariate analysis with dosimetric factors, mean lung dose (MLD), $V_{20}$, $V_{30}$, $V_{40}$, MLDipsi, $V_{20}$ipsi, $V_{30}$ipsi, and $V_{40}$ipsi were associated with grade ${\geq}2$ radiation pneumonitis. In addition, multivariate analysis showed that MLD and V30 were independent predicting factors for grade ${\geq}2$ radiation pneumonitis. Conclusion: Concurrent chemotherapy, MLD and $V_{30}$ were statistically significant predictors of grade ${\geq}2$ radiation pneumonitis in patients with stage III non-small cell lung cancer undergoing definitive radiotherapy. The cutoff values for MLD and $V_{30}$ were 16 Gy and 18%, respectively.

• Journal of Chest Surgery
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• 제29권10호
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• pp.1111-1117
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• 1996

표준형 이오네스큐우심낭판막의 일차성 조직실패상의 특징의 일부를 알아보고져 승모판위치에서 각 각 행콕판막을 적출하였던 56례와 표준형 이오네스큐판막을 적출하였던 연속적 전례인 일차성 조직실 패환자 113례를 대상으로 임상 및 병리학적으로 분석 검토하였다. 양 환자군의 수술당시의 연령은 각각 31.9$\pm$9.2세와 30.4$\pm$ 12.5세였다. 행콕판막은 조직손상으로 인 한 판막폐쇄부전이 빈발한 반면 이오네스큐판막은 석회화변성의 빈도가 높고 협착병변인 경향이 우세 하였다. 판막적출기간은 행콕판막에서보다 이오네스큐판막에서 단축되 었다. 이러한 판막실패의 특징은 판막구조설계의 개선으로 기계적 요소로 인한 판막실패를 감소할 수 있을 것으로 보이나 항광물화상의 개선 없이는 조직판막의 내구성의 개선은 곤난할 것임을 시사하였다.

• 지역사회간호학회지
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• 제18권1호
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• pp.165-176
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• 2007

Purpose: The purpose of this study was to investigate the needs of home care nursing services in relation to the patients in hospital. Method: Subjects were 129 patients who admitted hospital and were selected through convenience sampling. Data were collected using the Home Health Care Need Assessment Questionnaire constructed by the Korea Health Industry Development Institute. Data were analyzed using SAS 8.12 program by applying percentage. Results: 1. According to the diagnosis of the subjects, the majority had cancer (25.0%), followed by musculoskeletal disease (15,6%), neuro/cerebral vascular disease (14.1%), digestive (10.9%) and respiratory disease (10.9%). 2. With regard to fundamental nursing service, subjects wanted to receive home care services for the following reasons: Problem identification and diagnosis (77.5%), vital sign check (49.6%); and intake and output measure (20.9%). 3. With regard to clinical laboratory tests, 62.8% wanted to receive blood tests, and followed by urine tests 26.4%, and wound drainage 26.4%. 4. With regard to medication and treatment service, 40.3% of the subjects wanted to receive intravenous fluid therapy, 26.4% intravenous antibiotics, and 26.4% the monitoring of fluid therapy. 5. With regard to therapeutic nursing service, 33.3% wanted to receive wound care, 26.4% ROM exercise, and 27.9% foley catheter change and care. 6. With regard to educational needs, 42.6% wanted education on infection monitoring, 41.4% on medication, and 34.9% on diet. 7. With regard to counseling needs, 65.9% wanted to receive telephone counseling about patient condition, 52.7% counseling about re-admission and 51.9% direct counseling about patient condition. In the group of injury and toxicity, and cardiovascular/circulatory diseases, 100% wanted telephone and direct counseling about the patient condition. Conclusion: Therefore, in order to improve the quality of hospital based home health care services, various factors that affect to the need of home health care should be analyzed and specified nursing care should be looked into.

• 대한치과교정학회지
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• 제24권4호
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• pp.851-860
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• 1994

Before 1970, mandibular overgrowth was known as main cause of skeletal Class III malocclusion in growing children ; however, recent study reports that many skeletal Class III malocclusion patients also show maxillary deficiency. Since 1972, when Delaire re-accommodated Protraction Head Gear (P.H.G.), many researchers have reported that skeletal Class III discrepancies could be corrected through use of P.H.G., which induces anterior movement of maxilla and change in mandibular growth pattern into infero-posterior direction ; nevertheless, it is very difficult to predict resultant changes of orofacial region. The purpose of this study was to find out what treatment effect P.H.G. has on different study samples. Author divided 51 skeletal Class III malocclusion patients with maxillary deficiency who were treated with P.H.G. into different study groups depending on sex, treatment beginning age, intraoral appliance, and facial growth pattern. By doing so, following results were obtained. 1. Treatment beginning age and Sex Four age groups (5.8 to 8 year-old, 8 to 10 year-old, 10 to 12 year-old, 12 to 14 year-old) were compared, and no significant difference was observed. (p<0.05) There was no significant difference between the sex groups, either. (p<0.05). 2. Intraoral appliance Treatment effects of study groups that used R.P.E.(mean age of 10.2) and Labio-Lingual appliance(mean age of 8.9) were compared. There was no significant difference depending on the type of intraoral appliance that was used. (p<0.05) 3. Facial growth pattern 1) Amounts of SNB and ANB corrections were smaller in clockwise growth pattern group than those in normal or counterclockwise growth pattern group. (p<0.05) 2) Amounts of increase in Wits appraisal and mandibular plane angle were greater in counterclockwise growth pattern group than those in normal or clockwise growth pattern group. (p<0.05) 3)Amounts of increase in articular angle were greater in counter lockwise growth pattern group than those in clockwise growth pattern group. (p<0.05)

• Asian-Australasian Journal of Animal Sciences
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• 제13권5호
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• pp.605-612
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• 2000

Four young swamp buffalo cows of similar age ranging in weight between 280 to 380 kg and trained to do physical work were used in a study to determine energy and protein requirements for draught using a $4{\times}4$ Latin square designed experiment. The experiment consisted of field trials employing 4 levels of work load, e.g. no work as control, and loads amounting 450 to 500 Newton (N) pulled continuously for 1, 2 and 3 h daily for 14 consecutive days. Cows were fed king grass (Penisetum purpuroides) ad libitum and were subjected to materials balance trials. Body composition was estimated in vivo by the body density method and daily energy expenditure (EE) was calculated from ME minus retained energy (RE). The results show that EE while not working ($EE_{resting}$) was $0.42kgW^{0.75}MJ/d$ and maintenance ME ($ME_m$) was $0.37kgW^{0.75}MJ/d$. ME requirement increased to 1.65 times maintenance for the work of 3 hours. The energy expended for doing exercise ($E_{exercise}$) was 9.56, 20.0 and 25.86 MJ/cow for treatments 1, 2 and 3 II, respectively. Fat retention was absent in all groups of working cows, but protein retention was only negative for cows undertaking 3 h work. The relationship between $E_{exercise}$ (MJ), work load (F, kN), work duration (t, h) and body mass (W, kg) was found to be: $E_{exercise}=(0.003F^{1.43}t^{0.93})/W^{0.09}MJ$. The maintenance requirement for digestible protein was $2.51kgW^{0.75}g/d$, whereas digestible protein for growth ($DP_{growth}$) and for work ($DP_{work}$) followed the equations: $DP_{growth}=[(258+1.25W^{0.75}){\Delta}Wkg/d]g$ and $DP_{work}=[12.59e^{0.95t}]g$, respectively The coefficients a, b and c for the calculation of $E_{exercise}$ components according to the Lawrence equation were found to be 2.56 J/kgW.m, 5.2 J/kg load carried.m and 0.29, respectively, thus efficiencies to convert ME into work were 0, 16.09, 27.3 and 32.44% for control, 1, 2 and 3 h/d work, respectively. ME and DP requirements for a 250 to 400 kg working buffalo cow allowing to growth up to 0.5 kg/d are presented.