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Hypolipidemic and Antioxidant Effects to Ginseng Extract (PD:PT = 1) in Apo E Null Mice (Apo E Null mice에서 인삼 Ginsenosides (PD:PT = 1) 추출물의 지질개선 및 항산화 효과)

  • Jang, Soo-Jeong;Kim, Sung-Soo;Lee, Myoung-Sook
    • Journal of Nutrition and Health
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    • v.41 no.7
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    • pp.594-601
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    • 2008
  • Panax ginseng C.A. Meyer (Panax ginseng) has been used for several thousand years to prolong longevity in Asian countries. Ginsenosides are the most active components isolated from ginseng and belong to damarane saponin which are separated into protopanaxadiol and protopanaxtriol. To evaluate the complex effect of ginsenoside in apo E null mice, ginseng extract were intraperioneally (i.p.) injected and provided high-cholesterol diet for 12 weeks. Ginseng extract came from were i.p. injected with dose of 100 mg/kg/day for 4 weeks in the last experimental duration. Ginseng extract used experiment was abundant Rb1, Rc, Re, and Rg1 and PD:PT ratio was 1.2. The high-cholesterol diet induced liver damage was significantly reduced by ginseng extract. Results from plasma lipid profiles and atherogenic index were improved by ginseng extracts. The GE group significantly decreased plasma TG and TC by 73% and 61% compared to apo E (-/-) group. Also ginseng extract tend to decrease lipid profiles and lipidperoxidation contents in liver and heart. Ginseng extract with an abundant amount of Rg1 significantly suppressed the apoptosis induction of cardiac tissue. In conclusion, ginseng extract (PD:PT = 1) was improved lipid profiles and anti-oxidant effects.

LYα LINE FORMATION IN HUBBLE-TYPE SPHERICAL OUTFLOWS IN STARBURST GALAXIES

  • AHN SANG-HYEON;LEE HEE-WON
    • Journal of The Korean Astronomical Society
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    • v.35 no.4
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    • pp.175-185
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    • 2002
  • Almost half of primeval galaxies show P-Cygni type profiles in the Ly$\alpha$ emission line. The main underlying mechanism for the profile formation in these systems is thought to be the frequency re-distribution of the line photons in expanding scattering media surrounding the emission source. A Monte Carlo code is developed to investigate the Ly$\alpha$ line transfer in an optically thick and moving medium with a careful consideration of the scattering in the damping wings. Typical column densities and expansion velocities of neutral hydrogen investigated in this study are $N_{H1}{\~}10^{17-20}\;cm^{-2}$ and ${\Delta}V{\~} 100 km\;s^{-1}$. We investigate the dependence of the emergent profiles on the kinematics and on the column density. Our numerical results are applied to show that the damped Ly$\alpha$ absorbers may possess an expanding H I supershell with bulk flow of ${\~}200 km\;s^{-l}$ and H I column density $N_{H1}{\~}10^{19}\;cm^{-2}$. We briefly discuss the observational implications.

Infection and cox2 sequence of Pythium chondricola (Oomycetes) causing red rot disease in Pyropia yezoensis (Rhodophyta) in Korea

  • Lee, Soon Jeong;Jee, Bo Young;Son, Maeng-Hyun;Lee, Sang-Rae
    • ALGAE
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    • v.32 no.2
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    • pp.155-160
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    • 2017
  • Red rot disease has caused a major decline in Pyropia (Nori) crop production in Korea, Japan, and China. To date, only Pythium porphyrae (Pythiales, Oomycetes) has been reported as the pathogen causing red rot disease in Pyropia yezoensis (Rhodophyta, Bangiales). Recently, Pythium chondricola was isolated from the infected blades of Py. yezoensis during molecular analyses using the mitochondrial cox1 region. In this study, we evaluated the pathogenicity of P. chondricola as an algal pathogen of Py. yezoensis. Moreover, a new cox2 marker was developed with high specificity for Pythium species. Subsequent to re-inoculation, P. chondricola successfully infected Py. yezoensis blades, with the infected regions containing symptoms of red rot disease. A novel cox2 marker successfully isolated the cox2 region of Pythium species from the infected blades of Py. yezoensis collected from Pyropia aquaculture farms. cox2 sequences showed 100% identity with that of P. chondricola (KJ595354) and 98% similarity with that of P. porphyrae (KJ595377). The results of the pathogenicity test and molecular analysis confirm that P. chondricola is a new algal pathogen causing red rot disease in Pyropia species. Moreover, it could also suggest the presence of cryptic biodiversity among Korean Pythium species.

Antioxidant and Skin Anti-Aging Effects of Marigold Methanol Extract

  • Kang, Chul Ho;Rhie, Sung Ja;Kim, Young Chul
    • Toxicological Research
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    • v.34 no.1
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    • pp.31-39
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    • 2018
  • The objective of this study was to evaluate the antioxidant and anti-aging effects of marigold methanol extract (MGME) in human dermal fibroblasts. Total polyphenolic and flavonoid contents in MGME were 74.8 mg TAE (tannic acid equivalent)/g and 85.6 mg RE (rutin equivalent)/g, respectively. MGME ($500{\mu}g/mL$) increased 1,1-diphenyl-2-picryl hydrazyl (DPPH) and 2,2'-azino-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) radical-scavenging, and superoxide dismutase (SOD)-like antioxidant activities by 36.5, 54.7, and 14.8%, respectively, compared with the control. At $1,000{\mu}g/mL$, these activities increased by 63.7, 70.6, and 20.6%, respectively. MGME ($100{\mu}g/mL$) significantly increased the synthesis of type 1 procollagen by 83.7% compared with control treatment. It also significantly decreased Matrix Metalloproteinase-2 (MMP-2) activity and MMP-1 mRNA expression by 36.5% and 69.5%, respectively; however, it significantly increased laminin-5 mRNA expression by 181.2%. These findings suggest that MGME could protect human skin against photo-aging by attenuating oxidative damage, suppressing MMP expression and/or activity as well as by stimulating collagen synthesis.

Fourteen new species of Allobathynella Morimoto and Miura, 1957 from South Korea: with a redescription of A. coreana Morimoto, 1970 (Crustacea, Bathynellacea, Parabathynellidae)

  • Park, Jong-Geun;Cho, Joo-Lae
    • Journal of Species Research
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    • v.5 no.1
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    • pp.49-156
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    • 2016
  • Fourteen new species and A. coreana Morimoto, 1970 of Allobathynella Morimoto and Miura, 1957 are (re-)described and illustrated from the Korean Penninsula. Comparison of the external morphology of these species and two previously known species, A. japonica Morimoto and Miura, 1957 and A. shinjongieei Park and Cho, 2008 enables us to amend the generic diagnosis. A 7-segmented antennule turns out to be inconsistent character due to A. wonjuensis sp. nov., which has a 6-segmented antennule. On the other hand, the exopodal distal segment of thoracopods I-VII with a tiny terminal knob and with outer seta covered by long and strong barbs is proved to be a autapomorphic character of the genus. The 14 new species belong to the mirabilis-group and display more or less similar morphology. However, they differ from A. coreana, A. japonica and A. shinjongieei and from each other not only in quantitative but also in qualitative characters. These differences are summarized in tables. The species inhabit hyporheic zones of rivers and each appears to be highly endemic to a given tributary, having a range limit less than 100 km.

Enhanced effect of magnetic anisotropy on patterned Fe-Al-O thin films

  • N.D. Ha;Kim, Hyun-Bin;Park, Bum-Chan;Kim, C.G.;Kim, C.O.
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2003.03a
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    • pp.239-239
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    • 2003
  • As a result of the recent miniaturization and enhancement in the performance of thin film inductors and thin film transformers, there are increased demands for the thin films with a high magnetic permeability in the high frequency range, a high saturation magnetization, a high electrical resistivity, and a low coercive force. In order to improve high frequency properties, we will investigate anisotropy field by shape and size of pattern. The Fe-Al-O thin films of 16mm diameter and 1$\mu\textrm{m}$ thickness were deposited on Si wafer, using RE magnetron reactive sputtering technique with the mixture of argon and oxygen gases. The fabricating conditions are obtained in the working partial pressure of 2m Torr, O$_2$ partial Pressure of 5%, Input power of 400w, and Al pellets on an Fe disk with purity of 99.9%. For continuous thin film is the 4Ms of 19.4kG, H$\sub$c/ of 0.6Oe, H$\sub$k/ of 6.0Oe and effective permeability of 2500 up to 100MHz. In this work, we expect to enhanced effect of magnetic anisotropy on patterned of Fe-Al-O thin films.

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Color Preferences According to Personality Types in term of Color Attributes (성격특성에 따른 색채의 속성별 의복색 선호도-대구광역시 의류학전공 여대생을 중심으로-)

  • 박화순
    • Journal of the Korean Society of Costume
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    • v.26
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    • pp.87-100
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    • 1995
  • This Paper is intended to analyze color preferences for apparel, and color preferences according to personality types. The subjects are one hundred twenty five female university students majoring in clothing, textile & design. Color stimulus are divided according to season, value and chroma, and personality types are classified into four : introverted, achieving, age-gressive and conservative. Duncan test, factor analysis and descriptive statistics have been applied to data processing. The findings are as follows. In terms of hue preferences, winter colors are most preferred and autumn colors follow. In re-gard to value preferences, low value colors have been found to be preferred and in respect to chroma preferences, low chroma colors have been found to be preferred. Seasonal colors, value and chroma show significant differences at the level of P<.001. In terms of color preferences for apparel fabrics according to personality types, winter colors are most preferred regardless of person-ality types, and autum colors follow. The introverted and the conservative dislike summer colors least and the achieving and the aggress-ive, spring colors. In respect to value preferences, low value colors are preferred irrespective of personality types. The introverted and the achieving dislike high value colors least and the aggressive and the conservative, mid value colors. With regard to chroma preferences, all person-ality types have been found to prefer low chroma colors. They dislike mid chroma color, and high chroma colors are least preferred.

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The case studies on the interiors of the assisted living facilities for the elderly (노인주거복지시설의 실내환경 실태조사 - 한국과 미국 14사례 실태분석 및 설문조사 중심으로 -)

  • Kim, Ha-Young;Chun, Jin-Hee
    • Proceedings of the Korean Institute of Interior Design Conference
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    • 2004.05a
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    • pp.100-105
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    • 2004
  • Recently, the assisted living facilities for the elderly are increasing due to the facts, such as rapid increasing ratio of old people, rising incomes and the changing concepts towards family relationship. For the elderly, there is a need to re-examine how environment can incorporate design concepts which enhance accessibility and adaptability. For this survey each seven cases in Korean & American facilities were examined and also 120 copies of a questionnaire for the elderly who are above 60 were analysed. This survey revealed that; 1. The consciousness of the majority elderly was favorably aware of the assisted living facilities for the elderly by a social phenomenon. 2. At a response of the scale for the living unit, majority subjects preferred to live in size of 16${\sim}$20 pyung. 3. Subjects preferred not only clean and modern atmosphere, but also medical area and fitness room, design considerations for these points are needed. 4. Enough spaces for their hobbies and social activities, which are important factors for smooth understanding, communication and psychological remedy effect for the elderly should be provided in the facilities for the elderly. 5.Korean facilities were lack of accessibility, safety and adaptability, thus it is very important to select the suitable materials for the safety and lighting plans with regard to their physical and mental qualities.

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Malaria Risk Factors in Kaligesing, Purworejo District, Central Java Province, Indonesia: A Case-control Study

  • Cahyaningrum, Pratiwi;Sulistyawati, Sulistyawati
    • Journal of Preventive Medicine and Public Health
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    • v.51 no.3
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    • pp.148-153
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    • 2018
  • Objectives: Malaria remains a public health concern worldwide, including Indonesia. Purworejo is a district in which endemic of malaria, they have re-setup to entering malaria elimination in 2021. Accordingly, actions must be taken to accelerate and guaranty that the goal will reach based on an understanding of the risk factors for malaria. Thus, we analysed malaria risk factors based on human and housing conditions in Kaligesing, Purworejo, Indonesia. Methods: A case-control study was carried out in Kaligesing subdistrict, Purworejo, Indonesia in July to August 2017. A structured questionnaire and checklist were used to collect data from 96 participants, who consisted of 48 controls and 48 cases. Univariate, bivariate, and multivariate analyses were performed. Results: Bivariate analysis found that education level, the presence of a cattle cage within 100 m of the house, not sleeping under a bednet the previous night, and not closing the doors and windows from 6 p.m. to 5 a.m. were significantly ($p{\leq}0.25$) associated with malaria. Of these factors, only not sleeping under a bednet the previous night and not closing the doors and windows from 6 p.m. to 5 a.m. were significantly associated with malaria. Conclusions: The findings of this study demonstrate that potential risk factor for Malaria should be paid of attention all the time, particularly for an area which is targeting Malaria elimination.

Morphological and molecular identification of Alaria paradisea (Phaeophyceae, Laminariales) from the Kurile Islands

  • Klimova, Anna V.;Klochkova, Nina G.;Klochkova, Tatyana A.;Kim, Gwang Hoon
    • ALGAE
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    • v.33 no.1
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    • pp.37-48
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    • 2018
  • Alaria is the second largest genus of the Laminariales, which is distributed far into the northern Pacific and Atlantic oceans. Due to its high morphological plasticity, over 100 specific and sub-specific names have been used in Alaria, this has been tailored down to the present 17 species through morphological revision and molecular phylogenetic analysis. Endemic species of Alaria from Russian Far East have not been thoroughly revised since their original description, and few of them were confirmed using molecular data until recently. We carried out morphological and molecular studies on A. paradisea which is an endemic species distributed on the Kurile Islands, first described by Miyabe and Nagai in 1932 as Pleuropterum paradiseum. The range of morphological variability and its distribution was re-evaluated using the type specimen as well as other specimens. Analyses of partial mitochondrial cytochrome c oxidase subunit 1 and nuclear-encoded internal transcribed spacer sequences showed that A. paradisea nested within the genus Alaria, but differs morphologically from any other Alaria species in having additional sporophylls with a central midrib (${\beta}-sporophylls$). Our results showed that A. paradisea clearly belongs to the genus Alaria based on DNA data, although the key morphological character that was used to include this species to the genus Pleuropterum, ${\beta}-sporophylls$, is stable and distinguishes it from other Alaria species.