• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.13 no.1
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• pp.1-10
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• 2018

Objectives: To evaluate the evidence supporting the effectiveness of Chuna manual therapy for rheumatoid arthritis. Methods: We conducted a search across 9 electronic databases to find all randomized controlled clinical trials (RCTs) that used Chuna manual therapy as a treatment for rheumatoid arthritis. The methodological quality of each RCT was assessed using the Cochrane risk of bias tool. Results: Our inclusion criteria were met by 5 RCTs. The meta-analysis showed positive results for the use of Chuna manual therapy combined with oriental usual care (UC) in terms of the efficacy rate, pain, and duration of morning stiffness when compared to western UC. Positive results were also obtained in terms of the efficacy rate, when Chuna manual therapy combined with medication was compared to medication treatments alone. Conclusions: Our systematic review found encouraging, but limited evidence of Chuna manual therapy for rheumatoid arthritis. However, to obtain stronger evidence without the drawbacks of trial design and the quality of studies, we recommend a comparative research to test the effectiveness of Chuna manual therapy.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.13 no.1
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• pp.35-44
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• 2018

Objectives: To determine the effectiveness of Tai-chi in treatinglow back pain. Methods: We searched 9 electronic databases(Pubmed, CAJ, EMBASE, Cochrane Library, Web of Science, KISS, KISTI, NDSL, and RISS) till April 2018 and included randomized controlled trials(RCTs) that used Tai-chi for lower back pain treatment. The methodological quality of each RCT was assessed usingthe Cochrane risk of bias tool. Results: As per the inclusion criteria, 5 RCTswere found to be eligible for our review. These studies were divided into 4 groups and meta-analysis was performed. The meta-analysis of 1 study showed favorable results regardingthe use of Tai-chi. Twostudies showed favorable results regardingthe use of Tai-chi with Tuina rather than Tuina alone. All studies were observed to have a high risk of bias. Conclusions: There is limited evidence available to support the effectiveness of Tai-chi in relieving low back pain;hence, additionalwell-designed RCTs should be encouraged for better evidence.

• Physical Therapy Rehabilitation Science
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• v.9 no.1
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• pp.55-65
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• 2020

Objective: The most important goal of hippotherapy is to improve function, gait, and balance. The purpose of this study was to investigate the effects of hippotherapy on function, gait, and balance of children with cerebral palsy (CP). Design: A systematic review and meta-analysis. Methods: We've searched the PubMed, EMBASE, and Cochrane Library CENTRAL databases for English experimental studies published up until September 2018. To analyze the effects of hippotherapy on the function, gait, and balance of children with cerebral palsy, the systematic review and meta-analysis were performed on Patient/Participants/Population Problem, Intervention, Comparison, Outcome with Timing, Setting Study Design. Papers retrieved from the database were removed from the literature management database. Methodological quality evaluation was evaluated using Cochrane's risk of bias. Data was analyzed using the Revman 5.3 program of the Cochrane library. Results: In this study, we found that the effect size of hippotherapy, denoted as d, was -3.82, and that hippotherapy had the most effect on gait, but no statistical significant difference was observed. We also found no significant difference in function and balance after hippotherapy. It was found from the funnel plot that there was no publication bias as the plot was symmetrically distributed around the dotted line. Conclusions: There are many unclear studies and a lack of randomized controlled trials (RCTs) in this research area. More RCTs on the effects of hippotherapy on children with CP should be conducted in the future.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.32 no.4
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• pp.90-100
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• 2019

Objectives : The purpose of this study is to determine the safety and efficacy of low level laser. Methods : We searched 11 electronic databases(Pubmed, CAJ, EMBASE, Medline, Cochrane Library, KMBASE, KISS, KISTI, NDSL, RISS, Oasis) up to March 2019. We included randomized controlled trials(RCTs) using low level laser for alopecia. The methodological quality of each RCT was assessed by the Cochrane risk of bias tool. Results : 8 RCT studies were eligible in our review. The meta-analysis of 2 studies showed favorable results for the use of low level laser with minoxidil 5% than minoxidil 5% and 6 studies showed favorable results for the use of low level laser than placebo light. The results of meta-analysis showed that low-level laser has an efficacy on alopecia. There were no serious side effects or adverse effects. High risk of bias were observed in all studies. Conclusion : Now limited evidence is available to support low level laser for alopecia and further well-designed RCTs should be encouraged.

• The Journal of Korean Obstetrics and Gynecology
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• v.30 no.3
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• pp.79-91
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• 2017

Objectives: The purpose of this systematic review is to overview and evaluate the effect on postpartum hypogalactia after acupuncture treatment. Methods: Relevant randomized controlled trials (RCTs) were identified by database searches in Embase, Pubmed, CENTRAL, CNKI, KISS. Searching keywords were "Hypogalactia" or "Hypolactaion" and "Acupuncture". After searching qualified articles, we independently assessed the risk of bias according to the Cochrane Rob criteria. Results: Among the 81 articles five RCTs were finally selected. Four of the selected were statistically significant. One of them was not statistically significant because it was comparative study of chinese medicine and acupuncture treatment. The quality of the evidence for specific comparisons ranged from low to high. Conclusions: Our systematic review found encouraging. Acupuncture treatment would be effective way to increase insufficient milk supply on postpartum hypogalactia.

• Journal of Korean Academy of Nursing
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• v.49 no.3
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• pp.225-240
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• 2019

Purpose: The purpose of this study was to evaluate the effects of reminiscence therapy on depressive symptoms in older adults with dementia using a systematic review and meta-analysis. Methods: Randomized controlled trials (RCTs) published from January 2000 to January 2018 were searched through Research Information Sharing Service (RISS), Korean Studies Information Service System (KISS), Korean Medical Database (KMbase), KoreaMed, PubMed, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Ovid MEDLINE. Two researchers independently performed the search, selection, and coding. Comprehensive Meta-Analysis 3.0 was used for meta-analysis, and Review Manager program 5.3 was used for quality assessment. Results: Out of the 1,250 retrieved articles, 22 RCTs were selected for analysis. The overall effect size of reminiscence therapy for mitigating depressive symptoms in older adults with dementia was -0.62 (95% Cl: -0.92 to -0.31). The effect size was greater in older adults under 80, those with less disease severity, and those for whom the therapy session lasted less than 40 minutes. Conclusion: Reminiscence therapy is an effective non-pharmacological therapy to improve depressive symptoms in older adults with dementia. Because its effectiveness is also influenced by age, disease severity, and application method, it is necessary to consider treatment designs based on individual characteristics as well as methodological approaches.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.14 no.1
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• pp.13-23
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• 2019

Objectives : The purpose of this study was to evaluate the effectiveness of Chuna manual therapy (CMT) for the treatment of tinnitus. Methods : We performed a literature search using eight electronic databases, using related keywords, from January 1990 until the end of April 2019. The randomized controlled trials (RCTs) which evaluated the effectiveness of CMT in the treatment of tinnitus were included in this study. The risk of bias were evaluated using the Cochrane risk of bias tool. Results : Five appropriate RCTs were included and analyzed. The efficacy rate of the CMT group was statistically significantly higher (P<0.03) versus the control group treated with Western medicine, acupuncture, and herbal medicine-only. Conclusions : In this literature review, there was sufficient evidence that CMT is more effective than conventional therapy (including Western medicine, acupuncture, and herbal medicine) in treating tinnitus. However, it should be considered that the included studies lacked any reference of the risk of bias

• Journal of People, Plants, and Environment
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• v.23 no.2
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• pp.125-138
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• 2020

The aim of this study was to review previous literature to determine the effects of nature-based program for workers. This systematic review was conducted in accordance with National Evidence-based Healthcare Collaborating Agency's guidance for undertaking systematic reviews for intervention. Literature search was performed using National Assembly Digital Library, Korean Studies Information Service System, and Korea Education & Research Information Service for literature published until March 2019. The participants were full-time workers, and intervention of nature-based programs was conducted in the outdoor, indoor, and indirect nature contact exposures, with comparators in the control group who did not receive the treatment. The results showed that the programs were effective in physical, psychological, and social health. The methodological quality of randomized controlled trials (RCT) was assessed using the Cochrane Risk of Bias(RoB) tool, while non-randomized controlled trials (N-RCT) were assessed using the Cochrane Risk of bias assessment tool for non-randomized studuies (RoBANS). A total of 16 studies were selected for assessment: two RCTs, 10 N-RCTs, and four one-group pretest-posttest designs. Most interventions were provided at the workplace and in the community. There were many kinds of nature-based interventions, and forest therapy and horticultural therapy programs were most common. Various interventions for workers effectively improved job stress, depression, serum cortisol and stress-response. However, the included studies lacked methodological rigor. Future research is needed to evaluate the long-term effectiveness of nature-based programs for workers using rigorous research designs.

• Korean Journal of Clinical Pharmacy
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• v.32 no.4
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• pp.336-351
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• 2022

Background: Prader-Willi Syndrome (PWS) is a rare genetic disorder. To improve the health deterioration of PWS, investigating optimal treatment options for PWS is required. Thus, we aimed to evaluate the efficacy of pharmacotherapies compared with supportive care or placebos in patients with PWS. Methods: PubMed and EMBASE databases were used to search for randomized controlled trials (RCTs) evaluating the efficacy of pharmacotherapy in PWS patients. Only RCTs that evaluating the efficacy of pharmacotherapy in PWS patients were retrieved. Results: A total of 26 studies were included to evaluate body composition, hormones, glucose levels and hyperphagia behavioral status. Pharmacological treatment group showed a significant decrease of body fat (mean difference (MD): -6.32, 95% confidence interval (CI): -10.58 to -2.06, p=0.004), a significant increase of lean body mass (LBM) (MD: 1.86, 95% CI: 1.43 to 2.30, p<0.00001) and insulin-like growth factor 1 (IGF-1) levels (MD: 241.62, 95% CI: 68.59 to 414.64, p=0.006) compared with the control group. Nevertheless, based on other outcomes evaluated by the current systematic review, pharmacological options showed different efficacy in treating PWS. Conclusion: Pharmacological therapies were effective to decrease significantly in body fat and increase significantly on LBM and IGF-1 levels in patients with PWS. However, still, individualized therapies should be considered in real-world practice in PWS treatment.

• Journal of Acupuncture Research
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• v.40 no.4
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• pp.308-318
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• 2023

To determine the effectiveness of acupuncture in treating restless legs syndrome (RLS), we conducted a literature review of randomized controlled trials (RCTs) that utilized acupuncture as an intervention for patients diagnosed with RLS. Relevant clinical studies (n = 158) from seven databases (the Cochrane Library, PubMed, Embase, CNKI, KISS, RISS, and OASIS) were included based on the inclusion and exclusion criteria and analyzed. Moreover, 6 RCTs were selected for review. In all six studies, it was indicated people who underwent acupuncture treatment showed significant improvements in their overall health. An increase in the treatment efficacy rate, sleep quality, and quality of life indicators after the acupuncture treatment was confirmed. The severity of pain as assessed using the visual analog scale (VAS) scores and International RLS Study Group Rating Scale (IRLSRS) scores and the severity of RLS symptoms were significantly reduced. Any significant side effects were not reported. Acupuncture is suggested as an effective and safe treatment method for RLS. However, further large-scale RCT studies are needed to confirm our findings.