• Title/Summary/Keyword: RAR

Search Result 94, Processing Time 0.031 seconds

Transport Properties of Lennard-Jones Mixtures: A Molecular Dynamics Simulation Study

  • Lee, Song-Hi
    • Bulletin of the Korean Chemical Society
    • /
    • v.29 no.3
    • /
    • pp.641-646
    • /
    • 2008
  • Equilibrium molecular dynamics simulations in a canonical ensemble are performed to evaluate the transport coefficients of several Lennard-Jones (LJ) mixtures at a liquid argon states of 94.4 K and 1 atm via modified Green-Kubo formulas. Two component mixture of A and B is built by considering the interaction between A and A as the attractive (A) potential, that between A and B as the attractive potential (A), and that between B and B as the repulsive potential (R), labelled as AAR mixture. Three more mixtures - ARA, ARR, and RAR are created in the same way. The behavior of the LJ energy and the transport properties for all the mixtures is easily understood in terms of the portion of attractive potential (A %). The behavior of the thermal conductivities by the translational energy transport due to molecular motion exactly coincides with that of diffusion constant while that of the thermal conductivities by the potential energy transport due to molecular motion is easily understood from the fact that the LJ energy of AAR, ARR, and RAR mixtures increases negatively with the increase of A % from that of the pure repulsive system while that of ARA changes rarely.

Evaluation of Ku-band Ground-based Interferometric Radar Using Gamma Portable Radar Interferometer

  • Hee-Jeong, Jeong;Sang-Hoon, Hong;Je-Yun, Lee;Se-Hoon, Song;Seong-Woo, Jung;Jeong-Heon, Ju
    • Korean Journal of Remote Sensing
    • /
    • v.39 no.1
    • /
    • pp.65-76
    • /
    • 2023
  • The Gamma Portable Radar Interferometer (GPRI) is a ground-based real aperture radar (RAR) that can acquire images with high spatial and temporal resolution. The GPRI ground-based radar used in this study composes three antennas with a Ku-band frequency of 17.1-17.3 GHz (1.73-1.75 cm of wavelength). It can measure displacement over time with millimeter-scale precision. It is also possible to adjust the observation mode by arranging the transmitting and receiving antennas for various applications: i) obtaining differential interferograms through the application of interferometric techniques, ii) generation of digital elevation models and iii) acquisition of full polarimetric data. We introduced the hardware configuration of the GPRI ground-based radar, image acquisition, and characteristics of the collected radar images. The interferometric phase difference has been evaluated to apply the multi-temporal interferometric SAR application (MT-InSAR) using the first observation campaigns at Pusan National University in Geumjeong-gu, Busan.

Glycemic Responses of Korean Domestic Measl and Diabetic Meals in Normal Subjects (한국인 대표 식단 및 당뇨 식단의 정상인에 대한 혈당반응)

  • 윤석권;김명애
    • The Korean Journal of Food And Nutrition
    • /
    • v.11 no.3
    • /
    • pp.303-311
    • /
    • 1998
  • This study was carried out to determine the blood glucose responses to 10 kinds of typical Korean domestic meals, 9 kinds of eating out meals and 5 kinds of diabetic meals recommended by hospitals. The levels of blood glucose were measured at 15, 30, 60, 90 and 120 minutes after taking 24 kinds of meals(500$\pm$10㎉) and 50g of glucose to healthy volunteers. The blood glucose response areas and glycemic index(GI) were calculated. There was no invariable tendency of blood glucose responses among diabetic meals, general domestic meals and eating out meals. As the units of grain groups were increased, the GI of meals was increase. When the units of grain groups are same, the side dishes also affected the blood glucose responses, however, it is yet unknown what kinds of food materials of side dishes affected the blood glucose responses. Noodles (Chinese style, kalgugsu(Korean home made) and ramen) lowered blood glucose responses compared to steamed rice. Mixing barley and brown rice with polished rich also lowered blood glucose responses, especially when the mixing ratio of them was over the 15%. The lowering efficiency of barely was greater than brown rice. More than three grain units of rice increased the blood glucose response. The GI was significantly correlated with left area ratio(LAR), right area ratio(RAR) and blood glucose levels at 15, 30, 60, 90 minutes. The RAR and blood glucose levels at 30 minutes profoundly affected the GI.

  • PDF

PHA-Induced Peripheral Blood Cytogenetics and Molecular Anslysis : a Valid Diagnostic and Follow-up Modality For Acute Primyelocytic Leukemia Patients Treated With ATRA and/or Arsenic Tri-oxide

  • Baba, Shahid M;Azad, Niyaz A;Shah, Zaffar A;Afroze, Dil;Pandith, Arshad A;Jan, Aleem;Aziz, Sheikh A;Dar, Fayaz A
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.17 no.4
    • /
    • pp.1999-2006
    • /
    • 2016
  • Background: Acute promyelocytic leukemia (APML) is characterized by the reciprocal translocation t(15;17) (p22;p12) resulting in the PML-$RAR{\alpha}$ fusion gene. A dual diagnostic and follow up approach was applied including cytogenetic demonstration of the t(15;17) translocation and detection dg PML-$RAR{\alpha}$ chimeric transcripts by molecular means. Purpose: Conventional cytogenetics involving bone marrow is beset with high probability of poor metaphase index and was substituted with phytohemagglutinin (PHA)-induced peripheral blood culture based cytogenetic analysis as a diagnostic & follow up modality in APML patients of Kashmir (North India). Both qualitative (RT-PCR) and quantitative (Q-PCR) tests were simultaneously carried out to authenticte the modified cytogenetics. Materials and Method: Patient samples were subjected to the said techniques to establish their baseline as well as follow-up status. Results: Initial cytogenetics revealed 30 patients (81%) Positive for t(15;17) whereas 7 (19%) had either cryptic translocation or were negative for t(15;17). Two cases had chromosome 16q deletion and no hallmark translocation t(15;17). Q-PCR status for PML-$RAR{\alpha}$ was found to be positive for all patients. All the APML patients were reassessed at the end of consolidation phase and during maintenance phase of chemotherapy where 6 patients had molecular relapse, wherein 4 also demonstrated cytogenetic relapse. Conclusions: It was found that PHA-induced peripheral blood cytogenetics along with molecular analysis could prove a reliable modality in the diagnosis and assessment of follow up response of APML patients.

Economic Evaluation on Geosynthetic Reinforced Abutment for Railways (토목섬유로 보강된 철도교대의 경제성 평가)

  • Kim, Dae Sang;Kim, Ung-Jin;Sung, Keun-Yeol;Kim, Hak-Mo
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.19 no.9
    • /
    • pp.508-517
    • /
    • 2018
  • This study evaluated the construction costs of 11 design cases to decrease the horizontal forces applied to an abutment. They include two kinds of abutment types, which are used to improve the backfill materials for reversed T-shaped abutment and geosynthehtic reinforced abutment for railways (RAR). In the first economic analysis, the internal friction angles of the backfill materials were increased from ${\Phi}=35^{\circ}$ to ${\Phi}=40^{\circ}$ and $50^{\circ}$ for a reversed T-shaped abutment. The second analysis examined cases with the design of a geosynthehtic RAR. When the friction angles were $40^{\circ}$ or $50^{\circ}$ after improvement of the backfill material, the reduction in the construction cost of the abutment was not as large (2.0-3.9%), even though the horizontal forces on the abutment were decreased by 18-48%. However, in the case of applying the RAR, a maximum cost reduction of 30% was achieved by decreasing the horizontal force to zero. The cost reduction results from the decreased wall thickness, base slab size, and the number of pile foundations for the abutment, as well as changing the material.

Different Responses to Arsenic Trioxide between NB4 and UF-1, Acute Promyelocytic Leukemia Cell Lines (급성 전골수성 백혈병 세포주간의 삼산화비소에 대한 반응)

  • Kim, Hye-Ran;Choi, Yoon-Jeong;Ryu, Seong-Yeoll;Lee, Young-Seok;Lee, Sang-Hwa
    • Journal of Life Science
    • /
    • v.16 no.5
    • /
    • pp.759-766
    • /
    • 2006
  • Acute promyelocytic leukemia (APL) is a myeloid leukemia caused by over-expression of fusion protein, PML/RAR$({\alpha})$, which was the result of chromosomal translocation and induces the blockage of differentiation of affected promyelocytes. Pharmacological dose of retinoic acid induces the activation of and subsequent degradation of PML/RAR$({\alpha})$ fusion protein, and then APL cells undergo through the normal differentiation pathway. Arsenic trioxide has proved effective in causing remission of acute promyelocytic leukemia by inducing apoptosis of this tumor cells, whereas the heterogeneity of cellular susceptibility to this cytotoxic agent limited its usage on more types of tumors in clinic. This work showed that arsenic trioxide could induce apoptosis of a panel of acute promyelocytic leukemic cell lines, all-trans-retinoic acid (ATRA) sensitive NB4 cells and ATRA resistant UF-1 cell. They were investigated with regard to the correlation between the inherent or intrinsic cellular level of GSH and the apoptotic susceptibility of the cells to arsenic trioxide. We manifested, in two cell types, the inherently existed difference in intracellular GSH level reactive to the arsenic trioxide, and a positive correlation between the GSH level and their apoptotic sensitivity to arsenic trioxide. And it showed that arsenic trioxide could differentiate promyelocytic cancer cells to the cells possessed of dendritic cell surface markers. Unravelling the cause of the different susceptibility between leukemic cells and proving that promyelocyte could be differentiated to dendritic cells by arsenic trioxide will help not only to understand the mechanism underlying the complete remission of acute promyelocytic leukemia induced by arsenic trioxide, but also to expand its clinical usage.