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Musculoskeletal Injuries by Weapons in Korean Soldiers: Four-Year Follow-Up (총기 및 폭발물에 의한 군인의 근골격계 손상: 최근 4년간 분석)

  • Yang, Hanbual;Hwang, Il-Ung;Song, Daeguen;Moon, Gi Ho;Lee, Na Rae;Kim, Kyoung-Nam
    • Journal of the Korean Orthopaedic Association
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    • v.56 no.3
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    • pp.234-244
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    • 2021
  • Purpose: To date, studies of firearm and explosive injuries in the Korean military have been limited compared to its importance. To overcome this, this study examined the characteristics of musculoskeletal damages in soldiers who have suffered firearm and explosive injuries over the past four years. Materials and Methods: From January 2015 to July 2019, military forces who had suffered musculoskeletal injuries from firearms or explosive substances were included. The medical records and radiographs were reviewed retrospectively, and telephone surveys about Short Musculoskeletal Functional Assessment (SMFA) for this group were conducted. To compare the functional outcomes, statistical analysis was performed using a t-test for the types of weapons, and ANOVA for others. Results: Of the 61 patients treated for firearms and explosives injuries, 30 patients (49.2%) were included after undergoing orthopedic treatment due to musculoskeletal injury. The average age at injury was 26.4 years old (21-52 years old). The number of officers and soldiers was similar. Eleven were injured by gunshot and 19 by an explosive device. Sixteen were treated in the Armed Forces Capital Hospital and 10 at private hospitals. More than half of the 16 patients (53.3%) with a fracture had multiple fractures. The most common injury site was the hand (33.3%), followed by the lower leg (30.0%). There were 14 patients (46.7%) with Gustilo-Anderson classification 3B or higher who required a soft tissue reconstruction. Fifteen patients agreed to join the SMFA survey for the functional outcomes. Between officers and soldiers, officers had better scores in the Bother Index compared to soldiers (p=0.0045). Patients treated in the Armed Forces Capital Hospital had better scores in both the Dysfunction and Bother Index compared to private hospitals (p=0.0008, p=0.0149). Conclusion: This is the first study to analyze of weapons injuries in the Korean military. As a result of the study, the orthopedic burden was high in the treating patients with military weapon injuries. In addition, it is necessary to build a military trauma registry, including firearm and explosive injuries, for trauma treatment evaluation and development of military trauma system.

New Functional Properties of Passion Fruit Extract on Skin (패션 프룻 추출물이 피부에 미치는 새로운 기능적 효과)

  • Jeong, Mi Suk;Kim, Soon-Rae;Han, Chang Woo;Kim, Hyeon Jin;Jang, Se Bok
    • Journal of Life Science
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    • v.32 no.2
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    • pp.101-107
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    • 2022
  • In this research, the anti-inflammatory, antioxidant, antiaging, and skin whitening properties of pulp and seed extracts of passion fruit were studied. The result of the primary skin irritation test using a skin-attached patch determined the skin irritation index to be 0.00 for the passion fruit extract. In addition, RAW 264.7 macrophages produce NO by stimulation of lipopolysaccharides, and the application of extracts to this resulted in significantly lower NOs, confirming the excellent anti-inflammatory properties of passion fruit extracts. The 2,2-diphenyl-1-picrylhydrazyl test further confirmed that the passion fruit extract exhibits a good 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonate radical scavenging ability of 5.11% and strong antioxidant properties. The presence of collagen type I in the skin is a measure of aging and various skin diseases. The results obtained from the analysis of the activity of human procollagen I alpha 1 confirmed that the passion fruit extract reduces the synthesis of procollagen. In addition, the skin whitening property of the passion fruit extract was confirmed by the melanin inhibition test, and a sample was obtained that contained more than 2% of arbutin, a whitening agent approved by the Ministry of Food and Drug Safety, which is generally present in the form of a white powder and is used as a functional ingredient. This confirms that the whitening efficacy of the passion fruit extract obtained from nature contributes to the development of functional raw materials for cosmetics and food.

The Decreased Expression of Fbxw7 E3 Ligase Mediated by Cancer Upregulated Gene 2 Confers Cancer Stem Cell-like Phenotypes (CUG2 유전자에 의하여 감소된 FBXW7 E3 ligase 발현이 유사-종양줄기세포 표현형을 유도)

  • Yawut, Natpaphan;Kim, Namuk;Budluang, Phatcharaporn;Cho, Il-Rae;Kaowinn, Sirichat;Koh, Sang Seok;Kang, Ho Young;Chung, Young-Hwa
    • Journal of Life Science
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    • v.32 no.4
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    • pp.271-278
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    • 2022
  • The detailed mechanism by which cancer upregulated gene 2 (CUG2) overexpression induces cancer stem cell-like phenotypes is not fully understood. The downregulation of FBXW7 E3 ligase, a tumor suppressor known for its proteolytic regulation of oncogenic proteins such as cyclin E, c-Myc, Notch, and Yap1, has been frequently reported in several types of tumor tissues, including those in the large intestine, cervix, and stomach. Therefore, we investigated whether FBXW7 is involved in CUG2-induced oncogenesis. In this study, the decreased expression of FBXW7 was examined in human lung adenocarcinoma A549 (A549-CUG2) and human bronchial BEAS-2B cells (BEAS-CUG2) overexpressing CUG2 and compared with control cells stably expressing an empty vector (A549-Vec or BEAS-Vec). Treatment with MG132 (a proteosome inhibitor) prevented the degradation of FBXW7 and Yap1 proteins, which are substrates of the FBXW7 E3 ligase. To address the role of Fbxw7 in the development of cancer stem cell (CSC) phenotypes, we suppressed Fbxw7 protein levels using its siRNA. We observed that decreased levels of FBXW7 enhanced cell migration, invasion, and spheroid size and number in A549-Vec and BEAS-Vec cells. The enforced expression of FBXW7 produced the opposite results in A549-CUG2 and BEAS-CUG2 cells. Furthermore, the downregulation of FBXW7 elevated the activities of EGFR, Akt, and ERK1/2 and upregulated β-catenin, Yap1, and NEK2, while the enforced expression of FBXW7 generated the opposite results. We thus propose that FBXW7 downregulation induced by CUG2 confers CSC-like phenotypes through the upregulation of both the EGFR-ERK1/2 and β-catenin-Yap1-NEK2 signaling pathways.

Machine Transplanting Cultivation with Infant Seedling in Rice Plant I. Effects of Different Nursery Soil and Plumule Length on the Infant Rice Seedling for Machine Transplanting (벼 어린모(유묘) 기계이앙 재배연구 I. 상토종류 및 출아장의 차이가 어린모 기술이앙 재배에 미치는 영향)

  • Yun, Yong-Dae;Oh, Yong-Bee;Lim, Moo-Sang;Park, Rae-Kyeong;Park, Seok-Hong
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.34 no.4
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    • pp.428-433
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    • 1989
  • The objective of this experiment was to determine if there were feasible to transplant infant rice seedling for machine transplanting. Cultivars tested were Sobaegbyeo and Daecheongbyeo, ]aponica type cultivars. Infant seedling, young seedling and semi-adult seedling were raised with sailor rock wool in seedling tray from 1986 to 1988. Infant rice seedling raised more than 4 days after sowing with rock wool was uniform, and low in ratio of missing hill at machine transplanting. Tiller number per m$^2$ was more in infant rice seedling, young seedling and semi-adult seedling, in that order. Heading dates were not significantly different among seedlings applied, however rice plant sown directly was later 4 or 5 days than any other seedlings. Panicle number per m$^2$ was more in infant seedling than in semi-adult seedling, but ripened ratio was lower in infant seedling due to lodging. Thus there were not greatly different in yield among seedlings tested. Therefore infant rice seedling (more than 5cm in plumule length) raised for 7 days was most optimum, and rock wool would be used as a nursery soil instead of nursery soil for raising infant rice seedling in machine transplanting.

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Feed Value of Pearl Millet [Pennisetum americanum(L.) Leeke] Grown as a New Forage Crop (진주조의 사료적 가치)

  • Park, Keun-Yong;Choi, Byung-Han;Kang, Young-Kil;Moon, Hyeon-Gui;Park, Rae-Kyeong
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.33 no.1
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    • pp.48-53
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    • 1988
  • Pearl millet has been detected as a promising new forage crop of excellent quality and productivity since 1985. Its green fodder yields were 10.7 to 12.8 tons per hectare in average of 26 accessions in Suwon, 1985. The yield level was much higher than those of Italian and pro so millets and com. Com was better than Italian and proso millets, and proso millet was better than Italian millet for a green fodder crop. Suwon 1 pearl millet hybrid was the best of the 13 hybrids examined in Suwon, 1986 being 149 tons per hectare of three times cut green fodder yields. The pearl millet hybrid was higher in green fodder yield than com and sorghum/sudan grass hybrids. Leaf area index was 32.4 for the three times cut pearl millet, while 5.8 for the one time cut corn, and 20.8 for the three times cut sorghum/sudan grass. Crude protein content was 16.3 percent for pearl millet being six to five percent higher than corn and sorghum/sudan grass, 11.8 percent for the one time cut at maturity and 16.1 percent for four times cut being higher than corn and sorghum/sudan grass. Crude fat content was 3. percent for pear 1 millet grain being some what higher than corn and sorghum/sudan grass and 1.3-1.4 percent for green fodder crop. Crude fiber content in grain was 1.9 percent for pearl millet 2.6 percent for corn, and 4.3 percent for sorghum/sudan grass. Crude fiber content in pearl millet plant was 24.4 to 26.8 percent, Crude ash content was 2.4 percent in grain and 10.8 to 11.6 percent in the plants of pearl millet hybrid. In vitro digestibility of grain was 93.7 percent for pearl millet, 95.4 percent for corn, and 55.8 percent for sorghum/sudan grass. The digestibility of whole plant was 57.6 to 63.4 percent for pearl millet, 46.3 percent for corn, and 47.3 to 57.6 percent for sorghum/sudan grass. Heavier nitrogen fertilizer applications increased green fodder yields, protein content and digestibility, but reduced fat and ash content of pearl millet inbred line T 186.

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A Study on Estimation of Environmental Value of Tentatively Named 'East-West Trail' Using CVM (CVM기법을 이용한 가칭 '동서트레일'의 환경가치 추정)

  • Kee-Rae Kang;Yoon-Ho Choi;Bo-Kwang Chung;Dong-Pil Kim;Hyun-Kyeong Oh;Woo-Sung Lee;Su-Bok Chae
    • Korean Journal of Environment and Ecology
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    • v.36 no.6
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    • pp.676-683
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    • 2022
  • Due to the effects of rapid changes in the living environment since 2000 and the recent unforeseen pandemic, people are refraining from domestic and international traveling and movement, and outdoor activities for health and the public value of forest trails, called Dullegil Trail in Korea, have become more important. This study estimated the environmental value of the tentatively named "East-West Trail," which connects the forest trails crossing Chungcheong and Gyeongsang Provinces using CVM (Contingent Valuation Method). It surveyed visitors to the East-West Trail, and 725 questionnaires were used for analysis. The average characteristics of respondents were those who exercised 2-3 times per week, visited a forest trail not far from their residence with friends or family, and showed a tendency to spend 50 thousand Korean won or more per visit. Visitors to the Dullegil Trail felt that there was a shortage of information boards on the forest trail, and they preferred a shelter in appropriate locations. We used a double-bounded dichotomous choice (BDDC) logit model proposed by Hanemann to measure the conservation value of the East-West Trail. It was estimated that the environmental value that a visitor to the East-West Trail could obtain was 30,087 won per trip. The estimated environmental value of the East-West Trail can be converted to about 94 billion won total visitors annually based on the population belonging to the direct-use zone near the East-West Trail. As there has been no study on the environmental value of forest trails using CVM, the results of this study will be able to suggest the feasibility of the government policies on forest trails.

First report of Telenomus remus Nixon(Scelionidae), an egg parasitoid of Spodoptera frugiperda(J.E. Smith)(Noctuidae) in Korea and its biological characteristics (한국에서 열대거세미나방 알기생벌 Telenomus remus Nixon (가칭: 밤나방검정알벌)[검정알벌과]의 첫 보고 및 생물적 특성 연구)

  • Jum Rae Cho;Bo Yoon Seo;June Yeol Choi;Gwan Seok Lee;Meeja Seo;Jeong Hwan Kim
    • Korean Journal of Environmental Biology
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    • v.40 no.2
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    • pp.187-198
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    • 2022
  • In this study, Telenomus remus Nixon (Hymenoptera: Scelionidae) was first reported as a natural enemy of the fall armyworm Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae) egg collected from corn fields in Korea, and its biological characteristics was studied. Based on morphological and molecular analysis, the parasitoid emerged from S. frugiperda eggs was identified as T. remus. We found that T. remus can attack the eggs of S. frugiperda, Spodoptera litra and Spodoptera exigua under a laboratory condition. The longevity of T. remus female adult was longer than that of male adult. The egg-to-adult period of T. remus was not affected by the host age and sex. T. remus female adult laid at least 1-3 eggs a day to a maximum of 37 or more eggs, and the most oviposited on the 3rd to 4th day after emergence. The host preference for oviposition of T. remus adult was high in the order of S. litura>S. exigua>S. frugiperda. T. remus preferred to parasitize 1- and 2-day-old host egg rather than 3-day-old host egg. When compared to the sex ratio of T. remus progeny, the rate of female progeny was higher at the initiation time of oviposition, while the proportion of male progeny increased significantly with female adult age, especially after 8-day-old adult. This information may be useful for improving T. remus mass rearing system and developing a biological control program to control S. frugiperda.

Behavioral Mechanism of Hybrid Model of Soil-nailing and Compression Anchor (쏘일네일링과 앵커가 결합된 하이브리드 공법의 거동 메커니즘)

  • Seo, Hyung-Joon;Kim, Hyun-Rae;Jeong, Nam-Soo;Lee, In-Mo
    • Journal of the Korean Geotechnical Society
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    • v.26 no.7
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    • pp.117-133
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    • 2010
  • A hybrid system of soil-nailing and compression anchor is proposed in this paper; the system is composed of an anchor bar (installed at the tip) with two PC strands and a steel bar. After drilling a hole, installing proposed hybrid systems, and filling the hole with grouting material, prestress is applied to the anchor bar to restrict the deformation at the head and/or to prevent shallow slope failures. However, since the elongation rate of PC strand is much larger than that of steel bar, yield at the steel bar will occur much earlier than at the PC strand. It means that the yield load of the hybrid system will be overestimated if we simply add yield loads of the two - anchor bar and PC strands. It might be needed to try to match the yielding time of the two materials by applying the prestress to the anchor bar. It means that the main purpose of applying prestress to the anchor bar should be two-fold: to restrict the deformation at the nail head; and more importantly, to maximize the design load of the hybrid system by utilizing load transfer mechanism that transfers the prestress applied at the tip to the head through anchor bar. In order to study the load transfer mechanism in a systematic way, in-situ pullout tests were performed with the following conditions: soil-nailing only; hybrid system with the variation of prestress stresses from 0 kN to 196 kN. It was found that the prestress applied to the anchor system will induce the compressive stress to the steel bar; it will result in decrease in the slope of load-displacement curve of the steel bar. Then, the elongation at which the steel bar will reach yield stress might become similar to that of PC strands. By taking advantage of prestress to match elongations at yield, the pullout design load of the hybrid system can be increased up to twice that of the soil-nailing system.

Hay Preparation Technology for Sorghum×Sudangrass Hybrid Using a Stationary Far-Infrared Dryer (정치식 원적외선 건조기를 이용한 수수×수단그라스 교잡종의 건초 조제 기술 연구)

  • Jong Geun Kim;Hyun Rae Kim;Won Jin Lee;Young Sang Yu;Yan Fen Li;Li Li Wang
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.43 no.1
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    • pp.22-27
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    • 2023
  • This experiment was conducted to confirm the possibility of preparing Sorghum×sudangrass hybrid artificial hay using far-infrared rays in Korea. The machine used in this experiment is a drying device based on far-infrared rays, and is designed to control temperature, air flow rate, far-infrared radiation amount, and air flow speed. The Sorghum×sudangrass hybrids harvested in late September were wilted in the field for one day, and a drying test was performed on them. Conditions for drying were performed by selecting a total of 7 conditions, and each condition induced a change in radiation amount in a single condition (42%) and two steps (4 treatments) and three steps (2 treatments). The speed of the air flow in the device was fixed at 60 m/s, and the run time was changed to 30, 60, and 90 minutes. The average dry matter (DM) content was 82.84%. The DM content was 59.94 and 76.91%, respectively, in drying conditions 1 and 3, which were not suitable for hay. In terms of drying rate, it was significantly higher than 80% in the 5, 6 and 7 treatment, and power consumption was slightly high with an average of 5.7 kw/h. As for the feed value according to each drying condition, the crude protein (CP) content increased as the drying time increased, and there was no significant difference between treatments in ADF, NDF, IVDMD and TDN content. In terms of RFV, treatment 1, which is a single condition, was significantly lower than the complex condition. Through the above results, it was determined that the drying conditions 4 and 5 were the most advantageous when considering the drying speed, power consumption, and quality.

Does a Preoperative Temporary Discontinuation of Antiplatelet Medication before Surgery Increase the Allogenic Transfusion Rate and Blood Loss after Total Knee Arthroplasty? (항 혈소판 제제의 술 전, 일시적 중단은 슬관절 전치환술 이후의 실혈량 및 동종수혈의 필요성을 증가시키지 않는가?)

  • Cho, Myung-Rae;Lee, Young Sik;Kwon, Jae Bum;Lee, Jae Hyuk;Choi, Won-Kee
    • Journal of the Korean Orthopaedic Association
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    • v.54 no.2
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    • pp.127-132
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    • 2019
  • Purpose: The aim of this study was to determine if preoperative temporary discontinuation of antiplatelet medication (aspirin, clopidogrel, or cilostazol) is a safe procedure that does not increase early postoperative bleeding and allogenic blood transfusion after a total knee arthroplasty. Materials and Methods: A retrospective analysis was conducted among consecutive patients who underwent navigation assisted primary total knee arthroplasty performed by a single surgeon, from January 2013 to December 2016. A total of 369 patients enrolled in this study were divided into two groups, 271 patients with no history of antiplatelet therapy and 98 patients who underwent 7 days of temporary withdrawal of antiplatelet therapy. Comparative analysis between the two groups, on the variation of hemoglobin and hematocrit during the first and second postoperative days, was conducted to determine the amount of early postoperative bleeding and the frequency of allogenic blood transfusion during hospitalization. Results: The variation of hemoglobin, hematocrit during the first and second postoperative days and the frequency of allogenic blood transfusion between no history of antiplatelet medication and discontinuation antiplatelet medication before 7 days from surgery were similar in both groups. Of the 369 patients, 149 patients received a blood transfusion during their hospitalization. Compared to patients who did not receive a blood transfusion, those who did received blood transfusion were significantly older in age, smaller in height, lighter in weight, and showed significantly lower preoperative hemoglobin and hematocrit values. No statistically significant differences in sex, preoperative American Society of Anesthesiologists scores, and the history of antiplatelet medication until 7 days prior to surgery were observed between the two groups according to blood transfusion. Conclusion: Compared to patients with no history of antiplatelet medication, the temporary discontinuation of antiplatelet medication 7 days prior to surgery in patients undergoing antiplatelet medication did not increase the amount of postoperative bleeding or the need for allogenic blood transfusion.