• Journal of the Korean Society of Visualization
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• v.18 no.2
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• pp.59-65
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• 2020

Vertical axis wind energy systems including 3 and 4 blades are numerically investigated in a two-dimensional (2D) computational domain. The power coefficient (C_p) is adopted to measure the efficiency of the system and the effect of the rotating velocity on the power coefficient is analyzed for the two different systems. The rotating velocity varies from 30 rad/s to 90 rad/s, which corresponds to the tip speed ratio (T.S.R) of 0.5 to 1.5. The torque exerted on the blades is mainly determined by the aerodynamic force in the x-direction and maximized when the blade is positioned at around θ = 186°. The efficiency of the 4-blade system is higher than that of the 3-blade system within the tip speed ratio range between 0.5 and 0.67, besides where the 3-blade system shows a better performance. For the 3-blade system, the maximum efficiency is reached to 0.082 at the tip speed ratio of 1.083. The maximum efficiency of the 4-blade system is 0.071 at T.S.R. = 0.92. The velocity fields in the x-direction, pressure fields, and the vorticity magnitude are analyzed in detail for the optimal cases of the 3- and 4-blades systems, respectively.

• Korean Journal of Radiology
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• v.23 no.9
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• pp.921-930
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• 2022

Objective: To identify epidermal growth factor receptor (EGFR) mutations in lung adenocarcinoma based on ¹⁸F-fluorodeoxyglucose (FDG) PET/CT radiomics and clinical features and to distinguish EGFR exon 19 deletion (19 del) and exon 21 L858R missense (21 L858R) mutations using FDG PET/CT radiomics. Materials and Methods: We retrospectively analyzed 179 patients with lung adenocarcinoma. They were randomly assigned to training (n = 125) and testing (n = 54) cohorts in a 7:3 ratio. A total of 2632 radiomics features were extracted from the tumor region of interest from the PET (1316) and CT (1316) images. Six PET/CT radiomics features that remained after the feature selection step were used to calculate the radiomics model score (rad-score). Subsequently, a combined clinical and radiomics model was constructed based on sex, smoking history, tumor diameter, and rad-score. The performance of the combined model in identifying EGFR mutations was assessed using a receiver operating characteristic (ROC) curve. Furthermore, in a subsample of 99 patients, a PET/CT radiomics model for distinguishing 19 del and 21 L858R EGFR mutational subtypes was established, and its performance was evaluated. Results: The area under the ROC curve (AUROC) and accuracy of the combined clinical and PET/CT radiomics models were 0.882 and 81.6%, respectively, in the training cohort and 0.837 and 74.1%, respectively, in the testing cohort. The AUROC and accuracy of the radiomics model for distinguishing between 19 del and 21 L858R EGFR mutational subtypes were 0.708 and 66.7%, respectively, in the training cohort and 0.652 and 56.7%, respectively, in the testing cohort. Conclusion: The combined clinical and PET/CT radiomics model could identify the EGFR mutational status in lung adenocarcinoma with moderate accuracy. However, distinguishing between EGFR 19 del and 21 L858R mutational subtypes was more challenging using PET/CT radiomics.

• Journal of Power Electronics
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• v.18 no.4
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• pp.1086-1098
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• 2018

This study presents a new sensorless commutation method for brushless direct current motors to replace Hall sensor signals with virtual Hall signals. The importance of the proposed method lies in the simultaneous elimination of the phase shifter and the low-pass filters, which makes the method simple and cost-effective. The method removes high ripple switching noises from motor terminals, thereby decreasing motor losses. The proposed method utilizes unfiltered line voltages with notches caused by current commutation. Hence, specific sign signals are defined to compensate for the effects of commutation noise. The proposed method is free from phase delay that originates from low-pass filters. The method directly produces virtual Hall signals, and thus, it can be interfaced with low-cost commercial commutation integrated circuits based on Hall sensors. Simulation and experimental results show the effectiveness and validity of the proposed method.

• Radiation Oncology Journal
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• v.5 no.1
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• pp.13-21
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• 1987

The effect of local hyperthermia of 41 to $43^{\circ}C$ for 30 minutes on radiosensitivity of normal tissue was studied utilizing jejunal crypt microcolony assay. Hyperthermia of this range enhanced the radiation effect and the effect was mainly additive without significant effect on the slopes of cell survival curves. At the isoeffect level of 20 microcolony formation, the thermal enhancement ratio was 1.02, 1.10 and 1.39 for $41^{\circ},\;42^{\circ}\;and\;43^{\circ}C$, respectively. The distribution of microcolony formation along the circumference of jejunum was not uniform, having more colonies around the mesenteric border, and this suggests the effect of uneven cooling by blood circulation.

• The Journal of Korean Society for Radiation Therapy
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• v.18 no.1
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• pp.29-34
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• 2006

Purpose: The radioprotective effects of white and fermented ginseng on liver damage induced by $^{60}Co\;{\gamma}$-ray were investigated. Materials and Methods: To one group of ICR male mice were given white(150 mg/kg/day for 7 days, orally) and fermented ginseng(150 mg/kg/day for 7 days, orally) before $^{60}Co\;{\gamma}$-ray irradiation. To another group were irradiated by 5 Gy(1.01 Gy/min) dose of $^{60}Co\;{\gamma}$-ray. Contrast group were given with saline(0.1 mL). The levels of reduced(GSH) and oxidized(GSSG) glutathione in liver tissue were measured. Results: In the fermented(150 mg/kg) and white ginseng(150 mg/kg) groups than irradiation group, the GSH levels were significantly increased, but the GSSG levels were significantly decreased. The ratio of GSSG/total GSH was significantly decreased in the fermented(150 mg/kg) and white ginseng(150 mg/kg) groups than irradiation group. Conclusion: In the fermented(150 mg/kg) groups than white ginseng(150 mg/kg) groups the GSH levels were significantly increased. The radioprotective effects of fermented(150 mg/kg) groups than white ginseng(150 mg/kg) groups were increased.

• Journal of Astronomy and Space Sciences
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• v.18 no.1
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• pp.71-80
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• 2001

The threshold voltage shift observed in TDE (Total Dose Experiment) on board the KITAT-1 is converted into dose (rad($SiO_2$)) using the result of laboratory calibration with Co-60 gamma ray source in KAERI (Korea Atomic Energy Research Institute). Simulation using the NASA radiation model of geomagnetosphere verifies that the dose difference between RADFET1 and RADFET3 observed on KITSAT-1 comes from the difference in shielding thickness at the position of these RADFETs.

• Journal of the Korean Magnetic Resonance Society
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• v.22 no.1
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• pp.18-25
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• 2018

Replication protein A (RPA) is an essential single-stranded DNA binding protein in DNA processing. It is known that N terminal domain of RPA70 (RPA70N) recruits various protein partners including damage-response proteins such as p53, ATRIP, Rad9, and MRE11. Although the common binding residues of RPA70N were revealed, dynamic properties of the protein are not studied yet. In this study, we measured $^{15}N$ relaxation parameters ($T_1,\;T_2$ and heteronuclear NOE) of human RPA70N and analyzed them using model-free analysis. Our data showed that the two loops near the binding site experience fast time scale motion while the binding site does not. It suggests that the protein binding surface of RPA70N is mostly rigid for minimizing entropy cost of binding and the loops can experience conformational changes.

• Journal of Chest Surgery
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• v.17 no.4
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• pp.607-613
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• 1984

Thirty seven patients with ostium secundum atrial septal defect, operated from January, 1976 to September, 1984 at the Department of Thoracic and Cardiovascular Surgery, Kyungpook National University Hospital, were given clinical assessment. The following results were obtained. 1.Ostium secundum atrial septal defect was comprised of 18% of congenital heart disease. Their mean age was 15.7\ulcorner.42. Sex ratio [male:female] was 1:1.1. 2.Most frequent clinical symptom was dyspnea on exertion occurred in 26 patients [76.5%]. Only one patient had no symptom [2.9%]. 3.Pre-operative EKG findings revealed RVH in 61.8%, ICRBBB in 29.4%, and RAD in 41.2%. 4.Mean value of systolic pulmonary arterial pressure in patients over 20 years old was 37.8\ulcorner4.4mmHg and it was 28.1\ulcorner10.2mmHg in patients under 20 years old, but the difference between two groups was not statistically significant. 5. In large defect group [>3cm in diameter], Qp/Qs was significantly increased than small defect group [<3cm in diameter], but systolic pulmonary arterial pressure and Rp/Rs were not different between two groups. 6. Overall operative mortality was 5.4%.

• Environmental Analysis Health and Toxicology
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• v.18 no.4
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• pp.287-294
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• 2003

출아형 효모 Saccharomyces cerevisiae RAD3 유전자는 절제회복 및 세포의 생존에 필수적이며, DNA dependent ATPase와 DNA-RNA helicase활성을 가지고 있는 것으로 알려져 있다. 본 연구는 분열형 효모 Schizosaccharomyces pombe에서 절제회복과 세포의 생존에 필수적인 출아형 효모 RADS유전자와 유사한 유전자를 S. pombe genomic DNA library에서 분리하여 그 특성을 연구하였다. 분리한 RADS 유사유전자를 HRD3 유전자라 명명하였다. 발현 vector pET3a를 이용하여 분리한 HRD3 유전자를 과 발현하였을 때 HRD3단백질은 숙주단백질의 합성 억제 또는 분해 촉진을 유발하여 숙주세포인 대장균에 독성 효과를 나타냄이 관찰되었다. HRD3유전자와 lacZ유전자를 융합시킨 여러 가지 재조합 vector를 만들어 이들 융합단백질을 분리하였다. 이 결과 HRD3단백질의 카르복실 말단 부위가 DNA회복기능과 대장균에서의 독성효과를 나타내는 중요한 부위로 생각된다.

• Steel and Composite Structures
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• v.18 no.5
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• pp.1177-1195
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• 2015

Six specimens are tested to investigate the cyclic behavior of beam-to-column abnormal joints in steel moment-resisting frames, which are designed according to the principle of strong-member and weak-panel zone. Key parameters include the axial compression ratio of column and the section depth ratio of beams. Experimental results indicate that four types of failure patterns occurred during the loading process. The $P-{\Delta}$ hysteretic loops are stable and plentiful, but have different changing tendency at the positive and negative direction in the later of loading process due to mechanical behaviors of specimens. The ultimate strength tends to increase with the decrease of the section depth ratio of beams, but it is not apparent relationship to the axial compression ratio of column, which is less than 0.5. The top panel zone has good deformation capacity and the shear rotation can reach to 0.04 rad. The top panel zone and the bottom panel zone don't work as a whole. Based on the experimental results, the equation for shear strength of the abnormal joint panel zone is established by considering the restriction of the bottom panel zone to the top panel zone, which is suitable for the abnormal joint of H-shaped or box column and beams with different depths.