• Perinatology
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• v.29 no.4
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• pp.170-174
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• 2018

Objective: Progesterone is used to prevent recurrent preterm delivery, however the molecular mechanisms of its effect are incompletely understood. The objective of this study was to determine the effect of progesterone on tumor necrosis factor $(TNF)-{\alpha}$-induced matrix metalloproteinase (MMP)-9 activity in human choriodecidual (CD) membranes. Methods: We collected CD membranes from women with uncomplicated term pregnancies who were scheduled for elective cesarean delivery (n=10). CD membranes ($1{\times}1cm$) were incubated in tissue culture media at $37^{\circ}C$. We pre-treated the CD membranes with progesterone (P4), $17{\alpha}$-hydroxyprogesterone caproate (17P), promegestone (R5020), or vehicle (ethanol) for 24 hours. The CD membranes were subsequently treated with $TNF-{\alpha}$ (with continued progesterone treatment) for 48 hours, then media was harvested for measuring MMP-9 activity by zymography and total protein was isolated from CD membrane tissues for MMP-9 expression by western blot analysis. Results: P4, 17P, and R5020 significantly reduced $TNF-{\alpha}$-induced MMP-9 activity in fetal membrane tissue samples (P=0.0078, P=0.0156, and P=0.0391, respectively) by zymography. Western blot analysis also showed decreased expression of MMP-9 in progesterone pretreated groups (P=0.0313). Conclusion: Progesterone reduces $TNF-{\alpha}$-induced MMP-9 activity in human CD membranes. These findings may provide further support for the role of progesterone in preventing preterm birth.

• Bulletin of the Korean Chemical Society
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• v.7 no.3
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• pp.170-178
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• 1986

The NMR chemical shift arising from 4d electron angular momentum and 4d electron angular momentum and 4d electron spin dipolar-nuclear spin angular momentum interactions for a $4d^1$ system in a strong crystal field environment of trigonal symmetry, when the threefold axis is chosen to be the axis of quantization axis, has been examined. A general expression using the nonmultipole expansion method (exact method) is derived for the NMR chemical shift. From this expression all the multipolar terms are determined. We observe that along the (100), (010), (110), and (111) axes the NMR chemical shifts are positive while along the (001) axis, it is negative. We observe that the dipolar term (1/R3) is the dominant contribution to the NMR chemical shift except for along the (111) axis. A comparison of the multipolar terms with the exact values shows also that the multipolar results are exactly in agreement with the exact values around $R{\geqslant}0.2$ nm. The temperature dependence analysis on the NMR chemical shifts may imply that along the (111) axis the contribution to the NMR chemical shift is dominantly pseudo contact interaction. Separation of the contributions of the Fermi and the pseudo contact interactions would correctly imply that the dipolar interaction is the dominant contribution to the NMR chemical shifts along the (100), (010), (001), and (110) axes, but along the (111) axis the Fermi contact interaction is incorrectly the dominant contribution to the NMR chemical shift.

• Journal of Cerebrovascular and Endovascular Neurosurgery
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• v.25 no.4
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• pp.380-389
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• 2023

Objective: Middle meningeal artery embolization (MMAe) has burgeoned as a treatment for chronic subdural hematoma (cSDH). This study evaluates the safety and short-term outcomes of MMAe patients relative to traditional treatment approaches. Methods: In this retrospective large database study, adult patients in the National Inpatient Sample from 2012-2019 with a diagnosis of cSDH were identified. Cost of admission, length of stay (LOS), discharge disposition, and complications were analyzed. Propensity score matching (PSM) was utilized. Results: A total of 123,350 patients with cSDH were identified: 63,450 without intervention, 59,435 surgery only, 295 MMAe only, and 170 surgery plus MMAe. On PSM analysis, MMAe did not increase the risk of inpatient complications or prolong the length of stay compared to conservative management (p>0.05); MMAe had higher cost ($31,170 vs. $10,768, p<0.001) than conservative management, and a lower rate of nonroutine discharge (53.8% vs. 64.3%, p=0.024). Compared to surgery, MMAe had shorter LOS (5 vs. 7 days, p<0.001), and lower rates of neurological complications (2.7% vs. 7.1%, p=0.029) and nonroutine discharge (53.8% vs. 71.7%, p<0.001). There was no significant difference in cost (p>0.05). Conclusions: MMAe had similar LOS and decreased odds of adverse discharge with a modest cost increase compared to conservative management. There was no difference in inpatient complications. Compared to surgery, MMAe treatment was associated with decreased LOS and rates of neurological complications and nonroutine discharge. This nationwide analysis supports the safety of MMAe to treat cSDH.

• Natural Product Sciences
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• v.11 no.3
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• pp.170-173
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• 2005

Compounds of (+)-5,5'-dimethoxylariciresinol (1) and (3S,5R,6S,7E)-5,6-epoxy-3-hydroxy-7-megastigmen-9-one (2) were isolated from an EtOAc extract of the whole plant of Sasa borealis (Hack.) Makino (Gramineae) for the first time in the present investigation. The structures of compounds were identified by analysis of spectral data including 1D- and 2D-NMR spectra as well as by comparison of their data with the published values. These compounds have never been isolated previously from the family Gramineae.

• Molecular & Cellular Toxicology
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• v.4 no.2
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• pp.170-176
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• 2008

The quantitative structure-activity relationship (QSAR) of a set of 35 flavonoid compounds presenting antioxidant activity was established by means of Genetic Algorithm-Multiple Linear Regression (GA-MLR) technique. Four-parametric models for two sets of data, the 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical scavenging activity $(R^2=0.788,\;Q^2_{cv}=0.699\;and\;Q^2_{ext}=0.577)$ and scavenging activity of reactive oxgen species (ROS) induced by $H_2O_2 (R^=0.829,\;Q^2_{cv}=0.754\;and\;Q^2_{ext}=0.573)$ were obtained with low external predictive ability on a mass basis, respectively. Each model gave some different mechanistic aspects of the flavonoid compounds tested in terms of the radical scavenging activity. Topological charge, H-bonding complex and deprotonation processes were likely to be involved in the radical scavenging activity.

• Proceedings of the Acoustical Society of Korea Conference
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• autumn
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• pp.167-170
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• 2001

본 논문에서는 미국에서 고 선명(High Definition) TV를 위한 오디오 표준인 ATSC에 의해서 채택되고, DVD의 오디오 코덱으로 널리 채택된 Dolby AC-3 복호화기를 고정 소수점으로 변환한 후, ARM929T를 기반으로 실시간 구현하였다. 실시간 구현에 사용된 ARM920T 는 저전력 소비형 32-비트 고정 소수점 RISC 구조이며, 명령어 Cache 와 데이터 Cache, MMU(Memory Management Unit)로 구성되어 있다. 그리고 200MIPS 의 성능을 가지고 있어, 음성/오디오, 통신, 디지털 셀룰라폰에 적용할 수 있고, ASIC 화 할 수 있는 장점을 가지고 있다. 구현된 AC-3 복호화기는 약 67MIPS(6 채널, 640kbps, 48KHz)의 복잡도를 나타내며, 사용된 메모리양은 프로그램 ROM 23.3K Bytes, 데이터 ROM(table) 4.62K Bytes 및 RAM 45K Bytes 이다. 구현된 AC-3 복호화기는 Dolby사에서 제공하는 40 개의 test 벡터들을 bit-exact하게 통과하였다.

• 한국신재생에너지학회:학술대회논문집
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• 2009.11a
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• pp.313-320
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• 2009

Indonesian Ministry of Environment estimates that each year 170 cities and regencies in Indonesia produce 45,764,354.30 $m^3$ or approximately 11,441,091.08 ton of solid waste. Unfortunately, unsustainable management system has created a severe waste problem, hazardous to health and environment. This paper deals with the problem and offers some solutions. They are 3R (Reduce Reuse and Recycle), waste-to-energy concept and landfill gas (LFG) utilization. While 3R policy has been adopted by the government, the remaining two technologies are still dormant. Thus the paper provides a complete yet compact analysis of technology, economics, and environment aspect of waste-to-energy and LFG. Given the facts of waste production and management in Indonesia, the purpose is to encourage Government of Indonesia and other stake holders (including international community) to explore and exploit this potential. Potential of reducing waste negative externality while receiving extra revenue. Two bird with a stone.

• Journal of electromagnetic engineering and science
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• v.6 no.3
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• pp.165-170
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• 2006

In this paper, magneto-dielectric material is proposed to use for minimizing antenna size. One examle of very small antenna is presented to prove this with antenna's area of $0.078\lambda_0\times0.016\lambda_0$, and just moderate values of permittivity and permeability while the return loss can reach - 38 dB at the resonant frequency. The parameters of dielectric material for that best performance are $\varepsilon_r=1.71-j0.004$, and $\mu_r=2.39-j2.58$. Besides, this material also has ability to control the trade-off between the gain and bandwidth while keeping the antenna size unchanged.

• Journal of Power System Engineering
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• v.11 no.1
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• pp.56-62
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• 2007

This paper represents the cold energy for liquefied nitrogen gas and cascade refrigerator. In this study, the vaporizer of liquefied nitrogen gas has the fin coil tube type with the dimension of inside diameter of 10mm and outside diameter of 12mm. Also, the total length of vaporizer is 20,000mm. The main experimental parameters are the mean velocity in duct and the supplied flow-rates of liquefied nitrogen gas. For the cascade refrigeration system, the refrigerants are ethane(R 170) in the high pressure stage and R 22 in the low pressure stage.

• Journal of Electrical Engineering and Technology
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• v.13 no.2
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• pp.881-885
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• 2018

In order to develop a gas circuit breaker (GCB), the breaking performance of the short line fault (SLF) should be prioritized over that of the breaker terminal fault (BTF). In brief, it is necessary to evaluate the thermal characteristics of the insulating gas that is filled in a GCB. In the process of developing a GCB, many companies use the simplified synthetic testing facility (SSTF).In order to evaluate the SLF breaking performance of a GCB with a long minimum arcing time, a modifications to the conventional SSTF was proposed. In this study, we developed the SSTF with a modified transient recovery voltage circuit. The performance of the newly developed SSTF was verified by an $L_{90}$ breaking performance test on a rating combination of 170 kV, 50 kA, and 60 Hz.