• Title/Summary/Keyword: R-groups

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A TEM STUDY OF THE RESIN-DENTIN INTERDIFFUSION ZONE FORMED BY ONE-BOTTLE DENTIN ADHESIVE SYSTEMS (단일용기 상아질 접착제 처리 후 레진-상아질 경계면에 대한 투과전자현미경적 연구)

  • Yang, Dong-Woon;Park, Seong-Ho;Lee, Chan-Young
    • Restorative Dentistry and Endodontics
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    • v.25 no.2
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    • pp.180-192
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    • 2000
  • One bottle system was recently developed in order to simplify the clinical skills and save chair time after continuous improvements on dentin bonding agents. There has been many studies to measure the bond strength of one bottle systems but no actual work has been done on micromorphologic study of resin-dentin interdiffusion zone after one bottle system application. To evaluate the bonding patterns of various commercially available one bottle systems to dentin, observation of resin-dentin interdiffusion zone under TEM was performed. Caries-free human third molars within one month of extractions were chosen for the experiments. The molars were sectioned 1mm above the cementoenamel junction and got rid of the root portions. Crown portions of the teeth were sectioned parallel to occlusal surface so that dentin discs of 1mm in thickness were remained. 7 one bottle systems and 1 two bottle system were applied according to manufacturer's instructions and followings were the results. 1. In every experimental groups, cross bandings of collagen fiber were distinguishable and tight bon dings between the bonding agents and dentin were observed. 2. Hybrid layer was clearly observed in ONE-STEP$^{(R)}$, Prime & Bond$^{(R)}$ 2.1, Syntac$^{(R)}$ SC, MAC-BOND II groups but it was not clear in Single Bond, D-Liner Dual PLUS, ONE COAT BOND groups. 3. Electron-density of hybrid layer was uniform in pattern in MAC-BOND II, Prime & Bond$^{(R)}$ 2.1 groups but not so uniform in ONE-STEP$^{(R)}$ group. 4. Electron-dense amorphous phase in most superior layer of the resin-dentin interdiffusion zone was characteristically observed in Single Bond, Syntac$^{(R)}$ SC, ONE COAT BOND groups. It can be concluded that bondings between the dentin bonding agents and dentin can be various in pattern according to their chemical compositions and the condition during applications.

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Effect of Sustained Release Recombinant Bovine Somatotropin on Semen Characteristics and Sexual Behavior in Dairy Young Bulls (소 성장호르몬 투여가 젖소 후보 종모우의 정액 성상 및 성 행동 양식에 미치는 영향)

  • Jeong, J.;Shin, J.S.;Kim, J.B.;Yang, B.K.;Hong, B.J.
    • Korean Journal of Animal Reproduction
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    • v.20 no.2
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    • pp.197-205
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    • 1996
  • This study was conducted to examine the effect of sustained release recombinant bovine somatotropin(SR-rBST) with different dosage(0, 0.03mg/kg body weight/14 day, 0.06mg/kg body weight/14 day, 0.09mg/kg body weight/14 day) on the economical traits of the semen characteristics and sexual behaviors and blood chemical values with sixteen Holstein dairy young bulls in Dairy Cattle Improvement Center of National Livestock Co-operatives Federation. Sensual testings of collected semens of Holstein young bulls were not different among treatments (p>0.05). Ejaculated semen volumes of control, SR-rBST 0.03mg, 0.06mg and 0.09mg groups were 5.6ml, 5.6ml, 6.0ml and 6.7m, respectively, but the result of SR-rBST 0.09mg group significantly increased semen volume(P<0.05). In sperm concentration, SR-rBST 0.06mg and 0.09mg groups significantly increased the total number of sperms than the other groups(P<0.05). In otherwise, SR-rBST treatments did not affect on pH, osmotic pressure, anti forzen rate, abnormality and motility of collected semen during whole experimental period. Reaction time(RT), sexual aggressiveness(SA) and tactile stimulation(TS) were not different among treatments. The libido scores(LS) of control, 0.03mg, 0.06mg and 0.09mg groups were 68.0, 80.5, 73.9 and 80.8, respectively, and LS were significantly improved by SR-rBST administration(P<0.05). The effect of SR-rBST on scrotal circumference measurement that is important factor to determine the ability of semen production, was not different among treatments. These studies indicates that SR-rBST treatments favourably affect on semen quality and sexual libido in Holstein young bull.

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The Difference of Cognitive Styles between Research & Management Staff on R & D Management (연구개발관리에 관한 연구직과 행정직의 인지차이 연구)

  • 민웅기
    • Journal of Technology Innovation
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    • v.3 no.1
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    • pp.83-108
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    • 1995
  • The two groups of research and management staff working in the government-supported research institutes are shown different in their cognitive styles on R&D management. Identifying the differences and understanding the reasons why such differences exist are th prerequisites for working out an effective R&D management. The investigation was made with emphasis on the cognitive styles regarding the core elements of R&D managements such as R&D process, manpower, budget and information required for R&D activities. The cognitive styles on R&D management shown distinct between the two groups suggest in turn that narrowing down the diference could provide the way to more effective R&D management.

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A Study of Elucidation of Protein Quality of Raw and Heated Legumes Fed by Three Different Dietary Levels on Rats (팥과 녹두단백질의 첨가수준과 가열처리가 흰쥐의 성장에 미치는 영향)

  • 최경순
    • Journal of the Korean Home Economics Association
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    • v.20 no.4
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    • pp.91-98
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    • 1982
  • Various kinds of legumes have included as essential foods in Korean diet. However, a little attention have been paid on variety of those beans other than soybean. Main purposes of this study is to evaluate the protein quality of raw and cooked, red mung bean. Eighty male, sprague-Dawely rats weighing 50 gram were devided into 16 groups, five rats each. Casein protein from red and mung bean were used was included to after true digestibility of the protein of legemes. After 4 weeks feeding period animals were sacrificed and following data: all determined food intake, body weight gain, F.E.R., pp.E.R. and weights of liver, kidney heart, spleen, testis, pancreas, skeletal muscles. Food intake, body weight gain, F.E.R., pp.E.R. of casein group were higher than those of experimental groups (red bean, mung bean) body weight gain was increased with protein increment in the diet in all groups. The weight of liver showed significant difference between standard group and experimental group. (red bean, mung bean) The nitro gen content of liver and muscles were increased with level of protein in the diets.

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Personality Trait in Panic Disorder Patient and Its Clinical Significance (공황장애 환자의 성격특성과 임상적 의의)

  • Chae, Young-Lae;Lee, Chung-Tai;Kim, Bo-Yeon;Lee, Sung-Pil;Hong, Seung-Chul;Kim, Chong-Woo;Keh, Yoon-Jung
    • Korean Journal of Psychosomatic Medicine
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    • v.3 no.2
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    • pp.139-146
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    • 1995
  • Forty patients meeting DSM-III-H criteria for panic disorder and 51 normal controls were assessed with the Personality Diagnostic Questionnaire-Revised(PDQ-R), a self-rating scale designed to assess Axis II personality disorders and traits. Results replicated previous findings of a preponderance of dependent, avoidant, and histrionic features. But our result showed other features such as paranoid, schizotypal, borderline, and antisocial traits also. Patients were divided into two groups according to the severity of their personality traits(high or low). These groups were compared in various panic symptomatology and SCL-90-R. None of the specific symptom dimensions in panic disorder, i.e. panic, anxiety, agoraphobia, social impairment, or chronicity was different between groups. Rather, high personality trait groups were found to have significantly more symptomatology in SCR-90-R than low personality groups. Result indicated that patients exhibiting a greater number of personality traits were also significantly more symptomatic. The results suggested a possible link beteween panic disorder and personality disorder. And, general factors such as depression, social or interpersonal sensitivity might provide a much better explanation of personality disorders in panic patients.

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Three Intraspecific groups in Korean Isolates of Phytophthora drechsleri Based on PCR-RFLP of Ribosomal DNA (Ribosomal DNA의 PCR-RFLP에 의한 국내산 Phytophthora drechsleri의 3가지 종내그룹)

  • 홍승범;지형진;이승임;고승주;류진창;김인수
    • Korean Journal Plant Pathology
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    • v.14 no.5
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    • pp.519-525
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    • 1998
  • Intraspecific genetic diversity of Korean isolates of Phytophthora drechsleri was investigated based on PCR-RFLP of rDNA along with closely related species in the genus; P. cryptogea, P. melonis, P. erythroseptica, P. cinnamomi, P. cambivora and P. cactorum. Gene regions of nuclear small subunit and internal transcribed spacer (ITS) in rDNA were amplified with polymerase chain reaction and digested with 9 restriction enzymes. Phytophthora species was readily differentiated from each other based on the digestion patterns, however, P. cryptogea was not separable from some isolates of P. drechsleri. Twenty one isolates of P. drechsleri originated from 15 host plants were divided into three distinct groups designated as PdG1, PdG2 and PdG3, respectively. Four isolates in PdG1 were originated from green vegetables and tomato and nine isolates in PdG2 were mainly isolated from medicinal plants. The two groups showed 95.3% homology and four isolates of P. cyptogea came under the groups. However, Eight isolates in PdG3 collected from cucurbits were clearly differentiated from those of PdG1 and PdG2 by 66.5% homology, but completely matched with a Taiwan isolate of P. melonis. Results indicated that three distinct groups exist in Korean isolates of P. drechleri and each group has host preference. In addition, reclassification of the cucurbits isolates are reserved because of their distinct genetic characters from other intraspecific groups in P. drechsleri.

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Effect of Maternal Under-nutrition during Late Pregnancy on Lamb Birth Weight

  • Gao, F.;Hou, X.Z.;Liu, Y.C.;Wu, S.Q.;Ao, C.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.3
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    • pp.371-375
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    • 2008
  • This study investigated the effects of maternal undernutrition during late pregnancy on lamb birth weight. 45 Mongolian ewes, synchronized for oestrus and then mated, were divided into four groups and offered 0.86 MJME/kgw-0.75d-1 (control group; CG : ad libitum access to feed), $0.44MJME/kgw^{-0.75}d^{-1}$ (Restricted Group 3; R3), $0.33MJME/kgw^{-0.75}d^{-1}$ (Restricted Group 2; R2) and $0.20MJME/kgw^{-0.75}d^{-1}$ (Restricted Group 1; R1) respectively during late pregnancy (90-150 days). During restriction, maternal net body weight loss, insulin and NEFA concentrations and lamb birth weight were measured. The results indicated that loss of maternal body weight in R3, R2 and R1 was 4.42, 7.23, 11.13 kg respectively, which was significantly (p<0.01) higher than that in CG (0.93 kg). Insulin concentrations of the ewes in R1, R2 and R3 were lower and were significantly different (p<0.05) between restricted groups and CG at 124 d of pregnancy. NEFA concentrations in all groups tended to decrease from 90d of gestation to parturition and in R1 were significantly (p<0.05) lower than in CG at 124 d of gestation. Lamb birth weight in R1 was significantly lower than in R2, R3 and CG (p<0.05). In conclusion, with decreasing supply of maternal nutrition, the retardation of fetal growth became worse. When the plane of nutrition was below $0.33MJME/kgw^{-0.75}d^{-1}$, significant effects of maternal undernutrition on lamb birth weight were observed.

제 3세대 백금착체 항암제 신약개발 2. Antitumor activity and ex vivo pharmacodynamics of SKI 2053R

  • 박재갑;홍원선;방영주;조용백;태주호;김훈택;김대기;김기협;김노경
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1993.04a
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    • pp.74-74
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    • 1993
  • The in vitro cytotoxicity of SKI 2053R was evaluated against human tumor cell lines along with those of cisplatin and carboplatin using MTT assay. The cell lines tested were two human lung cancer cell lines and five human stomach cancer celt lines. The level of cytotoxic effects of SKI 2053R against two human lung cancer cell lines was located between cisplatin and carboplatin. However, the cytotoxic activity of SKI 2053R against five human stomach cancer cell lines was similar to that of cisplatin. SKI 2053R is considered to be selectively cytotoxic toward human stomach cancer cell lines. We carried out pharmacokinetic and ex vivo phrmacodynamic studies of SKI 2053R in beagle dogs to predict the clinical antitumor effect of SKI2053R, comparing with those of cisplatin and carboplatin. In ex vivo pharmacodynamics which used MTT assay as bioassay on the 2 lung and 5 stomach cancer cell, mean antitumor indexes (ATIs) of SKI 2053R were highest among three compounds in both lung and stomach cancer cell lines, especially in stomach cancer cell. Much higher ATI profile and maximal inhibition rates of SKI 2053R appeared in the stomach cancer cells will give desirable advantages to clinical trial s against gastric carcinoma. The anti tumor activity and target organ toxicity of SKI 2053R were compared with those of cisplatin on stomach cancer cell line, KATO III xenografted into nude BALB/c(nu/nu) mice. All groups of cisplatin and SKI 2053R showed active tumor regression. The inhibition rates(IR) of SKI 2053R were higher than that of cisplatin on the basis of mean IR. Though the loss of body weight was observed in all groups from the first week, the SKI 2053R group recovered it soon from the third week after the initiation of treatment, maintaining the most active anti tumor activity among three groups.

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AN EXPERIMENTAL STUDY OF THE EFFECTS OF DENTIN ADHESIVES ON MARGINAL ADAPTATION OF LIGHT CURED COMPOSITE RESIN (상아질 접착제의 사용에 의한 광중합성 복합레진의 변연접합도에 관한 실험적 연구)

  • Park, Seong-Ho;Lee, Chung-Suck;Park, Dong-Soo;Lee, Chan-Youg;Lee, Seung-Jong
    • Restorative Dentistry and Endodontics
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    • v.15 no.1
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    • pp.141-152
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    • 1990
  • The purpose of this study was to evaluate the effects of dentin adhesives(Gluma$^{(R)}$ and Scotchbond 2$^{(R)}$) on the marginal adaptation of light cured composite resin (Heliosit$^{(R)}$) by using SEM. The recently extracted 30 teeth were used and round cavities were prepared on the occlusal surfaces of the teeth with predesigned depth and diameter. The teeth were divided into three groups. Group 1 : Gluma$^{(R)}$ + Heliosit$^{(R)}$ Group 2 : Scotchbond 2$^{(R)}$ + Heliosit$^{(R)}$ Group 3 : Enamelbond$^{(R)}$ + Heliosit$^{(R)}$ Filling with Heliosit, the teeth were stored in saline solution for 24 hours. After the thermocycling procedure, the teeth were cut vertically into the restorations. The SEM observation was carried out to evaluate the marginal adaptation of the composite resin. The following results were obtained. The following results were obtained. 1. The groups using Gluma$^{(R)}$ and Scotchbond 2$^{(R)}$ showed better than the control group on marginal adaptation to the dentin. 2. The group using Gluma$^{(R)}$ was superior to the group using Scotchbond 2$^{(R)}$, but the difference was not significant. 3. In all groups, the marginal gaps were wider on the pulpal walls than on the lateral walls of restorations.

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