• Title/Summary/Keyword: R-Peak

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Tetramine Analysis using Liquid Chromatography-Tandem Mass Spectrometry and Ion Chromatography (LC-MS/MS와 Ion Chromatography를 이용한 테트라민 분석)

  • Song, Ki-Cheol;Lee, Ka-Jeong;Kim, Ji-Hoe;Yoon, Ho-Dong;Yu, Hong-Sik;Mok, Jong-Soo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.44 no.1
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    • pp.45-49
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    • 2011
  • As a first step toward identifying a new method for testing sea snail tissue for toxins, and thus prevent food poisoning due to the ingestion of contaminated snails, we measured the tetramine [$(CH_3)_4N^+$] contents of sea snails from the Korean coast using both liquid chromatography-tandem mass spectrometry (LC-MS/MS) and ion chromatography. For tetramine tested, good linearity ($r^2$ = 0.9996) was observed between the amounts in the injected samples and the peak areas of standard toxins, which ranged from 0.1 to 100 ng. The recovery (%) of tetramine from spiked tissue and mid-gut gland samples ranged from 84.0 to 95.3%. The quantitative results for tetramine using this method were in good agreement with the theoretical values. LC-MS/MS has both high sensitivity and selectivity, which makes it possible to measure trace quantities of tetramine in samples.

Maturity and Spawning of Pacific Sand Eels Ammodytes japonicus in Coastal Waters near Donghae, Gangwon-do (강원도 동해시 연안에 서식하는 까나리(Ammodytes japonicus)의 성숙과 산란)

  • Kim, So Ra;Kim, Jong Bin;Lee, Soo Jeong;Yang, Jae Hyeong
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.53 no.1
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    • pp.19-26
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    • 2020
  • The maturity and spawning of pacific sand eels Ammodytes japonicus, was investigated using samples collected by gill net in coastal waters near Donghae, Gangwon-do, from January 2017 to December 2018. Monthly changes were analyzed in maturity stage, gonadosomatic index (GSI), egg diameter, fecundity (F), and total length (TL) at 50% group maturity. The average TLs of female and male A. japonicus were 18.5 and 18.1 cm, respectively. The spawning period was from November to March, with the peak from December to February based on monthly changes in GSI and maturity stages. The egg diameter during the spawning-capable stage was 300-1000 (main mode 500-600) ㎛. Fecundity ranged from 6,411 eggs at 16.7 cm fork length to 45,771 eggs at 24.7 cm fork length. The relationship between TL and F was F=0.00005TL4.2715 (R2=0.7216), such that F increased with TL. TL at 50% group maturity was estimated to be 15.1 cm for both sexes.

Maturation and Spawning of the Red Seabream Pagrus major in the South Sea of Korea (한국 남해에 출현하는 참돔(Pagrus major)의 성숙과 산란)

  • Jin, Suyeon;Im, Yang Jae;Choi, Jung Hwa;Jeong, Jae Mook;Nam, Ki Mun;Kim, Do-Gyun;Choi, Yu Jeong;Baeck, Gun Wook
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.53 no.1
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    • pp.43-49
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    • 2020
  • The maturation and spawning of red seabream Pagrus major were investigated using 1,014 samples collected monthly from January to December of 2018, in the South Sea of Korea. Based on monthly changes in maturity stage and gonadosomatic index, the spawning period was estimated to be between April and August, with peak spawning occuring from May to June. Fecundity varied between 228,996 and 4,544,948 eggs. The relationship between fecundity (F) and fork length (FL) in this species can be expressed by the equation F=0.4869FL3.9452 (R2=0.7448). Using a logistic function, the percentage of sexually mature females was estimated to be over 50% for fish with a FL of 35.3 cm.

Relationships between Milk Yield, Post-Partum Body Weight and Reproductive Performance in Friesian × Bunaji Cattle

  • Oni, O.O.;Adeyinka, I.A.;Afolayan, R.A.;Nwagu, B.I.;Malau-Aduli, A.E.O.;Alawa, C.B.I.;Lamidi, O.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.11
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    • pp.1516-1519
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    • 2001
  • The data consisted of 369 lactation records for calvings over a sixteen-year period (1972-1987) and included only cows that had normal milk records. The data were analysed using a linear model containing the fixed effects of parity, year of calving and season of calving. The least squares means${\pm}$S.E. were $1,273{\pm}58.4kg$ for milk yield, and for post-partum body weight (kg) at 2, 3 and 4 months after calving were $343.40{\pm}3.96$, $346.10{\pm}4.10$ and $352.54{\pm}4.26$, respectively. With the exception of season of calving, the effects of parity and year of calving were significant (p<0.01) on the performance of the animals. Thus, the mean-milk yields 1162, 1351 and 1350, were similar for pre-, peak- and post rainy seasons, respectively. On the other hand, as parity increased from 1 to 3, milk yield also increased, but thereafter, there was a gradual decline in milk yield. Similarly, post-partum body weight also increased with parity. However, no consistent pattern for year effect was observed which probably was a reflection of the variation in climatic conditions, or forage quality and/or availability. The phenotypic correlations between milk yield and post-partum body weights were negative and small (ranging from -0.01 to -0.08). However, high milk production in cows was associated with longer calving interval. The implications from the phenotypic correlations are suggestive of one or two possibilities. Firstly, selection for increased body weight may actually result in decreased milk yield. Also, a substantial genetic antagonism may exist between milk yield and fertility in the crossbred cows. Therefore, it is important that selection to improve milk production should take into consideration the reproductive performance of the cows.

An Experimental Assessment of the Effects of Residual Stresses on Fracture Behavior of the Plate (압축잔류응력이 판의 파괴 특성에 미치는 영향에 관한 실험적 평가)

  • Jang, Chang-Doo;Park, Yong-Kwan;Song, Ha-Cheol;Kim, Byung-Il
    • Journal of Navigation and Port Research
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    • v.26 no.4
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    • pp.435-440
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    • 2002
  • The quantitative assessment of the effect of the residual stress on fracture behavior was executed by some experiment and numerical analysis. First of all, artificial residual stresses were imposed on CT(Compact Tension) specimens by local heating using gas torch, and an appropriate distribution of residual stresses was obtained by thermal elastic-plastic FE analysis. To certify the result of the FE analysis, an experimental measurement was performed in accordance with ASTM standard. Fracture toughness test was executed on the several types of specimens. The first type was the specimen without residual stresses, and the others had different peak value of compressive residual stress at crack front via controlling the heat flux. All the test results were presented on th J resistance(JR) curves and discussed to verify the effect of compressive residual stresses on fracture behavior.

A Study on Magnetic State of Nonstoichiometric Substituted Ferrite Fe$_{}1.429$(Al$_{4-x}$ Ga$_{x}$)$_{0.286}$ Si$_{0.143}$ /O$_4$ Systme. (비화학량론적 치환형 페라이트 Fe$_{}1.429$(Al$_{4-x}$ Ga$_{x}$)$_{0.286}$ Si$_{0.143}$ /O$_4$계의 자기적 상태 연구)

  • Choi, Seung-Han
    • Korean Journal of Materials Research
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    • v.5 no.7
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    • pp.808-815
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    • 1995
  • The magnetic states of nonstoichiometric substituted ferrite Fe$_{}1.429$(Al$_{4-x}$ Ga$_{x}$)$_{0.286}$ Si$_{0.143}$ /O$_4$ system have been investigated using Mossbauer spectroscopy and SQUID. The Mossbauer spectra at room temperature show well-defined two Zeeman patterns for x=0.2, superpositions of two Zeeman patterns and a doublet for x=0.4. The doublet peak seems to be originated from the superparamagnetic clusters. The system shows significant departures from the Neel's collinear model and seems to be the diluted ferrites. The Mossbauer spectra below R.T show various and complicated patterns, which can be explained by freezing of the superparamagnetic clusters. On cooling, magnetic states of the system may be various and multicritical, Resulting from SQUID measurements, there was an unexpected dip in magnetization curves below 50K. It was interpreted as an effect of spin canting including spin freezing or collective spin behavior.

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Progress In Commercialization Of Light Emitting Polymers: Dow Polyfluorenes

  • Wu, W.;Inbasekaran, M.;Hudack, M.;Welsh, D.;Yu, W.;Chen, Y.;Wang, C.;Kram, S.;Tacey, M.;Bernius, M.;Fletcher, R.;Kiszka, K.;Munger, S.;O'Brien, J.;Hills, M.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2002.08a
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    • pp.340-343
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    • 2002
  • We report here our recent progress in the development and commercialization of polyfluorenes emitting red, green and blue (ROB) colors as materials for light emitting diodes (LEDs). Our patented version of the Suzuki coupling process has been used to synthesize a variety of fluorenebased homopolymers and copolymers emitting colors across the entire visible spectrum. The optical and electronic properties of the polymers are tailored through selective incorporation of different aromatic units into the polyfluorene backbone. Our latest green emitter, reported herein, provides very efficient devices with a low turn-on voltage of 2.25 V, a peak efficiency of 10.5 Cd/A at 6,600 Cd/$m^2$ at 4.85 V. These devices maintain an efficiency of greater than 10 Cd/A up to 50,000 Cd/$m^2$ and demonstrate very good stability as exemplified by a device half-life of greater than 1,500 hours starting from 1,100 Cd/$m^2$. Considerable progress has also been made with red and blue emitters and will be the subject of this presentation.

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Development of Chair Backrest for Non-intrusive Simultaneous Measurement of ECG and BCG (심전도와 심탄도의 무구속적 동시 측정을 위한 의자 등받이 개발)

  • Lim, Yong-Gyu
    • Journal of the Institute of Convergence Signal Processing
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    • v.19 no.3
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    • pp.104-109
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    • 2018
  • A non-intrusive ECG and BCG measurement system is introduced. The system is built on a auxiliary backrest of a chair. The developed system is aimed to non-intrusive assessment of cardiovascular dynamic indices such as pulse arrival time(PAT) and pre-ejection period (PEP). In the system, capacitive active electrodes and capacitive grounding were used for the non-intrusive indirect-contact ECG measurement, and EMFi pressure sensor was used for the non-intrusive BCG measurement. The capacitive active electrodes and the EMFi sensor were attached on the backrest. Using the system, ECG and BCG were successfully acquired. The measured BCG showed peaks that following ECG R peaks. It was shown that the time interval between Q wave in ECG and first peak in BCG correlates Pre-ejection period measured by impedance-cardiogram. The results showed that the introduced system can be used for the non-intrusive various cardiovascular information including ECG, PAT, PEP.

Effects of Baicalein on the Bioavailability of Nicardipine in Rats

  • Son, Hong-Mook;Choi, Jun-Shik
    • Journal of Pharmaceutical Investigation
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    • v.40 no.5
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    • pp.291-296
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    • 2010
  • This study was to investigate the effect of baicalein, an antioxidant, on the bioavailability of nicardipine after orally or intravenously administered nicardipine in rats. Nicardipine was administered orally (12 mg/kg) or intravenously (4 mg/kg) with or without orally administered baicalein (0.4, 2 or 10 mg/kg) to rats. In the inhibitory effect of baicalein on CYP3A4 activity, baicalein inhibited CYP3A4 activity with $IC_{50}$ values of 9.2 ${\mu}M$. The cell-based P-gp activity test using rhodamine-123 also showed that baicalein (30-10 ${\mu}M$, p<0.01) significantly inhibited P-gp activity. Compared with the control group (given nicardipine alone), the area under the plasma concentration-time curve (AUC) was significantly (2 mg/kg, P<0.05; 10 mg/kg, P<0.01) increased by 25.9-60.0%, and the peak concentration ($C_{max}$) was significantly (10 mg/kg, P<0.01) increased by 40.0% in the presence of baicalein after orally administration of nicardipine. Consequently, the relative bioavailability (R.B.) of nicardipine was increased by 1.26- to 1.60-fold and the absolute bioavailability (A.B.) was significantly (2 mg/kg, P<0.05; 10 mg/kg, P<0.01) increased by 26.0-59.9%. Compared to the i.v. control, baicalein did not significantly change pharmacokinetic parameters of nicardipine in i.v. administration. Accordingly, the enhanced oral bioavailability of nicardipine might be mainly due to increased intestinal absorption caused by P-gp inhibition rather than to reduced elimination of nicardipine by baicalein. The increase in the oral bioavailability might be mainly attributed to enhanced absorption in the small intestine via the inhibition of P-gp and reduced first-pass metabolism of nicardipine via the inhibition of the CYP3A subfamily in the small intestine and/or in the liver by baicalein. Based on these results, nicardipine dosage should be adjusted when given concomitantly with baicalein.

Respiratory Effort Monitoring Using Pulse Transit Time in Human (인체에서 맥파전달시간을 이용한 호흡노력 모니터링)

  • 정동근
    • Journal of Biomedical Engineering Research
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    • v.23 no.6
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    • pp.485-489
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    • 2002
  • In this study. respiratory efforts were monitored by the change of pulse transit time (PTT) which is related with the arterial pressure PTT is the time interval between the peak of R wave in ECG and the maximal slope point of photoplethysmogram(PPG). Biosignals, ECG and finger photoplethysmogram(PPG), were converted to digital data, and PTT was evaluated in personal computer with every heart beat. Results were presented as a graph using spline interpolation. The software was implemented in C$\^$++/ as a window-based application program. PTT was periodically changed according to airflow in resting respiration. In the resting respiration, PTT was changed according to the respiratory cycle. The amplitude of PTT fluctuation was increased by deep respiration, and increased by partial airway obstruction. These results suggest that PTT is responsible to respiratory effort which could be evaluated by the pattern of PTT change. And it is expected that PTT could be applied in the monitoring of respiratory effort by noninvasive methods, and is very useful method for the evaluation of respiratory distress.