• Journal of Nutrition and Health
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• v.33 no.3
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• pp.250-256
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• 2000

Hyperhomocysteinemia has been shown to be associated with increased risks for macrovascular angiopathy. The present study was conducted to document the relationship between plasma homocysteine levels and the presence of macrovascular angiopath in patients with Type II diabetes mellitus. Plasma total homocysteine was determined by a HPLC-fluorescence detection method in a total of 238 subjects, 127 diabetic patients and 111 control. Dietary information including folate intake was assessed by a 24-hour recall in a total 113 subjects, 70 diabetic patients and 43 control. Folate intake was significantly lower inn patients with diabetes mellitus than that in the control. The lowered folate intake in the diabetic patients was mainly due to reduced intakes of fruits and vegetables. The average plasma homocysteine level of patients with MA was 14.2$\mu$㏖/L, which was significantly higher than that of either the patients without MA(11.4$\mu$㏖/L) or the control(11.5$\mu$㏖/L). Twenty five percent of the diabetic patients were positively correlated with age (r=0.20), body weight (r=0.28), body mass index (r=0.28), body mass index (r=0.18), diastolic blood pressure (r=0.20), and total cholesterol (r=0.14). cigarette smokers had significantly higher levels of plasma homocysteine than the non-smokers. Further prospective studies are needed to investigate whether folate or other B vitamin supplementation could be beneficial for the prevention of hyperhomocysteinemia or macrovascular angiopathy in the diabetic patients.

• KSTLE International Journal
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• v.1 no.2
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• pp.113-117
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• 2000

The rotary-vane compressor has become one of the most successful types of compressors because of its mechanical reliability, compactness, and adaptability to moderately high-speed operation in virtually an unlimited range of sizes. However recently, the depletion of the ozone layer due to the current refrigerant(R22) has been getting worse, and it is one of the world's pressing issues. In this paper, we will discuss the use of R410a in the compressor of a room air-conditioner as an alternative refrigerant and air-conditioning system to R22, since R410a has greater refrigerant characteristics than R22. Miniaturization of the rotary compressor for the new refrigerant and air-conditioning system is also possible, which reduces the prime cost of production, hence R410a is naturally a better refrigerant. But to apply the new HFC refrigerant system in refrigeration and air-conditioning systems, a significant redesign of the current refrigerant system is also required, because as the refrigeration changes, lubrication characteristics vary. Close attention must be paid to friction force and energy loss due to friction and wear at many sliding areas.

• Molecules and Cells
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• v.22 no.1
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• pp.113-118
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• 2006

Thioredoxin reductase (TrxR), a component of the redox control system involving thioredoxin (Trx), is implicated in defense against oxidative stress, control of cell growth and proliferation, and regulation of apoptosis. In the present study a stable transfectant was made by introducing the vector pcDNA3.0 harboring the fission yeast TrxR gene into COS-7 African green monkey kidney fibroblast cells. The exogenous TrxR gene led to an increase in TrxR activity of up to 3.2-fold but did not affect glutathione (GSH) content, or glutaredoxin and caspase-3 activities. Levels of reactive oxygen species (ROS), but not those of nitric oxide (NO), were reduced. Conversely, 1-chloro-2,4-dinitrobezene (CDNB), an irreversible inhibitor of mammalian TrxR, enhanced ROS levels in the COS-7 cells. After treatment with hydrogen peroxide, the level of intracellular ROS was lower in the transfectants than in the vector control cells. These results confirm that TrxR is a crucial determinant of the level of cellular ROS during oxidative stress as well as in the normal state.

• Korean Journal of Microbiology
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• v.24 no.2
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• pp.113-118
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• 1986

Optimum temperature and pH of glutamine synthetase activity (E.C. 3.6.1.2.) of R. sphaeroides D-230 was $35^{\circ}C$ and 6.8, respectively. The adenylated state of GS in R. sphaeroides D-230 was stabilized by addition of 0.2mg/ml of cethyltrimethylammoniumbromide. Valine, histidine, proline, isoleucine, and lysine were good nitrogen source for the growth of R. sphaeroides D-230. The growth of R. sphaeroides D-230 in $N_2,\;NaNO_3\;or\;NH_4Cl$ as sole nitrogen source was lower than in any otherculture conditions. GS activity was inhibited, more or less, by various amino acid. THe relative inhibition rate of the enzyme by added 7mM arginine, $NH_4Cl,\;N_2,\;and\;NaNO_3$ was 63.8%, 26.79%, 6.24%, and 10.64%, drespectively. THe hydrogen evolution of R. sphaeroides D-230 grown in N-limited media was inhibited by 0.1mM MSX, irreversible GS inhibitor. GS activity was completely inhibited by 1.0mM MSX but ammonia released maximally at the same concentration of MSX. Ammonia release by added MSX was increased up to 1.0mM MS, but decreased above 1.0mM MSX. It is probably due to inhibition of nitrogenase actixity by MSX. Nitrogenase activity was not inhibited at low concentration of MSX. These results suggests that the inhibition of nitrogenase activity by ammonia is mediated by products of ammonia assimilation rather than by ammonia itself.

• Proceedings of the IEEK Conference
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• 2002.07a
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• pp.113-116
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• 2002

In this paper dynamic characteristics were investigated of the perception of a bound image width. Subjective evaluation tests were carried out of the width of a sound image when its presentation region was moved in the horizontal plane. As a result, the sound image width was perceived narrower or wider than the actual presentation region when the sound source width was decreased or increased, respectively. The result obtained shows that a phenomenon which is a kind of auditory motion aftereffects was occurred in the perception of a sound source with changing its width.

• Journal of the Korean Society of Food Science and Nutrition
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• v.30 no.3
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• pp.466-470
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• 2001

Response surface methodology was used for monitoring extraction conditions, based on quality properties of old pumpkin extracts. Hunter's color L value of extracts was maximized at 101℃, 2.6 hr and decreased gradually after maximum point. The polynomial equation for Hunter's color L value showed 10% of significance level and 0.8799 of R². Hunter's color a value was minimized at 117℃, 3.9 hr and R² of polynomial equation was 0.9852 within 1% significance level. Hunter's color b value and ΔE value increased as the extracting temperature and time increased. Extraction yield of old pumpkin was maximized at 110℃, 4 hr and increased in proportional to the extracting temperature and time, but decreased after 113℃ and 2 hr. Viscosity of pumpkin extracts were maximized at 120℃, nearly 3 hr. R² of polynomial equations for yield, viscosity and sugar content were 0.9532, 0.9812 and 0.8869, respectively. Optimum ranges of extraction conditions for quality properties of old pumpkin were 102∼109℃, 2.5∼3.5 hr, respectively. Predicted values at the optimum extraction condition agreed with experimental values.

• Proceedings of the SAREK Conference
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• 2008.11a
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• pp.113-118
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• 2008

For a R134a rotary vane compressor used for car air conditioners, characteristics of gas compression and oil supply have been studied. The compressor model under investigation has the low volume ratio of suction to discharge volumes so that there occur flow reversal from discharge port to compression chamber as the leading vane passes over the discharge port. As a result, the volumetric and adiabatic efficiencies turn out to be relatively low compared to other types of displacement compressors. Oil supply mechanism has been comprehended for mathematical modeling and oil flow rate has been calculated for the individual oil passages. This study on the gas compression and oil supply of a rotary vane compressor can be applied to a future design practice on a similar type of compressor.

• Bulletin of the Korean Chemical Society
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• v.19 no.3
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• pp.340-344
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• 1998

A facile synthesis of 4,5-(1',2'-diphenylethylenedithio)-1,3-dithiole-2-thione (dPhEDT-DTT) is carried out via a Diels-Alder type [2+4] cycloaddition reaction of 1,3-dithiol-2,4,5-trithione oligomer and t-stilbene. Molecular structure of dPhEDT-DTT is determined by x-ray crystallography: space group P1, a=11.694(3) Å, b=12.117(3) Å, c=14.688(3) Å, α=113.12(2)°, β=102.23(2)°, γ=107.02(2)°, V= 1699.1(7) Å3, Z=2. It turns out that dPhEDT-DTT crystallizes as a racemic compound consisting of (R,R) and (S,S) enantiomers. Coupling reaction of dPhEDT-DTO undergone in neat P(OEt)3 yields TTF(SEt)4 instead of ET derivative. When PR3 (R=OEt, OPh, Ph) is used in benzene, toluene or xylene, however, dPhEDT-DTO is decomposed.

• Journal of Technology Innovation
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• v.24 no.2
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• pp.91-113
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• 2016

The purpose of this study is to examine the causal relationship among R&D spending and variables of technology trade, and to explore promoting R&D activities and revitalizing technology trade. To analyze the causal relationship, we built a multivariate model that consists of government R&D spending, private R&D spending, technical importation and export of techniques, and employed the Granger-causality test based on an error correction model. The results show that there are five Granger-causality relationship among them in the short run, as well as there are eleven Granger-causality relationship among a total of twelve causal relationship, excluding only a unidirectional causality relationship from the government R&D spending to the export of techniques, in the long run. Besides, we attempted the impulse-response analysis on them to observe the reaction of any dynamic system in response to some external change. The significance of this paper is to make sure the causal relationship between R&D investments and the technology trade by analyzing empirically, and to suggest several implications for promoting the R&D activities and revitalizing the technology trade.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.9 no.2
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• pp.201-212
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• 2002

Purpose: The purpose of this study was to identify the association between Sasang constitution and type A/B personality. Method: The subjects for this study were 113 Korean adults living in Kangwon Province, the northeastern part of Korea. The data were collected from March 10 to April 13. 2002 using a structured questionnaire. The instrument for this study were QCSSII (Questionnaire for Sasang Constitution Clsssification II) by Kim et al.(1996), and the Revised Type A/B personality by Eysenck & Fulker(1983). The data were analyzed through the SPSS 10.0 for Windows program using frequency, percentage, $x^2$-test, ANOVA, and Pearson correlation coefficient. Results: The results of the study are as follows : 1. Of 113 Korean adults, the portion who were Taieum-in, Soeum-in, Soyang-in was 39.8%, 34.5%, 25.7% respectively. 2. For type A/B personality, mixed type was most common, 19.4% of the participants were of type B and 8.0%., type A. 3. For type A/B behavior, mixed type was most common at 47.8% and type A was 2.7%. 4. There were statistically significant differences in the Sasang constitutional type according to BMI (F=14.542, P<.001), and alcohol consumption (F=4.256, p<.018). 5. There were significant difference between type A/B Personality and BMI (F=3.592, P<.032). 6. The data shows correlations between BMI and amount smoked per day (r=2.74, P<.004), between BMI and alcohol consumption (r=-.303, p<.008), between BMI and Sasang constitutional type (r= -.592, p<.0001), between BMI and type A/B personality (r=285, p<.011), between amount smoked per day and alcohol consumption (r= .-361, p<.001). between alcohol consumption and Sasang constitutional type (r=-.306, p<.019). between perceived health state and type A/A personality (r= .246, p<.011). Conclusion: According to the above findings, it can be concluded that further research is need to understand the Sasang constitution for the discipline of Nursing and for nurses to prepare nursing protocols relevant to Sasang constitutional care. Also, Sasang constitution has to be considered in research and practice in the health care delivery system.