• Toxicological Research
• /
• v.17
• /
• pp.227-236
• /
• 2001

The IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans has reviewed, summarized and evaluated 869 environmental agents and exposures as oj June 2000. This large collection includes all relevant published epidemiological data on cancer in exposed humans and results of bioassays for carcinogenicity in experimental animals. Since 1986. cancer data have been systematically supplemented by summaries of other toxicological data that are relevant to assessments of carcinogenic hazard. These include summaries qf genetic and related effects of chemicals. which have been prepared as Genetic Activity Profiles (GAP) by the U.S. EPA in collaboration with IARC. As the Mono-graphs have proved increasingly valuable and influential worldwide. they have evolved into an encyclopedia on environmental carcinogenic risks to humans. However. the Monographs have historically been prepared only as printed books with limited distribution. and the Monographs Programme has needed to adjust to expectations oj wider availability. Since 1998 the evaluations and summaries have been globally accessible by Internet from IARC (http://www.iarc.fr) and the GAP profiles by Internet from EPA (http://www.epa.gov/gapdb/). with the two web sites linked. Improved EPN/ARC GAP database and software. GAP2000. now link GAP profiles directly to the appropriate IARC web pages for summaries of evaluations of a given compound and its overall IARC classification. During the year 2000. by means of optical character recognition (OCR) technology the entire series of IARC Monographs is being converted to an electronic version. The first edition is now available commercially in CD-ROM format and will soon become available on-line at .

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.56 no.4
• /
• pp.329-341
• /
• 2011

The objective of this study was to determine the genetic diversities of major rice blast resistance genes among 84 accessions of aromatic rice germplasm. Eighty four accessions were characterized by a dominant 11 set of PCR-based SNP and CAPS marker, which showed the broad spectrum resistance and closest linkage to seven major rice blast resistance (R) genes, Pia, Pib, Pii, Pi5 (Pi3), Pita (Pita-2), and Pi9 (t). The allele specific PCR markers assay genotype of SCAR and STS markers was applied to estimate the presence or absence of PCR amplicons detected with a pair of PCR markers. One indica accession, Basmati (IT211194), showed the positive amplicons of five major rice blast resistance genes, Pia, Pi5 (Pi3), Pib, Pi-ta (Pi-ta2), and Pik-5 (Pish). Among 48 accessions of the PCR amplicons detected with yca72 marker, only five accessions were identified to Pia gene on chromosome 11. The Pib gene was estimated with the NSb marker and was detected in 65 of 84 accessions. This study showed that nine of 84 accessions contained the Pii gene and owned Pi5 (Pi3) in 42 of 84 accessions by JJ817 and JJ113-T markers, which is coclosest with Pii on chromosome 9. Only six accessions were detected two alleles of the Pita or Pita-2 genes. Three of accessions were identified as the Pi9 (t) gene locus.

• Asian-Australasian Journal of Animal Sciences
• /
• v.27 no.9
• /
• pp.1263-1269
• /
• 2014

Comprehensive information on genetic diversity and introgression is desirable for the design of rational breed improvement and conservation programs. Despite the concerns regarding the genetic introgression of Western pig breeds into the gene pool of the Korean native pig (KNP), the level of this admixture has not yet been quantified. In the present study, we genotyped 93 animals, representing four Western pig breeds and KNP, using the porcine SNP 60K BeadChip to assess their genetic diversity and to estimate the level of admixture among the breeds. Expected heterozygosity was the lowest in Berkshire (0.31) and highest in Landrace (0.42). Population differentiation ($F_{ST}$) estimates were significantly different (p<0.000), accounting for 27% of the variability among the breeds. The evidence of inbreeding observed in KNP (0.029) and Yorkshire (0.031) may result in deficient heterozygosity. Principal components one (PC1) and two (PC2) explained approximately 35.06% and 25.20% of the variation, respectively, and placed KNP somewhat proximal to the Western pig breeds (Berkshire and Landrace). When K = 2, KNP shared a substantial proportion of ancestry with Western breeds. Similarly, when K = 3, over 86% of the KNP individuals were in the same cluster with Berkshire and Landrace. The linkage disquilbrium (LD) values at $r^2_{0.3}$, the physical distance at which LD decays below a threshold of 0.3, ranged from 72.40 kb in Landrace to 85.86 kb in Yorkshire. Based on our structure analysis, a substantial level of admixture between Western and Korean native pig breeds was observed.

• The Journal of the Korea Contents Association
• /
• v.7 no.9
• /
• pp.117-126
• /
• 2007

The purpose of this paper is to analyze the trends of technological development in the field of portable multimedia player (PMP) through patent information of major countries, and evaluate the technological Position of PMP. In the first place, we will carry out a quantitative analysis in terms of the annual trend of patent applications in the field of PMP, the technological position of PMP through portfolio analysis, the share of patents by applicant, the worldwide innovation leader of major countries, and the patent trend by IPC. Secondly, we will measure the technological level of PMP using indicators including cites per patent (CPP), science linkage (SL), and patent family size (PFS). Finally, we will evaluate the directions of research or technology development and the technological competitiveness of major countries. This evaluation could give us some useful policy implications on the strategy of R&D in PMP.

• Journal of Advanced Navigation Technology
• /
• v.24 no.2
• /
• pp.115-120
• /
• 2020

PS-LTE, which is mentioned as a next-generation disaster network technology, is a communication technology that supports communication between terminals and group communication necessary for public safety communication based on LTE technology. Currently, Korea is establishing a PS-LTE network construction plan and installing a PS-LTE system. The world is currently making a lot of efforts to build a disaster network system using PS-LTE. However, due to the characteristics of the closed network that only the related persons can access, it can not be operated like the existing commercial network, so it is necessary to build a new network. And it is expected that many periods and costs will be required. In order to establish a disaster safety communication network efficiently, it is necessary to consider the linkage of PS-LTE network, which is newly constructed by complementing the problems such as security and access priority to existing LTE network rather than unconditional new construction.

• The Journal of the Korea institute of electronic communication sciences
• /
• v.12 no.1
• /
• pp.129-138
• /
• 2017

The aim of this paper is to suggest methodology for local governments when discovering locally customized future promising industries with regard to policies of central government, regional competencies, and industrial promising. Firstly, key industries by region specified in '5-years regional industrial development master plan(2014)' were utilized. Secondly, science and technology competency by region was calculated with analyzing patent data in each key industries. Thirdly, industrial promising was verified by calculating Knowledge Stock and Activity Index based on measuring industry-IPC linkage. Based on the methodology proposed above, case study(case of Busan city) was done. Finally, 7 core industries and 94 candidates of future promising industries were extracted on the basis of 5 digit of KSIC subdivision. The methodology is expected to contribute local governments to establish evidence-based, efficient, and future-oriented local R&D roadmapping.

• Proceedings of the Korean Society of Crop Science Conference
• /
• 2017.06a
• /
• pp.146-146
• /
• 2017

The pod shattering or dehiscence is essential for the propagation of pod-bearing plant species in the wild, but it causes significant yield losses during harvest of domesticated crop plants. Identifying novel molecular makers, which are linked to seed-shattering genes, is needed to employ the molecular marker-assisted selection for efficiently developing shattering-resistant soybean varieties. In this study, a genetic linkage map was constructed using 115 recombinant inbred lines (RILs) developed from crosses between the pod shattering susceptible variety, Keunol, and resistant variety, Sinpaldal. A 180 K Axiom(R) SoyaSNPs data and pod shattering data from two environments in 2001 and 2015 were used to identify quantitative trait loci (QTL) for pod shattering. A major QTL was identified between two flanking single nucleotide polymorphism (SNP) markers, AX-90320801 and AX-90306327 on chromosome 16 with 1.3 cM interval, 857 kb of physical range. In sequence, genotype distribution analysis was conducted using extreme phenotype RILs. This could narrow down the QTL down to 153 kb on the physical map and was designated as qPDH1-KS with 6 annotated gene models. All exons within qPDH1-KS were sequenced and the 6 polymorphic SNPs affecting the amino acid sequence were identified. To develop universally available molecular markers, 38 Korean soybean cultivars were investigated by the association study using the 6 identified SNPs. Only two SNPswere strongly associated with the pod shattering. These two identified SNPs will help to identify the pod shattering responsible gene and to develop pod shattering-resistant soybean plants using marker-assisted selection.

• Proceedings of the Korean Society of Crop Science Conference
• /
• 2017.06a
• /
• pp.26-26
• /
• 2017

Seed germination stimulated by light is said to be photoblastism. Photoblastism has not been reported in cereal crops, especially in the rice, but Korean weedy rice was reported to have photoblastism and longer mesocotyl than cultivar. Photoblastic weedy rice (PBR) was used to identify QTLs for photoblastism and mesocotyl length. In previous works, QTLs for photoblastism, pbr1 and pbr12 were identified on chromosomes 1 and 12 using 124 F4 lines from a cross between Ilpum and PBR using bulked segregant analysis. Two QTLs for mesocotyl elongation, qMel-1 and qMel-3 were mapped on chromosomes 1 and 3 120 F8 lines from the same cross. Of interest, the RM8260-RM246 region of pbr1 overlapped with a region of qMel-1. To know whether these two QTLs are functionally related, 110 F3 lines were developed from a cross between Ilpum and CR7124. CR7124 having photoblastism and long mesocotyl was selected from 120 F8 lines. 95 F3 lines were measured for germination rate in a light and dark condition and mesocotyl length. Mesocotyl length and germination rate in the dark condition in F3 lines showed significant correlation (r = 0.7, P < 0.0001). 95 $F_3$ lines were genotyped with RM7419 on chromosome 1. ANOVA showed that RM7419 was tightly linked to QTLs for photoblastism as well as mesocotyl length on chromosome 1 (P < 0.0001) indicating the tight linkage of two QTLs. Fine mapping of the two QTL is underway to analyze their functional relationship.

• Proceedings of the Korean Society of Crop Science Conference
• /
• 2017.06a
• /
• pp.145-145
• /
• 2017

Foxglove aphid, Aulacorthum solani (Kaltenbach), is a Hemipteran insect that infected a wide variety of plants worldwide and caused serious yield losses in crops. The objective of this study was to identify the putative genes to foxglove aphid resistance in wild soybean, PI 366121 (Glycine soja Sieb. and Zucc.). One hundred and forty-one F4:8 recombinant inbred lines developed from a cross between susceptible variety, Williams 82 and foxglove aphid resistance wild soybean, PI 366121 were used. The two type of resistance response, antibiosis and antixenosis resistance were evaluated through choice and no-choice test, graded by the degree of total plant damage and primary infestation leaf damage; a genome-wide molecular linkage map was constructed with 29,898 single-nucleotide polymorphism markers utilizing a Axiom(R) 180K soyaSNP array. Using inclusive composite interval mapping analysis for foxglove aphid resistance, one major candidate QTL on chromosome 7 was identified. The major QTL on chromosome 7 showed both antixenosis and antibiosis resistance responses. The newly identified major QTL was consistent with previously reported QTL, Raso2, which showed around 5 times narrow down interval range with 8 candidate genes. Furthermore, total 1,115 soybean varieties including Glycine soja and Glycine max were exposed to germplasm screening, and 31 varieties, which showed significant antibiosis type foxglove aphid resistance were identified. This result could be useful in breeding for new foxglove aphid resistant soybean cultivars and developing novel insecticides.

• Journal of Electrical Engineering and Technology
• /
• v.11 no.3
• /
• pp.609-617
• /
• 2016

Belt-driven Starter Generator (BSG) differs from other mild hybrid systems as the crankshaft of vehicle are not run off. Motor permits a low-cost method of adding mild hybrid capabilities such as start-stop, power assist, and mild levels of regenerative braking. Wound rotor synchronous motor (WRSM) could be adopted in BSG system for HEV e-Assisted application instead of the interior permanent magnet synchronous motor (IPMSM). In practice, adequate torque is indispensable for starter assist system, and energy conversion should be taken into account for the HEV or EV as well. Particularly, flux weakening control is possible to realize by adjusting both direct axis components of current and field current in WRSM. Accordingly, this paper present an off-line current acquisition algorithm that can reasonably combine the stator and field current to acquire the maximum torque, meanwhile the energy conversion is taken into consideration by losses. Besides, on account of inductance influence by non-uniform air gap around rotor, nonlinear inductances and armature flux linkage against current variation are proposed to guarantee the results closer to reality. A computer-aided method for proposed algorithm are present and results are given in form of the Look-up table (LUT). The experiment shows the validity of algorithm.