• Biomedical Science Letters
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• v.26 no.2
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• pp.66-74
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• 2020

This study was carried out to investigate the protective effect of crude saponin from Platycodon grandiflorum on Clinical chemical parameters in male rats acutely exposed to 2,3,7,8-tetrachlorodibenzo-ρ-dioxin (TCDD). Crude saponin was prepared from Korean Platycodon grandiflorum with Diaion HP-20 adsorption chromatography after extraction of 80% ethanol at 75℃. The crude saponin was confirmed by thin layer chrmatography. When compared with ginseng saponins, the crude saponin had both a few number of saponins and a broad distribution. Forty male rats (200±20 g) were divided into 4 groups. Normal control (NC) group received vehicle and saline; TCDD-treated (TT) group received TCDD (40 ㎍/kg, single dose) intraperitoneally; Platycodon grandiflorum saponin (PG5 and PG10) groups received crude saponin 5 mg/kg and 10 mg/kg (p.o), respectively, for 2 weeks before 1 week of TCDD-exposure. Increase of body weight was retarded greatly by TCDD-exposure. Body weight of animals in TT group was significantly decrease after 2 days of TCDD-exposure. However, body weights of animals in PG groups increased through the experimental perimental period, although the increasing rate was slower than that of NC group. Increases in contents of blood glucose, total cholesterol and triglyceride (TG) and activities of amylase, lipase, AST, ALT and LDH by toxic action of TCDD were significantly attenuated by crude saponin from Platycodon grandiflorum (P<0.05). In conclusion, these results suggest that crude saponin prepared from Korean Platycodon grandiflorum might be a member of useful protective agents against TCDD, which is one of the environmental hormones.

• Journal of the Korean Institute of Gas
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• v.18 no.5
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• pp.72-77
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• 2014

It is known that there is no demand for building the arctic environment in Korea. However, it is important to use the different energy source instead of fuel source due to global warming. It is now demanded of using gas of Alaska and Siberia for long term developing the natural gas. The design of gas pipelines in Korea is very different from the arctic region. The operation of gas in arctic region have to consider of arctic region such as permafrost and active regions. It is needed to understand of gas pipeline design with different arctic soil properties. Nowadays, the pipelines is designed with stress-based and but there is demanded for strain based design with more deformed pipeline. We study of arctic environment with different active region using Finite Element Method of thermal elasto-plastic analysis.

• Industry Promotion Research
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• v.8 no.2
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• pp.45-59
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• 2023

In response to the increasing global competition for technological supremacy to address climate change, it is crucial to develop workforce development programs in the field of climate technology to accumulate the national technological capabilities. However, these programs are rarely monitored and evaluated, and research related to monitoring and evaluation in the field of climate technology workforce development is limited. Therefore, this study aimed to investigate the impact of workforce development programs in hydrogen energy and policy sectors on students' R&D capabilities and career aspirations in these sectors. The survey and focus group interviews with beneficiaries revealed that individual students' R&D capabilities and career confidence improved, and group-level R&D capabilities were also enhanced, and students felt greater appreciation on the significance of climate technology. The results of this study suggest that the necessary R&D capabilities to train R&D workforce in climate technology have been developed, but more measures are required to promote career development in this field.

• Journal of Digital Convergence
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• v.14 no.6
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• pp.9-19
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• 2016

Since continuous expand in governmental R&D investments and growth number of research institutions, model of multi-agency program has been planned and pushed ahead to settle the inefficiency of investment by the scattered and competitive R&D Programs. However, it was often pointed out that new model's effect has been fall because the institutional inertia of cooperative system between agencies. In this study, we analyze the current state of multi-agency program and suggest the optimal R&D governance model to improve a better direction. Afterward, several problems were turned up and that allocation and execution of the R&D budget separately, less coordination and cooperation among agencies, and absence of typical evaluation system of multi-agency program. Therefore, we suggest some of improvements by analyzing each steps.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.2
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• pp.212-220
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• 2021

National R&D investment has steadily increased, reaching number 5 in the world as of 2018. However, for public technology commercialization, the level of discovery of policy models through various cooperation initiatives between government ministries is insufficient, and the performance system that can spread technology commercialization is also limited. In this respect, in order to create results in public technology commercialization, it is necessary to prepare alternatives to strengthen multi-ministerial policy cooperation and increase policy execution power. In this paper, we analyzed the current state of national R&D projects by major ministries and suggested an optimized technology commercialization plan through analysis of the structure, budget, and form of each project. In particular, an alternative in terms of policy efficiency was suggested by analyzing the problems of policy discovery that have not been studied previously. This study is of great significance in that it diagnosed problems of public technology commercialization in terms of the lack of systematic research on public technology commercialization and suggested policy advancement for the spread of technology use and the strategic direction in terms of commercialization.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.12
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• pp.3761-3767
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• 2009

This study was investigated to determine the combustion characteristics, decomposition efficiency, and the flue gas concentrations after combustion in the high temperature reactor($1,250{\sim}1,400^{\circ}C$, 1 atm) for the liquid wastes(waste oil and waste solvent) generated from the industrial complex. The concentration of nitrogen oxide(NOx) is decreased and the synthetic gas is increased when the mass ratio of $O_2$/waste is about 1.53 because the reaction condition was changed to reduction state. And BTEXs(benzene, toluene, ethylbenzene, xylene) are decomposed more than 99.99%. If the highly concentrated liquid waste (waste oil and waste solvent) is treated under the operating conditions suggested by this study, our treatment method for the liquid waste was found to be proper because of the contaminants emission concentration is very low. In addition, the synthetic gas after combustion can be used as an alternative fuel.

• Journal of Korea Technology Innovation Society
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• v.13 no.1
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• pp.1-27
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• 2010

In this paper We analyze the correlation between investment and performance of Korean R&D programs, by six factors diversified, based on evolutionary economics of technology. National Science and Technology Information Service(NTIS) started from March, 2008 was used for collecting investment and performance data of national R&D program. We search the investment cost according to science-technology standard classification of Korea, research conductors, socio-economic objectives and cooperation types per year from 2002 to 2008, and we regard this data as "investment". Similarly, we search the number of papers, patents, commercializations, royalties and so forth according to science technology standard classification of Korea, research organizations, socio-economic objectives and cooperation types per year from 2002 to 2008, and this data is regarded as "performance". We expected analysis results of this investment and performance data confirm the diversified factors to affect advancement of science and technology. And we though, as a result, we will get some meaningful directions of investment of national R&D from the analysis results. But this study has several limitations because we did not consider enough microscopic characteristics of sector or technology, research organizations, cooperation network types, and external effect of social, politic, cultural factors.

• Journal of Korea Technology Innovation Society
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• v.15 no.3
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• pp.722-743
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• 2012

Confronted with increasing global competition and rising research and development risks, the global open innovation has receiving increased attention. This study empirically investigates whether or not international cooperative R&D is effective by evaluating the quality indicators with the patents with international co-applications. The number of patents with international co-applications has dramatically increased in recent years. According to the results, the outcome from international cooperative R&D is prominent in term of all the evaluation criteria such as the number of citation, patent families, claims, and et cetera, compared with that from domestic cooperative R&D. Based on the patent quality, the information technology sector holds the top spot and high-tech sectors such as bio and automobile industries show the better quality performances. By identifying high betweeneess centrality in the network analysis of international cooperative R&D, the US is indicated as the most central country in such cooperative activity, and then Germany, the UK, Canada, and France come after.

• 한국신재생에너지학회:학술대회논문집
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• 2010.11a
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• pp.140-140
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• 2010

최근 정부가 저탄소 녹색성장을 새로운 국정비전으로 제시하고 혁신적 그린에너지 기술개발을 위해 연평균 20%이상의 R&D 예산을 증액하고 있는 상황에서 연구개발결과의 상용화율 제고를 위한 연구기획, 평가, 관리시스템의 개선이 시급한 실정이다. 특히 선진국의 경우 최근 3년간 에너지분야 R&D의 상용화율이 미국 35.9%, 유럽 46.8%로서 24.2%인 한국에 비해 매우 높다고 할 수 있다. 이와같은 격차가 존재하는 것에 대해서 다양한 요인을 생각해볼 수 있겠지만, 크게 시장적인 또는 산업적인 측면에서의 중요도를 기준으로 연구과제를 선정하지 못하고 있다는 점과 연구개발결과를 효율적으로 사업화하고 있지 못하고 있다는 점을 생각해볼 수 있다. 특히 에너지 분야는 대규모 자금의 초기소요 및 개발기술 상용화기간의 장기화등으로 인해 사업화 실적이 타산업대비 매우 저조한 편이다. 이와같은 연구결과의 사업화와 관련된 문제점을 극복하기 위한 노력으로 국내에서 다양한 형태의 기술사업화 지원프로그램이 운영괴고 있으나, 에너지 분야에 특화된 프로그램은 부족한 상황이다. 반면에 미국의 경우, 재생에너지 R&D분야 전문투자자 그룹인 클린테크그룹 등을 중심으로 2002년부터 현재까지 다수의 녹색기술분야에 특화된 기술사업화 지원 프로그램을 운영하고 있다. 그 결과 현재까지 약 9년간 총 16억$의 투자유치에 성공함으로써 민간투자 활성화 역할을 담당하고 있다. 따라서 국내의 경우에도 이와같은 에너지 R&D 결과를 효과적으로 사업화로 연계시킬 수 있는 관련 프로그램 등이 시급히 도입되어야 할 것이다. 본 논문에서는 국내의 사업화 부진문제를 해결하기 위한 하나의 방안으로서 올해부터 정부주관으로 시행되고 있는 녹색인증사업을 활용하여 사업화가 유망한 기술 및 기업을 선별하고, 이에 대해 사업화 지원을 위한 후속프로그램을 적극 지원함으로써 연구개발결과의 경제적 활용도를 획기적으로 개선하는 방안을 제시하고자 한다. 또한 사업화 지원프로그램의 효율성을 높이기 위해 수도권, 영남권, 호남권 등 지역별 TP 등을 중심으로 기술사업화 협력 네트워크를 구축하고, 이를 기반으로 한 수요기술조사, 기술마케팅, 투자자유치 등의 관련프로그램을 개발하여 전단의 시스템과 융합시킴으로써 향후의 정부주도 R&D결과의 상용화율을 제고할 수 있는 시스템을 제안하고자 한다. 이에는 에너지 R&D분야별 기술적 시장적 특징분석, 지역별 산업특성과 기술공급 서플라이 체인분석을 토대로 한 기술이전 잠재수요기업 투자자를 대상으로 한 맞춤형 기술사업화 프로그램 등이 포함된다. 마지막으로 제안된 시스템에 대한 타당성 검증을 위해 올해년도에 시행한 녹색인증 기술사업화 연계프로그램 및 기술사업화 협력네트워크 활용사례 등을 분석하고, 향후 발전방향으로서 기술사업화 유관기관간간 기술사업화 정보교환 및 사업화 유망기술 기업 마케팅 등을 기본내용으로 한 시장지향적 녹색에너지 R&D 관리 시스템 구축방안을 제시하고자 한다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.2
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• pp.858-864
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• 2011

There is no standard model for a Stated Period Check and a Precise Safety Diagnosis to remove electric fire and shock in the university Lab and institute. Especially, the research for the Stated Period Check and the Precise Safety Diagnosis of the Lab related to electrical field is very weak currently, and it is very necessary to build a detail safety plan. This paper informs the specific standard guideline of the safety check list, method and equipment and it shows the way to evaluate safety grade too. This paper also provides the information of R&D process through the analysis of electrical safety check list of ordinary R&D Lab. It shows a new detail guideline to R&D Lab, and the new guideline removes existing problem and deliver the effective standard model to each R&D Lab. The standard model developed in this research adopts the clear guideline of each check list for the electrical environment of current R&D Lab. This standard model can be applied for every R&D Lab to detect routine safety check and detail safety check immediately. This Research will generally improve not only the effective safety check, but also the safety level for R&D Lab to prevent the electrical accidents.