• Advances in Traditional Medicine
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• v.7 no.2
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• pp.128-132
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• 2007

Diarun plus, a polyherbal formulation containing herbal ingredients of folkloric Antidiabetic effect, was investigated for its effect on glycemic status in rats and mice. In contrast to conventional chemical induced diabetic animal models, changes in glycemic states were induced by physiological maneuvers. Results revealed that in euglycemic animals Diarun plus elicited little change (-10 to +10%), which was insignificant. In food deprivation/swim exercise induced hypoglycemia, Diarun plus reduced the degree of hypoglycemia in both rats and mice (from 38% to 27% in rats and 45% to 32% in mice). Similarly, the marked hyperglycemia induced by dextrose (70% in rats and 95% in mice) was reduced markedly to 8% and 25% respectively. The findings of the present study suggests that the ingredients of Diarun plus have the unique property of maintaining near euglycemic state irrespective of the altered glycemic state, and that have no significant effect in euglycemic condition.

• Journal of muscle and joint health
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• v.25 no.2
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• pp.112-121
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• 2018

Purpose: This study was conducted to explore the mediating effect of nutritional status on the relationship between symptom experience and functional status of patients with Chronic Obstructive Pulmonary Disease (COPD). Methods: A total of 141 COPD patients visiting D hospital and I hospital in B city were enrolled in this study. Data were collected from January 2017 to July 2017. Outcome variables were measured by Mini Nutritional Assessment Short-Form (MNA-SF) for nutritional status, The Memorial Symptom Assessment Scale (MSAS) for symptom experience, and The Functional Performance Inventory Short Form (FPI-SF) for functional status. The data were analyzed with descriptive statistics, Pearson's correlation, and path analysis using SPSS/WIN 21.0 and AMOS 25. Results: There was a significant negative correlation between symptom experience and nutritional status (r=-.61, p<.001), a significant negative correlation between symptom experience and functional status (r=-.40, p<.001), and significant positive correlation between nutritional status and functional status (r=.47, p<.001). Symptom experience had indirect effects on functional status through nutritional status. Conclusion: For enhancing functional status in COPD patients, it is necessary to develop nursing intervention programs to enhance symptom management as well as nutritional status.

• Journal of Korea Technology Innovation Society
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• v.21 no.1
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• pp.201-235
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• 2018

With the recent slowdown of R&D budget growth rate, efficient resource allocation, operation and management of national R&D is becoming more important. At this point, recognizing the necessity of systematic and scientific research on the national R&D itself, this study analyzed previous researches on national R&D of Korea. In this study, based on the previous researches and laws, national R&D was classified according to the major stages such as planning, selection, management, performance and so on. Secondly, by using the classification criteria forged, previous researches on the national R&D published in domestic journals for the last 5 years were divided into 12 categories, and the status of researches in each field was analyzed. Lastly, through network analysis, linking status and influence of each fields were identified by using co-classification information of research literatures. As a result of this research, the performance related fields were the most active ones in terms of the number of research literatures, and connections with other fields, while the fields such as selection and infrastructure were lacking in the number of research and linkage. This study can find its meaning in identifying research fields that need more studies and connections with other areas by systematic analysis of previous studies on Korean National R&D.

• Environmental and Resource Economics Review
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• v.13 no.3
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• pp.469-497
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• 2004

Environmental R&D management system has been analyzed with LCA method. Based on the analysis, we found the following four elements were essential for improving effciency of environmental R&D management system: establishment of an information clearinghouse that collects and distributes information on the status of the domestically owned environmental technology, Periodic survey of the environmental technology demand to give guidance in selecting the environmental R&D project that are to be subsidized, dissemination of information on the technology transfer and commercialization assistance program, and increased funding as well as the expansion of project categories eligible for R&D subsidy.

• Korea Trade Review
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• v.45 no.1
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• pp.47-64
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• 2020

For the past few years, the Korean government has been consistently expanding its national research & development budget to accelerate economic growth through technology innovation and the enhancement of international competitiveness in global markets. The objective of this paper is to define the concept and analyze the current status of national R&D programs by measuring R&D efficiencies. We determine R&D efficiency by reflecting inputs and outcomes of the five main agricultural R&D programs between 2010 to 2015, and by categorizing and regrouping figures that may affect R&D performance. Among 1,128 targeted projects, 832 projects with patents and thesis were selected for analysis in terms of measuring technology efficiency, pure technology efficiency, and efficiency of scale. Also, the Kruskal-Wallis test was also utilized as well. As a result of empirical analysis, figures that affected the efficiency level of national R&D programs included differences in research resources, research management levels and skills, and research field. This study can be utilized as a reference for re-establishing national agricultural R&D policies, such as enhancement of national technology competitiveness in the global market environment, improving and adapting to new agricultural conditions, market expansion, national agricultural R&D efficiency, aging rural population, agricultural management cost increase, and climate change mitigation.

• Proceedings of the KIEE Conference
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• 1994.07a
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• pp.488-490
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• 1994

To meet the requirements of high performance and reliability as a industrial motor drive, we developed an integrated oil-line fault diagnosis and monitoring system which consists of DSP-based controller and PC-based MMI (Man-machine interface) program. The dedicated controller performs real-lime fault detections and protections. The MMI program monitors the on-line fault status of the drive system and offers full explanations of the fault name(WHAT?), deducible causes of the fault operation(WHY?), and chock points (HOW?) based upon the experiences of the expert. Also the TRACE data which was stored just before and after the accident can be scrutinized using MMI tools.

• Tissue Engineering and Regenerative Medicine
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• v.15 no.6
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• pp.699-709
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• 2018

BACKGROUND: Diabetes mellitus is a major health concern in current scenario which has been found to affect people of almost all ages. The disease has huge impact on global health; therefore, alternate methods apart from insulin injection are being explored to cure diabetes. Therefore, this review mainly focuses on the current status and therapeutic potential of stem cells mainly mesenchymal stem cells (MSCs) for Type 1 diabetes mellitus in preclinical animal models as well as humans. METHODS: Current treatment for Type 1 diabetes mellitus mainly includes use of insulin which has its own limitations and also the underlying mechanism of diseases is still not explored. Therefore, alternate methods to cure diabetes are being explored. Stem cells are being investigated as an alternative therapy for treatment of various diseases including diabetes. Few preclinical studies have also been conducted using undifferentiated MSCs as well as in vitro MSCs differentiated into ${\beta}$ islet cells. RESULTS: These stem cell transplant studies have highlighted the benefits of MSCs, which have shown promising results. Few human trials using stem cells have also affirmed the potential of these cells in alleviating the symptoms. CONCLUSION: Stem cell transplantation may prove to be a safe and effective treatment for patients with Type 1 diabetes mellitus.

• Journal of Appropriate Technology
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• v.5 no.1
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• pp.25-32
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• 2019

In this article, we examine the current status and problems of research and development of social problem solving in university. Social problem solving R&D is characterized by pursuing social goals and participatory research and development. This paper summarizes the problems faced by the social problem solving R & D in the university and the remedies based on the focus group interview. 1) Establishment of 'the Social problem-solving R&D center' to create a base for embedding social problem-solving R&D within the university; 2) To develop and disseminate social problem solving research and development models suitable for universities; 3) Activation plans for vitalizing the participation of mainstream researchers and civil society in the social problem solving R&D were discussed.

• Food Science and Industry
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• v.53 no.3
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• pp.307-315
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• 2020

The food R&D operating system needs to be changed according to the changes in the food industry as well as the domestic and overseas environments. In this aspect, a future-oriented food R&D operating strategy linked with the governmental policy are proposed to foster the promising food industry. The strategic R&D approaches are summarized on the basis of global mega-trends and food industry trend analysis, and current R&D status and issues are also reviewed to set the R&D operating direction for future food industry. To advance the R&D operating system of the food industry, some practical suggestions are given as follows: strengthening the research planning system for efficient R&D program operation, enhancing the role assignment and collaboration among the R&D organizations, reinforcing the support system tailored to industrial sites and securing the future technology bases as well as resolving present issues, and linking R&D programs with policies and improving the food R&D management system.

• Korean Journal of Human Ecology
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• v.4 no.1
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• pp.36-45
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• 2001

This study was performed to determine the changes of maternal iron status during pregnancy cross sectionally, and to evaluate the appropriateness of the cut-off points of hemoglobin (Hb). hematocrit (Hct), serum transferrin receptor (sTfR) and sTfR : ferritin ratio for assessing iron deficiency status based on serum ferritin level (< 12${\mu}g$/L). Serum Hb concentrations in the first trimester were significantly higher (p < 0.05) than those in the second and third trimester. Serum levels of iron and ferritin in the third trimester were significantly lower (p < 0.05) than those in the first and second trimester. On the other hand, sTfR:ferritin ratios in the third trimester were significantly higher (p < 0.05) than those in the first and second trimester. sTfR concentrations did not change significantly during pregnancy. The appropriate cut-off points of Hb were 11.5g/dL for whole period of pregnancy. 12.0g/dL for 1st trimester. and 11.5g/dL for both 2nd and 3rd trimester. The good cut-off points of Hct were 34% for whole period of pregnancy. 36% for 1st trimester. and 34% for both 2nd and 3rd trimester The suitable cut-off points of TIBC were 400${\mu}g$/dL for whole period of pregnancy. 360${\mu}g$/dL for 1st trimester, and 400${\mu}g$/dL for both 2nd and 3rd trimester. Any cut-off point of sTfR could not be selected because of its low sensitivity and specificity. The proper cut-off point of sTfR : ferritin ratio was 600 or 650 for all the periods determined except the first trimester. In conclusion, there were no reliable cut-off levels of sTfR and those of sTfR : ferritin ratio showed low specificity. The cut-off values of Hb and Hct for assessing iron deficiency were slightly higher than the values used to evaluate anemia. Thus, if appropriate cut-off levels were applied, Hb. Hct, or TIBC might be useful indices for evaluating iron deficiency as well as anemia.